Peptide

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MOTS-c (human)
MOTS-c (human)

Artikelnummer: AG-CP3-0026-M001

Solid lyophilized powder. Soluble in water. Mitochondria-derived peptide (MDP), Promotes biosynthesis of the endogenous AMP analog AICAR and consequently AMP-activated protein kinase (AMPK), Induces cellular and systemic glucose uptake and improves insulin sensitivity. Shown to prevent diet-induced obesity (DIO) in...
Schlagworte: H-Met-Arg-Trp-Gln-Glu-Met-Gly-Tyr-Ile-Phe-Tyr-Pro-Arg-Lys-Leu-Arg-OH . TFA, Mitochondrial Open Reading Frame of the 12S...
Anwendung: Mitochondria-derived peptide, AMPK promoter
CAS 1627580-64-6
MW: 2288,6 D
ab 165,00 €
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Sermorelin
Sermorelin

Artikelnummer: Cay24113-500

Sermorelin is a 29-residue N-terminal analog of growth hormone-releasing hormone (GHRH) that retains the ability to stimulate growth hormone (GH) release. Sermorelin (1 µg/kg, i.v.) increases serum GH levels in rats by approximately 17% compared with saline control after 15 minutes. It also increases GH release in...
Schlagworte: Growth Hormone-Releasing Factor (1-29) Amide, hGH-RH(1-29)-NH2, hGRF(1-29)NH2, hpGRF(1-29)NH2,...
Anwendung: GHRHR ligand
CAS 86168-78-7
MW: 3357.9 D
ab 124,00 €
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Z-AEVD-FMK
Z-AEVD-FMK

Artikelnummer: Cay14987-500

Z-AEVD-FMK is an irreversible inhibitor of caspase-10 and related caspases. At 10 µM, it can prevent the initiation of Fas signaling by caspase-10 in Jurkat T lymphoma cells, preventing Bid cleavage into its active form, caspase cascade activation, and apoptosis.
Schlagworte: Z-Ala-Glu-Val-Asp-Fluoromethyl Ketone,...
Anwendung: Irreversible caspase-10 inhibitor
CAS 1135688-47-9
MW: 610.6 D
ab 69,00 €
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Ac-LETD-AFC
Ac-LETD-AFC

Artikelnummer: Cay14991-5

Ac-LETD-AFC is a fluorogenic substrate that can be cleaved specifically by caspase-8. Caspase activity can be quantified by fluorescent detection of free AFC (also known as 7-amino-4-trifluoromethylcoumarin), which is excited at 400 nm and emits at 505 nm.
Schlagworte: Caspase-8 Substrate (Fluorogenic), N-Acetyl-Leu-Glu-Thr-Asp-7-amido-4-Trifluoromethylcoumarin,...
Anwendung: Fluorogenic Caspase-8 substrate
CAS 210345-02-1
MW: 729.7 D
ab 78,00 €
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PAR2 (1-6) (mouse, rat)
PAR2 (1-6) (mouse, rat)

Artikelnummer: Cay27125-5

PAR2 (1-6) is a synthetic peptide agonist of proteinase-activated receptor 2 (PAR2) that corresponds to residues 1-6 of the amino terminal tethered ligand sequence of mouse and rat PAR2. It also corresponds to residues 39-44 and 37-42 of the mouse and rat full-length sequences, respectively. PAR2 (1-6) induces...
Schlagworte: SLIGRL, L-seryl-L-leucyl-L-isoleucylglycyl-L-arginyl-L-leucine
Anwendung: Synthetic peptide PAR2 agonist
CAS 164081-25-8
MW: 657.8 D
ab 44,00 €
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PAR4 (1-6) (human)
PAR4 (1-6) (human)

Artikelnummer: Cay27126-50

PAR4 (1-6) is a peptide agonist of proteinase-activated receptor 4 (PAR4) that corresponds to residues 1-6 of the amino terminal tethered ligand sequence of human PAR4 and residues 48-53 of the full-length sequence. It activates PAR4 and the cleavage site mutant PAR4R47A when used at a concentration of 500 µM. PAR4...
Schlagworte: GYPGQV, glycyl-L-tyrosyl-L-prolylglycyl-L-glutaminyl-L-valine
Anwendung: Synthetic peptide PAR4 agonist
CAS 225779-44-2
MW: 619.7 D
ab 162,00 €
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PAR3 (1-6) (human)
PAR3 (1-6) (human)

Artikelnummer: Cay27129-500

PAR3 (1-6) is a synthetic peptide agonist of proteinase-activated receptor 1 (PAR1) that corresponds to residues 1-6 of the amino terminal tethered ligand sequence of human PAR3 and residues 39-44 of the full-length human sequence. PAR3 (1-6) activates p42/44 MAPK signaling in fibroblasts expressing PAR1, but not...
Schlagworte: TFRGAP, L-threonyl-L-phenylalanyl-L-arginylglycyl-L-alanyl-L-proline
Anwendung: Synthetic peptide PAR1 agonist
CAS 320347-28-2
MW: 647.7 D
ab 69,00 €
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Acetyl Tetrapeptide-3
Acetyl Tetrapeptide-3

Artikelnummer: Cay27151-50

Acetyl tetrapeptide-3 is a biomimetic peptide. It increases protein levels of type III collagen and total laminins in MRC5 human fibroblasts when used at a concentration of 1 µM. Acetyl tetrapeptide-3 reverses corticoid-induced decreases in collagen VII expression at the dermal-epidermal junction in human skin...
Schlagworte: N2-acetyl-L-lysylglycyl-L-histidyl-L-lysinamide
Anwendung: Biomimetic peptide
CAS 827306-88-7
MW: 509.6 D
ab 32,00 €
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Biotin Tripeptide-1
Biotin Tripeptide-1

Artikelnummer: Cay27153-50

Biotin tripeptide-1 is an extracellular matrix (ECM) peptide that has been conjugated to biotin (Cay-22582). It stimulates the production of collagen IV and laminin in dermal and epidermal cells ex vivo. Biotin tripeptide-1 localizes to the peri-pilial zone of isolated cultured human hair follicles, induces...
Schlagworte: Biotinoyl Tripeptide-1, Biotinyl-GHK, Biotinyl-Gly-His-Lys,...
Anwendung: Biotinylated extracellular matrix (ECM) peptide
CAS 299157-54-3
MW: 566.7 D
ab 32,00 €
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GHK
GHK

Artikelnummer: Cay27168-5

GHK is a peptide released during extracellular matrix (ECM) protein degradation following tissue injury. It binds to copper to form GHK-Cu, a complex with diverse biological activities, including roles in tissue remodeling and wound healing, hair growth, and suppression of inflammation. GHK (1 µM) increases...
Schlagworte: Gly-His-Lys, NSC 379527, glycyl-L-histidyl-L-lysine
Anwendung: Tissue injury extracellular matrix (ECM) protein degradation peptide
CAS 49557-75-7
MW: 340.4 D
ab 32,00 €
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CAP 3
CAP 3

Artikelnummer: Cay27505-5

CAP 3 is a cholic acid-peptide conjugate (CAP) with antibacterial activity. It is active against the Gram-negative bacteria E. coli, K. pneumoniae, and A. baumanii (MIC99s = 8, 16, and 16 µM, respectively). CAP 3 increases the fluidity of model Gram-negative bacterial membranes and binds to LPS in vitro. It reduces...
Schlagworte: (3R,5S,7R,8R,9S,10S,12S,13R,14S,17R)-17-((R)-5-(benzyloxy)-5-oxopentan-2-yl)-10,13-dimethylhexadecahydro-1H-cyclopenta[a]p...
Anwendung: Antibacterial cholic acid-peptide conjugate (CAP)
MW: 967.3 D
ab 62,00 €
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Histone H3 (23-34) (human, mouse, rat, bovine) (trifluoroacetate salt)
Histone H3 (23-34) (human, mouse, rat, bovine)...

Artikelnummer: Cay28139-1

Histone H3 (23-34) is a peptide fragment of histone H3 that corresponds to amino acid residues 24-35 of the human histone H3.1 and H3.2 sequences. It contains lysine residues at positions 23 and 27 that are subject to methylation and acetylation and have a role in the regulation of gene expression and a serine...
Schlagworte: KAARKSAPATGG, L-lysyl-L-alanyl-L-alanyl-L-arginyl-L-lysyl-L-seryl-L-alanyl-L-prolyl-L-alanyl-L-threonylglycylglycine,...
Anwendung: Peptide fragment, Methylation / acetylation / phosphorylation studies
MW: 1114.3 D
249,00 €
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