Peptide

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Ac-DEVD-AFC
Ac-DEVD-AFC

Artikelnummer: ABD-13401

A fluorogenic substrate for caspase 3. The 7-amido-4-trifluoromethylcoumarin derivatives have better membrane permeability than the 7-amido-4-methylcoumarin derivatives.
Anwendung: Caspase-3 substrate
CAS 201608-14-2
112,00 €
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(Z-DEVD)2-R110
(Z-DEVD)2-R110

Artikelnummer: ABD-13430

Cleavage of R110 peptides by caspases generates strongly fluorescent R110 that can be monitored fluorimetrically at 510-530 nm with excitation of 488 nm.This R110 substrate is specific for caspases 3 and 7.
Anwendung: Caspase-3 substrate, Caspase-7 substrate
112,00 €
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Ac-DEVD-AMC
Ac-DEVD-AMC

Artikelnummer: ABD-13402

A fluorogenic substrate for caspase 3, a protease that is rapidly activated when cells are exposed to apoptotic conditions and that cleaves poly(ADP-ribose) polymerase.
Anwendung: Caspase-3 substrate
CAS 169332-61-0
112,00 €
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(Ac-PAL)2R110
(Ac-PAL)2R110

Artikelnummer: ABD-13467

The non-fluorescent R110 substrates generate the bright green fluorescent rhodamine 110 product that has Ex/Em = 494/521 nm, and can be easily detected with a FITC filter set. In general, R110 substrates are much more sensitive than the AMC-, AFC- or 4-nitroaniline-based substrates. This R110 substrate is used for...
Anwendung: Protease substrate
112,00 €
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3,3',5'-Triiodo-L-thyronine
3,3',5'-Triiodo-L-thyronine

Artikelnummer: Cay17598-50

3,3',5'-Triiodo-L-thyronine, also known as reverse T3 (rT3), is a thyroid hormone generated by deiodination of the prohormone thyroxine. It is about 1,000-fold less active at the thyroid hormone receptors TRalpha and TRbeta than 3,3',5-triiodo-L-thyronine (Cay-16028) and commonly described as inactive. However, high...
Schlagworte: 3,3',5'-T3, Reverse T3, rT3, O-(4-hydroxy-3,5-diiodophenyl)-3-iodo-L-tyrosine
Anwendung: TR Delta alpha1 activator
CAS 5817-39-0
MW: 651 D
ab 82,00 €
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Angiotensin II (human)
Angiotensin II (human)

Artikelnummer: Cay17150-25

Angiotensin II is a peptide hormone known best as a vasoconstrictor with central roles in chronic hypertension, heart failure, and stroke. It is an octapeptide typically generated by the removal of two residues from angiotensin I by angiotensin-converting enzyme (ACE). Angiotensin II is a ligand for at least two...
Schlagworte: 5-L-isoleucine-angiotensin II
Anwendung: Peptide hormone
CAS 4474-91-3
MW: 1046.2 D
ab 24,00 €
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NEU
MCL-1 Peptide Ligand
MCL-1 Peptide Ligand

Artikelnummer: BPS-79507

MCL-1 Peptide Ligand is useful as a substrate for screening services and optimized for use with the following TR-FRET assay kits: * MCL-1 TR-FRET Assay kit (BPS-79506) * MCL-1 TR-FRET Assay kit (Mouse) (BPS-79928)
Anwendung: Substrate, Screening, TR-FRET
MW: 3162 D
247,00 €
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NEU
Ac-QPKK(Ac)-AMC
Ac-QPKK(Ac)-AMC

Artikelnummer: Cay30790-1

Ac-QPKK(Ac)-AMC is a fluorogenic substrate for sirtuin 1 (SIRT1), SIRT2, and SIRT3. It is selectively deacylated by SIRT1-3 over SIRT6. Upon enzymatic cleavage by SIRT1, SIRT2, or SIRT3, 7-amino-4-methylcoumarin (AMC) is released and its fluorescence can be used to quantify SIRT1, SIRT2, and SIRT3 activity. AMC...
Schlagworte: Ac-Gln-Pro-Lys-Lys-(Ac)-7-amino-4-methylcoumarin, Ac-Gln-Pro-Lys-Lys-(Ac)-AMC, p53317-320 Substrate (Ac-QPKK(Ac)-AMC),...
Anwendung: Fluorogenic SIRT1 substrate
CAS 1387005-23-3
MW: 740.9 D
ab 74,00 €
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NEU
Z-(L-Arg)-AMC (hydrochloride)
Z-(L-Arg)-AMC (hydrochloride)

Artikelnummer: Cay30797-10

Z-(L-Arg)-AMC is a fluorogenic substrate for trypsin, cathepsin B, and cathepsin H. Upon enzymatic cleavage by trypsin, cathepsin B, or cathepsin H, 7-amino-4-methylcoumarin (AMC) is released and its fluorescence can be used to quantify trypsin, cathepsin B, and cathepsin H activity. AMC displays excitation/emission...
Schlagworte: Bz-Arg-AMC, N-benzoxy-L-Arg-7-amido-4-methylcoumarin, N-benzoyl-L-Arg-AMC, Z-Arg(HCl)AMC,...
Anwendung: Fluorogenic trypsin substrate
CAS 70375-22-3
MW: 502 D
ab 69,00 €
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NEU
Z-Lys-OMe (hydrochloride)
Z-Lys-OMe (hydrochloride)

Artikelnummer: Cay30804-1

Z-Lys-OMe is a synthetic intermediate. It has been used in the synthesis of peptide enzyme substrates and lysine cationic surfactants.Formal Name: N2-[(phenylmethoxy)carbonyl]-L-lysine, methyl ester, monohydrochloride. CAS Number: 26348-68-5. Molecular Formula: C15H22N2O4 . HCl. Formula Weight: 330.8. Purity: >98%....
Schlagworte: N2-[(phenylmethoxy)carbonyl]-L-lysine, methyl ester, monohydrochloride
Anwendung: Synthetic intermediate
CAS 26348-68-5
MW: 330.8 D
ab 33,00 €
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NEU
Z-Lys-OBzl (benzenesulfonate)
Z-Lys-OBzl (benzenesulfonate)

Artikelnummer: Cay30916-1

Z-Lys-OBzl is an amino acid-containing building block. It has been used in the synthesis of lysine peptide derivatives and glucosepane.Formal Name: N2-[(phenylmethoxy)carbonyl]-L-lysine, monobenzenesulfonate. CAS Number: 68973-36-4. Molecular Formula: C21H26N2O4 . C6H6O3S. Formula Weight: 528.6. Purity: >98%....
Schlagworte: N2-[(phenylmethoxy)carbonyl]-L-lysine, monobenzenesulfonate
Anwendung: Amino acid-containing building block
CAS 68973-36-4
MW: 528.6 D
ab 37,00 €
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NEU
Boc-D-Phe-Pro-OH
Boc-D-Phe-Pro-OH

Artikelnummer: Cay31151-1

Boc-D-Phe-Pro-OH is a synthetic intermediate. It has been used in the synthesis of peptide thrombin inhibitors.Formal Name: N-[(1,1-dimethylethoxy)carbonyl]-D-phenylalanyl-L-proline. CAS Number: 38675-10-4. Synonyms: Boc-D-FP-OH. Molecular Formula: C19H26N2O5. Formula Weight: 362.4. Purity: >98%. Formulation: A...
Schlagworte: Boc-D-FP-OH, N-[(1,1-dimethylethoxy)carbonyl]-D-phenylalanyl-L-proline
Anwendung: Synthetic intermediate
CAS 38675-10-4
MW: 362.4 D
ab 32,00 €
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