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Ac-DEVD-AFC
Artikelnummer: ABD-13401
A fluorogenic substrate for caspase 3. The 7-amido-4-trifluoromethylcoumarin derivatives have better membrane permeability than the 7-amido-4-methylcoumarin derivatives.
| Anwendung: | Caspase-3 substrate |
| CAS | 201608-14-2 |
139,00 €
(Z-DEVD)2-R110
Artikelnummer: ABD-13430
Cleavage of R110 peptides by caspases generates strongly fluorescent R110 that can be monitored fluorimetrically at 510-530 nm with excitation of 488 nm.This R110 substrate is specific for caspases 3 and 7.
| Anwendung: | Caspase-3 substrate, Caspase-7 substrate |
139,00 €
Ac-DEVD-AMC
Artikelnummer: ABD-13402
A fluorogenic substrate for caspase 3, a protease that is rapidly activated when cells are exposed to apoptotic conditions and that cleaves poly(ADP-ribose) polymerase.
| Anwendung: | Caspase-3 substrate |
| CAS | 169332-61-0 |
139,00 €
(Ac-PAL)2R110
Artikelnummer: ABD-13467
The non-fluorescent R110 substrates generate the bright green fluorescent rhodamine 110 product that has Ex/Em = 494/521 nm, and can be easily detected with a FITC filter set. In general, R110 substrates are much more sensitive than the AMC-, AFC- or 4-nitroaniline-based substrates. This R110 substrate is used for...
| Anwendung: | Protease substrate |
139,00 €
3,3',5'-Triiodo-L-thyronine
Artikelnummer: Cay17598-50
3,3',5'-Triiodo-L-thyronine, also known as reverse T3 (rT3), is a thyroid hormone generated by deiodination of the prohormone thyroxine. It is about 1,000-fold less active at the thyroid hormone receptors TRalpha and TRbeta than 3,3',5-triiodo-L-thyronine (Cay-16028) and commonly described as inactive. However, high...
| Schlagworte: | 3,3',5'-T3, Reverse T3, rT3, O-(4-hydroxy-3,5-diiodophenyl)-3-iodo-L-tyrosine |
| Anwendung: | TR Delta alpha1 activator |
| CAS | 5817-39-0 |
| MW: | 651 D |
ab 114,00 €
Angiotensin II (human) (acetate)
Artikelnummer: Cay17150-25
Angiotensin II is a peptide hormone known best as a vasoconstrictor with central roles in chronic hypertension, heart failure, and stroke. It is an octapeptide typically generated by the removal of two residues from angiotensin I by angiotensin-converting enzyme (ACE). Angiotensin II is a ligand for at least two...
| Schlagworte: | 5-L-isoleucine-angiotensin II, acetate |
| Anwendung: | Peptide hormone |
| CAS | 68521-88-0 |
| MW: | 1046.2 D |
ab 34,00 €
Glucagon (hydrochloride)
Artikelnummer: Cay24204-1
Glucagon is a peptide hormone produced from proglucagon in pancreatic alpha cells that has a role in the regulation of glucose metabolism. Pulsatile application of glucagon to rat hepatocytes stimulates glucose production ex vivo. It also stimulates glucose output from perfused rat livers via increases in...
| Schlagworte: | glucagon (swine) |
| Ursprungsart: | swine |
| CAS | 19179-82-9 |
| MW: | 3482.8 D |
ab 117,00 €
PI-3 Kinase Lipid Substrate
Artikelnummer: BPS-40560
PI/PS (4:1, w/w) unilamellar vesicle, prepared with L-alpha-phosphatidylinositol (Liver, Bovine) (sodium salt) and L-alpha-phosphatidylserine (Brain, Porcine) (sodium salt). Lipid monolayer was formed by sonication. Application: Useful as a substrate for PI-3 kinase activity assays and other lipid kinases....
| Anwendung: | PI-3 kinase substrate |
569,00 €
PPACK (hydrochloride)
Artikelnummer: Cay37489-5
PPACK is a synthetic peptide derivative that irreversibly and specifically inhibits thrombin-mediated platelet activation by binding with high affinity to the active site of thrombin (Ki = 0.24 nM). It has been used as an anticoagulant (100 µM) and to study thrombin-mediated fibrin deposition, angiogenesis, and...
| Schlagworte: | D-Phenylalanyl-prolyl-arginyl Chloromethyl Ketone, D-Phe-Pro-Arg-CH2Cl, Pebac,... |
| Anwendung: | Thrombin-mediated platelet activation inhibitor |
| CAS | 82188-90-7 |
| MW: | 523.9 D |
ab 48,00 €
NEU
Sulfo-SMCC (sodium salt)
Artikelnummer: Cay35692-100
Sulfo-SMCC is a water-soluble protein cross-linking reagent that contains an anime-reactive sulfo-N-hydroxysuccinimide (sulfo-NHS) ester and a sulfhydryl-reactive maleimide group that can be used in the conjugation of proteins. It has been used to conjugate anti-programmed cell death ligand 1 (PD-L1) antibodies to...
| Schlagworte: | Sulfosuccinimidyl 4-(N-maleimidomethyl)cyclohexane-1-carboxylate,... |
| Anwendung: | Water-soluble protein cross-linking reagent |
| CAS | 92921-24-9 |
| MW: | 436.4 D |
ab 92,00 €
NEU
LL-37 (13-37) (human) (trifluoroacetate salt)
Artikelnummer: Cay36949-1
LL-37 (13-37) is an anticancer peptide fragment of LL-37 (Cay-24461). It inhibits the ATPase activity of ATP-binding cassette transporter 2, subfamily G (ABCG2) when used at a concentration of 1 µM. LL-37 (13-37) induces cytotoxicity in wild-type SW620 cells and SW620 cells overexpressing P-glycoprotein (P-gp), also...
| Schlagworte: | CAP-18, Cathelicidin, FALL-39, hCAP-18, IG-25, LL-13, LL-25,... |
| Anwendung: | LL-37 anticancer peptide fragment |
| MW: | 3043.6 D |
ab 53,00 €
NEU
CXCL9 (74-103) (human) (trifluoroacetate salt)
Artikelnummer: Cay38849-1
Chemokine (C-X-C motif) ligand 9 (CXCL9) (74-103) is a C-terminal fragment of mature CXCL9. It binds to the glycosaminoglycan heparin in a cell-free assay (Kd = 3.1 nM). CXCL9 (74-103) inhibits the binding of CXCL8 or CXCL11 to heparin, as well as chemokine (C-C motif) ligand 2 (CCL2) binding to heparan sulfate, in...
| Schlagworte: | Chemokine (C-X-C motif) Ligand 9 (74-103), MIG30, Monokine Induced by Interferon-gamma (74-103) |
| Anwendung: | CXCL9-derived peptide |
| MW: | 3661.4 D |
ab 66,00 €