Produkte von Chimerigen Laboratories
Chimerigen produziert einzigartige Immunglobulin-basierte chimäre Fusionsproteine und verwandte Forschungs-Produkte mit Hilfe modernster zell-und molekularbiologischen Techniken. Diese Reagenzien werden erfolgreich in Grundlagenforschung und angewandter Forschung eingesetzt.
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IL-22 (mouse):Fc (mouse) (rec.) (non-lytic) Artikelnummer: CHI-MF-12022-C050
Interleukin-22 (IL-22), also known as IL-10 related T cell derived inducible factor (ILTIF) was initially identified as a gene induced by IL-9 in mouse T cells and mast cells. IL-22 has been shown to activate STAT1 and STAT3 in several hepatoma cell lines and upregulate the production of acute phase proteins. IL-22...
| Schlagworte: | Il22, Il22a, IL-22, IL-TIF, IL-22a, IL-TIF alpha, Interleukin-22, Interleukin-22a, IL-10-related T-cell-derived-inducible... |
| Anwendung: | Bioassays |
| Reaktivität: | Mouse |
ab 292,00 €
IL-35 (mouse):Fc (human) (rec.) Artikelnummer: CHI-MF-11135-C025
The mouse IL-35 complex composed of the Ebi3 subunit (aa 23-228) and the IL-12a (p35) subunit (aa 23-215) is fused through a polypeptide linker to the Fc portion of human IgG1. Lyophilized from 0.2µm-filtered solution in PBS. Interleukin-35 (IL-35) is a novel IL-12 family cytokine produced by regulatory T cells...
| Schlagworte: | Interleukin-35, Il12a, IL-12A, CLMF p35, IL-12 subunit p35, Interleukin-12 subunit alpha, Cytotoxic lymphocyte maturation... |
| Anwendung: | Bioassays |
| Reaktivität: | Mouse |
ab 292,00 €
IL-35 (human):Fc (human) (rec.) Artikelnummer: CHI-HF-21035-C025
The human IL-35 complex composed of the Ebi3 subunit (aa 21-229) and the IL-12a (p35) subunit (aa 57-253) is fused through a polypeptide linker to the Fc portion of human IgG1. Lyophilized from 0.2µm-filtered solution in PBS. Interleukin-35 (IL-35) is a novel IL-12 family cytokine produced by regulatory T cells...
| Schlagworte: | Interleukin-35, NKSF1, IL12A, IL-12A, CLMF p35, IL-12 subunit p35, Interleukin-12 subunit alpha, NK cell stimulatory... |
| Anwendung: | Bioassays |
| Reaktivität: | Human |
264,00 €
Galectin-9 (human):Fc (human) (rec.) Artikelnummer: CHI-HF-210GAL9-C050
The TIM (T cell/transmembrane, immunoglobulin and mucin) family plays a critical role in regulating immune responses, including allergy, asthma, transplant tolerance, autoimmunity and the response to viral infections. The unique structure of TIM immunoglobulin variable region domains allows highly specific...
| Schlagworte: | Gal-9, LGALS9, Ecalectin, Galectin-9, Tumor antigen HOM-HD-21, Gal-9, Ecalectin, TIM3L, TIM-3 Ligand, T Cell... |
| Anwendung: | Bioassays |
| Reaktivität: | Human |
352,00 €
Tim-4 (human):Fc (mouse) (rec.) Artikelnummer: CHI-HF-211T4-C100
The TIM (T cell/transmembrane, immunoglobulin and mucin) family plays a critical role in regulating immune responses, including allergy, asthma, transplant tolerance, autoimmunity and the response to viral infections. The unique structure of TIM immunoglobulin variable region domains allows highly specific...
| Schlagworte: | TIM4, TIMD4, TIM-4, TIMD-4, T-cell membrane protein 4, T-cell immunoglobulin mucin receptor 4, T-cell immunoglobulin and... |
| Anwendung: | Bioassays |
| Reaktivität: | Human |
| MW: | ~80 kD |
473,00 €
CD274 [B7-H1/PD-L1] (human):Fc (human) (rec.) Artikelnummer: CHI-HF-210PDL1-C100
The extracellular domain of human CD274 [B7-H1] (aa 19-238) is fused to the N-terminus of the Fc region of human IgG1. Lyophilized from 0.2µm-filtered solution in PBS. Programmed death ligand 1 (PD-L1, B7-H1 or CD274) is a member of the growing B7 family of immune proteins that provide signals for both stimulating...
| Schlagworte: | B7H1, B7-H1, CD274, PD-L1, B7 homolog 1, PDCD1 ligand 1, Programmed death ligand 1, Programmed cell death 1 ligand 1 |
| Anwendung: | Bioassays |
| Reaktivität: | Human |
385,00 €
IL-22 (human):Fc (human) (rec.) (non-lytic) Artikelnummer: CHI-HF-22022-C050
The extracellular domain of human IL-22 (aa 34-179) is fused at the C-terminus to the Fc portion of a mutant human IgG1. Lyophilized from 0.2µm-filtered solution in PBS. Shows the biological function of the IL-22 moiety and exerts a prolonged circulating half-life caused by the modified Fc domain. Interleukin-22...
| Schlagworte: | IL22, IL-22, ILTIF, IL-TIF, Interleukin-22, Cytokine Zcyto18, IL-10-related T-cell-derived-inducible factor |
| Anwendung: | Bioassays |
| Reaktivität: | Human |
ab 292,00 €
IL-37 (aa 46-218) (human) (rec.) (His) Artikelnummer: CHI-AG-40A-0174-C010
IL-37 (IL-1F7, IL-1H4) is an IL-1 family member that is expressed only in certain types of human organs and cells such as heart, thymus, testis, kidney, mononuclear cells (PBMCs) and dendritic cells. IL-37 is an inhibitor of innate immunity with anti-inflammatory properties. It binds to the interleukin-18 receptor...
| Schlagworte: | IL37, IL-1X, IL-1H, IL-37, FIL1Z, IL-1H4, IL-1F7, IL-1RP1, FIL1 zeta, IL-1 zeta, Interleukin-37, Interleukin-23,... |
| Anwendung: | Bioassays |
| Reaktivität: | Human |
| MW: | ~20 kD |
ab 253,00 €
CD274 [B7-H1/PD-L1] (human):Fc (human) (rec.) (non-lytic) Artikelnummer: CHI-HF-220PDL1-C100
The extracellular domain of human CD274 [B7-H1] (aa 19-238) is fused to the N-terminus of the Fc region of a mutant human IgG1. Lyophilized from 0.2µm-filtered solution in PBS. Shows the biological function of the CD274 moiety and exerts a prolonged circulating half-life caused by the modified Fc domain. Programmed...
| Schlagworte: | B7H1, B7-H1, CD274, PD-L1, B7 homolog 1, PDCD1 ligand 1, Programmed death ligand 1, Programmed cell death 1 ligand 1 |
| Anwendung: | Bioassays |
| Reaktivität: | Human |
385,00 €
CD27 (human) (rec.) (His) Artikelnummer: CHI-HR-200CD27-C050
Human CD27 (aa 21-192) is fused at the C-terminus to a His-tag. CD27 (TNFRSF7) is a member of the TNF-receptor superfamily limited to cells of the lymphoid lineage and exists as both a dimeric glycoprotein on the cell surface and as a soluble protein in serum. As a T and B cell co-stimulatory molecule, the activity...
| Schlagworte: | T14, CD27, TNFRSF7, CD27 antigen, CD27L receptor, T-cell activation antigen CD27, Tumor necrosis factor receptor... |
| Anwendung: | Bioassays |
| Reaktivität: | Human |
330,00 €
IL-23 (mouse):Fc (human) (rec.) Artikelnummer: CHI-MF-11123-C050
The mouse IL-23 complex composed of the p40 subunit (aa 23-335) and the p19 subunit (aa 20-196) is fused through a polypeptide linker to the Fc portion of human IgG1. Lyophilized from 0.2µm-filtered solution in PBS. 0 Interleukin-23 (IL-23) is a heterodimeric cytokine composed of two disulfide-linked subunits, a p19...
| Schlagworte: | Interleukin-23, Il12b, IL-12B, CLMF p40, IL-12 subunit p40, Interleukin-12 subunit beta, Cytotoxic lymphocyte maturation... |
| Anwendung: | Bioassays |
| Reaktivität: | Mouse |
374,00 €
COVID-19 Forschung
SARS-CoV-2 Spike Protein S1 (RBD):Fc (human) (rec.) Artikelnummer: CHI-B232003-C100
Accession Number: QHD43416.1. Receptor-binding domain (RBD) of SARS-CoV-2 Spike protein S1 (aa 330-530) is fused to the N-terminus of the Fc region of human IgG1. Biological Activity: Binds to the human ACE2. Endotoxin Content: <0.001EU/µg purified protein (LAL test). SARS-CoV-2 shares 79.5% sequence identity with...
| Schlagworte: | 2019-nCoV Spike Protein S1 (RBD) |
| Anwendung: | Bindig assays |
| Reaktivität: | Sars-cov-2 |
528,00 €