Produkte von Innaxon

Innaxon

Innaxon ist ein Unternehmen in Tewkesbury in Großbritannien, das sich auf Produkte zum Thema angeborene Immunität fokussiert, wie TLR-Agonisten und niedermolekulare Inhibitoren.

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Monophosphoryl Lipid A [MPLA] from E. coli R515 (Re) TLRpure Sterile Solution
Monophosphoryl Lipid A [MPLA] from E. coli R515...

Artikelnummer: IAX-100-003-M001

Optimal concentration is dependent upon cell type, species, desired activation and analysis: 0.1-1.0 µg/ml. Does not activate any TLR other than TLR4 as tested up to 50 µg/ml in relevant cellular systems (macrophages). Activation of cells by LPS is mediated by the Toll-like receptor 4 (TLR4), a member of the highly conserved protein family of TLRs, which are specialised in...
Anwendung: TLR4 activator
Reinheit: >99.9%
Format: Purified
ab 114,00 €
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Polyinosinic-polycytidylic acid [Poly(I:C)] Endotoxin-free (sterile)
Polyinosinic-polycytidylic acid [Poly(I:C)]...

Artikelnummer: IAX-200-021-M005

Activates TLR3, MDA5/Helicard and RIG-I. Optimal working concentration depends upon target receptor accessibility, number, density, as well as cell type, and therefore needs to be determined for each application. Recommended concentration range: in vitro: 0.5-10 µg/ml, in vivo: 5mg/kg.
Anwendung: TLR3, MDA5/Helicard, RIG-I activator
Reinheit: >99.9%
Format: Purified
ab 103,00 €
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ODN 1668 (Type B) Endotoxin-free (sterile)
ODN 1668 (Type B) Endotoxin-free (sterile)

Artikelnummer: IAX-200-001-M001

Optimal concentration is dependent upon cell type, species, desired activation and analysis: in vitro 0.1-1 µM (~0.6-6.0 µg/ml), in vivo 50-250 µg in rodent animal models. Negative control: GpC ODN 1720 (Cat. No.: IAX-200-200).
Anwendung: TLR9 activator
MW: 6383 D
Reinheit: >99.9%
Format: Purified
ab 114,00 €
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Physiological Saline [Sodium Chloride 0.9%] Sterile Solution
Physiological Saline [Sodium Chloride 0.9%]...

Artikelnummer: IAX-900-003-3010

Use for the dilution of TLRpureTM LPS and solubilisation of endotoxin-free reagents (e.g. ODNs).
CAS 7647-14-5
Format: Liquid
ab 28,00 €
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IAXO-101 (CD14/TLR4 Antagonist) (synthetic)
IAXO-101 (CD14/TLR4 Antagonist) (synthetic)

Artikelnummer: IAX-600-001-M001

Described to interfere with human, rat and mouse TLR4/CD14 signaling, other species not tested. Optimal working concentration depends upon the type, purity and concentration and of TLR4 ligand, carrier protein such as LPS-binding protein (LBP), soluble and membrane-bound CD14, the presence of TLR4 co-receptors (e.g. CD36) as well as on type and time of read-out (e.g....
Anwendung: CD14/TLR4 Antagonist
CAS 1202388-64-4
MW: 810.02 D
Reinheit: >98%
Format: Purified
ab 220,00 €
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LPS (Universal) from S. abortus equi (S-form) TLRpure Sterile Solution
LPS (Universal) from S. abortus equi (S-form)...

Artikelnummer: IAX-100-009-M001

Optimal concentration is dependent upon cell type, species, desired activation and analysis: 0.01-1.0 µg/ml. Does not activate any TLR other than TLR4 as tested up to 50 µg/ml in relevant cellular systems (macrophages). Activation of cells by LPS is mediated by the Toll-like receptor 4 (TLR4). For optimal interaction with LPS, TLR4 requires association with myeloid...
Anwendung: TLR4 activator
Reinheit: >99.9%
Format: Purified
ab 87,00 €
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ODN M362 (Type C) Endotoxin-free (sterile)
ODN M362 (Type C) Endotoxin-free (sterile)

Artikelnummer: IAX-200-004-M001

Optimal concentration is dependent upon cell type, species, desired activation and analysis: in vitro 0.1-1 µM (~0.6-6.0 µg/ml), in vivo 50-250 µg in rodent animal models. Negative control: GpC ODN 2243 (Cat. No.: IAX-200-205).
Anwendung: TLR9 activator
MW: 6644 D
Reinheit: >99.9%
Format: Purified
ab 114,00 €
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ODN 2006 (Type B) Endotoxin-free (sterile)
ODN 2006 (Type B) Endotoxin-free (sterile)

Artikelnummer: IAX-200-006-M001

Optimal concentration is dependent upon cell type, species, desired activation and analysis: in vitro 0.1-1 µM (~0.7-7.0 µg/ml), in vivo 50-250 µg in rodent animal models. Negative control: GpC ODN 2137 (Cat. No.: IAX-200-206).
Anwendung: TLR9 activator
MW: 7720 D
Reinheit: >99.9%
Format: Purified
ab 114,00 €
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LPS from E. coli O111:B4 (S-form) TLRpure Sterile Solution
LPS from E. coli O111:B4 (S-form) TLRpure...

Artikelnummer: IAX-100-012-C500

Optimal concentration is dependent upon cell type, species, desired activation and analysis: 0.01-1.0 µg/ml. Does not activate any TLR other than TLR4 as tested up to 50 µg/ml in relevant cellular systems (macrophages). Activation of cells by LPS is mediated by the Toll-like receptor 4 (TLR4). For optimal interaction with LPS, TLR4 requires association with myeloid...
Anwendung: TLR4 activator
Reinheit: >99.9%
Format: Purified
ab 149,00 €
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LPS from E. coli O55:B5 (S-form) TLRpure Sterile Solution
LPS from E. coli O55:B5 (S-form) TLRpure...

Artikelnummer: IAX-100-013-M001

Optimal concentration is dependent upon cell type, species, desired activation and analysis: 0.01-1.0 µg/ml. Does not activate any TLR other than TLR4 as tested up to 50 µg/ml in relevant cellular systems (macrophages). Activation of cells by LPS is mediated by the Toll-like receptor 4 (TLR4). For optimal interaction with LPS, TLR4 requires association with myeloid...
Anwendung: TLR4 activator
Reinheit: >99.9%
Format: Purified
ab 149,00 €
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ODN 1585 (Type A) Endotoxin-free (sterile)
ODN 1585 (Type A) Endotoxin-free (sterile)

Artikelnummer: IAX-200-003-M001

Optimal concentration is dependent upon cell type, species, desired activation and analysis: in vitro 0.1-1 µM (~0.6-6.0 µg/ml), in vivo 50-250 µg in rodent animal models. Negative control: GpC ODN 2218 (Cat. No.: IAX-200-203). Unmethylated CG dinucleotides within particular sequence contexts are responsible for the immunostimulatory activity of bacterial DNA. Synthetic...
Anwendung: TLR9 activator
MW: 6643 D
Reinheit: >99.9%
Format: Purified
ab 114,00 €
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ODN 2216 (Type A) Endotoxin-free (sterile)
ODN 2216 (Type A) Endotoxin-free (sterile)

Artikelnummer: IAX-200-005-C100

3 x 1 mg. Optimal concentration is dependent upon cell type, species, desired activation and analysis: in vitro 0.1-1 µM (~0.6-6.0 µg/ml), in vivo 50-250 µg in rodent animal models. Negative control: GpC ODN 2243 (Cat. No.: IAX-200-205).
Anwendung: TLR9 activator
MW: 6644 D
Reinheit: >99.9%
Format: Purified
ab 114,00 €
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