Produkte von Innaxon

Innaxon

Innaxon ist ein Unternehmen mit Sitz in Tewkesbury, Vereinigtes Königreich, das sich auf angeborene Immunität, Toll-like Rezeptor (TLR)-Agonisten und niedermolekulare Inhibitoren konzentriert. Innaxon entwickelt und produziert definierte "Immunoceuticals" von höchster Aktivität und Reinheit für präklinische Forschungs- und Entwicklungsanwendungen für Impfstoffadjuvantien und Immuntherapie. Die einzigartigen biologischen und synthetischen TLR-Liganden von Innaxon sind gut charakterisierte und wirksame biologische Reaktionsmodifikatoren für unangemessene oder unverhältnismäßige Immunreaktionen.

Mehr Informationen unter: www.adipogen.com/innaxon

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ODN 1668 (Type B) Endotoxin-free (sterile)
ODN 1668 (Type B) Endotoxin-free (sterile)

Artikelnummer: IAX-200-001-M001

3 x 1 mg. Optimal concentration is dependent upon cell type, species, desired activation and analysis: in vitro 0.1-1 µM (~0.6-6.0 µg/ml), in vivo 50-250 µg in rodent animal models. Negative control: GpC ODN 1720 (Cat. No.: IAX-200-200).
Schlagworte: CpG ODN TLR9 Agonist: B Type (species: rodent)
Anwendung: TLR9 activator
MW: 6383 D
ab 218,00 €
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Lipodisq Control Sterile Solution
Lipodisq Control Sterile Solution

Artikelnummer: IAX-700-100-L001

A nanoparticle (11-40nm) drug delivery system comprising a discoidal phospholipid bilayer membrane stabilized by a chaperone molecule annulus. Internal properties of the phospholipid membrane support the disposition and stabilization of drug molecule candidates and preserve the native conformation of membrane...
Schlagworte: Detergent-free Nano-formulation made of Styrene-maleic Acid Lipid Particles (SMALP)
Anwendung: Nanoparticle (11-40nm) drug delivery system
286,00 €
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Curcumin (high purity) Lipodisq Sterile Solution
Curcumin (high purity) Lipodisq Sterile Solution

Artikelnummer: IAX-700-101-L001

Curcumin (high purity) Lipodisq Sterile Solution is a ready-to-use nano-formulated aqueous solution. Curcumin is a yellow pigment present in the spice turmeric (Curcuma longa) that has been associated with anti-oxidant, anti-inflammatory, anti-cancer, anti-viral and anti-bacterial activities [1-20]. However,...
Schlagworte: BRN 2306965, CCRIS 3257, NSC 32982, NSC 687842, CI 75300, 1,7-bis(4-hydroxy-3-methoxyphenyl)hepta-1,6-diene-3,5-dione,...
Anwendung: Ready-to-use nano-formulated aqueous solution
CAS 458-37-7
MW: 368.4 D
286,00 €
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Melatonin Lipodisq Sterile Solution
Melatonin Lipodisq Sterile Solution

Artikelnummer: IAX-700-102-L001

Melatonin (high purity) Lipodisq Sterile Solution is a ready-to-use nano-formulated aqueous solution. Melatonin, an evolutionarily ancient derivative of serotonin with hormonal properties, is the main neuroendocrine secretory product of the pineal gland. It regulates circadian rhythmicity and also exerts...
Schlagworte: N-Acetyl-5-methoxytryptamine, NSC 56423, NSC 113928, Regulin
Anwendung: Ready-to-use nano-formulated aqueous solution
CAS 73-31-4
MW: 232.28 D
286,00 €
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Metformin Lipodisq Sterile Solution
Metformin Lipodisq Sterile Solution

Artikelnummer: IAX-700-103-L001

Metformin Lipodisq Sterile Solution is a ready-to-use nano-formulated aqueous solution. Metformin is an antihyperglycemic agent of the biguanide class, used for the management of type II diabetes and is currently prescribed to at least 120 million people worldwide. It is an AMPK activator and a mitochondrial...
Schlagworte: 1,1-Dimethylbiguanide . HCl, NSC 91485, DMGG, LA 6023
Anwendung: Ready-to-use nano-formulated aqueous solution
CAS 1115-70-4
MW: 165.7 D
286,00 €
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Oxyresveratrol powered by LipodisqTM Sterile Solution
Oxyresveratrol powered by LipodisqTM Sterile Solution

Artikelnummer: IAX-700-104-L001

Oxyresveratrol Lipodisq Sterile Solution is a ready-to-use nano-formulated aqueous solution. Oxyresveratrol is a naturally occurring analog of resveratrol. Potent antioxidant and free-radical scavenger. Shown to have neuroprotective activity against cerebral ischemia and against traumatic injury. Apoptosis inhibitor...
Schlagworte: trans-2',3,4',5-Tetramethoxystilbene
Anwendung: Ready-to-use nano-formulated aqueous solution
CAS 29700-22-9
MW: 244,2 D
286,00 €
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Resveratrol Lipodisq Sterile Solution
Resveratrol Lipodisq Sterile Solution

Artikelnummer: IAX-700-105-L001

Resveratrol Lipodisq Sterile Solution is a ready-to-use nano-formulated aqueous solution. Potent phenolic antioxidant found in grapes and red wine. Eicosanoid synthesis and platelet aggregation inhibitor. Chemopreventive. Specific inhibitor of cyclooxygenase-1 (COX-1). Anti-inflammatory, anticancer and...
Schlagworte: trans-3,4aEUR(TM),5-Trihydroxystilbene, trans-Resveratrol, (E)-Resveratrol, 3,4aEUR(TM),5-Stilbenetriol
Anwendung: Ready-to-use nano-formulated aqueous solution
CAS 501-36-0
MW: 228,2 D
286,00 €
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Umifenovir Lipodisq Sterile Solution
Umifenovir Lipodisq Sterile Solution

Artikelnummer: IAX-700-106-L001

Umifenovir Lipodisq Sterile Solution is a ready-to-use nano-formulated aqueous solution. Umifenovir (Arbidol) is known to have broad-spectrum anti-viral activity and has earlier been approved in China and Russia for treating influenza, SARS, and Lassa viruses. It has been tested in multiple clinical studies as a...
Schlagworte: Arbidol, ARB
Anwendung: Ready-to-use nano-formulated aqueous solution
CAS 131707-23-8
MW: 513.9 D
286,00 €
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Dexamethasone Lipodisq Sterile Solution
Dexamethasone Lipodisq Sterile Solution

Artikelnummer: IAX-700-107-L001

Dexamethasone Lipodisq Sterile Solution is a ready-to-use nano-formulated aqueous solution. Dexamethasone, developed in 1957 and granted FDA approval in 1958, is a corticosteroid structurally similar to hydrocortisone and prednisolone. Dexamethasone is used to treat conditions including: endocrine, rheumatic,...
Schlagworte: MK-125, NSC 34521, 9alpha-Fluoro-16alpha-methylprednisolone,...
Anwendung: Ready-to-use nano-formulated aqueous solution
CAS 50-02-2
MW: 392,5 D
286,00 €
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Ambroxol Lipodisq Sterile Solution
Ambroxol Lipodisq Sterile Solution

Artikelnummer: IAX-700-108-L001

Ambroxol Lipodisq Sterile Solution is a ready-to-use nano-formulated aqueous solution. Ambroxol is a mucolytic agent used in the treatment of respiratory diseases. Ambroxol is a basic (pKa = 9.01) cationic drug with lipophilic properties (logP = 2.9), enabling it to act as a lysosomotropic agent. In addition,...
Schlagworte: Trans-4-[[(2-amino-3,5-dibromophenyl)methyl]amino], NA 872, Cyclohexanol
Anwendung: Ready-to-use nano-formulated aqueous solution, Expectorant, Mucolytic
CAS 23828-92-4
MW: 414.6 D
286,00 €
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ODN 2138 (Control for ODN 1826) Endotoxin-free (sterile)
ODN 2138 (Control for ODN 1826) Endotoxin-free (sterile)

Artikelnummer: IAX-200-201-C100

Negative control GpC ODN for in vivo use in rodents (50-150 µg per injection). As active compound use CpG ODN 1826 (Cat. No.: IAX-200-002). For negative control without agonistic nor antagonistic activity: Neutral-ODN (Cat. No.: IAX-200-202).
Anwendung: Negative Control for ODN 1826 (IAX-200-002)
MW: 6383 D
179,00 €
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Polyinosinic-polycytidylic acid [Poly(I:C)] Endotoxin-free (sterile)
Polyinosinic-polycytidylic acid [Poly(I:C)]...

Artikelnummer: IAX-200-021-M005

Activates TLR3, MDA5/Helicard and RIG-I. Optimal working concentration depends upon target receptor accessibility, number, density, as well as cell type, and therefore needs to be determined for each application. Recommended concentration range: in vitro: 0.5-10 µg/ml, in vivo: 5mg/kg.
Schlagworte: Polyinosinic-polycytidylic acid, potassium salt (poly (I:C))
Anwendung: TLR3, MDA5/Helicard, RIG-I activator
ab 174,00 €
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