Produkte von MediMabs

Protein function: May play a role in the integrity of hemidesmosome and the attachment of basal keratinocytes to the underlying basement membrane. [The UniProt Consortium]

Protein function: Iron sensor. Binds a 4Fe-4S cluster and functions as aconitase when cellular iron levels are high. Functions as mRNA binding protein that regulates uptake, sequestration and utilization of iron when cellular iron levels are low. Binds to iron-responsive elements (IRES) in target mRNA species when iron levels are low. Binding of a 4Fe-4S cluster precludes...

Protein function: Destroys radicals which are normally produced within the cells and which are toxic to biological systems. [The UniProt Consortium]

Protein function: Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. [The UniProt Consortium]

Protein function: Conversion of dopamine to noradrenaline. [The UniProt Consortium]

Protein function: Functions as a cell surface receptor and performs physiological functions on the surface of neurons relevant to neurite growth, neuronal adhesion and axonogenesis. Involved in cell mobility and transcription regulation through protein-protein interactions. Can promote transcription activation through binding to APBB1-KAT5 and inhibits Notch signaling...

Protein function: Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational...

Protein function: Destroys radicals which are normally produced within the cells and which are toxic to biological systems. [The UniProt Consortium]

Protein function: Destroys radicals which are normally produced within the cells and which are toxic to biological systems. [The UniProt Consortium]

Protein function: Protein kinase required for the cell cycle where it is involved in mitotic exit. A component of the fear (CDC14 early anaphase release) network which promotes CDC14 release from the nucleolus during early anaphase. Phosphorylates SCC1/MCD1 and NET1. [The UniProt Consortium]

Protein function: Protein kinase required for the cell cycle where it is involved in mitotic exit. A component of the fear (CDC14 early anaphase release) network which promotes CDC14 release from the nucleolus during early anaphase. Phosphorylates SCC1/MCD1 and NET1. [The UniProt Consortium]