Produkte von AdipoGen Life Sciences

AdipoGen

AdipoGen Life Sciences verbindet Immunologie und Metabolismus. Die AdipoGen-Zentrale befindet sich in San Diego, USA mit einem Produktionslabor in der Schweiz. Hoch qualifizierte Wissenschaftler entwickeln dort neue Produkte für den Life Science Markt in den Bereichen Krebs, Immunologie, Entzündung (Der Experte im Bereich Inflammasom-Forschung), Metabolisches Syndrom (Diabetes, Fettleibigkeit), Stammzellen und Neurodegeneration. Der Schwerpunkt liegt auf innovativen und fortschrittlichen ELISA-Kits. Zusätzlich zu den Antikörper- und Protein-Einrichtungen besitzt AdipoGen auch chemische Laboratorien für die Entwicklung neuer und innovativer Biochemikalien.

Mehr unter: www.adipogen.com

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Anti-Caspase-1 (p20) (human), clone Bally-1
Anti-Caspase-1 (p20) (human), clone Bally-1

Artikelnummer: AG-20B-0048-C100

Recognizes endogenous full-length and activated (p20 fragment) human caspase-1. Caspase-1 is activated by multiprotein complexes called Inflammasomes in response to numerous stimuli that are detected through distinct inflammasomes. NLRC4 responds to cytosolic Caspase-1 is the best-described inflammatory caspase. It...
Schlagworte: Anti-CASP1, Anti-CASP-1, Anti-ICE
Anwendung: WB
Reaktivität: Human
407,00 €
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Anti-Polyglutamate chain [Poly-E]
Anti-Polyglutamate chain [Poly-E]

Artikelnummer: AG-25B-0030-C050

Tubulin polyglutamylation stimulates spastin-mediated microtubule severing. Microtubules are key elements of the eukaryotic cytoskeleton that dynamically assemble from heterodimers of alpha- and beta-tubulin. Two different mechanisms can generate microtubule diversity: the expression of different alpha- and...
Schlagworte: Anti-Poly-E, pAb (IN105), Anti-Poly-Glu
Anwendung: WB, ICC
Reaktivität: Broad
385,00 €
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SB202190
SB202190

Artikelnummer: AG-CR1-0028-M001

Potent and cell permeable p38 MAP kinase inhibitor, Apoptosis inducer, Inhibits p38alpha and beta, but not gamma and delta isoforms, Does not inhibit ERK2 or other members of the MAP kinase family or their upstream activators, JNK activator.
Schlagworte: FHPI, 4-(4-Fluorophenyl)-2-(4-hydroxyphenyl)-5-(4-pyridyl)-1H-imidazole
Anwendung: P38 MAP kinase inhibitor
CAS 152121-30-7
MW: 331,3 D
ab 33,00 €
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COVID-19 Forschung
SARS-CoV-2 Inhibitor Screening Kit
SARS-CoV-2 Inhibitor Screening Kit

Artikelnummer: AG-48B-0001-KI01

To screen compounds that inhibit the binding of the viral protein SARS-CoV-2 Spike Protein (RBD) to its human receptor ACE2. Coronaviruses (CoVs) are enveloped non-segmented positive-sense single-stranded RNA viruses and can infect respiratory, gastrointestinal, hepatic and central nervous system of human and many...
Schlagworte: COVID-19 Inhibitor Screening Kit, 2019-nCoV Inhibitor Screening Kit, 2019-nCoV Spike Protein S1 (RBD)/ACE2 Inhibitor...
Anwendung: Compound Screening
Reaktivität: Human
715,00 €
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Latrunculin B
Latrunculin B

Artikelnummer: AG-CN2-0031-M001

Isolated from Latrunculia magnifica. Cell permeable marine toxin. Disrupts microfilament-mediated processes. Actin polymerization inhibitor in vitro and in vivo by the formation of a 1:1 complex with monomeric G-actin. Less potent than Latrunculin A. May have fewer unwanted effects than latrunculin A and may be...
Schlagworte: LAT-B, NSC 339663
Anwendung: Actin polymerization inhibitor
CAS 76343-94-7
MW: 395,5 D
ab 99,00 €
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Anti-Jagged-1 (human), clone J1G53-3, FITC conjugated
Anti-Jagged-1 (human), clone J1G53-3, FITC conjugated

Artikelnummer: AG-20A-0049F-C050

Recognizes human Jagged-1. Detects a band of about 180kDa by Western blot. Liquid. 0.2µm-filtered solution in PBS, pH 7.4. Contains no preservatives. Jagged-1 is a ligand for multiple Notch receptors and involved in the mediation of Notch signaling. It is involved in cell-fate decisions during hematopoiesis. Is...
Schlagworte: Protein Jagged-1, CD339, JAG1
Anwendung: FC
Reaktivität: Human
264,00 €
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Anti-Cardif (human), clone Adri-1
Anti-Cardif (human), clone Adri-1

Artikelnummer: AG-20B-0004-C100

Recognizes human Cardif. Liquid. In PBS containing 10% glycerol and 0.02% sodium azide. RIG-I (retinoic acid-inducible gene I, Ddx58) and MDA5 (melanoma differentiation-associated gene 5, also known as Ifih1 or Helicard) are proteins that sense viral replication intermediates, such as double-stranded RNA and...
Schlagworte: CARD Adapter Inducing Interferon-beta, IPS-1, Interferon-beta Promoter Stimulator Protein 1, MAVS, Mitochondrial Antiviral...
Anwendung: ICC, IHC, IP, WB
Reaktivität: Human
374,00 €
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Anti-FLIP, clone Dave-2
Anti-FLIP, clone Dave-2

Artikelnummer: AG-20B-0005-C100

Recognizes an epitope (aa 1-200) present in both short (FLIPS) and long (FLIPL) splice variants of human and mouse FLIP. Liquid. In PBS containing 10% glycerol and 0.02% sodium azide. FLIP is an apoptosis regulator protein which functions as a crucial link between cell survival and cell death pathways in mammalian...
Schlagworte: I-FLICE, CLARP, CASPER, Usurpin, CASH, FLAME-1
Anwendung: IP, WB
Reaktivität: Human , Mouse
429,00 €
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Anti-RIG-I, clone Alme-1
Anti-RIG-I, clone Alme-1

Artikelnummer: AG-20B-0009-C100

Recognizes human and mouse RIG-I. Liquid. In PBS containing 10% glycerol and 0.02% sodium azide. RIG-I and MDA5 are highly conserved helicases involved in the innate immune response to virus. RIG-I is a member of the DEAD-box RNA helicases and is activated by cytoplasmic dsRNA and 5'-ppp RNA produced during the...
Schlagworte: RIG-1, Retinoic Acid-inducible Gene 1 Protein, DEAD-box Protein 58, Probable ATP-dependent RNA Helicase DDX58
Anwendung: IHC, IP, WB
Reaktivität: Human , Mouse
451,00 €
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Anti-ZBP1, clone Zippy-1
Anti-ZBP1, clone Zippy-1

Artikelnummer: AG-20B-0010-C100

Recognizes human and mouse ZBP1. Liquid. In PBS containing 10% glycerol and 0.02% sodium azide. ZBP1 binds to cytoplasmic DNA and plays a role in host defense against tumors and pathogens. Highly expressed in lymphatic tissues including lymph node, leukocytes, tonsil, bone marrow and spleen.
Schlagworte: Z-DNA-binding Protein 1, Tumor Stroma and Activated Macrophage Protein DLM-1, DNA-dependent Activator of IFN-regulatory...
Anwendung: IP, WB
Reaktivität: Human , Mouse
429,00 €
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Anti-LAG-3 (human), clone 17B4), ATTO 647N conjugated
Anti-LAG-3 (human), clone 17B4), ATTO 647N conjugated

Artikelnummer: AG-20B-0012TS-T100

Recognizes human LAG-3. Liquid. In PBS containing 0.02% sodium azide. Lymphocyte activation gene 3 (LAG-3, CD223) plays an important role in negatively regulating T cell proliferation, function, and homeostasis. It is required for maximal natural and induced regulatory T cell (Treg) function. LAG-3 is closely...
Schlagworte: Lymphocyte Activation Gene-3, FDC Protein, CD223
Anwendung: FC, ICC
Reaktivität: Human
418,00 €
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Anti-NLRP3/NALP3, clone Cryo-2
Anti-NLRP3/NALP3, clone Cryo-2

Artikelnummer: AG-20B-0014-C100

Recognizes mouse and human NLRP3/NALP3. Liquid. In PBS containing 10% glycerol and 0.02% sodium azide. The inflammasome is a multiprotein complex that mediates the activation of caspase-1, which promotes, amongst others, the secretion of the proinflammatory cytokines interleukin (IL)-1beta and IL-18. Members of the...
Schlagworte: NACHT-, LRR- and PYD-containing Protein 3, NLRP3, Cryopyrin, Cold Autoinflammatory Syndrome 1 Protein
Anwendung: WB
Reaktivität: Human , Mouse
308,00 €
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