Produkte von AdipoGen Life Sciences

AdipoGen

AdipoGen Life Sciences verbindet Immunologie und Metabolismus. Die AdipoGen-Zentrale befindet sich in San Diego, USA mit einem Produktionslabor in der Schweiz. Hoch qualifizierte Wissenschaftler entwickeln dort neue Produkte für den Life Science Markt in den Bereichen Krebs, Immunologie, Entzündung (Der Experte im Bereich Inflammasom-Forschung), Metabolisches Syndrom (Diabetes, Fettleibigkeit), Stammzellen und Neurodegeneration. Der Schwerpunkt liegt auf innovativen und fortschrittlichen ELISA-Kits. Zusätzlich zu den Antikörper- und Protein-Einrichtungen besitzt AdipoGen auch chemische Laboratorien für die Entwicklung neuer und innovativer Biochemikalien.

Mehr unter: www.adipogen.com

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Anti-NLRP3/NALP3, clone Cryo-2
Anti-NLRP3/NALP3, clone Cryo-2

Artikelnummer: AG-20B-0014-C100

Recognizes mouse and human NLRP3/NALP3. Liquid. In PBS containing 10% glycerol and 0.02% sodium azide. The inflammasome is a multiprotein complex that mediates the activation of caspase-1, which promotes, amongst others, the secretion of the proinflammatory cytokines interleukin (IL)-1beta and IL-18. Members of the...
Schlagworte: NACHT-, LRR- and PYD-containing Protein 3, NLRP3, Cryopyrin, Cold Autoinflammatory Syndrome 1 Protein
Anwendung: WB
Reaktivität: Human , Mouse
308,00 €
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Anti-Polyglutamylation Modification, clone GT335
Anti-Polyglutamylation Modification, clone GT335

Artikelnummer: AG-20B-0020-C100

Recognizes the posttranslational modification (poly)glutamylation on proteins. Reacts with polyglutamylated alpha- and beta-tubulin. Liquid. In PBS containing 10% glycerol and 0.02% sodium azide. Polyglutamylation is a post-translational modification in which glutamate side chains of variable lengths are formed on...
Schlagworte: Polyglutamylated Tubulin, Glutamylated Tubulin, Postranslational Protein Glutamylation
Anwendung: ICC, IP, WB
Reaktivität: All
418,00 €
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Anti-Caspase-1 (p20) (mouse), clone Casper-1
Anti-Caspase-1 (p20) (mouse), clone Casper-1

Artikelnummer: AG-20B-0042-C100

Recognizes endogenous full-length and activated (p20 fragement) mouse caspase-1. Caspase-1 is the best-described inflammatory caspase. It processes the cytokines interleukin-1beta (IL-1beta) and IL-18 and induces pyroptotic cell death. Caspase-1 is activated by multiprotein complexes called Inflammasomes in response...
Schlagworte: Anti-CASP1, Anti-CASP-1, Anti-ICE, EC=3.4.22.36
Anwendung: WB
Reaktivität: Mouse
407,00 €
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Anti-Caspase-1 (p20) (human), clone Bally-1
Anti-Caspase-1 (p20) (human), clone Bally-1

Artikelnummer: AG-20B-0048-C100

Recognizes endogenous full-length and activated (p20 fragment) human caspase-1. Caspase-1 is activated by multiprotein complexes called Inflammasomes in response to numerous stimuli that are detected through distinct inflammasomes. NLRC4 responds to cytosolic Caspase-1 is the best-described inflammatory caspase. It...
Schlagworte: Anti-CASP1, Anti-CASP-1, Anti-ICE
Anwendung: WB
Reaktivität: Human
407,00 €
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Anti-Asc (AL177)
Anti-Asc (AL177)

Artikelnummer: AG-25B-0006-C100

Recognizes human and mouse Asc. Liquid. In PBS containing 10% glycerol and 0.02% sodium azide. Asc promotes caspase-mediated apoptosis. This proapoptotic activity is mediated predominantly through the activation of caspase-9. It is a component of the inflammasome, a protein complex which also includes NALP2, CARD8...
Schlagworte: Pycard, Target of Methylation-induced Silencing 1, TMS1, Caspase Recruitment Domain-containing Protein 5,...
Anwendung: ICC, IHC, IP, WB
Reaktivität: Human , Mouse
440,00 €
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BAFF, Soluble (human) ELISA Kit (hypersensitive)
BAFF, Soluble (human) ELISA Kit (hypersensitive)

Artikelnummer: AG-45B-0001-KI01

Detection Type: Colorimetric. Assay Type: Sandwich. Sample Type: Cell Culture Supernatant , Plasma , Serum. Sensitivity: 8pg/ml. Range: 0.0156 to 1ng/ml. BAFF (B cell-activating factor, BLyS, B lymphocyte stimulator, TNFSF13B, TALL-1, CD257), belonging to the TNF family, is a master regulator of peripheral B cell...
Schlagworte: BlyS, B Cell Activating Factor
Anwendung: ELISA
Reaktivität: Human
616,00 €
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Anti-RIG-I, clone Alme-1
Anti-RIG-I, clone Alme-1

Artikelnummer: AG-20B-0009-C100

Recognizes human and mouse RIG-I. Liquid. In PBS containing 10% glycerol and 0.02% sodium azide. RIG-I and MDA5 are highly conserved helicases involved in the innate immune response to virus. RIG-I is a member of the DEAD-box RNA helicases and is activated by cytoplasmic dsRNA and 5'-ppp RNA produced during the...
Schlagworte: RIG-1, Retinoic Acid-inducible Gene 1 Protein, DEAD-box Protein 58, Probable ATP-dependent RNA Helicase DDX58
Anwendung: IHC, IP, WB
Reaktivität: Human , Mouse
451,00 €
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Anti-FLIP, clone Dave-2
Anti-FLIP, clone Dave-2

Artikelnummer: AG-20B-0005-C100

Recognizes an epitope (aa 1-200) present in both short (FLIPS) and long (FLIPL) splice variants of human and mouse FLIP. Liquid. In PBS containing 10% glycerol and 0.02% sodium azide. FLIP is an apoptosis regulator protein which functions as a crucial link between cell survival and cell death pathways in mammalian...
Schlagworte: I-FLICE, CLARP, CASPER, Usurpin, CASH, FLAME-1
Anwendung: IP, WB
Reaktivität: Human , Mouse
429,00 €
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Anti-CD40 (mouse), clone FGK45) (preservative free)
Anti-CD40 (mouse), clone FGK45) (preservative free)

Artikelnummer: AG-20B-0036PF-C500

Recognizes mouse CD40. Liquid. In PBS. CD40 belongs to the TNF-receptor superfamily and is essential in mediating a broad variety of immune and inflammatory responses including T cell-dependent immunoglobulin class switching, memory B cell development, and germinal center formation. The interaction of CD40-CD40L is...
Schlagworte: Tumor Necrosis Factor Receptor Superfamily Member 5, CD40L Receptor
Anwendung: FC, Bioassays
Reaktivität: Mouse
ab 132,00 €
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Opaganib
Opaganib

Artikelnummer: AG-CR1-3749-M005

Opaganib is a selective inhibitor of sphingosine kinase 2 (SPHK2, Ki = 9.8 µM), a lipid kinase that catalyzes formation of the lipid signaling molecule sphingosine 1-phosphate (S1P). S1P promotes cancer growth, and proliferation and pathological inflammation, including TNF-alpha signaling and other inflammatory...
Schlagworte: 3-(4-Chlorophenyl)-adamantane-1-carboxylic acid (pyridin-4-ylmethyl)amide, ABC294640, Yeliva
Anwendung: SPHK2 inhibitor
CAS 915385-81-8
MW: 380.9 D
ab 99,00 €
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Rilpivirine
Rilpivirine

Artikelnummer: AG-CR1-3750-M005

Rilpivirine is a non-nucleoside reverse transcriptase inhibitor (NNRTI) that inhibits growth of wild-type HIV with an EC50 value of 0.51nM. It is active against NNRTI-resistant HIV strains with EC50 values less than 1nM for L100I, K103N, V106A, G190A and G190S mutants in vitro. Rilpivirine also reduces growth of...
Schlagworte: R278474, TMC278, DB08865
Anwendung: Antiviral, Reverse transcriptase inhibitor
CAS 500287-72-9
MW: 366.4 D
ab 55,00 €
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Efavirenz
Efavirenz

Artikelnummer: AG-CR1-3751-M010

Efavirenz is a non-nucleoside reverse transcriptase inhibitor (NNRTI) that exhibits antiviral and anticancer activities. Efavirenz binds to wild-type and mutant HIV-1 RTs (Ki= 2.93nM and 3.85-56.5nM, respectively). It inhibits wild-type and mutant HIV-1 viral replication in MT-4 human T lymphoid cells (IC95s =...
Schlagworte: DMP 266, EFV, L-743,726
Anwendung: Antiviral, Reverse transcriptase inhibitor
CAS 154598-52-4
MW: 315.7 D
ab 44,00 €
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