Produkte von Bethyl
Auf der texanischen Bethyl-Ranch werden traditionell beste polyklonale Antikörper für die klinische und diagnostische Forschung hergestellt. Bethyls Netzwerk mit namhaften Wissenschaftlern identifiziert fortlaufend neue Targets für die zellbiologische Forschung. Daraus entsteht ein Antikörperprogramm, das vergleichbaren Anbietern immer einen Schritt voraus ist. Bethyl ist einzigartig in ihrer vollständigen Kontrolle aller Schritte der Antikörperproduktion. Von den veterinären Einrichtungen, über die Entwicklung, Produktion und Validierung in den Laboren konzentriert sich das Team von Bethyl darauf, qualitativ hochwertige Produkte zu liefern. Diese Fokussierung auf Qualität bei jedem einzelnen Schritt und die Integration aller Prozessstufen bedeutet, dass Wissenschaftler sich auf Bethyl-Antikörper verlassen können.
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Anti-ASH2
Artikelnummer: A300-489A
Protein function: Component of the Set1/Ash2 histone methyltransferase (HMT) complex, a complex that specifically methylates 'Lys-4' of histone H3, but not if the neighboring 'Lys-9' residue is already methylated. As part of the MLL1/MLL complex it is involved in methylation and dimethylation at 'Lys-4' of histone H3. May function as a transcriptional regulator. May play a...
| Anwendung: | WB, IP, IHC, ChIP, ChIP-chip |
| Antikörper-Typ: | Polyclonal |
| Wirt: | Rabbit |
| Reaktivität: | Human |
| Format: | Antigen Affinity Purified |
430,00 €
Anti-RBM9 (IHC)
Artikelnummer: IHC-00199
Protein function: RNA-binding protein that regulates alternative splicing events by binding to 5'-UGCAUGU-3' elements. Prevents binding of U2AF2 to the 3'-splice site. Regulates alternative splicing of tissue-specific exons and of differentially spliced exons during erythropoiesis. RNA-binding protein that seems to act as a coregulatory factor of ER-alpha. [The UniProt...
| Anwendung: | IHC |
| Antikörper-Typ: | Polyclonal |
| Wirt: | Rabbit |
| Reaktivität: | Human, Mouse |
| Format: | Antigen Affinity Purified |
ab 125,00 €
Anti-SMARCC2/BAF170 (IHC)
Artikelnummer: IHC-00213
Protein function: Involved in transcriptional activation and repression of select genes by chromatin remodeling (alteration of DNA-nucleosome topology). Can stimulate the ATPase activity of the catalytic subunit of these complexes. May be required for CoREST dependent repression of neuronal specific gene promoters in non-neuronal cells. Belongs to the neural...
| Anwendung: | IHC |
| Antikörper-Typ: | Polyclonal |
| Wirt: | Rabbit |
| Reaktivität: | Human, Mouse |
| Format: | Antigen Affinity Purified |
ab 125,00 €
Anti-MafA (IHC)
Artikelnummer: IHC-00352
Protein function: Acts as a transcriptional factor. Specifically binds the insulin enhancer element RIPE3b. Cooperates synergistically with NEUROD1 and PDX1. Phosphorylation by GSK3 increases its transcriptional activity and is required for its oncogenic activity. Regulates the insulin gene transcription. Involved either as an oncogene or as a tumor suppressor, depending on...
| Anwendung: | IHC |
| Antikörper-Typ: | Polyclonal |
| Wirt: | Rabbit |
| Reaktivität: | Mouse |
| Format: | Antigen Affinity Purified |
ab 125,00 €
Anti-Ki-67 (IHC)
Artikelnummer: IHC-00375
Protein function: Required to maintain individual mitotic chromosomes dispersed in the cytoplasm following nuclear envelope disassembly (PubMed:27362226). Associates with the surface of the mitotic chromosome, the perichromosomal layer, and covers a substantial fraction of the chromosome surface (PubMed:27362226). Prevents chromosomes from collapsing into a single chromatin...
| Anwendung: | IHC |
| Antikörper-Typ: | Polyclonal |
| Wirt: | Rabbit |
| Reaktivität: | Mouse |
| Format: | Antigen Affinity Purified |
ab 125,00 €
Anti-phospho-EZH2 (Ser21) (IHC)
Artikelnummer: IHC-00388
Protein function: Polycomb group (PcG) protein. Catalytic subunit of the PRC2/EED-EZH2 complex, which methylates 'Lys-9' (H3K9me) and 'Lys- 27' (H3K27me) of histone H3, leading to transcriptional repression of the affected target gene. Able to mono-, di- and trimethylate 'Lys-27' of histone H3 to form H3K27me1, H3K27me2 and H3K27me3, respectively. Compared to EZH2-containing...
| Anwendung: | IHC |
| Antikörper-Typ: | Polyclonal |
| Wirt: | Rabbit |
| Reaktivität: | Human, Mouse |
| Format: | Antigen Affinity Purified |
ab 125,00 €
Anti-CASC5 (IHC)
Artikelnummer: IHC-00500
Protein function: Performs two crucial functions during mitosis: it is essential for spindle-assembly checkpoint signaling and for correct chromosome alignment. Required for attachment of the kinetochores to the spindle microtubules. Directly links BUB1 and BUB1B to kinetochores. Part of the MIS12 complex, which may be fundamental for kinetochore formation and proper...
| Anwendung: | IHC |
| Antikörper-Typ: | Polyclonal |
| Wirt: | Rabbit |
| Reaktivität: | Human |
| Format: | Antigen Affinity Purified |
ab 125,00 €
Anti-YAP1 (IHC)
Artikelnummer: IHC-00665
Protein function: Transcriptional regulator which can act both as a coactivator and a corepressor and is the critical downstream regulatory target in the Hippo signaling pathway that plays a pivotal role in organ size control and tumor suppression by restricting proliferation and promoting apoptosis (PubMed:17974916, PubMed:18280240, PubMed:18579750, PubMed:21364637). The...
| Anwendung: | IHC, IHC-IF |
| Antikörper-Typ: | Polyclonal |
| Wirt: | Rabbit |
| Reaktivität: | Human |
| Format: | Antigen Affinity Purified |
ab 125,00 €
ReliaBLOT(R) IP/Western Blot Reagents
Artikelnummer: WB120
The ReliaBLOT IP/Western Blot Reagents and Procedures (patent pending) provide an improved method for the detection of immunoprecipitated proteins assayed via Western Blot.
| Anwendung: | WB, IP |
| Format: | Membrane Based |
355,00 €
ReliaBLOT(R) IP/Western Blot Reagents
Artikelnummer: WB120T
The ReliaBLOT IP/Western Blot Reagents and Procedures (patent pending) provide an improved method for the detection of immunoprecipitated proteins assayed via Western Blot.
| Anwendung: | WB, IP |
| Format: | Membrane Based |
139,00 €
Anti-ECS (DDDDK)
Artikelnummer: A190-101A
| Anwendung: | WB, IP, ICC, ELISA |
| Antikörper-Typ: | Polyclonal |
| Wirt: | Goat |
| Format: | Antigen Affinity Purified |
241,00 €
Anti-c-myc
Artikelnummer: A190-104A
Protein function: Transcription factor that binds DNA in a non-specific manner, yet also specifically recognizes the core sequence 5'- CAC[GA]TG-3'. Activates the transcription of growth-related genes. [The UniProt Consortium]
| Anwendung: | WB, IP, ICC, ELISA |
| Antikörper-Typ: | Polyclonal |
| Wirt: | Goat |
| Format: | Antigen Affinity Purified |
241,00 €
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