Produkte von Bethyl Laboratories

Bethyl

Auf der texanischen Ranch von Bethyl Labs werden beste polyklonale Antikörper für die klinische und diagnostische Forschung hergestellt. Bethyls Netzwerk mit namhaften Wissenschaftlern identifiziert fortlaufend neue Targets für die zellbiologische Forschung. Daraus entsteht ein Antikörperprogramm, das vergleichbaren Anbietern immer einen Schritt voraus ist. Bethyl Laboratories sind einzigartig in ihrer vollständigen Kontrolle aller Schritte der Antikörperproduktion. Von den veterinären Einrichtungen, über die Entwicklung, Produktion und Validierung in den Laboren konzentriert sich das Team von Bethyl darauf, qualitativ hochwertige Produkte zu liefern. Diese Fokussierung auf Qualität bei jedem einzelnen Schritt und die Integration aller Prozessstufen bedeutet, dass Wissenschaftler sich auf Bethyl-Antikörper verlassen können.

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Anti-BRCA1
Anti-BRCA1

Artikelnummer: A300-000A

Protein function: E3 ubiquitin-protein ligase that specifically mediates the formation of 'Lys-6'-linked polyubiquitin chains and plays a central role in DNA repair by facilitating cellular responses to DNA damage. It is unclear whether it also mediates the formation of other types of polyubiquitin chains. The E3...
Schlagworte: Anti-BRCA1, Anti-RNF53, Anti-RING finger protein 53, Anti-RING-type E3 ubiquitin transferase BRCA1, Anti-Breast cancer...
Anwendung: WB, IP
Reaktivität: Human
443,00 €
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Anti-phospho-RPA32 (Ser4/Ser8)
Anti-phospho-RPA32 (Ser4/Ser8)

Artikelnummer: A300-245A

Protein function: As part of the heterotrimeric replication protein A complex (RPA/RP-A), binds and stabilizes single-stranded DNA intermediates, that form during DNA replication or upon DNA stress. It prevents their reannealing and in parallel, recruits and activates different proteins and complexes involved in DNA...
Schlagworte: Anti-phospho-RPA2, Anti-phospho-REPA2, Anti-phospho-RP-A p34, Anti-phospho-RP-A p32, Anti-phospho-RF-A protein 2,...
Anwendung: WB, IP, IHC, ICC/IF
Reaktivität: Human, Mouse
ab 125,00 €
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Anti-phospho-RPA32 (Ser33)
Anti-phospho-RPA32 (Ser33)

Artikelnummer: A300-246A-M

Protein function: As part of the heterotrimeric replication protein A complex (RPA/RP-A), binds and stabilizes single-stranded DNA intermediates, that form during DNA replication or upon DNA stress. It prevents their reannealing and in parallel, recruits and activates different proteins and complexes involved in DNA...
Schlagworte: Anti-phospho-RPA2, Anti-phospho-REPA2, Anti-phospho-RP-A p34, Anti-phospho-RP-A p32, Anti-phospho-RF-A protein 2,...
Anwendung: WB, IHC
Reaktivität: Human
ab 125,00 €
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Anti-BARD1
Anti-BARD1

Artikelnummer: A300-263A

Protein function: E3 ubiquitin-protein ligase. The BRCA1-BARD1 heterodimer specifically mediates the formation of 'Lys-6'-linked polyubiquitin chains and coordinates a diverse range of cellular pathways such as DNA damage repair, ubiquitination and transcriptional regulation to maintain genomic stability. Plays a...
Schlagworte: Anti-BARD1, Anti-BARD-1, Anti-BRCA1-associated RING domain protein 1, Anti-RING-type E3 ubiquitin transferase BARD1
Anwendung: WB, IP
Reaktivität: Human
ab 125,00 €
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Anti-ASH2
Anti-ASH2

Artikelnummer: A300-489A

Protein function: Component of the Set1/Ash2 histone methyltransferase (HMT) complex, a complex that specifically methylates 'Lys-4' of histone H3, but not if the neighboring 'Lys-9' residue is already methylated. As part of the MLL1/MLL complex it is involved in methylation and dimethylation at 'Lys-4' of histone...
Schlagworte: Anti-ASH2L, Anti-ASH2L1, Anti-ASH2-like protein, Anti-Set1/Ash2 histone methyltransferase complex subunit ASH2
Anwendung: WB, IP, IHC, ChIP, ChIP-chip
Reaktivität: Human
443,00 €
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Anti-KIAA0310
Anti-KIAA0310

Artikelnummer: A300-648A

Protein function: Defines endoplasmic reticulum exit sites (ERES) and is required for secretory cargo traffic from the endoplasmic reticulum to the Golgi apparatus. SAR1A-GTP-dependent assembly of SEC16A on the ER membrane forms an organized scaffold defining an ERES. Required for normal transitional endoplasmic...
Schlagworte: Anti-SEC16A, Anti-KIAA0310, Anti-SEC16 homolog A, Anti-Protein transport protein Sec16A
Anwendung: WB, IP
Reaktivität: Human
ab 125,00 €
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Anti-MED12
Anti-MED12

Artikelnummer: A300-774A

Protein function: Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is...
Schlagworte: Anti-MED12, Anti-ARC240, Anti-Trap230, Anti-CAG repeat protein 45, Anti-OPA-containing protein, Anti-Mediator complex...
Anwendung: WB, IP, IHC
Reaktivität: Human, Mouse
ab 125,00 €
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Anti-XRN2
Anti-XRN2

Artikelnummer: A301-103A

Protein function: Possesses 5'->3' exoribonuclease activity. May promote the termination of transcription by RNA polymerase II. During transcription termination, cleavage at the polyadenylation site liberates a 5' fragment which is subsequently processed to form the mature mRNA and a 3' fragment which remains...
Schlagworte: Anti-XRN2, EC=3.1.13.-, Anti-DHP protein, Anti-DHM1-like protein, Anti-5'-3' exoribonuclease 2
Anwendung: WB, IP, IHC
Reaktivität: Human, Mouse
ab 125,00 €
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Anti-RNF31
Anti-RNF31

Artikelnummer: A303-560A-M

Protein function: E3 ubiquitin-protein ligase component of the LUBAC complex which conjugates linear ('Met-1'-linked) polyubiquitin chains to substrates and plays a key role in NF-kappa-B activation and regulation of inflammation (PubMed:17006537, PubMed:19136968, PubMed:20005846, PubMed:21455173, PubMed:21455180,...
Schlagworte: Anti-HOIP, EC=2.3.2.27, Anti-RING finger protein 31, Anti-HOIL-1-interacting protein, Anti-E3 ubiquitin-protein ligase...
Anwendung: WB, IP
Reaktivität: Human, Mouse
ab 125,00 €
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Anti-BRD4 Recombinant Monoclonal
Anti-BRD4 Recombinant Monoclonal

Artikelnummer: A700-004

Protein function: Chromatin reader protein that recognizes and binds acetylated histones and plays a key role in transmission of epigenetic memory across cell divisions and transcription regulation. Remains associated with acetylated chromatin throughout the entire cell cycle and provides epigenetic memory for...
Schlagworte: Anti-BRD4, Anti-HUNK1, Anti-Protein HUNK1, Anti-Bromodomain-containing protein 4
Anwendung: WB, IP, IHC, ICC/IF, ChIP-Seq
Reaktivität: Human
ab 125,00 €
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Anti-RBM9 (IHC)
Anti-RBM9 (IHC)

Artikelnummer: IHC-00199

Protein function: RNA-binding protein that regulates alternative splicing events by binding to 5'-UGCAUGU-3' elements. Prevents binding of U2AF2 to the 3'-splice site. Regulates alternative splicing of tissue-specific exons and of differentially spliced exons during erythropoiesis. RNA-binding protein that seems to...
Schlagworte: Anti-FOX2, Anti-RBFOX2, Anti-Fox-1 homolog B, Anti-RNA-binding protein 9, Anti-RNA-binding motif protein 9, Anti-RNA...
Anwendung: IHC
Reaktivität: Human, Mouse
ab 125,00 €
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Anti-SMARCC2/BAF170 (IHC)
Anti-SMARCC2/BAF170 (IHC)

Artikelnummer: IHC-00213

Protein function: Involved in transcriptional activation and repression of select genes by chromatin remodeling (alteration of DNA-nucleosome topology). Can stimulate the ATPase activity of the catalytic subunit of these complexes. May be required for CoREST dependent repression of neuronal specific gene promoters...
Schlagworte: Anti-BAF170, Anti-SMARCC2, Anti-BRG1-associated factor 170, Anti-SWI/SNF complex 170 kDa subunit, Anti-SWI/SNF complex...
Anwendung: IHC
Reaktivität: Human, Mouse
ab 125,00 €
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