Produkte von Bethyl
Auf der texanischen Bethyl-Ranch werden traditionell beste polyklonale Antikörper für die klinische und diagnostische Forschung hergestellt. Bethyls Netzwerk mit namhaften Wissenschaftlern identifiziert fortlaufend neue Targets für die zellbiologische Forschung. Daraus entsteht ein Antikörperprogramm, das vergleichbaren Anbietern immer einen Schritt voraus ist. Bethyl ist einzigartig in ihrer vollständigen Kontrolle aller Schritte der Antikörperproduktion. Von den veterinären Einrichtungen, über die Entwicklung, Produktion und Validierung in den Laboren konzentriert sich das Team von Bethyl darauf, qualitativ hochwertige Produkte zu liefern. Diese Fokussierung auf Qualität bei jedem einzelnen Schritt und die Integration aller Prozessstufen bedeutet, dass Wissenschaftler sich auf Bethyl-Antikörper verlassen können.
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Anti-ECS (DDDDK)
Artikelnummer: A190-101A
| Anwendung: | WB, IP, ICC, ELISA |
| Antikörper-Typ: | Polyclonal |
| Wirt: | Goat |
| Format: | Antigen Affinity Purified |
241,00 €
Anti-c-myc
Artikelnummer: A190-105B
Protein function: Transcription factor that binds DNA in a non-specific manner, yet also specifically recognizes the core sequence 5'- CAC[GA]TG-3'. Activates the transcription of growth-related genes. [The UniProt Consortium]
| Anwendung: | WB, ELISA |
| Antikörper-Typ: | Polyclonal |
| Wirt: | Rabbit |
| Format: | Antigen Affinity Purified |
270,00 €
Anti-USP7
Artikelnummer: A300-033A
Protein function: Hydrolase that deubiquitinates target proteins such as FOXO4, p53/TP53, MDM2, ERCC6, DNMT1, UHRF1, PTEN and DAXX (PubMed:11923872, PubMed:15053880, PubMed:16964248, PubMed:18716620, PubMed:25283148). Together with DAXX, prevents MDM2 self-ubiquitination and enhances the E3 ligase activity of MDM2 towards p53/TP53, thereby promoting p53/TP53 ubiquitination...
| Anwendung: | WB, IP, IHC |
| Antikörper-Typ: | Polyclonal |
| Wirt: | Rabbit |
| Reaktivität: | Human, Mouse |
| Format: | Antigen Affinity Purified |
ab 125,00 €
Anti-NF1
Artikelnummer: A300-140A-M
Protein function: Stimulates the GTPase activity of Ras. NF1 shows greater affinity for Ras GAP, but lower specific activity. May be a regulator of Ras activity. [The UniProt Consortium]
| Anwendung: | WB, IP |
| Antikörper-Typ: | Polyclonal |
| Wirt: | Rabbit |
| Reaktivität: | Human, Mouse |
| Format: | Antigen Affinity Purified |
ab 125,00 €
Anti-phospho-RPA32 (Ser33)
Artikelnummer: A300-246A
Protein function: As part of the heterotrimeric replication protein A complex (RPA/RP-A), binds and stabilizes single-stranded DNA intermediates, that form during DNA replication or upon DNA stress. It prevents their reannealing and in parallel, recruits and activates different proteins and complexes involved in DNA metabolism. Thereby, it plays an essential role both in DNA...
| Anwendung: | WB |
| Antikörper-Typ: | Polyclonal |
| Wirt: | Rabbit |
| Reaktivität: | Human |
| Format: | Antigen Affinity Purified |
ab 125,00 €
Anti-p14ARF
Artikelnummer: A300-342A
Protein function: Acts as a negative regulator of the proliferation of normal cells by interacting strongly with CDK4 and CDK6. This inhibits their ability to interact with cyclins D and to phosphorylate the retinoblastoma protein. [The UniProt Consortium]
| Anwendung: | WB, IHC |
| Antikörper-Typ: | Polyclonal |
| Wirt: | Rabbit |
| Reaktivität: | Human |
| Format: | Antigen Affinity Purified |
ab 125,00 €
Anti-DDX3
Artikelnummer: A300-474A
Protein function: Multifunctional ATP-dependent RNA helicase. The ATPase activity can be stimulated by various ribo- and deoxynucleic acids indicative for a relaxed substrate specificity. In vitro can unwind partially double-stranded DNA with a preference for 5'- single-stranded DNA overhangs. Is involved in several steps of gene expression, such as transcription, mRNA...
| Anwendung: | WB, IP, IHC |
| Antikörper-Typ: | Polyclonal |
| Wirt: | Rabbit |
| Reaktivität: | Human, Mouse |
| Format: | Antigen Affinity Purified |
ab 125,00 €
Anti-LATS1/LATS2
Artikelnummer: A300-479A-M
Protein function: Negative regulator of YAP1 in the Hippo signaling pathway that plays a pivotal role in organ size control and tumor suppression by restricting proliferation and promoting apoptosis. The core of this pathway is composed of a kinase cascade wherein STK3/MST2 and STK4/MST1, in complex with its regulatory protein SAV1, phosphorylates and activates LATS1/2 in...
| Anwendung: | WB, IP |
| Antikörper-Typ: | Polyclonal |
| Wirt: | Rabbit |
| Reaktivität: | Human, Mouse |
| Format: | Antigen Affinity Purified |
ab 125,00 €
Anti-ASH2
Artikelnummer: A300-489A
Protein function: Component of the Set1/Ash2 histone methyltransferase (HMT) complex, a complex that specifically methylates 'Lys-4' of histone H3, but not if the neighboring 'Lys-9' residue is already methylated. As part of the MLL1/MLL complex it is involved in methylation and dimethylation at 'Lys-4' of histone H3. May function as a transcriptional regulator. May play a...
| Anwendung: | WB, IP, IHC, ChIP, ChIP-chip |
| Antikörper-Typ: | Polyclonal |
| Wirt: | Rabbit |
| Reaktivität: | Human |
| Format: | Antigen Affinity Purified |
430,00 €
Anti-NONO
Artikelnummer: A300-587A
Protein function: DNA- and RNA binding protein, involved in several nuclear processes. Binds the conventional octamer sequence in double-stranded DNA. Also binds single-stranded DNA and RNA at a site independent of the duplex site. Involved in pre-mRNA splicing, probably as a heterodimer with SFPQ. Interacts with U5 snRNA, probably by binding to a purine-rich sequence...
| Anwendung: | WB, IP, IHC |
| Antikörper-Typ: | Polyclonal |
| Wirt: | Rabbit |
| Reaktivität: | Human, Mouse, Rat |
| Format: | Antigen Affinity Purified |
ab 125,00 €
Anti-phospho-RNA Polymerase II (Ser2)
Artikelnummer: A300-654A-T
Protein function: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Largest and catalytic component of RNA polymerase II which synthesizes mRNA precursors and many functional non-coding RNAs. Forms the polymerase active center together with the second largest subunit. Pol II is the central...
| Anwendung: | WB, IP, IHC |
| Antikörper-Typ: | Polyclonal |
| Wirt: | Rabbit |
| Reaktivität: | Human, Mouse |
| Format: | Antigen Affinity Purified |
ab 125,00 €
Anti-phospho-KAP-1 (Ser824)
Artikelnummer: A300-767A
Protein function: Nuclear corepressor for KRAB domain-containing zinc finger proteins (KRAB-ZFPs). Mediates gene silencing by recruiting CHD3, a subunit of the nucleosome remodeling and deacetylation (NuRD) complex, and SETDB1 (which specifically methylates histone H3 at 'Lys-9' (H3K9me)) to the promoter regions of KRAB target genes. Enhances transcriptional repression by...
| Anwendung: | WB, IP, IHC, ICC, ICC/IF |
| Antikörper-Typ: | Polyclonal |
| Wirt: | Rabbit |
| Reaktivität: | Human, Mouse |
| Format: | Antigen Affinity Purified |
ab 125,00 €
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