Produkte von Bethyl Laboratories
Auf der texanischen Ranch von Bethyl Labs werden beste polyklonale Antikörper für die klinische und diagnostische Forschung hergestellt. Bethyls Netzwerk mit namhaften Wissenschaftlern identifiziert fortlaufend neue Targets für die zellbiologische Forschung. Daraus entsteht ein Antikörperprogramm, das vergleichbaren Anbietern immer einen Schritt voraus ist. Bethyl Laboratories sind einzigartig in ihrer vollständigen Kontrolle aller Schritte der Antikörperproduktion. Von den veterinären Einrichtungen, über die Entwicklung, Produktion und Validierung in den Laboren konzentriert sich das Team von Bethyl darauf, qualitativ hochwertige Produkte zu liefern. Diese Fokussierung auf Qualität bei jedem einzelnen Schritt und die Integration aller Prozessstufen bedeutet, dass Wissenschaftler sich auf Bethyl-Antikörper verlassen können.
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Anti-ASH2 Artikelnummer: A300-489A
Protein function: Component of the Set1/Ash2 histone methyltransferase (HMT) complex, a complex that specifically methylates 'Lys-4' of histone H3, but not if the neighboring 'Lys-9' residue is already methylated. As part of the MLL1/MLL complex it is involved in methylation and dimethylation at 'Lys-4' of histone...
| Schlagworte: | Anti-ASH2L, Anti-ASH2L1, Anti-ASH2-like protein, Anti-Set1/Ash2 histone methyltransferase complex subunit ASH2 |
| Anwendung: | WB, IP, IHC, ChIP, ChIP-chip |
| Reaktivität: | Human |
443,00 €
Anti-RBM9 (IHC) Artikelnummer: IHC-00199
Protein function: RNA-binding protein that regulates alternative splicing events by binding to 5'-UGCAUGU-3' elements. Prevents binding of U2AF2 to the 3'-splice site. Regulates alternative splicing of tissue-specific exons and of differentially spliced exons during erythropoiesis. RNA-binding protein that seems to...
| Schlagworte: | Anti-FOX2, Anti-RBFOX2, Anti-Fox-1 homolog B, Anti-RNA-binding protein 9, Anti-RNA-binding motif protein 9, Anti-RNA... |
| Anwendung: | IHC |
| Reaktivität: | Human, Mouse |
ab 125,00 €
Anti-SMARCC2/BAF170 (IHC) Artikelnummer: IHC-00213
Protein function: Involved in transcriptional activation and repression of select genes by chromatin remodeling (alteration of DNA-nucleosome topology). Can stimulate the ATPase activity of the catalytic subunit of these complexes. May be required for CoREST dependent repression of neuronal specific gene promoters...
| Schlagworte: | Anti-BAF170, Anti-SMARCC2, Anti-BRG1-associated factor 170, Anti-SWI/SNF complex 170 kDa subunit, Anti-SWI/SNF complex... |
| Anwendung: | IHC |
| Reaktivität: | Human, Mouse |
ab 125,00 €
Anti-MafA (IHC) Artikelnummer: IHC-00352
Protein function: Acts as a transcriptional factor. Specifically binds the insulin enhancer element RIPE3b. Cooperates synergistically with NEUROD1 and PDX1. Phosphorylation by GSK3 increases its transcriptional activity and is required for its oncogenic activity. Regulates the insulin gene transcription. Involved...
| Schlagworte: | Anti-Mafa, Anti-Transcription factor MafA, Anti-Pancreatic beta-cell-specific transcriptional activator, Anti-V-maf... |
| Anwendung: | IHC |
| Reaktivität: | Mouse |
ab 125,00 €
Anti-Ki-67 (IHC) Artikelnummer: IHC-00375
Protein function: Required to maintain individual mitotic chromosomes dispersed in the cytoplasm following nuclear envelope disassembly (PubMed:27362226). Associates with the surface of the mitotic chromosome, the perichromosomal layer, and covers a substantial fraction of the chromosome surface (PubMed:27362226)....
| Schlagworte: | Anti-Antigen Ki67 homolog, Anti-Antigen KI-67 homolog, Anti-Proliferation marker protein Ki-67, Anti-Antigen identified by... |
| Anwendung: | IHC |
| Reaktivität: | Mouse |
ab 125,00 €
Anti-phospho-EZH2 (Ser21) (IHC) Artikelnummer: IHC-00388
Protein function: Polycomb group (PcG) protein. Catalytic subunit of the PRC2/EED-EZH2 complex, which methylates 'Lys-9' (H3K9me) and 'Lys- 27' (H3K27me) of histone H3, leading to transcriptional repression of the affected target gene. Able to mono-, di- and trimethylate 'Lys-27' of histone H3 to form H3K27me1,...
| Schlagworte: | Anti-phospho-EZH2, Anti-phospho-KMT6, Anti-phospho-ENX-1, EC=2.1.1.43, Anti-phospho-Enhancer of zeste homolog 2,... |
| Anwendung: | IHC |
| Reaktivität: | Human, Mouse |
ab 125,00 €
Anti-ZEB1 (IHC) Artikelnummer: IHC-00419
Protein function: Acts as a transcriptional repressor. Inhibits interleukin-2 (IL-2) gene expression. Enhances or represses the promoter activity of the ATP1A1 gene depending on the quantity of cDNA and on the cell type. Represses E-cadherin promoter and induces an epithelial-mesenchymal transition (EMT) by...
| Schlagworte: | Anti-ZEB1, Anti-AREB6, Anti-TCF-8, Anti-Transcription factor 8, Anti-Negative regulator of IL2, Anti-NIL-2-A zinc finger... |
| Anwendung: | IHC |
| Reaktivität: | Human, Mouse |
ab 125,00 €
Anti-BRG1/SMARCA4 (IHC) Artikelnummer: IHC-00466
Protein function: Transcriptional coactivator cooperating with nuclear hormone receptors to potentiate transcriptional activation. Component of the CREST-BRG1 complex, a multiprotein complex that regulates promoter activation by orchestrating a calcium-dependent release of a repressor complex and a recruitment of an...
| Schlagworte: | Anti-SMARCA4, Anti-BAF190A, Anti-SNF2-beta, EC=3.6.4.-, Anti-Protein BRG-1, Anti-Protein brahma homolog 1,... |
| Anwendung: | IHC |
| Reaktivität: | Human, Mouse |
ab 125,00 €
Anti-CASC5 (IHC) Artikelnummer: IHC-00500
Protein function: Performs two crucial functions during mitosis: it is essential for spindle-assembly checkpoint signaling and for correct chromosome alignment. Required for attachment of the kinetochores to the spindle microtubules. Directly links BUB1 and BUB1B to kinetochores. Part of the MIS12 complex, which may...
| Schlagworte: | Anti-CT29, Anti-CASC5, Anti-Blinkin, Anti-AF15q14, Anti-KIAA1570, Anti-Protein CASC5, Anti-Protein D40/AF15q14,... |
| Anwendung: | IHC |
| Reaktivität: | Human |
ab 125,00 €
Anti-YAP1 (IHC) Artikelnummer: IHC-00665
Protein function: Transcriptional regulator which can act both as a coactivator and a corepressor and is the critical downstream regulatory target in the Hippo signaling pathway that plays a pivotal role in organ size control and tumor suppression by restricting proliferation and promoting apoptosis...
| Schlagworte: | Anti-YAP1, Anti-YAP65, Anti-Protein yorkie homolog, Anti-Yes-associated protein 1, Anti-Transcriptional coactivator YAP1,... |
| Anwendung: | IHC, IHC-IF |
| Reaktivität: | Human |
ab 125,00 €
Anti-ECS (DDDDK) Artikelnummer: A190-101A
| Schlagworte: | Anti-FLAG-Tag |
| Anwendung: | WB, IP, ICC, ELISA |
248,00 €
Anti-c-myc Artikelnummer: A190-104A
Protein function: Transcription factor that binds DNA in a non-specific manner, yet also specifically recognizes the core sequence 5'- CAC[GA]TG-3'. Activates the transcription of growth-related genes. [The UniProt Consortium]
| Schlagworte: | Anti-MYC, Anti-bHLHe39, Anti-BHLHE39, Anti-Proto-oncogene c-Myc, Anti-Transcription factor p64, Anti-Myc proto-oncogene... |
| Anwendung: | WB, IP, ICC, ELISA |
248,00 €
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