Produkte von NewEastBio

NewEastBio

NewEast Biosciences aus King of Prussia in Pennsylvania produziert Antikörper, Proteine ​​und Assay-Kits mit einem starken Fokus auf der Forschung an G-Proteinen. Hier finden Sie auch mutationsspezifische Antikörper sowie cAMP- und cGMP-Kits mit außergewöhnlich hoher Spezifität dank des Einsatzes monoklonaler Antikörper.

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Anti-Active Ran, monoclonal
Anti-Active Ran, monoclonal

Artikelnummer: NB-26915

Concentration: 1 mg/ml. Formulation: PBS (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 50% glycerol. Ran (Ras-related nuclear protein) is a member of the Ras-superfamily GTPases. Ran is invovled in the transport of proteins across the nuclear envelope, as well as in microtubule organization during mitosis.
Anwendung: IP, IHC
Antikörper-Typ: Monoclonal
Wirt: Mouse
Reaktivität: Vertebrates
Format: Purified
669,00 €
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Ras (Resistance to audiogenic seizures, Asr), human, recombinant full length, His6-tag [E. coli]
Ras (Resistance to audiogenic seizures, Asr),...

Artikelnummer: NB-10110-1

Small GTPases are a super-family of cellular signaling regulators. Ras belongs to the Ras sub-family of GTPases that regulate cell proliferation, cell motility, and gene transcription. GTP binding increases the activity of Ras, and the hydrolysis of GTP to GDP renders it inactive. GTP hydrolysis is aided by GTPase activating proteins (GAPs), while exchange of GDP for GTP is...
Wirt: E.coli
Reaktivität: Human
MW: 21 kD
Format: Lyophilized
507,00 €
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EGFR protein, L858R
EGFR protein, L858R

Artikelnummer: NB-10230

Protein function: Receptor tyrosine kinase binding ligands of the EGF family and activating several signaling cascades to convert extracellular cues into appropriate cellular responses. Known ligands include EGF, TGFA/TGF-alpha, amphiregulin, epigen/EPGN, BTC/betacellulin, epiregulin/EREG and HBEGF/heparin-binding EGF. Ligand binding triggers receptor homo- and/or...
Reaktivität: Human
426,00 €
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NFE2L2 Protein
NFE2L2 Protein

Artikelnummer: NB-10445

Protein function: Transcription activator that binds to antioxidant response (ARE) elements in the promoter regions of target genes. Important for the coordinated up-regulation of genes in response to oxidative stress. May be involved in the transcriptional activation of genes of the beta-globin cluster by mediating enhancer activity of hypersensitive site 2 of the...
Reaktivität: Human
469,00 €
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NFE2L2 Protein D77V mutant
NFE2L2 Protein D77V mutant

Artikelnummer: NB-10446

Protein function: Transcription activator that binds to antioxidant response (ARE) elements in the promoter regions of target genes. Important for the coordinated up-regulation of genes in response to oxidative stress. May be involved in the transcriptional activation of genes of the beta-globin cluster by mediating enhancer activity of hypersensitive site 2 of the...
Reaktivität: Human
469,00 €
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NFE2L2 Protein R34Q mutant
NFE2L2 Protein R34Q mutant

Artikelnummer: NB-10447

Protein function: Transcription activator that binds to antioxidant response (ARE) elements in the promoter regions of target genes. Important for the coordinated up-regulation of genes in response to oxidative stress. May be involved in the transcriptional activation of genes of the beta-globin cluster by mediating enhancer activity of hypersensitive site 2 of the...
Reaktivität: Human
469,00 €
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NFE2L2 Protein L30F mutant
NFE2L2 Protein L30F mutant

Artikelnummer: NB-10448

Protein function: Transcription activator that binds to antioxidant response (ARE) elements in the promoter regions of target genes. Important for the coordinated up-regulation of genes in response to oxidative stress. May be involved in the transcriptional activation of genes of the beta-globin cluster by mediating enhancer activity of hypersensitive site 2 of the...
Reaktivität: Human
469,00 €
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NFE2L2 Protein E79Q mutant
NFE2L2 Protein E79Q mutant

Artikelnummer: NB-10449

Protein function: Transcription activator that binds to antioxidant response (ARE) elements in the promoter regions of target genes. Important for the coordinated up-regulation of genes in response to oxidative stress. May be involved in the transcriptional activation of genes of the beta-globin cluster by mediating enhancer activity of hypersensitive site 2 of the...
Reaktivität: Human
469,00 €
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NFE2L2 Protein D29G mutant
NFE2L2 Protein D29G mutant

Artikelnummer: NB-10451

Protein function: Transcription activator that binds to antioxidant response (ARE) elements in the promoter regions of target genes. Important for the coordinated up-regulation of genes in response to oxidative stress. May be involved in the transcriptional activation of genes of the beta-globin cluster by mediating enhancer activity of hypersensitive site 2 of the...
Reaktivität: Human
469,00 €
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NFE2L2 Protein V32T mutant
NFE2L2 Protein V32T mutant

Artikelnummer: NB-10452

Protein function: Transcription activator that binds to antioxidant response (ARE) elements in the promoter regions of target genes. Important for the coordinated up-regulation of genes in response to oxidative stress. May be involved in the transcriptional activation of genes of the beta-globin cluster by mediating enhancer activity of hypersensitive site 2 of the...
Reaktivität: Human
469,00 €
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Anti-Orai1 (Orai1-L2)
Anti-Orai1 (Orai1-L2)

Artikelnummer: NB-21002

Concentration: 0.5 mg/ml. Formulation: 50mM NaHCO3-Glycine, 0.15M NaCl, pH7.5. Store-operated calcium channels (SOCs) play essential functions in various physiological processes. Orai1 (also named CRACM1) is a critical molecular component of SOCs. Orai1 protein is a ~35 kDa plasma membrane protein with 4 transmembrane domains. Human patients with a severe combinaed...
Anwendung: ELISA, WB
Antikörper-Typ: Polyclonal
Wirt: Rabbit
Reaktivität: Human
Format: Affinity Purified
296,00 €
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Anti-Rac1
Anti-Rac1

Artikelnummer: NB-21003

Concentration: 0.2 mg/ml. Formulation: PBS (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 50% glycerol. Small GTPases are a super-family of cellular signaling regulators. Rac belongs to the Rho sub-family of GTPases that regulate cell motility, cell division, and gene transcription. GTP binding increases the activity of Rac, and the hydrolysis of GTP to GDP renders it...
Anwendung: ELISA, WB
Antikörper-Typ: Polyclonal
Wirt: Rabbit
Reaktivität: Vertebrates
Format: Purified
296,00 €
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