Produkte von NewEast Biosciences
NewEast Biosciences aus King of Prussia in Pennsylvania produziert Antikörper, Proteine und Assay-Kits mit einem starken Fokus auf der Forschung an G-Proteinen. Hier finden Sie auch mutationsspezifische Antikörper sowie cAMP- und cGMP-Kits mit außergewöhnlich hoher Spezifität dank des Einsatzes monoklonaler Antikörper.
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![Ras (Resistance to audiogenic seizures, Asr), human, recombinant full length, His6-tag [E. coli]](https://www.biomol.com/media/image/50/20/81/NB-10110-1_200x200.jpg "Ras (Resistance to audiogenic seizures, Asr), human, recombinant full length, His6-tag [E. coli]")
Ras (Resistance to audiogenic seizures, Asr),... Artikelnummer: NB-10110-1
Small GTPases are a super-family of cellular signaling regulators. Ras belongs to the Ras sub-family of GTPases that regulate cell proliferation, cell motility, and gene transcription. GTP binding increases the activity of Ras, and the hydrolysis of GTP to GDP renders it inactive. GTP hydrolysis is aided by GTPase...
| Schlagworte: | KRAS, KRAS2 |
| Reaktivität: | Human |
| MW: | 21 kD |
507,00 €
EGFR protein, L858R Artikelnummer: NB-10230
Protein function: Receptor tyrosine kinase binding ligands of the EGF family and activating several signaling cascades to convert extracellular cues into appropriate cellular responses. Known ligands include EGF, TGFA/TGF-alpha, amphiregulin, epigen/EPGN, BTC/betacellulin, epiregulin/EREG and HBEGF/heparin-binding...
| Schlagworte: | EGFR, ERBB, EC=2.7.10.1, Proto-oncogene c-ErbB-1, Epidermal growth factor receptor, Receptor tyrosine-protein kinase erbB-1 |
| Reaktivität: | Human |
426,00 €
NFE2L2 Protein Artikelnummer: NB-10445
Protein function: Transcription activator that binds to antioxidant response (ARE) elements in the promoter regions of target genes. Important for the coordinated up-regulation of genes in response to oxidative stress. May be involved in the transcriptional activation of genes of the beta-globin cluster by mediating...
| Schlagworte: | NRF2, HEBP1, NFE2L2, NFE2-related factor 2, NF-E2-related factor 2, Nuclear factor erythroid 2-related factor 2, Nuclear... |
| Reaktivität: | Human |
469,00 €
NFE2L2 Protein D77V mutant Artikelnummer: NB-10446
Protein function: Transcription activator that binds to antioxidant response (ARE) elements in the promoter regions of target genes. Important for the coordinated up-regulation of genes in response to oxidative stress. May be involved in the transcriptional activation of genes of the beta-globin cluster by mediating...
| Schlagworte: | NRF2, HEBP1, NFE2L2, NFE2-related factor 2, NF-E2-related factor 2, Nuclear factor erythroid 2-related factor 2, Nuclear... |
| Reaktivität: | Human |
469,00 €
NFE2L2 Protein R34Q mutant Artikelnummer: NB-10447
Protein function: Transcription activator that binds to antioxidant response (ARE) elements in the promoter regions of target genes. Important for the coordinated up-regulation of genes in response to oxidative stress. May be involved in the transcriptional activation of genes of the beta-globin cluster by mediating...
| Schlagworte: | NRF2, HEBP1, NFE2L2, NFE2-related factor 2, NF-E2-related factor 2, Nuclear factor erythroid 2-related factor 2, Nuclear... |
| Reaktivität: | Human |
469,00 €
NFE2L2 Protein L30F mutant Artikelnummer: NB-10448
Protein function: Transcription activator that binds to antioxidant response (ARE) elements in the promoter regions of target genes. Important for the coordinated up-regulation of genes in response to oxidative stress. May be involved in the transcriptional activation of genes of the beta-globin cluster by mediating...
| Schlagworte: | NRF2, HEBP1, NFE2L2, NFE2-related factor 2, NF-E2-related factor 2, Nuclear factor erythroid 2-related factor 2, Nuclear... |
| Reaktivität: | Human |
469,00 €
NFE2L2 Protein E79Q mutant Artikelnummer: NB-10449
Protein function: Transcription activator that binds to antioxidant response (ARE) elements in the promoter regions of target genes. Important for the coordinated up-regulation of genes in response to oxidative stress. May be involved in the transcriptional activation of genes of the beta-globin cluster by mediating...
| Schlagworte: | NRF2, HEBP1, NFE2L2, NFE2-related factor 2, NF-E2-related factor 2, Nuclear factor erythroid 2-related factor 2, Nuclear... |
| Reaktivität: | Human |
469,00 €
NFE2L2 Protein D29G mutant Artikelnummer: NB-10451
Protein function: Transcription activator that binds to antioxidant response (ARE) elements in the promoter regions of target genes. Important for the coordinated up-regulation of genes in response to oxidative stress. May be involved in the transcriptional activation of genes of the beta-globin cluster by mediating...
| Schlagworte: | NRF2, HEBP1, NFE2L2, NFE2-related factor 2, NF-E2-related factor 2, Nuclear factor erythroid 2-related factor 2, Nuclear... |
| Reaktivität: | Human |
469,00 €
NFE2L2 Protein V32T mutant Artikelnummer: NB-10452
Protein function: Transcription activator that binds to antioxidant response (ARE) elements in the promoter regions of target genes. Important for the coordinated up-regulation of genes in response to oxidative stress. May be involved in the transcriptional activation of genes of the beta-globin cluster by mediating...
| Schlagworte: | NRF2, HEBP1, NFE2L2, NFE2-related factor 2, NF-E2-related factor 2, Nuclear factor erythroid 2-related factor 2, Nuclear... |
| Reaktivität: | Human |
469,00 €
Anti-Orai1 (Orai1-L2) Artikelnummer: NB-21002
Concentration: 0.5 mg/ml. Formulation: 50mM NaHCO3-Glycine, 0.15M NaCl, pH7.5. Store-operated calcium channels (SOCs) play essential functions in various physiological processes. Orai1 (also named CRACM1) is a critical molecular component of SOCs. Orai1 protein is a ~35 kDa plasma membrane protein with 4...
| Schlagworte: | Anti-ORAI1, Anti-CRACM1, Anti-Protein orai-1, Anti-Transmembrane protein 142A, Anti-Calcium release-activated calcium... |
| Anwendung: | ELISA, WB |
| Reaktivität: | Human |
296,00 €
Anti-Rac1 Artikelnummer: NB-21003
Concentration: 0.2 mg/ml. Formulation: PBS (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 50% glycerol. Small GTPases are a super-family of cellular signaling regulators. Rac belongs to the Rho sub-family of GTPases that regulate cell motility, cell division, and gene transcription. GTP binding increases the activity...
| Schlagworte: | Anti-MIG5, Anti-RAC1, Anti-TC25, Anti-p21-Rac1, Anti-Ras-like protein TC25, Anti-Cell migration-inducing gene 5 protein,... |
| Anwendung: | ELISA, WB |
| Reaktivität: | Vertebrates |
296,00 €
Anti-G.alpha.13 Artikelnummer: NB-21005
Concentration: 0.2 mg/ml. Formulation: PBS (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 50% glycerol. Heterotrimeric G proteins are essential cellular signal transducers. Galpha13 is one of the G proteins that could mediate cell migration and angiogenesis. Other biochemical and physiological functions of Galpha13...
| Schlagworte: | Anti-GNA13, Anti-G alpha-13, Anti-G-protein subunit alpha-13, Anti-Guanine nucleotide-binding protein subunit alpha-13 |
| Anwendung: | ELISA, WB |
| Reaktivität: | Vertebrates |
296,00 €
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