Produkte von NewEastBio

NewEastBio

NewEast Biosciences aus King of Prussia in Pennsylvania produziert Antikörper, Proteine ​​und Assay-Kits mit einem starken Fokus auf der Forschung an G-Proteinen. Hier finden Sie auch mutationsspezifische Antikörper sowie cAMP- und cGMP-Kits mit außergewöhnlich hoher Spezifität dank des Einsatzes monoklonaler Antikörper.

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Anti-G.alpha.i, monoclonal
Anti-G.alpha.i, monoclonal

Artikelnummer: NB-26003

Concentration: 1 mg/ml. Formulation: PBS (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 50% glycerol. Heterotrimeric G proteins are critical cellular signal transducers. Galphai represents one sub-family of G proteins that could mediate the inhibition of adenylyl cyclases. Other biochemical and physiological functions of Galphai proteins are being explored.
Anwendung: ELISA, WB, IHC
Antikörper-Typ: Monoclonal
Wirt: Mouse
Reaktivität: Vertebrates
Format: Purified
323,00 €
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Anti-Ras (G12D), monoclonal
Anti-Ras (G12D), monoclonal

Artikelnummer: NB-26036

Concentration: 1 mg/ml. Formulation: PBS (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 50% glycerol. Ras (G12D) is one type of Ras missense mutations at the codon 12. Ras protein is a membrane-associated GTPase that regulates cell proliferation, differentiation, and survival. Ras G12D mutation results in decreased GTPase activity and constitutive signaling. This mutation is...
Anwendung: ELISA, WB, IHC, IP
Antikörper-Typ: Monoclonal
Wirt: Mouse
Reaktivität: Vertebrates
Format: Purified
669,00 €
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Anti-B-Raf (V600E), monoclonal
Anti-B-Raf (V600E), monoclonal

Artikelnummer: NB-26039

Concentration: 0.5 mg/ml. Formulation: PBS (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 50% glycerol. B-Raf is a member of the Raf family of Ser/Thr protein kinases. It functions downstream of Ras to regulate the MAP kinase signaling pathway. Mutations in the BRAF gene cause diseases. Inherited mutations in BRAF cause cardiofaciocutaneous syndrome. Acquired mutations in...
Anwendung: ELISA, WB, IHC, IP
Antikörper-Typ: Monoclonal
Wirt: Mouse
Format: Purified
669,00 €
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Anti-IDH2 (R172K)
Anti-IDH2 (R172K)

Artikelnummer: NB-26163

Constituents: PBS (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 50% glycerol. Isocitrate dehydrogenase (IDH) catalyze the oxidative decarboxylation of isocitrate to 2-oxoglutarate. The isocitrate and isopropylmalate dehydrogenases family has three members, IDH1, IDH2 and IDH3. IDH2 plays a role in intermediary metabolism and energy production. Defects in IDH2 are the cause...
Anwendung: ELISA, WB, IHC
Antikörper-Typ: Monoclonal
Wirt: Mouse
Reaktivität: Vertebrates
Format: Purified
669,00 €
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Anti-Active  G.alpha.i, monoclonal
Anti-Active G.alpha.i, monoclonal

Artikelnummer: NB-26901

Concentration: 1 mg/ml. Formulation: PBS (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 50% glycerol. Heterotrimeric G proteins are critical cellular signal transducers. G alpha i represents one sub-family of G proteins that could mediate the inhibition of adenylyl cyclases. Other biochemical and physiological functions of G alpha i proteins are being explored.
Anwendung: IP, IHC
Antikörper-Typ: Monoclonal
Wirt: Mouse
Reaktivität: Vertebrates
Format: Purified
669,00 €
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Anti-Active Rac-GTP, monoclonal
Anti-Active Rac-GTP, monoclonal

Artikelnummer: NB-26903

Concentration: 1 mg/ml. Formulation: PBS (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 50% glycerol. Small GTPases are a super-family of cellular signaling regulators. Rac belongs to the Rho sub-family of GTPases that regulate cell motility, cell division, and gene transcription. GTP binding increases the activity of Rac, and the hydrolysis of GTP to GDP renders it...
Anwendung: IP, IHC
Antikörper-Typ: Monoclonal
Wirt: Mouse
Reaktivität: Vertebrates
Format: Purified
669,00 €
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Anti-Active RhoA, monoclonal
Anti-Active RhoA, monoclonal

Artikelnummer: NB-26904

Concentration: 1 mg/ml. Formulation: PBS (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 50% glycerol. Small GTPases are a super-family of cellular signaling regulators. RhoA belongs to the Rho sub-family of GTPases. Rho proteins play critical roles in many actin cytoskeleton- dependent processes including platelet aggregation, cell motility, contraction, and cytokinesis. It...
Anwendung: IP, IHC
Antikörper-Typ: Monoclonal
Wirt: Mouse
Reaktivität: Vertebrates
Format: Purified
669,00 €
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Anti-Active Cdc42, monoclonal
Anti-Active Cdc42, monoclonal

Artikelnummer: NB-26905

Concentration: 1 mg/ml. Formulation: PBS (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 50% glycerol. Small GTPases are a super-family of cellular signaling regulators. Cdc42 belongs to the Rho sub-family of GTPases that regulate cell motility, cell division, and gene transcription. GTP binding increases the activity of Cdc42, and the hydrolysis of GTP to GDP renders it...
Anwendung: IP, IHC
Antikörper-Typ: Monoclonal
Wirt: Mouse
Reaktivität: Vertebrates
Format: Purified
669,00 €
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Anti-Active Ras, monoclonal
Anti-Active Ras, monoclonal

Artikelnummer: NB-26909

Concentration: 1 mg/ml. Formulation: PBS (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 50% glycerol. Small GTPases are a super-family of cellular signaling regulators. Ras belongs to the Ras sub-family of GTPases that regulate cell proliferation, cell motility, and gene transcription. GTP binding increases the activity of Ras, and the hydrolysis of GTP to GDP renders it...
Anwendung: IP, IHC
Antikörper-Typ: Monoclonal
Wirt: Mouse
Reaktivität: Vertebrates
Format: Purified
669,00 €
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Anti-PIK3CA (H1047R)
Anti-PIK3CA (H1047R)

Artikelnummer: NB-21146

Concentration: 0.1 mg/ml. Formulation: PBS (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 50% glycerol. Phosphatidylinositol 3-kinase is composed of an 85 kDa regulatory subunit and a 110 kDa catalytic subunit. The catalytic subunit is encoded by the PIK3CA gene. It phosphorylates PtdIns, PtdIns4P and PtdIns(4,5)P2. The PIK3CA gene is one of the most frequently mutated genes...
Anwendung: ELISA, WB, IF, IHC
Antikörper-Typ: Polyclonal
Wirt: Rabbit
Reaktivität: Vertebrates
Format: Purified
669,00 €
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Anti-Active Ral, monoclonal
Anti-Active Ral, monoclonal

Artikelnummer: NB-26913

Concentration: 1 mg/ml. Formulation: PBS (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 50% glycerol. The Ras- like small G proteins, RalA and RalB, are important components of Ras signaling pathways, implicated in the initiation and m aintenance of tumorigenic transformation, as well as vesicle transport, apoptosis, transcription, cell migration, and cell proliferation....
Anwendung: IP, IHC
Antikörper-Typ: Monoclonal
Wirt: Mouse
Reaktivität: Vertebrates
Format: Purified
669,00 €
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Anti-Active Arf6, monoclonal
Anti-Active Arf6, monoclonal

Artikelnummer: NB-26918

Concentration: 1 mg/ml. Formulation: PBS (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 50% glycerol. ARF6 ( ADP- ribosylation factor 6 ) is a member of the ARF super - family. ARF genes encode small GTPases that increase the ADP- ribosyltransferase activity of cholera toxin and are critical for vesicular trafficking as activators of phospholipase D. Arf6 regulate s membrane...
Anwendung: IP, IHC
Antikörper-Typ: Monoclonal
Wirt: Mouse
Reaktivität: Vertebrates
Format: Purified
669,00 €
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