Produkte von LKT Laboratories

LKT

LKT Laboratories ist ein F&E Unternehmen, das sich auf die Entwicklung von pharmakologischen Substanzen zur Bekämpfung von Krebs- und anderen Erkrankungen konzentriert. Bei der Herstellung dieser Wirkstoffe entstehen Substanzen, die auch für die Life-Science-Forschung als Bioreagenzien extrem nützlich sind und von LKT im analytischen Maßstab angeboten werden.

Mehr unter: www.lktlabs.com

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Nitisinone
Nitisinone

Artikelnummer: LKT-N3476.50

Nitisinone is a nitrobenzene inhibitor of HPPD, an enzyme involved in tyrosine degradation. Nitisinone is clinically used to slow the effects of hereditary type 1 tyrosinemia and as a potential treatment for alkaptonuria.
Schlagworte: NTBC, orfadin
Anwendung: 4-hydroxyphenylpyruvate dioxygenase inhibitor
CAS 104206-65-7
MW: 329.23 D
ab 63,00 €
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Carmustine
Carmustine

Artikelnummer: LKT-C0173.100

Carmustine is an antitumor agent.
Schlagworte: BCNU, bis-chloroethylnitrosourea
Anwendung: Anticancer agent
CAS 154-93-8
MW: 214,05 D
ab 75,00 €
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Isoflurane
Isoflurane

Artikelnummer: LKT-I7258.250

Isoflurane is an anesthetic most commonly used in veterinary medicine. Isoflurane exhibits cardiomodulatory, neuromodulatory, and pro-inflammatory activities. In diabetic rats, isofluorane decreases cardiac force and intracellular Ca2+ amplitude. Isoflurane also increases IL-6 and NF-kappaB levels in glioma cells...
Anwendung: Anesthetic [inhalation]
CAS 26675-46-7
MW: 184.49 D
ab 58,00 €
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Paclitaxel (Semi-synthetic)
Paclitaxel (Semi-synthetic)

Artikelnummer: LKT-P0093.100

A natural diterpenoid originally isolated from the stem bark of Taxus brevifolia. It promotes the assembly of stable microtubules and inhibits the disassembly process of microtubules to tubulin by calcium ions and by low temperature. Taxol was shown to have activity against cancers, such as P388 and L1210 leukemia,...
Schlagworte: Taxol
Anwendung: Chemopreventive agent
CAS 33069-62-4
MW: 853,9 D
ab 90,00 €
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R,S-Sulforaphane
R,S-Sulforaphane

Artikelnummer: LKT-S8044.50

R,S-Sulforaphane is a synthetic version of the naturally occurring compound, R-sulforaphane, from Broccoli. It is a racemic mixture of both the R and S isomers. At room temperature, it is a very slightly yellowish viscous liquid. Its isothiocyanate group reacts with protic solvents such as water and ethanol to form...
Anwendung: Chemopreventive agent
CAS 4478-93-7
MW: 177,29 D
ab 186,00 €
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Celecoxib
Celecoxib

Artikelnummer: LKT-C1644.1

Celecoxib is a selective COX 2 inhibitor.
Anwendung: COX-2 inhibitor
CAS 169590-42-5
MW: 381,37 D
ab 118,00 €
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Methysticin
Methysticin

Artikelnummer: LKT-M1679.10

One of the main components in kava kava extract. It has anxiolytic effect and neuroprotective property.
Anwendung: Metabolic studies
CAS 495-85-2
MW: 274,27 D
ab 280,00 €
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Spiramycin
Spiramycin

Artikelnummer: LKT-S6232.5

A macrolide antibiotic. It has been shown to decrease the replication index of humanlymphocytes.
Schlagworte: SPM, RP-5337
Anwendung: Antibiotic, macrolide
CAS 8025-81-8
MW: 842,05 D
ab 104,00 €
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GSK1120212
GSK1120212

Artikelnummer: LKT-G7440.5

GSK1120212 inhibits MEK1/2 and is currently in clinical trials as a potential treatment for melanoma. GSK1120212 exhibits anticancer chemotherapeutic activity, upregulating p27 expression and inhibiting growth in colorectal cancer cells and suppressing tumor growth in colorectal cancer xenografts.
Schlagworte: Trametinib, JTP-74057
Anwendung: MEK1/2 inhibitor
CAS 871700-17-3
MW: 615.39 D
ab 118,00 €
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ASTX660
ASTX660

Artikelnummer: LKT-A744789.1

ASTX660 is an inhibitor of apoptosis proteins found to target BIR3 domain of cIAP1/2 and XIAP through a TNFalpha dependent mechanism in melanoma, breast cancer, and lymphoma cell studies. In a breast cancer xenograft model ASTX660 inhibited tumor growth while displaying no significant adverse effects. Treatment of...
Schlagworte: ASTX660, ASTX-660, ASTX 660, Ethanone,...
Anwendung: CIAP / XIAP dual antagonist
CAS 1799328-86-1
MW: 539.7 D
ab 453,00 €
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Baloxavir
Baloxavir

Artikelnummer: LKT-B011458.1

Baloxavir, and its prodrug baloxavir marboxil, is a cap-dependent endonuclease inhibitor, leading to inhibition of RNA transcription and replication. Baloxavir shows potent activity against two influenza A strains with noted synergistic effects when used in combination with oseltamivir. Baloxavir has also been...
Schlagworte: Baloxavir acid, 4G86Y4JT3F,...
Anwendung: Antiviral, Cap-dependent endonuclease inhibitor
CAS 1985605-59-1
MW: 483.5 D
ab 101,00 €
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Baloxavir Marboxil
Baloxavir Marboxil

Artikelnummer: LKT-B011460.100

Baloxavir, and its prodrug baloxavir marboxil, is a cap-dependent endonuclease inhibitor, leading to inhibition of RNA transcription and replication. Baloxavir shows potent activity against two influenza A strains with noted synergistic effects when used in combination with oseltamivir. Baloxavir has also been...
Schlagworte: Xofluza, S-033188,...
Anwendung: Antiviral, Cap-dependent endonuclease inhibitor, Prodrug
CAS 1985606-14-1
MW: 571.6 D
ab 123,00 €
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