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Leupeptin (Ac-Leu-Leu-Arginal-hemisulfate) Artikelnummer: 12136.25
Leupeptin, also known as N-acetyl-L-leucyl-L-leucyl-L-argininal, is a naturally occurring protease inhibitor that can inhibit cysteine, serine and threonine peptidases. It is often used during in vitro experiments when a specific enzymatic reaction is being studied. When cells are lysed for these studies, proteases,...
| Anwendung: | Inhibitor |
| CAS | 103476-89-7 |
| MW: | 475.6 |
ab 83,00 €
Bluo-Gal, pure Artikelnummer: 50375.1
5-Bromo-3-Indolyl-ß-D-Galactopyranoside (Bluo-Gal) is a substrate for the histochemical localization of ß-galactosidase. Bluo-Gal is an alternative to X-Gal, producing a darker blue color.
| Schlagworte: | 5-Bromo-3-indolyl beta-D-galactopyranoside |
| Anwendung: | Beta-Galactosidase substrate |
| CAS | 97753-82-7 |
| MW: | 374.20 |
176,00 €
Dithiothreitol (DTT) Artikelnummer: 04010.10
DTT is an unusually strong reducing agent, because once oxidized, it forms a stable six-membered ring with an internal disulfide bond. The reduction usually does not stop at the mixed-disulfide species because the second thiol of DTT has a high propensity to close the ring, forming oxidized DTT and leaving behind a...
| Anwendung: | Reducing agent |
| CAS | 3483-12-3 |
| MW: | 154.25 |
ab 40,00 €
Glycine, ultra pure Artikelnummer: 04943.1
Glycine (abbreviated as Gly or G) is the smallest of the 20 amino acids commonly found in proteins, having a hydrogen substituent as its side-chain. Its codons are GGU, GGC, GGA, GGG of the genetic code. Glycine is often used as a counterion in SDS-PAGE and in buffers for western blotting.
| Anwendung: | Buffer component, Protein stabilization |
| CAS | 56-40-6 |
| MW: | 75.07 |
ab 30,00 €
Isopropyl-beta-D-thiogalacto- pyranoside (IPTG) Artikelnummer: 05684.5
Purity: >99%. Free of dioxane and other solvents. For use im molecular biology. In combination with X-Gal (cat# 02249) it is used to detect lac+ colonies in cloning experiments.
| Anwendung: | Inducer of beta-galactosidase |
| CAS | 367-93-1 |
| MW: | 238.30 |
ab 32,00 €
Dimethylsulfoxide (DMSO) Artikelnummer: 54686.100
DMSO is a polar aprotic solvent that dissolves both polar and nonpolar compounds and is miscible in a wide range of organic solvents as well as water. DMSO is less toxic than other members of this class, such as dimethylformamide, dimethylacetamide, N-methyl-2-pyrrolidone, and HMPA. DMSO is also used in PCR to...
| Anwendung: | Protein stabilization |
| CAS | 67-68-5 |
| MW: | 78.13 |
ab 29,00 €
Rosiglitazone Artikelnummer: Cay71740-10
Rosiglitazone is a thiazolidinedione agonist of peroxisome proliferator-activated receptor gamma (PPARgamma) that binds to the ligand binding domain (LBD) of PPARgamma with a Kd value of 43 nM. It selectively activates chimeras containing the LBDs of PPARgamma over PPARalpha and PPARdelta in a cell-based reporter...
| Schlagworte: | BRL 49653, 5-[[4-[2-(methyl-2-pyridinylamino)ethoxy]phenyl]methyl]-2,4-thiazolidinedione |
| Anwendung: | PPARgamma agonist |
| CAS | 122320-73-4 |
| MW: | 357.4 D |
ab 35,00 €
Thiazolyl blue (MTT) 3-(4,5-Dimethyl-2-thiazolyl)-2... Artikelnummer: 15655.1
MTT, a yellow tetrazole, is reduced to purple formazan in living cells. A solubilization solution (usually either dimethyl sulfoxide, an acidified ethanol solution, or a solution of the detergent sodium dodecyl sulfate in diluted hydrochloric acid) is added to dissolve the insoluble purple formazan product into a...
| Anwendung: | Cell viability assay |
| CAS | 298-93-1 |
| MW: | 414.33 |
ab 28,00 €
NADH, disodium salt Artikelnummer: 16132.1
Assay: >85% enzymatically
| Schlagworte: | beta-Nicotinamide-adenine-dinucleotide, reduced Na2-salt |
| CAS | 606-68-8 |
| MW: | 709.4 D |
ab 46,00 €
CHIR99021 Artikelnummer: Cay13122-1
Glycogen synthase kinase 3 (GSK3) is a serine/threonine kinase that plays a key inhibitory role in both the insulin and Wnt signaling pathways. CHIR99021 is an aminopyrimidine derivative that inhibits GSK3alpha and GSK3beta with IC50 values of 10 and 6.7 nM, respectively. When tested against twenty different protein...
| Schlagworte: | CT 99021,... |
| Anwendung: | GSK3alpha and GSK3beta inhibitor |
| CAS | 252917-06-9 |
| MW: | 465.3 D |
ab 32,00 €
NADPH, tetrasodium salt Artikelnummer: 16156.100
Nicotinamide adenine dinucleotide phosphate, abbreviated NADP+ or, in older notation, TPN (triphosphopyridine nucleotide), is a coenzyme used in anabolic reactions, such as lipid and nucleic acid synthesis, which require NADPH as a reducing agent. NADPH is the reduced form of NADP+. NADP+ differs from NAD+ in the...
| Schlagworte: | beta-Nicotinamide-adenine-dinucleotide phosphate, reduced Na4-salt |
| CAS | 53-57-6 |
| MW: | 833.36 D |
ab 72,00 €
15-deoxy-Delta12,14-Prostaglandin J2 Artikelnummer: Cay18570-1
15-deoxy-Delta12,14-Prostaglandin J2 (15-deoxy-Delta12,14-PGJ2) is formed from PGD2 by the elimination of two molecules of water. It binds selectively to PPARgamma with an EC50 value of 2 µM in a murine chimera system. 15-deoxy-Delta12,14-PGJ2 is more potent than PGD2, Delta12-PGJ2, and PGJ2 in stimulating...
| Schlagworte: | 15-deoxy-Delta12,14-PGJ2, 11-oxo-prosta-5Z,9,12E,14E-tetraen-1-oic acid |
| Anwendung: | Bioactive lipid assays |
| CAS | 87893-55-8 |
| MW: | 316.4 D |
ab 32,00 €