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Leupeptin (Ac-Leu-Leu-Arginal-hemisulfate) Artikelnummer: 12136.25
Purity: >96.5%, A reversible inhibitor of trypsin-like proteases and cysteine proteases. Soluble in water, ethanol, acetic acid and DMF. Stock solution: 10 mM in water, stable for 1 month at -20 °C. Effective conc.: 1-10 µM.
| Anwendung: | Inhibitor |
| CAS | 103476-89-7 |
| MW: | 475.6 |
ab 83,00 €
Thiazolyl blue (MTT) 3-(4,5-Dimethyl-2-thiazolyl)-2... Artikelnummer: 15655.10
The water soluble MTT yields a yellowish solution. It is converted by mitochondrial dehydrogenases of metabolically active cells to an insoluble formazan product, which can be solubilized with DMSO. Read at 510 nm.
| Anwendung: | Cell viability assay |
| CAS | 298-93-1 |
| MW: | 414.33 |
ab 28,00 €
Dithiothreitol (DTT) Artikelnummer: 04010.5
Cleland's reagent. Protective reagent for sulfhydryl groups of proteins and enzymes. maintains monothiols in the reduced state and reduces disulfides quantitatively.
| Anwendung: | Reducing agent |
| CAS | 3483-12-3 |
| MW: | 154.25 |
ab 40,00 €
Glycine, ultra pure Artikelnummer: 04943.2500
Purity: >99.0%. Widely used as a buffer component in Laemmli gels and other applications.
| Anwendung: | Buffer component, Protein stabilization |
| CAS | 56-40-6 |
| MW: | 75.07 |
ab 30,00 €
NADPH, tetrasodium salt Artikelnummer: 16156.500
Nicotinamide adenine dinucleotide phosphate, abbreviated NADP+ or, in older notation, TPN (triphosphopyridine nucleotide), is a coenzyme used in anabolic reactions, such as lipid and nucleic acid synthesis, which require NADPH as a reducing agent. NADPH is the reduced form of NADP+. NADP+ differs from NAD+ in the...
| Schlagworte: | beta-Nicotinamide-adenine-dinucleotide phosphate, reduced Na4-salt |
| CAS | 53-57-6 |
| MW: | 833.36 D |
ab 72,00 €
Dimethylsulfoxide (DMSO) Artikelnummer: 54686.500
Assay (GC): min. 99.5%. Low concentrations of DMSO can stabilze proteins, although at higher conc. denaturation may occur. 10% DMSO is used for freezing of cells.
| Anwendung: | Protein stabilization |
| CAS | 67-68-5 |
| MW: | 78.13 |
ab 29,00 €
Isoflurane Artikelnummer: LKT-I7258.250
Isoflurane is an anesthetic most commonly used in veterinary medicine. Isoflurane exhibits cardiomodulatory, neuromodulatory, and pro-inflammatory activities. In diabetic rats, isofluorane decreases cardiac force and intracellular Ca2+ amplitude. Isoflurane also increases IL-6 and NF-kappaB levels in glioma cells...
| Anwendung: | Anesthetic [inhalation] |
| CAS | 26675-46-7 |
| MW: | 184.49 D |
ab 58,00 €
2-NBDG Artikelnummer: Cay11046-10
2-NBDG is a fluorescent derivative of glucose whose uptake is competitively inhibited by D-glucose (Cay-23733), but not L-glucose (Cay-20829) or sucrose, in E. coli. It has been used to monitor glucose uptake by bacteria and live mammalian cells and in tumor biopsies. 2-NBDG displays excitation/emission maxima of...
| Schlagworte: | NBD-Glucose, 2-deoxy-2-[(7-nitro-2,1,3-benzoxadiazol-4-yl)amino]-D-glucose |
| Anwendung: | Deoxyglucose analog |
| CAS | 186689-07-6 |
| MW: | 342.3 D |
ab 44,00 €
Temozolomide Artikelnummer: Cay14163-100
Temozolomide (TMZ) is an imidazotetrazine that is converted to a compound capable of alkylating DNA, thus interfering with DNA replication and leading to cytotoxicity in proliferating cells. TMZ is rapidly and completely absorbed from the gastrointestinal tract after oral administration and readily crosses the...
| Schlagworte: | CCRG 81045, MB 39831, Methazolastone, NSC 362856, Temodal, TMZ,... |
| Anwendung: | DNA alkylating agent, Apoptosis inducer |
| CAS | 85622-93-1 |
| MW: | 194.2 D |
ab 49,00 €
Quercetin Artikelnummer: Cay10005169-5
Quercetin is an abundant flavonoid that has been isolated from a variety of fruits and vegetables and has diverse biological activities, including antioxidant, anticancer, and anti-inflammatory properties. Quercetin (5-100 mg/kg) reduces autophagy, decreases the levels of reactive oxygen species (ROS) and...
| Schlagworte: | 2-(3,4-dihydroxyphenyl)-3,5,7-trihydroxy-4H-1-benzopyran-4-one |
| Anwendung: | Phosphodiesterase inhibitor |
| CAS | 117-39-5 |
| MW: | 302.2 D |
ab 19,00 €
25-hydroxy Vitamin D3 Artikelnummer: Cay9000683-1
Deficiency of vitamin D leads to abnormal calcium and phosphorus metabolism, contributing to deficiencies in bone formation, neuromuscular function, and inflammatory response. 25-hydroxy Vitamin D3 is an intermediate in the pathway leading to the production of 1,25-dihydroxy vitamin D3, the most receptor-active form...
| Schlagworte: | 25-hydroxy Cholecalciferol, RO 8-8892, Rovimix Hy-D, U 32070E,... |
| Anwendung: | Vitamin D Ligand |
| CAS | 19356-17-3 |
| MW: | 400.6 D |
ab 82,00 €
Olaparib Artikelnummer: Cay10621-5
Many of the products generated by alkylating agents on DNA can be efficiently repaired by normal base excision repair (BER). Some poly(ADP-ribose) polymerases (PARPs) assist in the repair of single-strand DNA nicks, an important step in BER. Olaparib is a potent inhibitor of PARP1 and PARP2 (IC50 = 5 and 1 nM,...
| Schlagworte: | AZD 2281, Ku-0059436, 4-[[3-[[4-(cyclopropylcarbonyl)-1-piperazinyl]carbonyl]-4-fluorophenyl]methyl]-1(2H)-phthalazinone |
| Anwendung: | PARP1 / PARP2 inhibitor |
| CAS | 763113-22-0 |
| MW: | 434.5 D |
ab 49,00 €
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