Biochemikalien

Hier finden Sie ein breites Portfolio von Biochemikalien: Inhibitoren, Liganden und Substrate diverser Enzyme und Rezeptoren, Regulatoren, Assay Komponenten und Farbstoffe. Außerdem finden Sie in dieser Kategorie verschiedene Saccharide, Aminosäuren, Antioxidantien sowie diverse weitere Reagenzien für die biochemische Arbeit.

Hier finden Sie ein breites Portfolio von Biochemikalien: Inhibitoren, Liganden und Substrate diverser Enzyme und Rezeptoren, Regulatoren, Assay Komponenten und Farbstoffe. Außerdem finden Sie in... mehr erfahren »
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Biochemikalien

Hier finden Sie ein breites Portfolio von Biochemikalien: Inhibitoren, Liganden und Substrate diverser Enzyme und Rezeptoren, Regulatoren, Assay Komponenten und Farbstoffe. Außerdem finden Sie in dieser Kategorie verschiedene Saccharide, Aminosäuren, Antioxidantien sowie diverse weitere Reagenzien für die biochemische Arbeit.

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Leupeptin (Ac-Leu-Leu-Arginal-hemisulfate)
Leupeptin (Ac-Leu-Leu-Arginal-hemisulfate)

Artikelnummer: 12136.25

Purity: >96.5%, A reversible inhibitor of trypsin-like proteases and cysteine proteases. Soluble in water, ethanol, acetic acid and DMF. Stock solution: 10 mM in water, stable for 1 month at -20 °C. Effective conc.: 1-10 µM.
Anwendung: Inhibitor
CAS 103476-89-7
MW: 475.6
ab 83,00 €
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Thiazolyl blue (MTT) 3-(4,5-Dimethyl-2-thiazolyl)-2 ,5-diphenyl-2H-tetrazolium bromide
Thiazolyl blue (MTT) 3-(4,5-Dimethyl-2-thiazolyl)-2...

Artikelnummer: 15655.10

The water soluble MTT yields a yellowish solution. It is converted by mitochondrial dehydrogenases of metabolically active cells to an insoluble formazan product, which can be solubilized with DMSO. Read at 510 nm.
Anwendung: Cell viability assay
CAS 298-93-1
MW: 414.33
ab 28,00 €
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Dithiothreitol (DTT)
Dithiothreitol (DTT)

Artikelnummer: 04010.5

Cleland's reagent. Protective reagent for sulfhydryl groups of proteins and enzymes. maintains monothiols in the reduced state and reduces disulfides quantitatively.
Anwendung: Reducing agent
CAS 3483-12-3
MW: 154.25
ab 40,00 €
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Glycine, ultra pure
Glycine, ultra pure

Artikelnummer: 04943.2500

Purity: >99.0%. Widely used as a buffer component in Laemmli gels and other applications.
Anwendung: Buffer component, Protein stabilization
CAS 56-40-6
MW: 75.07
ab 30,00 €
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NADPH, tetrasodium salt
NADPH, tetrasodium salt

Artikelnummer: 16156.500

Nicotinamide adenine dinucleotide phosphate, abbreviated NADP+ or, in older notation, TPN (triphosphopyridine nucleotide), is a coenzyme used in anabolic reactions, such as lipid and nucleic acid synthesis, which require NADPH as a reducing agent. NADPH is the reduced form of NADP+. NADP+ differs from NAD+ in the...
Schlagworte: beta-Nicotinamide-adenine-dinucleotide phosphate, reduced Na4-salt
CAS 53-57-6
MW: 833.36 D
ab 72,00 €
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Dimethylsulfoxide (DMSO)
Dimethylsulfoxide (DMSO)

Artikelnummer: 54686.500

Assay (GC): min. 99.5%. Low concentrations of DMSO can stabilze proteins, although at higher conc. denaturation may occur. 10% DMSO is used for freezing of cells.
Anwendung: Protein stabilization
CAS 67-68-5
MW: 78.13
ab 29,00 €
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Isoflurane
Isoflurane

Artikelnummer: LKT-I7258.250

Isoflurane is an anesthetic most commonly used in veterinary medicine. Isoflurane exhibits cardiomodulatory, neuromodulatory, and pro-inflammatory activities. In diabetic rats, isofluorane decreases cardiac force and intracellular Ca2+ amplitude. Isoflurane also increases IL-6 and NF-kappaB levels in glioma cells...
Anwendung: Anesthetic [inhalation]
CAS 26675-46-7
MW: 184.49 D
ab 58,00 €
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2-NBDG
2-NBDG

Artikelnummer: Cay11046-10

2-NBDG is a fluorescent derivative of glucose whose uptake is competitively inhibited by D-glucose (Cay-23733), but not L-glucose (Cay-20829) or sucrose, in E. coli. It has been used to monitor glucose uptake by bacteria and live mammalian cells and in tumor biopsies. 2-NBDG displays excitation/emission maxima of...
Schlagworte: NBD-Glucose, 2-deoxy-2-[(7-nitro-2,1,3-benzoxadiazol-4-yl)amino]-D-glucose
Anwendung: Deoxyglucose analog
CAS 186689-07-6
MW: 342.3 D
ab 44,00 €
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Temozolomide
Temozolomide

Artikelnummer: Cay14163-100

Temozolomide (TMZ) is an imidazotetrazine that is converted to a compound capable of alkylating DNA, thus interfering with DNA replication and leading to cytotoxicity in proliferating cells. TMZ is rapidly and completely absorbed from the gastrointestinal tract after oral administration and readily crosses the...
Schlagworte: CCRG 81045, MB 39831, Methazolastone, NSC 362856, Temodal, TMZ,...
Anwendung: DNA alkylating agent, Apoptosis inducer
CAS 85622-93-1
MW: 194.2 D
ab 49,00 €
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Quercetin
Quercetin

Artikelnummer: Cay10005169-5

Quercetin is an abundant flavonoid that has been isolated from a variety of fruits and vegetables and has diverse biological activities, including antioxidant, anticancer, and anti-inflammatory properties. Quercetin (5-100 mg/kg) reduces autophagy, decreases the levels of reactive oxygen species (ROS) and...
Schlagworte: 2-(3,4-dihydroxyphenyl)-3,5,7-trihydroxy-4H-1-benzopyran-4-one
Anwendung: Phosphodiesterase inhibitor
CAS 117-39-5
MW: 302.2 D
ab 19,00 €
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25-hydroxy Vitamin D3
25-hydroxy Vitamin D3

Artikelnummer: Cay9000683-1

Deficiency of vitamin D leads to abnormal calcium and phosphorus metabolism, contributing to deficiencies in bone formation, neuromuscular function, and inflammatory response. 25-hydroxy Vitamin D3 is an intermediate in the pathway leading to the production of 1,25-dihydroxy vitamin D3, the most receptor-active form...
Schlagworte: 25-hydroxy Cholecalciferol, RO 8-8892, Rovimix Hy-D, U 32070E,...
Anwendung: Vitamin D Ligand
CAS 19356-17-3
MW: 400.6 D
ab 82,00 €
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Olaparib
Olaparib

Artikelnummer: Cay10621-5

Many of the products generated by alkylating agents on DNA can be efficiently repaired by normal base excision repair (BER). Some poly(ADP-ribose) polymerases (PARPs) assist in the repair of single-strand DNA nicks, an important step in BER. Olaparib is a potent inhibitor of PARP1 and PARP2 (IC50 = 5 and 1 nM,...
Schlagworte: AZD 2281, Ku-0059436, 4-[[3-[[4-(cyclopropylcarbonyl)-1-piperazinyl]carbonyl]-4-fluorophenyl]methyl]-1(2H)-phthalazinone
Anwendung: PARP1 / PARP2 inhibitor
CAS 763113-22-0
MW: 434.5 D
ab 49,00 €
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