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Ionomycin (calcium salt) Artikelnummer: Cay11932-1
Ionomycin is a selective calcium ionophore derived from S. conglobatus that mobilizes intracellular calcium stores. It is used as a research tool to raise the intracellular level of calcium, to study calcium transport across biological membranes, and to stimulate the intracellular production of cytokines. This...
| Schlagworte: | 11,19R,21S-trihydroxy-4R,6S,8S,12R,14R,18R,20S-heptamethyl-22-[octahydro-5'S-[1R-hydroxyethyl]-2S,5'-dimethyl[2,2'R-bifura... |
| Anwendung: | Calcium ionophore |
| CAS | 56092-82-1 |
| MW: | 747.1 D |
ab 32,00 €
Latrunculin B Artikelnummer: AG-CN2-0031-M001
Isolated from Latrunculia magnifica. Cell permeable marine toxin. Disrupts microfilament-mediated processes. Actin polymerization inhibitor in vitro and in vivo by the formation of a 1:1 complex with monomeric G-actin. Less potent than Latrunculin A. May have fewer unwanted effects than latrunculin A and may be...
| Schlagworte: | LAT-B, NSC 339663 |
| Anwendung: | Actin polymerization inhibitor |
| CAS | 76343-94-7 |
| MW: | 395,5 D |
ab 99,00 €
NEU
COVID-19 Forschung
Remdesivir Artikelnummer: Cay30354-5
Remdesivir is a prodrug form of the antiviral nucleoside analog GS-441524 (Cay-30469). Upon entry into cells, remdesivir is metabolized into the nucleotide triphosphate GS-441524. Remdesivir is active against Middle East respiratory syndrome coronavirus (MERS-CoV) and severe acute respiratory syndrome CoV (SARS-CoV)...
| Schlagworte: | GS-5734, N-[(S)-hydroxyphenoxyphosphinyl)-L-alanine, 2-ethylbutyl ester, 6-ester with... |
| Anwendung: | GS-441524 prodrug, SARS type antiviral |
| CAS | 1809249-37-3 |
| MW: | 602.6 D |
ab 110,00 €
(±)-EX-527 Artikelnummer: Cay10009798-5
EX-527 is an inhibitor of sirtuin 1 (SIRT1, IC50 = 0.098 µM). It is selective for SIRT1 over SIRT2, and SIRT3 (IC50s = 19.6 and 48.7 µM, respectively) and the cytochrome P450 (CYP) isoforms CYP3A4, CYP2D6, CYP2C9, CYP2C19, and CYP1A2 at 1 µM. EX-527 (50 µM) induces cell cycle arrest at the G1 phase in MCF-7 cells.
| Schlagworte: | 6-chloro-2,3,4,9-tetrahydro-1H-carbazole-1-carboxamide |
| Anwendung: | SIRT1 inhibitor |
| CAS | 49843-98-3 |
| MW: | 248.7 D |
ab 32,00 €
Leupeptin (Ac-Leu-Leu-Arginal-hemisulfate) Artikelnummer: 12136.100
Purity: >96.5%, A reversible inhibitor of trypsin-like proteases and cysteine proteases. Soluble in water, ethanol, acetic acid and DMF. Stock solution: 10 mM in water, stable for 1 month at -20 °C. Effective conc.: 1-10 µM.
| Anwendung: | Inhibitor |
| CAS | 103476-89-7 |
| MW: | 475.6 |
ab 83,00 €
Imipenem (hydrate) Artikelnummer: Cay16039-100
Imipenem is an intravenous beta-lactam antibiotic effective against a wide range of Gram-positive and Gram-negative bacteria (MICs range from 0.5-2 µg/ml for E. cloacae and P. aeruginosa), including several multi-drug resistant bacterial species. Imipenem acts by interfering with bacterial cell wall synthesis.
| Schlagworte: | N-Formimidoyl Thienamycin,... |
| Anwendung: | Antibacterial antibiotic, Peptidoglycan biosynthesis inhibitor |
| CAS | 74431-23-5 |
| MW: | 317.4 D |
ab 57,00 €
BCIP, p-toluidine salt Artikelnummer: 02291.250
Soluble in DMF, hardly soluble in water. Use as alkaline phosphatase substrate forming a water insoluble blue reaction product. Often used together with NBT (Art.-Nr. 06428) for immunocytochemistry.
| Anwendung: | Substrate for alkaline phosphatase |
| CAS | 6578-06-9 |
| MW: | 433.60 |
ab 53,00 €
NADH, disodium salt Artikelnummer: 16132.1
Assay: >85% enzymatically
| Schlagworte: | beta-Nicotinamide-adenine-dinucleotide, reduced Na2-salt |
| CAS | 606-68-8 |
| MW: | 709.4 D |
ab 46,00 €
Thiazolyl blue (MTT) 3-(4,5-Dimethyl-2-thiazolyl)-2... Artikelnummer: 15655.1
The water soluble MTT yields a yellowish solution. It is converted by mitochondrial dehydrogenases of metabolically active cells to an insoluble formazan product, which can be solubilized with DMSO. Read at 510 nm.
| Anwendung: | Cell viability assay |
| CAS | 298-93-1 |
| MW: | 414.33 |
ab 28,00 €
Glycine, ultra pure Artikelnummer: 04943.1
Purity: >99.0%. Widely used as a buffer component in Laemmli gels and other applications.
| Anwendung: | Buffer component, Protein stabilization |
| CAS | 56-40-6 |
| MW: | 75.07 |
ab 30,00 €
Isopropyl-beta-D-thiogalacto- pyranoside (IPTG) Artikelnummer: 05684.25
Purity: >99%. Free of dioxane and other solvents. For use im molecular biology. In combination with X-Gal (cat# 02249) it is used to detect lac+ colonies in cloning experiments.
| Anwendung: | Inducer of beta-galactosidase |
| CAS | 367-93-1 |
| MW: | 238.30 |
ab 32,00 €
NAD+, free acid Artikelnummer: 16110.1
Assay anhydrous: >97.5% enzymatically
| Schlagworte: | NAD+ beta-Nicotinamide-adenine-dinucleotide, oxidized form |
| CAS | 53-84-9 |
| MW: | 663.44 D |
ab 27,00 €
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