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COVID-19 Forschung
Spike (SARS-CoV-2) Pseudotyped Lentivirus (Luciferase... Artikelnummer: BPS-79942-1
The pandemic coronavirus disease 2019 (COVID-19) is caused by Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2). As the first step of the viral replication, the virus attaches to the host cell surface before entering the cell. The viral Spike protein recognizes and attaches to the Angiotensin-Converting...
| Schlagworte: | 2 |
| Anwendung: | Viral transduction studies, Neutralizing SARS-CoV-2 Spike antibodies screening |
| Reaktivität: | Sars-cov-2 |
ab 1.009,00 €
NEU
Anti-CD19 CAR Lentivirus (CD19 SCFV-CD28-4-1BB-CD3zeta) Artikelnummer: BPS-79851-1
The anti-CD19 CAR lentivirus product is ready-to-use, high titer lentiviral particles of anti-CD19 scFv linked to 3rd generation CAR (Chimeric Antigen Receptor) containing CD28, 4-1BB, and CD3zeta signaling domains. The anti-CD19 CAR Lentivirus can be used to transduce nearly all types of mammalian cells, including...
| Schlagworte: | CD19, B-lymphocyte antigen CD19, Differentiation antigen CD19, T-cell surface antigen Leu-12, B-lymphocyte surface antigen B4 |
| Anwendung: | Primary T cell transduction, CART design specificity, Efficacy, Potency validation, Antibody screening |
| Reaktivität: | Human |
ab 998,00 €
NEU
COVID-19 Forschung
Spike(SARS-CoV-2) Pseudotyped Lentivirus (Luc-eGFP Dual... Artikelnummer: BPS-79982-1
The pandemic coronavirus disease 2019 (COVID-19) is caused by Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2). As the first step of viral replication, the virus attaches to the host cell surface before entering the cell. The viral Spike protein recognizes and attaches to the Angiotensin-Converting...
| Schlagworte: | 2 |
| Anwendung: | Viral transduction mechanism studies, SARS-CoV-2 Spike, ACE2 binding neutralizing antibody screening |
| Reaktivität: | Sars-cov-2 |
ab 1.245,00 €
Firefly Luciferase-eGFP Lentivirus (G418) Artikelnummer: BPS-79980-G
The Firefly Luciferase-eGFP Lentivirus are replication incompetent, HIV-based, VSV-G pseudotyped lentiviral particles that are ready to be transduced into almost all types mammalian cells, including primary and non-dividing cells. These viruses contain a firefly luciferase and eGFP cassette (Luc-P2A-eGFP) driven by...
| Anwendung: | Transduction positive control, Transduction optimization |
998,00 €
FcGRIIIA (CD16a) Lentivirus Artikelnummer: BPS-79876
Fc Gamma Receptor IIIa (FcGRIIIA, FcgammaRIIIA), also known as CD16a, is a low/intermediate affinity receptor for polyvalent immune-complexed IgG. It is involved in phagocytosis, antibody-dependent cytotoxicity and clearance of immune complexes. The human FcgammaRIIIa displays a dimorphism in the position of residue...
| Schlagworte: | CD16a, CD16A, FCGR3A, FcR-10, FcRIII, FcRIIIa, Fc-gamma RIII, CD16a antigen, Fc-gamma RIIIa, Fc-gamma RIII-alpha, IgG Fc... |
| Anwendung: | Transient FcGRIIIA expression, Stable cell line generation |
| Reaktivität: | Human |
1.245,00 €
FcGRIIB (CD32B) Lentivirus Artikelnummer: BPS-79877
Fc Gamma Receptor 2B (FcGR2B, FcgammaRIIB), also known as CD32B, is a 'low affinity' receptor for Immunoglobulin G (IgG). FcGR2B is involved in the phagocytosis of immune complexes and in the regulation of antibody production by B-cells. It is the predominant Fc receptor present on B cells. Crosslinking of...
| Schlagworte: | CD32, CDw32, FCGR2B, FcRII-b, Fc-gamma-RIIb, Fc-gamma RII-b, IgG Fc receptor II-b, Low affinity immunoglobulin gamma Fc... |
| Anwendung: | Transient FcGRIIB expression, Stable cell line generation |
| Reaktivität: | Human |
1.245,00 €
FcER1G Lentivirus Artikelnummer: BPS-79878
FcER1G is an adapter protein containing an immunoreceptor tyrosine-based activation motif (ITAM) that transduces activation signals from various immunoreceptors. As a component of the high-affinity immunoglobulin E (IgE) receptor, FcER1G mediates allergic inflammatory signaling in mast cells. FcER1G is also a...
| Schlagworte: | FCER1G, FcRgamma, FceRI gamma, Fc-epsilon RI-gamma, Fc receptor gamma-chain, IgE Fc receptor subunit gamma, High affinity... |
| Anwendung: | Transient FcER1G expression, Stable cell line generation |
| Reaktivität: | Human |
998,00 €
Firefly Luciferase Lentivirus (UbC Promoter) Artikelnummer: BPS-79880
The Firefly Luciferase Lentivirus are replication incompetent, HIV-based, VSV-G pseudotyped lentiviral particles that are ready to be transduced into almost all types mammalian cells, including primary and non-dividing cells. The particles contain a firefly luciferase gene driven by a UbC (ubiquitin C) promoter. The...
| Schlagworte: | Luciferase, Luciferin 4-monooxygenase |
| Anwendung: | Transduction positive control, Transduction optimization, Stable cell line generation |
| Reaktivität: | Common Eastern Firefly |
998,00 €
AP1 Luciferase Reporter Lentivirus (JNK Signaling Pathway) Artikelnummer: BPS-79823
The stress-activated protein kinase/c-jun N-terminal kinase (SAPK/JNK) family of proteins includes mitogen-activated protein kinases (MAPKs) that are activated by stress, inflammatory cytokines, mitogens, oncogenes, and inducers of cell differentiation and morphogenesis. Upon activation of the SAPK/JNK pathway, MAP...
| Schlagworte: | IFNA2, IFNA2A, LeIF A, IFN-alpha-2, Interferon alpha-2, Interferon alpha-A |
| Anwendung: | JNK signaling pathway activator / inhibitor screening, stable cell line generation |
| Reaktivität: | Human |
998,00 €
ISRE Luciferase Reporter Lentivirus (JAK/STAT Signaling... Artikelnummer: BPS-79824
The JAK/STAT pathway is activated by various cytokines and growth factors and plays a critical role in cell growth, hematopoiesis, and immune response. In mammals, there are four JAKs (JAK1, JAK2, JAK3 and TYK2) and seven STAT proteins. IFNalpha is a Type I interferon. Binding of IFNalpha to its receptor leads to...
| Schlagworte: | IFNA2, IFNA2A, LeIF A, IFN-alpha-2, Interferon alpha-2, Interferon alpha-A |
| Anwendung: | Type I IFN ind. JAK/STAT signaling pathway activator/inhibitor screening, Stable cell line generation |
| Reaktivität: | Human |
998,00 €
TEAD Luciferase Reporter Lentivirus Artikelnummer: BPS-79833
The Hippo pathway regulates cell proliferation and cell death. It is activated by high cell density and cell stress to stop cell proliferation and induce apoptosis. The mammalian Hippo pathway comprises MST kinases and LATS kinases. When the Hippo pathway is activated, MST kinases phosphorylate LATS kinases, which...
| Schlagworte: | TCF13, TEAD1, TEAD-1, NTEF-1, TCF-13, Protein GT-IIC, Transcription factor 13, TEA domain family member 1, Transcriptional... |
| Anwendung: | Hippo pathway activator / inhibitor screening, stable cell line generation |
| Reaktivität: | Human |
998,00 €
ARE Luciferase Reporter Lentivirus Artikelnummer: BPS-79869
The Nrf2 antioxidant response pathway plays an important role in the cellular antioxidant defense. Nrf2, a basic leucine zipper transcription factor, induces the expression of antioxidant and phase II enzymes by binding to the ARE (antioxidant response element) region of the gene promoter. Under basal conditions,...
| Schlagworte: | HEBP1, Nrf-2, NFE2-related factor 2, NF-E2-related factor 2, Nuclear factor, erythroid derived 2, like 2, Nuclear factor... |
| Anwendung: | Nrf2 antioxidant response pathway activator / inhibitor screening, stable cell line generation |
| Reaktivität: | Human |
998,00 €