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COVID-19 Forschung
Spike (SARS-CoV-2) Pseudotyped Lentivirus (Luciferase... Artikelnummer: BPS-79942-1
The pandemic coronavirus disease 2019 (COVID-19) is caused by Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2). As the first step of the viral replication, the virus attaches to the host cell surface before entering the cell. The viral Spike protein recognizes and attaches to the Angiotensin-Converting...
| Schlagworte: | 2 |
| Anwendung: | Viral transduction studies, Neutralizing SARS-CoV-2 Spike antibodies screening |
| Reaktivität: | Sars-cov-2 |
ab 998,00 €
NEU
COVID-19 Forschung
Spike (SARS-CoV-2, UK Variant) Pseudotyped Lentivirus... Artikelnummer: BPS-78112-1
The pandemic coronavirus disease 2019 (COVID-19) is caused by Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2). As the first step of the viral replication, the virus attaches to the host cell surface before entering the cell. The viral Spike protein recognizes and attaches to the Angiotensin-Converting...
| Schlagworte: | 2, B117, B.1.1.7 |
| Anwendung: | Viral transduction studies, Neutralizing SARS-CoV-2 Spike antibodies screening |
| Reaktivität: | Sars-cov-2 |
ab 998,00 €
Anti-CD19 CAR Lentivirus (CD19 SCFV-CD28-4-1BB-CD3zeta) Artikelnummer: BPS-79851-1
The anti-CD19 CAR lentivirus product is ready-to-use, high titer lentiviral particles of anti-CD19 scFv linked to 3rd generation CAR (Chimeric Antigen Receptor) containing CD28, 4-1BB, and CD3zeta signaling domains. The anti-CD19 CAR Lentivirus can be used to transduce nearly all types of mammalian cells, including...
| Schlagworte: | CD19, B-lymphocyte antigen CD19, Differentiation antigen CD19, T-cell surface antigen Leu-12, B-lymphocyte surface antigen B4 |
| Anwendung: | Primary T cell transduction, CART design specificity, Efficacy, Potency validation, Antibody screening |
| Reaktivität: | Human |
ab 998,00 €
COVID-19 Forschung
Spike(SARS-CoV-2) Pseudotyped Lentivirus (Luc-eGFP Dual... Artikelnummer: BPS-79982-1
The pandemic coronavirus disease 2019 (COVID-19) is caused by Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2). As the first step of viral replication, the virus attaches to the host cell surface before entering the cell. The viral Spike protein recognizes and attaches to the Angiotensin-Converting...
| Schlagworte: | 2 |
| Anwendung: | Viral transduction mechanism studies, SARS-CoV-2 Spike, ACE2 binding neutralizing antibody screening |
| Reaktivität: | Sars-cov-2 |
ab 1.245,00 €
COVID-19 Forschung
Spike (SARS-CoV-2) Lentivirus Artikelnummer: BPS-78010-1
Cell entry of SARS-CoV-2 depends on the binding of viral spike protein to cellular receptor ACE2. The SARS-CoV-2 Spike Lentivirus are replication incompetent, HIV-based, VSV-G pseudotyped lentiviral particles that are ready to be transduced into almost all types mammalian cells, including primary and non-dividing...
| Schlagworte: | 2 |
| Anwendung: | Transient knock-down, Stable knock-out cell generation |
| Reaktivität: | Sars-cov-2 |
ab 998,00 €
PD-1 CRISPR/Cas9 Lentivirus (Integrating) Artikelnummer: BPS-78052
The binding of Programmed Cell Death Protein 1 (PD-1), a receptor expressed on activated T-cells, to its ligands, PD-L1 and PD-L2, negatively regulates immune responses. PD-1 ligands are found on most cancers, and the PD-1:PD-L1/2 interaction inhibits T-cell activity and enables cancer cells to escape immune...
| Schlagworte: | hPD-1, CD279, Protein PD-1, Programmed cell death protein 1 |
| Anwendung: | Transient knock-down, Stable knock-out cell generation |
| Reaktivität: | Human |
998,00 €
LAG3 CRISPR/Cas9 Lentivirus (Integrating) Artikelnummer: BPS-78053
Lymphocyte-activation gene 3 (LAG3, CD223) is a cell surface protein that belongs to the immunoglobulin (Ig) superfamily. LAG3 is expressed on activated T-cells, Natural Killer cells, B-cells, and plasmacytoid dendritic cells. Its main ligand is the MHC class II, to which it binds with higher affinity than CD4. It...
| Schlagworte: | FDC |
| Anwendung: | Transient knock-down, Stable knock-out cell generation |
| Reaktivität: | Human |
998,00 €
CTLA4 CRISPR/Cas9 Lentivirus (Integrating) Artikelnummer: BPS-78054
CTLA4 (Cytotoxic T-Lymphocyte Associated Protein), also known as CD152, is a protein receptor that functions as an immune checkpoint. It is expressed by activated T-cells and transmits an inhibitory signal to T-cells. CTLA4 is homologous to the T-cell co-stimulatory protein CD28, and both molecules bind to CD80...
| Schlagworte: | CD152, CTLA4, CTLA-4, Cytotoxic T-lymphocyte protein 4, Cytotoxic T-lymphocyte-associated antigen 4 |
| Anwendung: | Transient knock-down, Stable knock-out cell generation |
| Reaktivität: | Human |
998,00 €
TCR CRISPR/Cas9 Lentivirus (Integrating) Artikelnummer: BPS-78055
The T-Cell Receptor (TCR) is found on the surface of T-cells and is responsible for recognizing antigens bound to MHC (Major Histocompatibility Complex) molecules. Activation of the TCR results in activation of downstream NFAT signaling. The TCR consists of a heterodimer of two different protein chains, of which the...
| Schlagworte: | TCRA, T cell receptor alpha chain constant |
| Anwendung: | Transient knock-down, Stable knock-out cell generation |
| Reaktivität: | Human |
998,00 €
CD47 CRISPR/Cas9 Lentivirus (Integrating) Artikelnummer: BPS-78056
CD47 (also known as Rh-associated protein, GP42, Integrin-Associated Protein (IAP), or Neurophilin) is an immunoglobulin-like protein that interacts with its receptor, Signal-regulatory protein alpha (SIRPalpha), on macrophages. This binding interaction regulates transmigration, oxidative burst cytokine production,...
| Schlagworte: | IAP, CD47, MER6, Protein MER6, Integrin-associated protein, Leukocyte surface antigen CD47, Antigenic surface determinant... |
| Anwendung: | Transient knock-down, Stable knock-out cell generation |
| Reaktivität: | Human |
998,00 €
PD-L1 CRISPR/Cas9 Lentivirus (Integrating) Artikelnummer: BPS-78057
The binding of Programmed Cell Death Protein 1 (PD-1), a receptor expressed on activated T-cells, to its ligands, PD-L1 and PD-L2, negatively regulates immune responses. The PD-1 ligands are found on most cancers, and the PD-1:PD-L1/2 interaction inhibits T-cell activity and allows cancer cells to escape immune...
| Schlagworte: | B7H1, CD274, PD-L1, B7-H1, hPD-L1, B7 homolog 1, PDCD1 ligand 1, Programmed death ligand 1, Programmed cell death 1 ligand 1 |
| Anwendung: | Transient knock-down, Stable knock-out cell generation |
| Reaktivität: | Human |
998,00 €
TIGIT CRISPR/Cas9 Lentivirus (Integrating) Artikelnummer: BPS-78058
TIGIT (T-cell immunoreceptor with Ig and ITIM domains, VSTM3, VSIG9) is a co-inhibitory receptor that is highly expressed in Natural Killer (NK) cells and activated CD4+, CD8+, and regulatory T-cells. Interaction with the Poliovirus Receptor (PVR, CD155) on antigen presenting cells, such as dendritic cells, recruits...
| Schlagworte: | TIGIT, VSIG9, T-cell immunoreceptor with Ig and ITIM domains, V-set and transmembrane domain-containing protein 3, V-set... |
| Anwendung: | Transient knock-down, Stable knock-out cell generation |
| Reaktivität: | Human |
998,00 €