Biochemische Assays

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Pyruvate Assay Kit
Pyruvate Assay Kit

Artikelnummer: Cay700470-96

Pyruvate (pyruvic acid) is a key intermediate in cellular metabolic pathways and is derived primarily from glucose via glycolysis. Abnormal blood pyruvate levels are reported in a number of disorders including shock, liver disease, congestive heart failure, diabetes mellitus, thiamine deficiency, and metabolic...
Schlagworte: Pyruvic Acid Assay Kit
Anwendung: Pyruvate quantification
318,00 €
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Amplite(TM) Fluorimetric Acidic Sphingomyelinase Assay Kit *Red Fluorescence*
Amplite(TM) Fluorimetric Acidic...

Artikelnummer: ABD-13622

Sphingomyelinase (SMase) is an enzyme that is responsible for cleaving sphingomyelin (SM) to phosphocholine and ceramide. Activation of SMases plays an important role in the cellular response such as regulation of cell growth, cell differentiation, cell cycle arrest and programmed cell death. Five types of...
Anwendung: Fluorimetric acidic sphingomyelinase assay
319,00 €
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Amplite(TM) Choline Quantitation Kit
Amplite(TM) Choline Quantitation Kit

Artikelnummer: ABD-40007

Choline and its metabolites play an important role in the structural integrity and signaling of cell membranes and cholinergic neurotransmission (acetylcholine synthesis). It is a major source for methyl groups via its metabolite, trimethylglycine that participates in the S-adenosylmethionine synthesis pathways....
Anwendung: Cholin quantification
211,00 €
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Anthrax Edema Factor Assay Kit
Anthrax Edema Factor Assay Kit

Artikelnummer: Cay18918-96

Anthrax is an infectious disease caused by Bacillus anthracis. The bacterium's pathogenicity results when a tripartite protein toxin is secreted into a host system causing tissue swelling and apoptosis. This toxin is a mixture of three protein components: protective antigen (PA), edema factor (EF), and lethal factor...
Schlagworte: EF, cya, pXO1-122, EC=4.6.1.1, Edema factor, Adenylyl cyclase, ATP pyrophosphate-lyase, Calmodulin-sensitive adenylate...
1.219,00 €
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Cyclic AMP TR-FRET Kit
Cyclic AMP TR-FRET Kit

Artikelnummer: Cay23042-1

The TR-FRET cAMP Assay is designed to allow the user to detect and quantitatively measure the amount of cyclic AMP (cAMP) present in cell based assay systems. A europium (Eu) labeled monoclonal anti-cAMP antibody (Donor) is paired with a fluorescently labeled cAMP analog (Acceptor), and in the absence of any...
Schlagworte: Adenosine 3',5'-cyclic mononucleotide, Adenosine 3',5'-cyclic monophosphate, cAMP TR-FRET
Anwendung: ELISA
499,00 €
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Creatinine (urinary) Colorimetric Assay Kit
Creatinine (urinary) Colorimetric Assay Kit

Artikelnummer: Cay500701-96

Creatine is synthesized in kidney, liver, and pancreas and transported to muscle and brain where it is phosphorylated to phosphocreatine. Some free creatine in muscle is converted to creatinine. The amount of creatinine produced is proportional to an individual's muscle mass. In the absence of renal disease, the...
Anwendung: Creatinine measurement
ab 102,00 €
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COX (ovine) Inhibitor Screening Assay Kit
COX (ovine) Inhibitor Screening Assay Kit

Artikelnummer: Cay560101-96

The COX (ovine) Inhibitor Screening Assay directly measures PGF2alpha produced in the cyclooxygenase reaction. The prostanoid product is quantified via enzyme immunosorbent assay (ELISA) using a broadly specific antibody that binds to all the major prostaglandin compounds. Thus, this Cayman COX assay is more...
Anwendung: COX inhibitor screening
469,00 €
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COX (ovine/human) Inhibitor Screening Assay Kit
COX (ovine/human) Inhibitor Screening Assay Kit

Artikelnummer: Cay560131-96

Cyclooxygenase (COX, also called Prostaglandin H Synthase or PGHS) enzymes contain both cyclooxygenase and peroxidase activities. COX catalyzes the first step in the biosynthesis of prostaglandins (PGs), thromboxanes, and prostacyclins, the conversion of arachidonic acid to PGH2. It is now well established that...
Anwendung: COX inhibitor screening
469,00 €
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Prostaglandin D Synthase (hematopoietic-type) FP-Based Inhibitor Screening Assay Kit - Green
Prostaglandin D Synthase (hematopoietic-type)...

Artikelnummer: Cay600007-384

Prostaglandin D2 (PGD2) is synthesized by hematopoietic-type PGD-synthase (H-PGDS) in mast cells and is released in large quantities during allergic and asthmatic anaphylaxis. H-PGDS is therefore a key target for development of selective, potent inhibitors for therapeutic use against these diseases. Cayman's H-PGDS...
Schlagworte: GSTS, HPGDS, H-PGDS, EC=2.5.1.18, EC=5.3.99.2, GST class-sigma, Glutathione S-transferase, Prostaglandin-H2 D-isomerase,...
Anwendung: PGDS inhibitor screening
Reaktivität: Human
ab 445,00 €
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p53 Transcription Factor Assay Kit
p53 Transcription Factor Assay Kit

Artikelnummer: Cay600020-96

The tumor suppressor protein p53 plays a crucial role in coordinating cellular responses to genotoxic stress and holds many important clinical implications in the treatment of cancer. Cayman's p53 Transcription Factor Assay is a non-radioactive, sensitive method for detecting specific transcription factor DNA...
Schlagworte: P53, TP53, Antigen NY-CO-13, Phosphoprotein p53, Tumor suppressor p53, Cellular tumor antigen p53
Anwendung: P53 detection
532,00 €
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SET7/9 SAM-Screener(TM) Assay Kit
SET7/9 SAM-Screener(TM) Assay Kit

Artikelnummer: Cay600490-384

Most histone lysine methyltransferases contain a conserved domain (SET) that utilizes S-adenosyl-L-methionine (SAM or AdoMet) as a co-factor to catalyze the methylation of lysine. SET7/9 (KMT7) is a SET domain-containing mono-methyltransferase that acts on a large number of histone and non-histone targets including...
Schlagworte: SETD7, SET7/9, KIAA1717, EC=2.1.1.43, H3-K4-HMTase SETD7, Lysine N-methyltransferase 7, SET domain-containing protein 7,...
Anwendung: Fluorescence, HTS
ab 469,00 €
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GLP SAM-Screener(TM) Assay Kit
GLP SAM-Screener(TM) Assay Kit

Artikelnummer: Cay600570-384

Most histone lysine methyltransferases contain a conserved domain (SET) that utilizes S-adenosyl-L-methionine (SAM or AdoMet) as a co-factor to catalyze the methylation of the epsilon amino group of lysine. G9a-like protein (GLP) is a SET domain-containing methyltransferase that specifically mono- and di-methylates...
Schlagworte: GLP, GLP1, EHMT1, EUHMTASE1, Eu-HMTase1, EC=2.1.1.-, EC=2.1.1.43, H3-K9-HMTase 5, G9a-like protein 1, Lysine...
Anwendung: Fluorescence, HTS
ab 469,00 €
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