Produkte von BPS

BPS

Sonne, Meer und Wissenschaft: BPS Bioscience aus San Diego stellt rekombinante Histon-Deacetylasen, Methyltransferasen und Demethylasen sowie weitere Modifikationsenzyme her. BPS hat außerdem eine große Auswahl an Enzymen und Proteinen für die Wirkstoff- sowie die Immuntherapie-Forschung im Programm.

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Anti-GST-like protein, clone 1C7
Anti-GST-like protein, clone 1C7

Artikelnummer: BPS-25014

Recognizes GST-like protein from insect Sf9 cells (Spodoptera frugiperda). No cross-reaction with GST tag from S. japonicum or GST fusion proteins. Immunogen: Full length S. frugiperda GST-like protein, purified from Sf9 cells. Applications: IP, Removal of contaminating GST-like protein from insect expressed...
Anwendung: IP
329,00 €
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Anti-5 hmC  (rabbit)
Anti-5 hmC (rabbit)

Artikelnummer: BPS-25204

5 hydroxymethylcytosine (5 hmC) results from the enzymatic conversion of 5 methylcytosine into 5 hydroxymethylcytosine by the TET family of iron dependent oxygenases. 5 hmC bases were recently discovered in mammalian DNA, in Purkinje neurons, in granule cells and embryonic stem cells where theyare present at high...
Schlagworte: Anti-5 hydroxymethylcytosine, Anti-5-hydroxymethyl-cytosine
Anwendung: HMeDIP, ELISA, Dot Blot
389,00 €
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Anti-5 mC, clone 33D3
Anti-5 mC, clone 33D3

Artikelnummer: BPS-25206

The 5 methylcytosine antibody (clone 33D3) is the most published and widely used antibody for DNA methylation analysis. It has been validated for Methylated DNA Immunoprecipitation (MeDIP seq, MeDIP on chip), Immunofluorescence, Flow Cytometry, Dot blot & ELISA.
Schlagworte: Anti-5 hydroxymethylcytosine, Anti-5-hydroxymethyl-cytosine
Anwendung: MeDIP, ELISA, Dot Blot, IF, FISH, Southern blot
389,00 €
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DNA Polymerase Beta (POLB), human recombinant protein, N-terminal His-tag
DNA Polymerase Beta (POLB), human recombinant...

Artikelnummer: BPS-21000-2

Human DNA polymerase beta, also known as Pol beta and POLB (GenBank Accession No. NM_002690), amino-acids 2-335 (end), with N-terminal His-tag, MW=39 kDa, expressed in an E. coli cell expression system.
Schlagworte: POLB, EC=2.7.7.7, EC=4.2.99.-, DNA polymerase beta
Anwendung: DNA synthesis, DNA repair, As an antigen for Western blotting, For inhibitor screening
Reaktivität: Human
MW: 39 kD
ab 443,00 €
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BAM7
BAM7

Artikelnummer: BPS-27607-2

BAM7 is a direct and selective activator of BAX with IC50 value of 3.3 µM.
Schlagworte: BAM 7, BAM-7, (4E)-4-[(2-ethoxyphenyl)hydrazinylidene]-5-methyl-2-(4-phenyl-1,3-thiazol-2-yl)pyrazol-3-one
Anwendung: Bax inhibitor
MW: 405.5 D
ab 344,00 €
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CDK6, His-Tag
CDK6, His-Tag

Artikelnummer: BPS-100031

Human CDK6, also known as Cell division protein kinase 6, MCPH12, and PLSTIRE GenBank Accession No. NM_001259, a.a. 2-end, expressed in a Baculovirus infected Sf9 expression system. MW = 38 kDa.
Schlagworte: CDK6, CDKN6, EC=2.7.11.22, Cyclin-dependent kinase 6, Cell division protein kinase 6, Serine/threonine-protein kinase PLSTIRE
Anwendung: Kinase
Reaktivität: Human
MW: 38 kD
450,00 €
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CTLA4 (Woodchuck), Fc-Fusion (Human), Avi-tag HiP(TM)
CTLA4 (Woodchuck), Fc-Fusion (Human), Avi-tag...

Artikelnummer: BPS-100037

Woodchuck secreted CTLA4, also known as Cytotoxic T-lymphocyte-associated protein 4 and CD152, with N-terminal Avi-TagTM fused to the Fc region of Human IgG1, a.a. 36-162 expressed in a HEK293 cell expression system. MW = 42 kDa (monomer). This protein runs at a higher MW by SDS-PAGE due to glycosylation.
Schlagworte: Cytotoxic T-lymphocyte associated antigen 4
Anwendung: Immunotherapy studies
Reaktivität: Woodchuck
MW: 42+ kD
405,00 €
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B7-1 (Woodchuck), Fc-fusion (Human), Avi-Tag, Biotin-labeled
B7-1 (Woodchuck), Fc-fusion (Human), Avi-Tag,...

Artikelnummer: BPS-100040

Woodchuck B7-1, also known as CD80, with C-terminal Avi-Tag fused to the Fc-region of Human IgG1. a.a 30-237, expressed in a HEK293 cell expression system and enzymatically biotin-labeled using Avi-tag(TM) technology. MW = 52 kDa. This protein runs at a higher M.W. by SDS-PAGE due to glycosylation.
Schlagworte: CD80 molecule
Anwendung: Immunotherapy studies
Reaktivität: Woodchuck
MW: 52+ kD
551,00 €
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BTLA, Fc Fusion, Avi-Tag, Biotin-Labeled
BTLA, Fc Fusion, Avi-Tag, Biotin-Labeled

Artikelnummer: BPS-100047

Human B- and T-lymphocyte attenuator BTLA, also known as CD272, GenBank Accession No. NM_181780, a.a. 31-150, with C-terminal Avi-Tag fused to the Fc region of Human IgG1, expressed in a HEK293 cell expression system. MW = 42 kDa (monomer). This protein is enzymatically biotinylated using Avi-TagTM technology.
Schlagworte: BTLA, CD272, B- and T-lymphocyte attenuator, B- and T-lymphocyte-associated protein
Anwendung: Immunotherapy studies
Reaktivität: Human
MW: 42 kD
551,00 €
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Droxinostat
Droxinostat

Artikelnummer: BPS-27620-2

Droxinostat is a selective inhibitor of HDAC, mostly for HDACs 6 and 8 with IC50 of 2.47 ?M and 1.46 ?M, greater than 8-fold selective against HDAC3 and no inhibition to HDAC1, 2, 4, 5, 7, 9, and 10.
Schlagworte: NS 41080, 4-(4-Chloro-2-methylphenoxy)-N-hydroxybutanamide
Anwendung: HDAC6/8 inhibitor
MW: 243.7 D
ab 281,00 €
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Entacapone
Entacapone

Artikelnummer: BPS-27621-2

Entacapone is a second-generation catechol-O-methyltransferase (COMT) inhibitor
Schlagworte: (E)-2-cyano-3-(3,4-dihydroxy-5-nitrophenyl)-N,N-diethylprop-2-enamide
Anwendung: COMT inhibitor
MW: 305.3 D
ab 208,00 €
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EPZ-6438
EPZ-6438

Artikelnummer: BPS-27626-3

EPZ-6438 is a potent and bio-available inhibitor of EZH2, the catalytic subunit of polycomb repressive complex 2 (PRC2) catalyzing the methylation of lysine 27 of histone H3 (H3K27), that inhibits the activity of human PRC2-containing wild-type EZH2 (Ki = 2.5 nM).
Schlagworte: E-7438,...
Anwendung: EZH2 inhibitor
MW: 572.7 D
ab 353,00 €
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