Produkte von South Bay Bio

South Bay Bio

South Bay Bio ist ein Biotechnologieunternehmen, das sich auf die Herstellung von Hochdurchsatz-Screening-Produkten mit Schwerpunkt auf dem Ubiquitin-Proteasom-System spezialisiert hat. Das Unternehmen wurde in der San Francisco Bay Area gegründet, um dort ansässige Biotechnologie-Unternehmen zu unterstützen. Das Firmensitz befindet sich in der Stadt San Jose.

Mehr unter: southbaybio.com

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COVID-19 Forschung
PLpro (SARS Coronavirus) (rec.) (His)
PLpro (SARS Coronavirus) (rec.) (His)

Artikelnummer: SBB-DE0024-C050

The severe acute respiratory syndrome coronavirus papain-like protease (SARS-CoV PLpro) is involved in the processing of the viral polyprotein. Proteolytic processing of the coronavirus replicase poly-protein is essential for generating a functional virus replication complex. PLpro possesses both deubiquitinating or...
Schlagworte: Papain-like Proteinase, SARS Coronavirus Main Proteinase, Non-structural Protein 3, PL2-PRO, Nsp3
Anwendung: Assays
Reaktivität: Sars-cov
MW: 37 kD
212,00 €
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ITCH E3 Ligase TR-FRET Kit
ITCH E3 Ligase TR-FRET Kit

Artikelnummer: SBB-KF0035-KI01

South Bay Bio's ITCH TR-FRET Ubiquitin Kit provides a fast and sensitive method monitoring ubiquitin conjugation onto ITCH in solution, resulting from an enzymatic ubiquitin cascade without the need of running and staining an SDS gel. The kit enables continuous TR-FRET detection of ubiquitin chain formation onto...
Schlagworte: Itch, ITCH, AIP4, NAPP1, EC=2.3.2.26, NFE2-associated polypeptide 1, Atrophin-1-interacting protein 4, E3...
Anwendung: Enzyme assays
Reaktivität: Human
847,00 €
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Ubiquitin aldehyde (human) (rec.)
Ubiquitin aldehyde (human) (rec.)

Artikelnummer: SBB-PS0031-C050

Ubiquitin is a small (8.5kDa) regulatory protein that has been found in almost all tissues of eukaryotic organisms. The addition of ubiquitin to a substrate protein is called ubiquitination or ubiquitylation. Ubiquitination can affect proteins in many ways: it can signal for their degradation via the proteasome,...
Anwendung: Assays
Reaktivität: Human
MW: 9 kD
135,00 €
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Ubiquitin Activating Enzyme E1 [UBE1] (human) (rec.) (untagged)
Ubiquitin Activating Enzyme E1 [UBE1] (human) (rec.)...

Artikelnummer: SBB-CE0011-C050

UBA1, the canonical ubiquitin E1 activating enzyme is a 118kDa protein, which forms a homodimer in its active state and catalyzes the first step of the ubiquitin conjugation cascade. It activates ubiquitin in an ATP-dependent mechanism where ATP is hydrolyzed to AMP and PPi, a ubiquitin C-terminal adenylate...
Schlagworte: Ubiquitin E1 Enzyme, Ubiquitin-like Modifier-activating Enzyme 1, A1S9T, AMCX1, GXP1, POC20, SMAX2
Anwendung: Assays
Reaktivität: Human
MW: 118 kD
270,00 €
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UbcH5a [UBE2D1] (human) (rec.) (untagged)
UbcH5a [UBE2D1] (human) (rec.) (untagged)

Artikelnummer: SBB-CE0021-C100

UBE2D1 (UbcH5a) is an E2 ubiquitin conjugating enzyme. An E1 activating enzyme is required to attach ubiquitin to UBE2D1 via an active site cysteine. The mechanism of ubiquitin transfer involves the breaking of a E1-Ub thioester linkage, followed by a reformation of a UBE2D1-Ub thioester. UBE2D1 is capable of...
Schlagworte: Ubiquitin-conjugating Enzyme H5a, PUBC1, UBC5A, Ubiquitin-protein Ligase D1, p53-regulated Ubiquitin-conjugating Enzyme 1
Anwendung: Assays
Reaktivität: Human
MW: 17 kD
255,00 €
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20S Proteasome (human) (untagged)
20S Proteasome (human) (untagged)

Artikelnummer: SBB-PP0005-C050

The ubiquitin-proteasome pathway is the major proteolytic system in eukaryotic cells, where it catalyzes the selective degradation of short-lived regulatory proteins or the rapid turnover of misfolded proteins. One of the most important proteases in this pathway is the 26S proteasome, an ATP-dependent proteolytic...
Anwendung: Assays
Reaktivität: Human
MW: 700 kD
198,00 €
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Ubiquitin (human) (rec.) (untagged)
Ubiquitin (human) (rec.) (untagged)

Artikelnummer: SBB-UP0013-M010

Ubiquitin is a 76 amino acid post-translational modifier expressed throughout all tissues in eukaryotic organisms. The many roles of ubiquitin modification include proteasomal degradation, signal transduction, inflammatory response and DNA damage repair. Ubiquitin modification occurs through a pyramidal cascade of...
Schlagworte: UBB, Ubiquitin B
Anwendung: Assays
Reaktivität: Human
MW: 9 kD
84,00 €
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Mdm2 E3 Ligase TR-FRET Kit
Mdm2 E3 Ligase TR-FRET Kit

Artikelnummer: SBB-KF0030-KI01

South Bay Bio's MDM2 TR-FRET Ubiquitin Kit provides a fast and sensitive method monitoring ubiquitin conjugation onto GST-MDM2 in solution, resulting from an enzymatic ubiquitin cascade without the need of running and staining an SDS gel. The kit enables continuous TR-FRET detection of ubiquitin chain formation onto...
Schlagworte: MDM2, Hdm2, EC=2.3.2.27, Oncoprotein Mdm2, Double minute 2 protein, p53-binding protein Mdm2, E3 ubiquitin-protein ligase...
Anwendung: Enzyme assays
Reaktivität: Human
847,00 €
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NEDD8 (human) (rec.) (Rhodamine 110)
NEDD8 (human) (rec.) (Rhodamine 110)

Artikelnummer: SBB-PS0003-C050

NEDD8 (Neural Precursor Cell Expressed, Developmentally Down-Regulated 8) is a ubiquitin like protein that plays an important role in regulating development and the cell cycle. NEDD8 is conjugated to a target protein via a signaling cascade similar to ubiquitin: a NEDD8 specific E1 activating enzyme (APPBP1/UBA3)...
Schlagworte: Neural Precursor Cell Expressed Developmentally Down-Regulated Protein 8, Neddylin, Rub1
Anwendung: Assays
Reaktivität: Human
MW: 9 kD
327,00 €
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Ubiquitin (human) (rec.) (Cy5)
Ubiquitin (human) (rec.) (Cy5)

Artikelnummer: SBB-TR0015-C050

Ubiquitin is a highly conserved protein that plays a major role in the ubiquitination pathway, which is conserved from yeast to mammals. Ubiquitination, the conjugation of ubiquitin to other proteins through a covalent bond between its C-terminal glycine and the epsilon-amino group of lysine residues or the...
Schlagworte: UBB, Ubiquitin B
Anwendung: Assays
Reaktivität: Human
MW: 9 kD
212,00 €
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20S Constitutive Proteasome Assay Kit
20S Constitutive Proteasome Assay Kit

Artikelnummer: SBB-KP0038-KI01

South Bay Bio's kit is designed to test for specific activity of 20S proteasome. The kit provides purified 20S proteasome and is designed to test for Chymotrypsin-like activity (Suc-LLVY-AMC), Caspase-like activity of the proteasome subunits beta1/PSMB6 (LLE-AMC) and Chymotrypsin-like activity of beta5/PSMB5...
Anwendung: Compound Screening
420,00 €
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HA-Ubiquitin-vinyl methyl ester (human) (rec.) (HA)
HA-Ubiquitin-vinyl methyl ester (human) (rec.) (HA)

Artikelnummer: SBB-PS0123-C050

Protein. Human ubiquitin (aa1-76) (Accession Nr. P0CG47) with a C-terminal vinyl methyl ester group and a N-terminal HA-Tag. Source: E. coli. Liquid. In 50mM MES pH 6.0, 100mM sodium chloride. Purity: >97% (LCMS). Ubiquitin is a small (8.5kDa) regulatory protein that has been found in almost all tissues of...
Schlagworte: HA-Ub-VME, HA-Ubiquitin-VME, HA-Ubiquitin-Vinyl methyl ester
Reaktivität: Human
MW: 10 kD
277,00 €
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