Produkte von South Bay Bio

South Bay Bio

South Bay Bio ist ein Biotechnologieunternehmen, das sich auf die Herstellung von Hochdurchsatz-Screening-Produkten mit Schwerpunkt auf dem Ubiquitin-Proteasom-System spezialisiert hat. Das Unternehmen wurde in der San Francisco Bay Area gegründet, um dort ansässige Biotechnologie-Unternehmen zu unterstützen. Das Firmensitz befindet sich in der Stadt San Jose.

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Ubiquitin Activating Enzyme E1 [UBE1] (human) (rec.) (untagged)
Ubiquitin Activating Enzyme E1 [UBE1] (human) (rec.)...

Artikelnummer: SBB-CE0011-C050

UBA1, the canonical ubiquitin E1 activating enzyme is a 118kDa protein, which forms a homodimer in its active state and catalyzes the first step of the ubiquitin conjugation cascade. It activates ubiquitin in an ATP-dependent mechanism where ATP is hydrolyzed to AMP and PPi, a ubiquitin C-terminal adenylate...
Schlagworte: Ubiquitin E1 Enzyme, Ubiquitin-like Modifier-activating Enzyme 1, A1S9T, AMCX1, GXP1, POC20, SMAX2
Anwendung: Assays
Reaktivität: Human
MW: 118 kD
274,00 €
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UbcH5c [UBE2D3] (human) (rec.) (untagged)
UbcH5c [UBE2D3] (human) (rec.) (untagged)

Artikelnummer: SBB-CE0019-C100

UBE2D3 [UbcH5c] is an E2 ubiquitin conjugating enzyme. An E1 activating enzyme is required to attach ubiquitin to UBE2D3 via an active site cysteine. The mechanism of ubiquitin transfer involves the breaking of a E1-Ub thioester linkage, followed by a reformation of a UBE2D3-Ub thioester. UBE2D3 is capable of...
Schlagworte: Ubiquitin-conjugating Enzyme H5c, PUBC, UBC5C, Ubiquitin-protein Ligase D3, p53-regulated Ubiquitin-conjugating Enzyme
Anwendung: Assays
Reaktivität: Human
MW: 17 kD
260,00 €
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UbcH7 [UBE2L3] (human) (rec.) (untagged)
UbcH7 [UBE2L3] (human) (rec.) (untagged)

Artikelnummer: SBB-CE0020-C100

UBE2L3 (UbcH7) is an E2 ubiquitin conjugating enzyme and accepts ubiquitin from an E1 activating enzyme via an active site cysteine. The mechanism of ubiquitin transfer involves the breaking of a E1-Ub thioester linkage, followed by a reformation of a UBE2L3-Ub thioester. UBE2L3 transfers active ubiquitin molecules...
Schlagworte: Ubiquitin-conjugating Enzyme E2 L3, E2-F1, L-UBC, UBCE7, UbcM4, UBE2L3, Ubiquitin-protein Ligase L3
Anwendung: Assays
Reaktivität: Human
MW: 18 kD
260,00 €
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UbcH5a [UBE2D1] (human) (rec.) (untagged)
UbcH5a [UBE2D1] (human) (rec.) (untagged)

Artikelnummer: SBB-CE0021-C100

UBE2D1 (UbcH5a) is an E2 ubiquitin conjugating enzyme. An E1 activating enzyme is required to attach ubiquitin to UBE2D1 via an active site cysteine. The mechanism of ubiquitin transfer involves the breaking of a E1-Ub thioester linkage, followed by a reformation of a UBE2D1-Ub thioester. UBE2D1 is capable of...
Schlagworte: Ubiquitin-conjugating Enzyme H5a, PUBC1, UBC5A, Ubiquitin-protein Ligase D1, p53-regulated Ubiquitin-conjugating Enzyme 1
Anwendung: Assays
Reaktivität: Human
MW: 17 kD
260,00 €
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UbcH1 [UBE2K, E2-25K] (human) (rec.) (His)
UbcH1 [UBE2K, E2-25K] (human) (rec.) (His)

Artikelnummer: SBB-CE0022-C100

UBE2K (UbcH1) is an E2 ubiquitin conjugating enzyme. An E1 activating enzyme is required to attach ubiquitin to UBE2K via an active site cysteine. The mechanism of ubiquitin transfer involves the breaking of a E1-Ub thioester linkage, followed by a reformation of a UBE2K-Ub thioester. UBE2K is capable of...
Schlagworte: Ubiquitin-conjugating Enzyme E2, E2-25K, Hip2, HYPG, LIG, UBE2K, UBE2K-25K, Huntingtin-interacting Protein 2
Anwendung: Assays
Reaktivität: Human
MW: 22 kD
260,00 €
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UbcH5b [UBE2D2] (human) (rec.) (untagged)
UbcH5b [UBE2D2] (human) (rec.) (untagged)

Artikelnummer: SBB-CE0027-C100

UBE2D2 (UbcH5b) is an E2 ubiquitin conjugating enzyme. An E1 activating enzyme is required to attach ubiquitin to UBE2D2 via an active site cysteine. The mechanism of ubiquitin transfer involves the breaking of a E1-Ub thioester linkage, followed by a reformation of a UBE2D2-Ub thioester. UBE2D2 is capable of...
Schlagworte: Ubiquitin-conjugating Enzyme H5b, PUBC1, UBC5B, Ubiquitin-protein Ligase D2, p53-regulated Ubiquitin-conjugating Enzyme 1
Anwendung: Assays
Reaktivität: Human
MW: 17 kD
224,00 €
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UcH-L3 (human) (rec.) (untagged)
UcH-L3 (human) (rec.) (untagged)

Artikelnummer: SBB-DE0023-C050

UCHL3 (Ubiquitin C-terminal Hydrolase L3) is a deubiquitinating enzyme (DUB) that controls levels of cellular ubiquitin through processing of ubiquitin precursors and ubiquitinated proteins. It is a thiol protease that recognizes and hydrolyzes a peptide bond at the C-terminal glycine of either ubiquitin or NEDD8....
Schlagworte: Ubiquitin C-terminal Hydrolase L3, Ubiquitin Thioesterase L3
Anwendung: Assays
Reaktivität: Human
MW: 26 kD
162,00 €
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PLpro (SARS Coronavirus) (rec.) (His)
PLpro (SARS Coronavirus) (rec.) (His)

Artikelnummer: SBB-DE0024-C050

The severe acute respiratory syndrome coronavirus papain-like protease (SARS-CoV PLpro) is involved in the processing of the viral polyprotein. Proteolytic processing of the coronavirus replicase poly-protein is essential for generating a functional virus replication complex. PLpro possesses both deubiquitinating or...
Schlagworte: Papain-like Proteinase, SARS Coronavirus Main Proteinase, Non-structural Protein 3, PL2-PRO, Nsp3
Anwendung: Assays
Reaktivität: Sars-cov
MW: 37 kD
217,00 €
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NEDP1 [SENP8] (human) (rec.) (His)
NEDP1 [SENP8] (human) (rec.) (His)

Artikelnummer: SBB-DE0025-C050

NEDP1 is a deconjugating enzyme with specificity towards NEDDylated substrates. NEDP1 discriminates between ubiquitinated and NEDDylated targets, despite similar C-terminal regions. NEDP1 is a protease which hydrolyzes the isopeptide bond between the C-terminus of NEDD8 and the respective lysine of the substrate...
Schlagworte: NEDD8-specific Protease 1, Sentrin-specific Protease 8, Deneddylase-1, Sentrin/SUMO-specific Protease SENP8, DEN1, PRSC2
Anwendung: Assays
Reaktivität: Human
MW: 27 kD
162,00 €
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SENP1 (catalytic domain) (human) (rec.) (His)
SENP1 (catalytic domain) (human) (rec.) (His)

Artikelnummer: SBB-DE0026-C050

SUMO/Sentrin Specific Peptidase 1 (SENP1) is a member of the SENP family of proteases, which belong to the group of cysteine-­type peptidases. SENP1 is a SUMO-specific enzyme that catalyzes two essential functions. Processing the full-length versions of SUMO1, SUMO2 and SUMO3 into its mature forms and the...
Schlagworte: Sentrin-specific Protease 1, Sentrin/SUMO-specific Protease SENP1
Anwendung: Assays
Reaktivität: Human
MW: 32 kD
162,00 €
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Mdm2 E3 Ligase TR-FRET Kit
Mdm2 E3 Ligase TR-FRET Kit

Artikelnummer: SBB-KF0030-KI01

South Bay Bio's MDM2 TR-FRET Ubiquitin Kit provides a fast and sensitive method monitoring ubiquitin conjugation onto GST-MDM2 in solution, resulting from an enzymatic ubiquitin cascade without the need of running and staining an SDS gel. The kit enables continuous TR-FRET detection of ubiquitin chain formation onto...
Schlagworte: MDM2, Hdm2, EC=2.3.2.27, Oncoprotein Mdm2, Double minute 2 protein, p53-binding protein Mdm2, E3 ubiquitin-protein ligase...
Anwendung: Enzyme assays
Reaktivität: Human
746,00 €
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ITCH E3 Ligase TR-FRET Kit
ITCH E3 Ligase TR-FRET Kit

Artikelnummer: SBB-KF0035-KI01

South Bay Bio's ITCH TR-FRET Ubiquitin Kit provides a fast and sensitive method monitoring ubiquitin conjugation onto ITCH in solution, resulting from an enzymatic ubiquitin cascade without the need of running and staining an SDS gel. The kit enables continuous TR-FRET detection of ubiquitin chain formation onto...
Schlagworte: Itch, ITCH, AIP4, NAPP1, EC=2.3.2.26, NFE2-associated polypeptide 1, Atrophin-1-interacting protein 4, E3...
Anwendung: Enzyme assays
Reaktivität: Human
746,00 €
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