Kataloge von AdipoGen Life Sciences

Advanced Immune Regulation Reagents - 3rd Edition

AdipoGen Life Sciences offers a comprehensive panel of new and innovative products in the Immune-Regulation Research Field. This flyer gives an overview on unqiue and the newest antibodies, proteins, ELISA kits and small molecules developed by AdipoGen Life Sciences. Updated September 2019.


Neuroscience Research - 3rd Edition

AdipoGen offers a broad range of unique tools for neuroinflammation and neurodegeneration research. This includes biologically active Netrin-1 for axon outgrowth studies, the best inflammasomes research reagents to study the activation of neuroinflammation, biologically active Notch ligands, unique progranulin ELISA Kits and proteins, a broad range of adiponectin reagents, many Neurochemicals (including Gangliosides) and a unique polyglutamylation antibody. Updated September 2019.


Innate Immunity - Focus Toll-like Receptors (TLR) Agonists - 2nd Edition

  • TLR Receptors Agonists: TLR1/TLR2; TLR3; TLR4/CD14; TLR5; TLR6/TLR12; TLR7; TLR7/8; TLR9; TLR11/12
  • RIG-I-like Receptors & Cytosolic DNA Sensor Agonists: MDA5; STING
  • TLR4 and TLR9 Antagonists: IAXO Compounds; iODNs
  • NLRC3 – Negative Regulator of Innate Immunity.

Updated September 2019.


Immune Checkpoint Reagents: Focus on T Cells

Cancer immunotherapy (also called immuno-oncology) is the artificial stimulation of the immune system to treat cancer, improving on the system's natural ability to fight cancer. Immune checkpoints are regulators of the immune system. These pathways are crucial for self-tolerance, which prevents the immune system from attacking cells indiscriminately. Inhibitory checkpoint molecules, such as CTLA-4, PD-1, PD-L1 or LAG-3 are targets for cancer immunotherapy due to their potential for use in multiple types of cancers.  AdipoGen Life Sciences offers a broad panel immune checkpoint reagents, including recombinant proteins, antibodies and ELISA Kits. Released March 2019.


Rare Biologically Active Antibiotics & Mycotoxins

AdipoGen Life Sciences offers a broad panel of >500 natural products, from bacterial, fungal, marine and plant sources. This panel includes known active and well characterized natural products in combination with unusual and difficult to isolate compounds, which are unique to AdipoGen Life Sciences. All compounds are structurally determined, purified and analytically validated. Included in this panel a key standard research antibiotics, rare metabolites/antibiotics with new chemical structures (often only described once in literature and afterwards lost to research) or old already forgotten substances for lead drug research, seeking new “antibiotics” with new mode of actions and new molecular targets. Released October 2018.


Immunometabolism Research - Focus Cell Metabolism & NAD+ Metabolism

AdipoGen Life Sciences offer a broad range of Cell Metabolism and NAD+ Metabolism Reagents:

  • Small Molecules Modulators of Glycolysis, TCA Cycle, Fatty Acid Oxidation, Fatty Acid Synthesis Pathway, Amino Acid Pathways
  • Inhibitors of IDO1 and Nampt
  • Biologically active enzymes: Human Arginase I / Human IDO1 Enzyme / Mouse Nampt

This brochure includes a cell metabolism signaling wallchart with relevant small molecule inhibitors. Released July 2018.


Inflammasome Research - From Innate to Adaptive Immunity - 2nd Edition

  • Caspase-1 Detection
  • Standard Antibodies
  • Signaling Chart
  • Priming
  • Microtubule Assembly
  • Inhibitors/Activators
  • Flagellin

Released June 2018.


Functional Antibodies - 3rd Edition

Antibodies displaying an agonist or antagonist activity (functional grade antibodies (FuncAbs™)) are powerful tools for mimicking or blocking physiological functions in vitro and in vivo. Adipogen Life Sciences offers functional grade antibodies free of preservatives and tested for low endotoxin content and useful for activation, neutralizing or blocking studies, both in vitro or in vivo. Adipogen Life Sciences also offers recombinant monoclonal antibodies (RecMAbs™) generated by antibody phage display. An important attribute of the RecMAbs™ phage display approach is the ability to design selection strategies to generate antibodies with customized functions (FuncAbs™). Released February 2018.


Interleukin-36gamma - An Important Biomarker for Psoriasis

The proinflammatory cytokine IL-36gamma is highly expressed in skin epithelial cells and in several myeloid-derived cell types. IL-36gamma is a pivotal mediator of epithelial inflammation and is strongly associated with the inflammatory skin disease psoriasis. Released November 2017.


Obesity & Diabetes Research

Focus: White & Brown Fat Cells as Endocrine Tissues.

  • KEY Adipokines
  • Obesity & Immunometabolism
  • IL-33 & Adipose Tissue Homeostasis
  • Obesity & Angiogenesis
  • WAT Browning
  • Myokines
  • Small Molecule Modulators

Updated October 2017.


ELISA Kits for Key Biomarkers

AdipoGen Life Sciences Biomarkers Assays: Adiponectin | ANGPTL3 | ANGPTL6 | BAFF | Caspase-1 | DLK1 | GPX1 | GPX3 | IL-1α | IL-33 | IL-36β | IL-36γ | IL-36Ra | IL-37 | IL-38 | Irisin | Lipocalin-2 | Nampt/Visfatin | Periostin | Progranulin | RBP4 | RELM-β | Resistin | Sirtuin 1 | Vaspin | Zinc-α Glycoprotein

Also included are the CyMAX™ Cytokine Assays from Abfrontier and the Oxidative Stress Assays from JaICA. Updated June 2017.


Notch Signaling Pathway

  • Notch Receptors Notch1 & Notch2 Antibodies & Proteins
  • Canonical Notch Ligands: DLL1, DLL3, DLL4, Jagged-1 and -2 Antibodies & Proteins
  • Non-classical Notch Ligands: DLK1 and DLK2 Antibodies, Proteins and ELISA Kit
  • Non-confirmed Notch Ligand: DNER Antibodies & Proteins
  • Notch Target Hes1
  • E3UBLs and DUBs
  • ADAM17 Blocking Antibody
  • Notch Processing/g-Secretase Inhibitors

Released May 2017.


Zuletzt angesehen