Lipide

Lipide sind kleine organische Moleküle, die sich in der Regel durch ihre Hydrophobie or Amphiphilie auszeichnen. Beispiele für Lipide sind unter anderem Fette, Fettsäuren, Wachse, Triglyceride, Steroide und Phospholipide. Lipide sind Hauptbestandteil der biologischen Membranen aller Zellen. Daher wirken einige bakterielle Lipidstrukturen und Glykolipide als Pathogen assoziiertes molekulares Muster (PAMPs) und werden durch das Immunsystem erkannt. Diverse Lipide und Lipidkomplexe werden daher als Immunstimulans verwendet.

Lipide sind kleine organische Moleküle, die sich in der Regel durch ihre Hydrophobie or Amphiphilie auszeichnen. Beispiele für Lipide sind unter anderem Fette, Fettsäuren, Wachse, Triglyceride,... mehr erfahren »
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Lipide

Lipide sind kleine organische Moleküle, die sich in der Regel durch ihre Hydrophobie or Amphiphilie auszeichnen. Beispiele für Lipide sind unter anderem Fette, Fettsäuren, Wachse, Triglyceride, Steroide und Phospholipide. Lipide sind Hauptbestandteil der biologischen Membranen aller Zellen. Daher wirken einige bakterielle Lipidstrukturen und Glykolipide als Pathogen assoziiertes molekulares Muster (PAMPs) und werden durch das Immunsystem erkannt. Diverse Lipide und Lipidkomplexe werden daher als Immunstimulans verwendet.

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(±)14(15)-DiHETE MaxSpec(R) Standard
(±)14(15)-DiHETE MaxSpec(R) Standard

Artikelnummer: Cay29140-10

(±)14(15)-DiHETE is an oxylipin and a metabolite of the omega-3 fatty acid eicosapentaenoic acid (EPA, Cay-90110, Cay-90110.1, Cay-21908). It is formed via cytochrome P450-mediated epoxidation of EPA to (±)14(15)-EpETE (Cay-10173), followed by conversion of the epoxide to a diol by soluble epoxide hydrolase....
Schlagworte: (±)14,15-dihydroxy-5Z,8Z,11Z,17Z-eicosatetraenoic acid, (±)14,15-dihydroxy-eicosa-5,8,11,17-Tetraenoic Acid
Anwendung: MS, Quantitative grade standard
CAS 119433-37-3
MW: 336.5 D
158,00 €
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14(S)-HDHA MaxSpec(R) Standard
14(S)-HDHA MaxSpec(R) Standard

Artikelnummer: Cay29142-10

14(S)-HDHA is an oxygenation product formed by 12-lipoxygenase (12-LO) or 15-LO processing of docosahexaenoic acid (DHA, Cay-90310). It is a precursor to the pro-resolving mediator maresin 1 (Cay-10878) and has been found in peritoneal exudates isolated from a mouse model of zymosan-induced peritonitis. 14(S)-HDHA...
Schlagworte: 14S-hydroxy-4Z,7Z,10Z,12E,16Z,19Z-docosahexaenoic acid, 14(S)-hydroxy Docosahexaenoic Acid, 14(S)-HDoHE
Anwendung: MS, Quantitative grade standard
CAS 119433-37-3
MW: 344.5 D
132,00 €
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(25S)-Delta7-Dafachronic Acid
(25S)-Delta7-Dafachronic Acid

Artikelnummer: Cay14101-100

During unfavorable environmental conditions, C. elegans larvae undergo arrest and form dauer larvae that can attach to other animals as a parasitic strategy for survival. DAF-12 is an orphan nuclear hormone receptor that regulates dauer larva diapause, reproductive development, fat metabolism, and life...
Schlagworte: UPF-1404, (5alpha,25S)-3-oxo-cholest-7-en-26-oic acid
Anwendung: DAF-12 inhibitor
CAS 949004-12-0
MW: 414.6 D
ab 332,00 €
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Prostaglandin A2
Prostaglandin A2

Artikelnummer: Cay10210-1

PGA2 is a naturally occurring prostaglandin in gorgonian corals where it may function in self defense. It is generally not present in mammals. PGA2 has low biological potency in most bioassays, but it does show some antiviral/antitumor activity. At a 25 µM concentration, PGA2 blocks the cell cycle progression of NIH...
Schlagworte: Medullin, PGA2, 9-oxo-15S-hydroxy-prosta-5Z,10,13E-trien-1-oic acid
Anwendung: Bioactive lipid assays
CAS 13345-50-1
MW: 334.5 D
ab 32,00 €
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Prostaglandin A1
Prostaglandin A1

Artikelnummer: Cay10010-50

Prostaglandin A1 (PGA1) was first isolated as a dehydration product of the PGE1 compounds found in human semen. It has been shown to cause renal vasodilation, increased urine sodium excretion, and lowered arterial pressure in hypertensive patients. It also has growth-inhibitory activity on tumor cells, the IC50...
Schlagworte: PGA1, 9-oxo-15S-hydroxy-prosta-10,13E-dien-1-oic acid
Anwendung: Bioactive lipid assays
CAS 14152-28-4
MW: 336.5 D
ab 35,00 €
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6-keto Prostaglandin F1alpha-d4
6-keto Prostaglandin F1alpha-d4

Artikelnummer: Cay315210-25

6-keto Prostaglandin F1alpha-d4 (6-keto PGF1alpha-d4) contains four deuterium atoms at the 3, 3', 4, and 4' positions. It is intended for use as an internal standard for the quantification of 6-keto PGF1alpha (Cay-15210) by GC- or LC-MS. 6-keto PGF1alpha is the inactive, non-enzymatic hydrolysis product of PGI2....
Schlagworte: 6-keto PGF1alpha-d4, 6-oxo-9alpha,11alpha,15S-trihydroxy-prost-13E-en-1-oic-3,3,4,4-d4 acid
Anwendung: Standard
CAS 82414-64-0
MW: 374.5 D
ab 65,00 €
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2-Arachidonoyl Glycerol-d5
2-Arachidonoyl Glycerol-d5

Artikelnummer: Cay362162-100

2-Arachidonoyl glycerol-d5 (2-AG-d5) contains five deuterium atoms at the 1, 1, 2, 3, and 3 positions of the glycerol moiety. It is intended for use as an internal standard for the quantification of 2-AG by GC- or LC-mass spectrometry. 2-Arachidonoyl glycerol (2-AG) is an endogenous agonist of the CB1 receptor....
Schlagworte: 2-AG-d5, 5Z,8Z,11Z,14Z-eicosatetraenoic acid, 2-glycerol-1,1,2,3,3-d5 ester
Anwendung: Standard
MW: 383.6 D
ab 65,00 €
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FTY720 Phosphate
FTY720 Phosphate

Artikelnummer: Cay10008639-1

FTY720 is a derivative of ISP-1 (myriocin), a fungal metabolite of the Chinese herb Iscaria sinclarii as well as a structural analog of sphingosine. It is a novel immune modulator that prolongs allograft transplant survival in numerous models by inhibiting lymphocyte emigration from lymphoid organs. In vivo, FTY720...
Schlagworte: FTY720P, 2-amino-2[2-(4-octylphenyl)ethyl]-1,3-propanediol, mono dihydrogen phosphate ester
Anwendung: Sphingosine analog
CAS 402615-91-2
MW: 387.5 D
ab 110,00 €
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1-Oleoyl Lysophosphatidic Acid
1-Oleoyl Lysophosphatidic Acid

Artikelnummer: Cay10010093-5

1-Oleoyl lysophosphatidic acid is a species of lysophosphatidic acid (LPA) containing oleic acid at the sn-1 position. Phosphatidic acid is produced either directly through the action of phospholipase D (PLD) or through a two step process involving liberation of diacylglycerol (DAG) by phospholipase C (PLC) followed...
Schlagworte: 1-Oleoyl LPA, Oleoyl-sn-3-Glycerophosphate, 1-O-9Z-octadecenoyl-sn-glyceryl-3-phosphoric acid
Anwendung: Bioactive lipid assays
CAS 65528-98-5
MW: 436.5 D
ab 19,00 €
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Prostaglandin J2
Prostaglandin J2

Artikelnummer: Cay18500-500

Prostaglandin J2 (PGJ2) is formed from PGD2 by the elimination of the C-9 hydroxyl group, a process which is accelerated by the presence of albumin. PGJ2 inhibits platelet aggregation with an IC50 of about 5-10 nM. PGJ2 has antimitotic and antiproliferative effects on a variety of cultured normal cells and tumor...
Schlagworte: PGJ2, 11-oxo-15S-hydroxy-prosta-5Z,9,13E-trien-1-oic acid
Anwendung: Bioactive lipid assays
CAS 60203-57-8
MW: 334.5 D
ab 82,00 €
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Plant Sterol Mixture, (qualitative)
Plant Sterol Mixture, (qualitative)

Artikelnummer: MTY-1119

Source: natural, plant. Solvent: chloroform. Analytical Method: TLC, GC. Solubility: Chloroform. Concentration: 25 mg/ml
Schlagworte: Plant Sterol Mixture, (qualitative)
Anwendung: Sterols - Plant Sterols and Steryl Glucosides
176,00 €
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Serotonin (hydrochloride)
Serotonin (hydrochloride)

Artikelnummer: Cay14332-50

Serotonin is a monoamine neurotransmitter that is biochemically derived from tryptophan and produced in serotonergic neurons in the central nervous system and in enterochromaffin cells in the gastrointestinal tract. Serotonin is important in the regulation of mood, sleep, vomiting, sexuality, and appetite. Low...
Schlagworte: 5-HT, 5-Hydroxytryptamine, 3-(2-aminoethyl)-1H-indol-5-ol, monohydrochloride
Anwendung: Monoamine neurotransmitter
CAS 153-98-0
MW: 212.7 D
ab 37,00 €
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