Lipide

Lipide sind kleine organische Moleküle, die sich in der Regel durch ihre Hydrophobie or Amphiphilie auszeichnen. Beispiele für Lipide sind unter anderem Fette, Fettsäuren, Wachse, Triglyceride, Steroide und Phospholipide. Lipide sind Hauptbestandteil der biologischen Membranen aller Zellen. Daher wirken einige bakterielle Lipidstrukturen und Glykolipide als Pathogen assoziiertes molekulares Muster (PAMPs) und werden durch das Immunsystem erkannt. Diverse Lipide und Lipidkomplexe werden daher als Immunstimulans verwendet.

Lipide sind kleine organische Moleküle, die sich in der Regel durch ihre Hydrophobie or Amphiphilie auszeichnen. Beispiele für Lipide sind unter anderem Fette, Fettsäuren, Wachse, Triglyceride,... mehr erfahren »
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Lipide

Lipide sind kleine organische Moleküle, die sich in der Regel durch ihre Hydrophobie or Amphiphilie auszeichnen. Beispiele für Lipide sind unter anderem Fette, Fettsäuren, Wachse, Triglyceride, Steroide und Phospholipide. Lipide sind Hauptbestandteil der biologischen Membranen aller Zellen. Daher wirken einige bakterielle Lipidstrukturen und Glykolipide als Pathogen assoziiertes molekulares Muster (PAMPs) und werden durch das Immunsystem erkannt. Diverse Lipide und Lipidkomplexe werden daher als Immunstimulans verwendet.

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Resolvin D1 MaxSpec(R) Standard
Resolvin D1 MaxSpec(R) Standard

Artikelnummer: Cay25905-10

Resolvins are a family of potent lipid mediators derived from both eicosapentaenoic acid (EPA, Cay-90110) and docosahexaenoic acid (DHA, Cay-90310). In addition to being anti-inflammatory, resolvins promote the resolution of the inflammatory response back to a non-inflamed state. Resolvin D1 (RvD1) is produced...
Schlagworte: 17(S)-Resolvin D1, RvD1, 7S,8R,17S-trihydroxy-4Z,9E,11E,13Z,15E,19Z-docosahexaenoic acid
Anwendung: Quantitative MS
CAS 872993-05-0
MW: 376.5 D
219,00 €
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Arachidic Acid-d2
Arachidic Acid-d2

Artikelnummer: Cay28083-5

Arachidic acid-d2 is intended for use as an internal standard for the quantification of arachidic acid (Cay-9000339, Cay-21906) by GC- or LC-MS. Arachidic acid is a long-chain saturated fatty acid that has been found in peanut butter and anaerobic fungi. It inhibits rabbit neutrophil aggregation induced by...
Schlagworte: Arachic Acid-d2, Eicosanoate-d2, Icosanoic Acid-d2, eicosanoic-2,2-d2 acid
Anwendung: GC-MS, LC-MS, Internal standard, Quantification, Saturated long-chain fatty acid
CAS 232600-70-3
MW: 314.5 D
ab 99,00 €
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Stearidonic Acid ethyl ester
Stearidonic Acid ethyl ester

Artikelnummer: Cay10006856-1

Stearidonic acid (18:4omega-3) is a rare polyunsaturated fatty acid of the omega-3 series. In normal humans, it represents less than 0.25% of serum phospholipid fatty acids. It is present in certain natural oils such as echium and black currant seed, and to the extent that these oils are incorporated into...
Schlagworte: Ethyl Stearidonate, Moroctic Acid ethyl ester, 6Z,9Z,12Z,15Z-octadecatetraenoic acid, ethyl ester
Anwendung: Bioactive lipid assays
CAS 119798-44-6
MW: 304.5 D
ab 57,00 €
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11-cis Vaccenyl Acetate
11-cis Vaccenyl Acetate

Artikelnummer: Cay10010101-10

The mating and social behaviors of insects are largely orchestrated by a suite of volatile hydrocarbon pheromones. 11-cis Vaccenyl acetate is the male-specific mating pheromone of the fruit fly D. melanogaster. It acts selectively through the Or67d odorant receptor to control mating behavior in both male and female...
Schlagworte: (11Z)-11-octadecen-1-ol, acetate
Anwendung: Mating pheromone
CAS 6186-98-7
MW: 310.5 D
ab 23,00 €
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Prostaglandin E2-d9
Prostaglandin E2-d9

Artikelnummer: Cay10581-250

PGE2-d9 contains nine deuterium atoms at the 17, 17', 18, 18', 19, 19', 20, 20, and 20' positions. It is intended for use as an internal standard for the quantification of PGE2 by GC- or LC-mass spectrometry (MS). PGE2 is one of the primary cyclooxygenase products of arachidonic acid and one of the most widely...
Schlagworte: Dinoprostone-d9, PGE2-d9, 9-oxo-11alpha,15S-dihydroxy-prosta-5Z,13E-dien-1-oic-17,17,18,18,19,19,20,20,20-d9 acid
Anwendung: Standard
CAS 1356347-42-6
MW: 361.5 D
ab 64,00 €
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Oleoyl Serinol
Oleoyl Serinol

Artikelnummer: Cay13637-100

Oleoyl serinol is an analog of ceramide and an agonist of the cannabinoid receptor GPR119 that has an EC50 value of 12 µM for stimulating secretion of GLP-1 in mouse endocrine GLUTag cells. It has been found in E. coli that express human microbiota N-acyl synthase (hmNAS) genes. It induces cell death of F-11 murine...
Schlagworte: N-Oleoyl Serinol, S-18, N-[2-hydroxy-1-(hydroxymethyl)ethyl]-9Z-octadecenamide
Anwendung: GPR119 agonist
CAS 72809-08-6
MW: 355.6 D
ab 42,00 €
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(±)14(15)-DiHETE
(±)14(15)-DiHETE

Artikelnummer: Cay10006998-100

Eicosapentaenoic acid (EPA, Cay-90110) is an omega-3 fatty acid abundantly available in marine organisms. (±)14(15)-DiHETE is one of the major metabolites produced when EPA is incubated with rat liver microsomes and a rat colitis homogenate. The route of production likely proceeds through cytochrome P450-catalyzed...
Schlagworte: (±)14,15-dihydroxy-eicosa-5,8,11,17-Tetraenoic Acid, (±)14,15-dihydroxy-5Z,8Z,11Z,17Z-eicosatetraenoic acid
Anwendung: Bioactive lipid assays
MW: 336.5 D
ab 105,00 €
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(±)17-HDHA MaxSpec(R) Standard
(±)17-HDHA MaxSpec(R) Standard

Artikelnummer: Cay10007223-100

(±)17-HDHA is an autoxidation product of docosahexaenoic acid (DHA, Cay-90310) in vitro. It is also produced from incubations of DHA in rat liver, brain, and intestinal microsomes. 17(S)-HDHA (Cay-10009799) could be produced by enzymatic oxidation of DHA using soybean lipoxygenase (LO) and is the putative product of...
Schlagworte: 17-hydroxy Docosahexaenoic Acid, 17-hydroxy DHA, (±)17-HDoHE
Anwendung: Quantitative MS
CAS 90780-52-2
MW: 354.5 D
272,00 €
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15(R)-17-phenyl trinor Prostaglandin F2alpha ethyl amide
15(R)-17-phenyl trinor Prostaglandin F2alpha ethyl amide

Artikelnummer: Cay10008127-10

15(R)-17-phenyl trinor Prostaglandin F2alpha ethyl amide (15(R)-17-phenyl trinor PGF2alpha ethyl amide) is an isomer of bimatoprost, characterized by an inverted (beta) hydroxyl group at C-15. While this isomer has not been characterized, the comparable inversion of 15-hydroxyl groups, from (S) to (R), on other...
Schlagworte: 15(R)-17-phenyl trinor PGF2alpha ethyl amide, 15(R)-Bimatoprost,...
Anwendung: Bioactive lipid assays
CAS 1163135-92-9
MW: 415.6 D
ab 80,00 €
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16(17)-DiHDPA
16(17)-DiHDPA

Artikelnummer: Cay18176-100

(±)16(17)-DiHDPA is produced from cytochrome P450 epoxygenase action on docosahexaenoic acid (DHA, Cay-90310). It has been shown to inhibit VEGF-induced angiogenesis and reduce cancer cell metastasis in mice.
Schlagworte: 16,17-dihydroxy-4Z,7Z,10Z,13Z,19Z-docosapentaenoic acid
Anwendung: Angiogenesis inhibitor
CAS 1345275-27-5
MW: 362.5 D
ab 87,00 €
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Tauro-beta-muricholic Acid (sodium salt)
Tauro-beta-muricholic Acid (sodium salt)

Artikelnummer: Cay20289-500

Tauro-beta-muricholic acid (TbetaMCA) is a competitive and reversible antagonist of the farnesoid X receptor (FXR, IC50 = 40 µM) and a taurine-conjugated form of the murine-specific primary bile acid beta-muricholic acid (Cay-20287). TbetaMCA accumulates in germ-free mice under normal conditions but is reduced after...
Schlagworte: Tauro-beta-muricholate, TbetaMCA, 2-[[(3alpha,5beta,6beta,7beta)-3,6,7-trihydroxy-24-oxocholan-24-yl]amino]-ethanesulfonic...
Anwendung: FXR antagonist
CAS 145022-92-0
MW: 537.7 D
ab 73,00 €
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Leukotriene E4
Leukotriene E4

Artikelnummer: Cay20410-50

Leukotriene E4 (LTE4) is produced by the action of dipeptidase on LTD4, leaving only the cysteinyl group still attached to the fatty acid backbone. It is one of the constituents of slow-reacting substance of anaphylaxis (SRS-A). LTE4 is considerably less active (8 to 12-fold) than LTC4 in the biological activities...
Schlagworte: LTE4, 5S-hydroxy-6R-(S-cysteinyl)-7E,9E,11Z,14Z-eicosatetraenoic acid
Anwendung: Bioactive lipid assays
CAS 75715-89-8
MW: 439.6 D
ab 90,00 €
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