Lipide

Lipide sind kleine organische Moleküle, die sich in der Regel durch ihre Hydrophobie or Amphiphilie auszeichnen. Beispiele für Lipide sind unter anderem Fette, Fettsäuren, Wachse, Triglyceride, Steroide und Phospholipide. Lipide sind Hauptbestandteil der biologischen Membranen aller Zellen. Daher wirken einige bakterielle Lipidstrukturen und Glykolipide als Pathogen assoziiertes molekulares Muster (PAMPs) und werden durch das Immunsystem erkannt. Diverse Lipide und Lipidkomplexe werden daher als Immunstimulans verwendet.

Lipide sind kleine organische Moleküle, die sich in der Regel durch ihre Hydrophobie or Amphiphilie auszeichnen. Beispiele für Lipide sind unter anderem Fette, Fettsäuren, Wachse, Triglyceride,... mehr erfahren »
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Lipide

Lipide sind kleine organische Moleküle, die sich in der Regel durch ihre Hydrophobie or Amphiphilie auszeichnen. Beispiele für Lipide sind unter anderem Fette, Fettsäuren, Wachse, Triglyceride, Steroide und Phospholipide. Lipide sind Hauptbestandteil der biologischen Membranen aller Zellen. Daher wirken einige bakterielle Lipidstrukturen und Glykolipide als Pathogen assoziiertes molekulares Muster (PAMPs) und werden durch das Immunsystem erkannt. Diverse Lipide und Lipidkomplexe werden daher als Immunstimulans verwendet.

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Arachidic Acid
Arachidic Acid

Artikelnummer: Cay9000339-100

Arachidic acid is a long-chain saturated fatty acid that has been found in peanut butter and anaerobic fungi. It inhibits rabbit neutrophil aggregation induced by N-formyl-methionyl-leucyl-phenylalanine (fMLP, Cay-21495) when used at a concentration of 5 µM. Formulations containing arachidic acid have been used as...
Schlagworte: n-Eicosanoic Acid, Arachic Acid, C20:0, Icosanoic Acid, NSC 93983, eicosanoic acid
Anwendung: Bioactive lipid assays
CAS 506-30-9
MW: 312.5 D
ab 13,00 €
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Prostaglandin E2-d9
Prostaglandin E2-d9

Artikelnummer: Cay10581-250

PGE2-d9 contains nine deuterium atoms at the 17, 17', 18, 18', 19, 19', 20, 20, and 20' positions. It is intended for use as an internal standard for the quantification of PGE2 by GC- or LC-mass spectrometry (MS). PGE2 is one of the primary cyclooxygenase products of arachidonic acid and one of the most widely...
Schlagworte: Dinoprostone-d9, PGE2-d9, 9-oxo-11alpha,15S-dihydroxy-prosta-5Z,13E-dien-1-oic-17,17,18,18,19,19,20,20,20-d9 acid
Anwendung: Standard
CAS 1356347-42-6
MW: 361.5 D
ab 64,00 €
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N-pentadecanoyl-L-Homoserine lactone
N-pentadecanoyl-L-Homoserine lactone

Artikelnummer: Cay13094-5

Quorum sensing is a regulatory system used by bacteria for controlling gene expression in response to increasing cell density. This regulatory process manifests itself with a variety of phenotypes including biofilm formation and virulence factor production. Coordinated gene expression is achieved by the production,...
Schlagworte: C15-HSL, N-[(3S)-tetrahydro-2-oxo-3-furanyl]-pentadecanamide
Anwendung: Antibiotic
CAS 182359-66-6
MW: 325.5 D
ab 38,00 €
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N-octadecanoyl-L-Homoserine lactone
N-octadecanoyl-L-Homoserine lactone

Artikelnummer: Cay13209-5

Quorum sensing is a regulatory system used by bacteria for controlling gene expression in response to increasing cell density. This regulatory process manifests itself with a variety of phenotypes including biofilm formation and virulence factor production. Coordinated gene expression is achieved by the production,...
Schlagworte: C18-HSL, N-[(3S)-tetrahydro-2-oxo-3-furanyl]-octadecanamide
Anwendung: Bioactive lipid assays
CAS 479050-96-9
MW: 367.6 D
ab 38,00 €
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Oleoyl Serinol
Oleoyl Serinol

Artikelnummer: Cay13637-100

Oleoyl serinol is an analog of ceramide and an agonist of the cannabinoid receptor GPR119 that has an EC50 value of 12 µM for stimulating secretion of GLP-1 in mouse endocrine GLUTag cells. It has been found in E. coli that express human microbiota N-acyl synthase (hmNAS) genes. It induces cell death of F-11 murine...
Schlagworte: N-Oleoyl Serinol, S-18, N-[2-hydroxy-1-(hydroxymethyl)ethyl]-9Z-octadecenamide
Anwendung: GPR119 agonist
CAS 72809-08-6
MW: 355.6 D
ab 42,00 €
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N-undecanoyl-L-Homoserine lactone
N-undecanoyl-L-Homoserine lactone

Artikelnummer: Cay16827-5

Quorum sensing is a regulatory system used by bacteria for controlling gene expression in response to increasing cell density. This regulatory process manifests itself with a variety of phenotypes including biofilm formation and virulence factor production. Coordinated gene expression is achieved by the production,...
Schlagworte: C11-HSL, N-[(3S)-tetrahydro-2-oxo-3-furanyl]-undecanamide
Anwendung: Bioactive lipid assays
CAS 216596-71-3
MW: 269.4 D
ab 38,00 €
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15-deoxy-Delta12,14-Prostaglandin J2
15-deoxy-Delta12,14-Prostaglandin J2

Artikelnummer: Cay18570-1

15-deoxy-Delta12,14-Prostaglandin J2 (15-deoxy-Delta12,14-PGJ2) is formed from PGD2 by the elimination of two molecules of water. It binds selectively to PPARgamma with an EC50 value of 2 µM in a murine chimera system. 15-deoxy-Delta12,14-PGJ2 is more potent than PGD2, Delta12-PGJ2, and PGJ2 in stimulating...
Schlagworte: 15-deoxy-Delta12,14-PGJ2, 11-oxo-prosta-5Z,9,12E,14E-tetraen-1-oic acid
Anwendung: Bioactive lipid assays
CAS 87893-55-8
MW: 316,4 D
ab 32,00 €
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Rutaecarpine
Rutaecarpine

Artikelnummer: Cay22897-25

Rutaecarpine is a quinazolinone alkaloid originally isolated from E. rutaecarpa that has diverse biological activities. It inhibits COX-1 and COX-2 in BMMC cells (IC50s = 8.7 and 0.28 µM, respectively) and is selective for COX-2 in HEK293 cells (IC50s = >400 and 2.8 µM, for COX-1 and COX-2, respectively). It slows...
Schlagworte: NSC 258317, 8,13-dihydro-indolo[2',3':3,4]pyrido[2,1-b]quinazolin-5(7H)-one
Anwendung: COX-2 inhibitor
CAS 84-26-4
MW: 287.3 D
ab 49,00 €
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15(R)-17-phenyl trinor Prostaglandin F2alpha ethyl amide
15(R)-17-phenyl trinor Prostaglandin F2alpha ethyl amide

Artikelnummer: Cay10008127-10

15(R)-17-phenyl trinor Prostaglandin F2alpha ethyl amide (15(R)-17-phenyl trinor PGF2alpha ethyl amide) is an isomer of bimatoprost, characterized by an inverted (beta) hydroxyl group at C-15. While this isomer has not been characterized, the comparable inversion of 15-hydroxyl groups, from (S) to (R), on other...
Schlagworte: 15(R)-17-phenyl trinor PGF2alpha ethyl amide, 15(R)-Bimatoprost,...
Anwendung: Bioactive lipid assays
CAS 1163135-92-9
MW: 415.6 D
ab 80,00 €
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25(R)-27-hydroxy Cholesterol
25(R)-27-hydroxy Cholesterol

Artikelnummer: Cay14790-1

The liver X receptors (LXRalpha and LXRbeta) are nuclear hormone receptors whose native ligands, oxysterols, induce the expression of genes involved in cholesterol and fatty acid metabolism. 27-hydroxy Cholesterol, a sterol 27-hydroxylase-mediated cholesterol hydroxylation product, activates LXRalpha and LXRbeta in...
Schlagworte: (25R)-26-hydroxy cholesterol, (25R)-cholest-5-ene-3beta,26-diol
Anwendung: LXR alpha / beta activator
CAS 20380-11-4
MW: 402.7 D
ab 57,00 €
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Leukotriene E4
Leukotriene E4

Artikelnummer: Cay20410-50

Leukotriene E4 (LTE4) is produced by the action of dipeptidase on LTD4, leaving only the cysteinyl group still attached to the fatty acid backbone. It is one of the constituents of slow-reacting substance of anaphylaxis (SRS-A). LTE4 is considerably less active (8 to 12-fold) than LTC4 in the biological activities...
Schlagworte: LTE4, 5S-hydroxy-6R-(S-cysteinyl)-7E,9E,11Z,14Z-eicosatetraenoic acid
Anwendung: Bioactive lipid assays
CAS 75715-89-8
MW: 439.6 D
ab 90,00 €
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1-Oleoyl Lysophosphatidic Acid (sodium salt)
1-Oleoyl Lysophosphatidic Acid (sodium salt)

Artikelnummer: Cay62215-10

1-Oleoyl lysophosphatidic acid is a species of lysophosphatidic acid (LPA) containing oleic acid at the sn-1 position. Phosphatidic acid is produced either directly through the action of PLD or through a two step process involving liberation of DAG by PLC followed by phosphorylation of DAG by diglycerol kinase....
Schlagworte: Oleoyl-sn-3-glycerophosphate, 1-O-9Z-octadecenoyl-sn-glyceryl-3-phosphoric acid, sodium salt
Anwendung: Bioactive lipid assays
CAS 22556-62-3
MW: 458.5 D
ab 19,00 €
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