Lipide

Lipide sind kleine organische Moleküle, die sich in der Regel durch ihre Hydrophobie or Amphiphilie auszeichnen. Beispiele für Lipide sind unter anderem Fette, Fettsäuren, Wachse, Triglyceride, Steroide und Phospholipide. Lipide sind Hauptbestandteil der biologischen Membranen aller Zellen. Daher wirken einige bakterielle Lipidstrukturen und Glykolipide als Pathogen assoziiertes molekulares Muster (PAMPs) und werden durch das Immunsystem erkannt. Diverse Lipide und Lipidkomplexe werden daher als Immunstimulans verwendet.

Lipide sind kleine organische Moleküle, die sich in der Regel durch ihre Hydrophobie or Amphiphilie auszeichnen. Beispiele für Lipide sind unter anderem Fette, Fettsäuren, Wachse, Triglyceride,... mehr erfahren »
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Lipide

Lipide sind kleine organische Moleküle, die sich in der Regel durch ihre Hydrophobie or Amphiphilie auszeichnen. Beispiele für Lipide sind unter anderem Fette, Fettsäuren, Wachse, Triglyceride, Steroide und Phospholipide. Lipide sind Hauptbestandteil der biologischen Membranen aller Zellen. Daher wirken einige bakterielle Lipidstrukturen und Glykolipide als Pathogen assoziiertes molekulares Muster (PAMPs) und werden durch das Immunsystem erkannt. Diverse Lipide und Lipidkomplexe werden daher als Immunstimulans verwendet.

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Arachidonic Acid-d11
Arachidonic Acid-d11

Artikelnummer: Cay10006758-100

Arachidonic acid-d11 contains 11 deuterium atoms at the 16, 16, 17, 17, 18, 18, 19, 19, 20, 20, and 20 positions. It is intended for use as an internal standard for the quantification of arachidonic acid (Cay-90010) by GC- or LC-mass spectrometry. Arachidonic acid is an essential fatty acid and a precursor for all...
Schlagworte: AA-d11, 5Z,8Z,11Z,14Z-eicosatetraenoic-16,16,17,17,18,18,19,19,20,20,20-d11 acid
Anwendung: GC-MS, LC-MS, Internal standard
MW: 315.5 D
ab 48,00 €
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Prostaglandin E2-d9
Prostaglandin E2-d9

Artikelnummer: Cay10581-50

PGE2-d9 contains nine deuterium atoms at the 17, 17', 18, 18', 19, 19', 20, 20, and 20' positions. It is intended for use as an internal standard for the quantification of PGE2 by GC- or LC-mass spectrometry (MS). PGE2 is one of the primary cyclooxygenase products of arachidonic acid and one of the most widely...
Schlagworte: Dinoprostone-d9, PGE2-d9, 9-oxo-11alpha,15S-dihydroxy-prosta-5Z,13E-dien-1-oic-17,17,18,18,19,19,20,20,20-d9 acid
Anwendung: Standard
CAS 1356347-42-6
MW: 361.5 D
ab 64,00 €
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Prostaglandin D2-d4
Prostaglandin D2-d4

Artikelnummer: Cay312010-25

Prostaglandin D2-d4 (PGD2-d4) contains four deuterium atoms at the 3, 3', 4, and 4' positions. It is intended for use as an internal standard for the quantification of PGD2 by GC- or LC-mass spectrometry. PGD2 is the major eicosanoid product of mast cells and is released in large quantities during allergic and...
Schlagworte: PGD2-d4, 9alpha,15S-dihydroxy-11-oxo-prosta-5Z,13E-dien-1-oic-3,3,4,4-d4 acid
Anwendung: Standard
CAS 211105-29-2
MW: 356.5 D
ab 94,00 €
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Prostaglandin F2alpha-d4
Prostaglandin F2alpha-d4

Artikelnummer: Cay316010-25

Prostaglandin F2alpha-d4 (PGF2alpha-d4) contains four deuterium atoms at the 3, 3', 4, and 4' positions. It is intended for use as an internal standard for the quantification of PGF2alpha (Cay-16010) by GC- or LC-mass spectrometry. PGF2alpha is a widely distributed prostaglandin occurring in many species. It causes...
Schlagworte: Dinoprost-d4, PGF2alpha-d4, 9alpha,11alpha,15S-trihydroxy-prosta-5Z,13E-dien-1-oic-3,3,4,4-d4 acid
Anwendung: Standard
CAS 34210-11-2
MW: 358.5 D
ab 44,00 €
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13,14-dihydro-15-keto Prostaglandin E2
13,14-dihydro-15-keto Prostaglandin E2

Artikelnummer: Cay14650-1

13,14-dihydro-15-keto Prostaglandin E2 (13,14-dihydro-15-keto PGE2) is the primary metabolite of PGE2 (Cay-14010) in plasma. Endogenous or infused PGE2 is rapidly metabolized by the enzymes 15-hydroxy PGDH and 15-oxo-PG Delta13-reductase to form 13,14-dihydro-15-keto PGE2. 13,14-dihydro-15-keto PGE2 accumulates to...
Schlagworte: 13,14-dihydro-15-keto PGE2, 9,15-dioxo-11alpha-hydroxy-prost-5Z-en-1-oic acid
Anwendung: Bioactive lipid assays
CAS 363-23-5
MW: 352.5 D
ab 78,00 €
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6-keto Prostaglandin F1alpha
6-keto Prostaglandin F1alpha

Artikelnummer: Cay15210-1

6-keto prostaglandin F1alpha (6-keto PGF1alpha) is the inactive, non-enzymatic hydrolysis product of PGI2. 6-keto PGF1alpha serves as a useful marker of PGI2 biosynthesis in vivo. When [3H]-PGI2 is injected into healthy human males, 6.6% of the radioactivity is recovered from urine as [3H]-6-keto PGF1alpha.
Schlagworte: 6-keto PGF1alpha, 6-oxo-9alpha,11alpha,15S-trihydroxy-prost-13E-en-1-oic acid
Anwendung: Bioactive lipid assays
CAS 58962-34-8
MW: 370.5 D
ab 99,00 €
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Thromboxane B2
Thromboxane B2

Artikelnummer: Cay19030-1

TXB2 is a stable, biologically inert metabolite formed from the non-enzymatic hydrolysis of TXA2, which has a half-life of about 30 seconds. Urinary analysis of TXB2 accurately reflects intrarenal TXA2 synthesis, while measurement of 11-dehydro and 2,3-dinor thromboxane metabolites gives the best estimate of...
Schlagworte: TXB2, 9alpha,11,15S-trihydroxythromba-5Z,13E-dien-1-oic acid
Anwendung: Bioactive lipid assays
CAS 54397-85-2
MW: 370.5 D
ab 73,00 €
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Sphingosine-1-phosphate
Sphingosine-1-phosphate

Artikelnummer: Cay62570-1

Sphingosine-1-phosphate (S1P) is the product of phosphorylation of sphingosine by sphingosine kinase. Like many products of sphingomyelin, it exhibits a wide range of biological activities. Not only does it enhance cell growth, but it can inhibit the normal apoptotic response to a variety of stimuli. The ability of...
Schlagworte: S1P, Sphingosine-1-Phosphoric Acid, 2S-amino-4E-octadecene-1,3R-diol 1-(dihydrogen phosphate)
Anwendung: Bioactive lipid assays
CAS 26993-30-6
MW: 379.5 D
ab 119,00 €
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Prostaglandin A1
Prostaglandin A1

Artikelnummer: Cay10010-50

Prostaglandin A1 (PGA1) was first isolated as a dehydration product of the PGE1 compounds found in human semen. It has been shown to cause renal vasodilation, increased urine sodium excretion, and lowered arterial pressure in hypertensive patients. It also has growth-inhibitory activity on tumor cells, the IC50...
Schlagworte: PGA1, 9-oxo-15S-hydroxy-prosta-10,13E-dien-1-oic acid
Anwendung: Bioactive lipid assays
CAS 14152-28-4
MW: 336.5 D
ab 35,00 €
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Prostaglandin D2
Prostaglandin D2

Artikelnummer: Cay12010-1

Prostaglandin D2 (PGD2) is the major eicosanoid product of mast cells and is released in large quantities during allergic and asthmatic anaphylaxis. Mastocytosis patients produce excessive amounts of PGD2, which causes vasodilation, flushing, hypotension, and syncopal episodes. PGD2 is also produced in the brain via...
Schlagworte: PGD2, 9alpha,15S-dihydroxy-11-oxo-prosta-5Z,13E-dien-1-oic acid
Anwendung: Bioactive lipid assays
CAS 41598-07-6
MW: 352.5 D
ab 49,00 €
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Prostaglandin E2
Prostaglandin E2

Artikelnummer: Cay14010-1

PGE2 is one of the primary COX products of arachidonic acid (Cay-90010) and one of the most widely investigated prostaglandins. Its activity influences inflammation, fertility and parturition, gastric mucosal integrity, and immune modulation. The effects of PGE2 are transduced by at least four distinct receptors...
Schlagworte: Dinoprostone, PGE2, 9-oxo-11alpha,15S-dihydroxy-prosta-5Z,13E-dien-1-oic acid
Anwendung: Bioactive lipid assays
CAS 363-24-6
MW: 352.5 D
ab 25,00 €
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Thromboxane B2-d4
Thromboxane B2-d4

Artikelnummer: Cay319030-25

Thromboxane B2-d4 (TXB2-d4) contains four deuterium atoms at the 3, 3', 4, and 4' positions. It is intended for use as an internal standard for the quantification of TXB2 by GC- or LC-mass spectrometry. TXB2 is a stable, biologically inert metabolite formed from the non-enzymatic hydrolysis of TXA2, which has a...
Schlagworte: TXB2-d4, 9alpha,11,15S-trihydroxy-thromba-5Z,13E-dien-1-oic-3,3,4,4-d4 acid
Anwendung: Standard
CAS 1346112-79-5
MW: 374.5 D
ab 169,00 €
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