Lipide

Lipide sind kleine organische Moleküle, die sich in der Regel durch ihre Hydrophobie or Amphiphilie auszeichnen. Beispiele für Lipide sind unter anderem Fette, Fettsäuren, Wachse, Triglyceride, Steroide und Phospholipide. Lipide sind Hauptbestandteil der biologischen Membranen aller Zellen. Daher wirken einige bakterielle Lipidstrukturen und Glykolipide als Pathogen assoziiertes molekulares Muster (PAMPs) und werden durch das Immunsystem erkannt. Diverse Lipide und Lipidkomplexe werden daher als Immunstimulans verwendet.

Lipide sind kleine organische Moleküle, die sich in der Regel durch ihre Hydrophobie or Amphiphilie auszeichnen. Beispiele für Lipide sind unter anderem Fette, Fettsäuren, Wachse, Triglyceride,... mehr erfahren »
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Lipide

Lipide sind kleine organische Moleküle, die sich in der Regel durch ihre Hydrophobie or Amphiphilie auszeichnen. Beispiele für Lipide sind unter anderem Fette, Fettsäuren, Wachse, Triglyceride, Steroide und Phospholipide. Lipide sind Hauptbestandteil der biologischen Membranen aller Zellen. Daher wirken einige bakterielle Lipidstrukturen und Glykolipide als Pathogen assoziiertes molekulares Muster (PAMPs) und werden durch das Immunsystem erkannt. Diverse Lipide und Lipidkomplexe werden daher als Immunstimulans verwendet.

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(±)14(15)-DiHETE MaxSpec(R) Standard
(±)14(15)-DiHETE MaxSpec(R) Standard

Artikelnummer: Cay29140-10

(±)14(15)-DiHETE is an oxylipin and a metabolite of the omega-3 fatty acid eicosapentaenoic acid (EPA, Cay-90110, Cay-90110.1, Cay-21908). It is formed via cytochrome P450-mediated epoxidation of EPA to (±)14(15)-EpETE (Cay-10173), followed by conversion of the epoxide to a diol by soluble epoxide hydrolase....
Schlagworte: (±)14,15-dihydroxy-5Z,8Z,11Z,17Z-eicosatetraenoic acid, (±)14,15-dihydroxy-eicosa-5,8,11,17-Tetraenoic Acid
Anwendung: MS, Quantitative grade standard
CAS 119433-37-3
MW: 336.5 D
158,00 €
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14(S)-HDHA MaxSpec(R) Standard
14(S)-HDHA MaxSpec(R) Standard

Artikelnummer: Cay29142-10

14(S)-HDHA is an oxygenation product formed by 12-lipoxygenase (12-LO) or 15-LO processing of docosahexaenoic acid (DHA, Cay-90310). It is a precursor to the pro-resolving mediator maresin 1 (Cay-10878) and has been found in peritoneal exudates isolated from a mouse model of zymosan-induced peritonitis. 14(S)-HDHA...
Schlagworte: 14S-hydroxy-4Z,7Z,10Z,12E,16Z,19Z-docosahexaenoic acid, 14(S)-hydroxy Docosahexaenoic Acid, 14(S)-HDoHE
Anwendung: MS, Quantitative grade standard
CAS 119433-37-3
MW: 344.5 D
132,00 €
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(25S)-Delta7-Dafachronic Acid
(25S)-Delta7-Dafachronic Acid

Artikelnummer: Cay14101-100

During unfavorable environmental conditions, C. elegans larvae undergo arrest and form dauer larvae that can attach to other animals as a parasitic strategy for survival. DAF-12 is an orphan nuclear hormone receptor that regulates dauer larva diapause, reproductive development, fat metabolism, and life...
Schlagworte: UPF-1404, (5alpha,25S)-3-oxo-cholest-7-en-26-oic acid
Anwendung: DAF-12 inhibitor
CAS 949004-12-0
MW: 414.6 D
ab 332,00 €
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Plant Sterol Mixture, (qualitative)
Plant Sterol Mixture, (qualitative)

Artikelnummer: MTY-1119

Source: natural, plant. Solvent: chloroform. Analytical Method: TLC, GC. Solubility: Chloroform. Concentration: 25 mg/ml
Schlagworte: Plant Sterol Mixture, (qualitative)
Anwendung: Sterols - Plant Sterols and Steryl Glucosides
176,00 €
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5(S)-HETE
5(S)-HETE

Artikelnummer: Cay34230-25

5(S)-HETE is produced by the action of 5-LO on arachidonic acid to give 5(S)-HpETE, followed by reduction of the hydroperoxide. 5(S)-HETE has proliferative and chemotactic effects on granulocytes. When further metabolized to 5-oxoETE, it is a more potent eosinophil chemoattractant than leukotriene B4.
Schlagworte: 5S-hydroxy-6E,8Z,11Z,14Z-eicosatetraenoic acid
Anwendung: Bioactive lipid assays
CAS 70608-72-9
MW: 320.5 D
ab 115,00 €
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Xestospongin C
Xestospongin C

Artikelnummer: Cay64950-10

Xestospongin C is a marine natural product which was first isolated from Pacific basin sponges, and noted to have vasodilatory properties. Xestospongin C antagonizes the calcium-releasing action of inositol-1,4,5-trisphosphate (IP3) at the receptor level. Inositol phosphates are important signal transduction...
Schlagworte: Araguspongine E, XeC,...
Anwendung: Bioactive lipid assays
CAS 88903-69-9
MW: 446.7 D
ab 87,00 €
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Leukotriene B4
Leukotriene B4

Artikelnummer: Cay20110-25

Leukotriene B4 (LTB4) is a dihydroxy fatty acid derived from arachidonic acid through the 5-LO pathway. It promotes a number of leukocyte functions including aggregation, stimulation of ion fluxes, enhancement of lysosomal enzyme release, superoxide anion production, chemotaxis, and chemokinesis. In subnanomolar...
Schlagworte: LTB4, 5S,12R-dihydroxy-6Z,8E,10E,14Z-eicosatetraenoic acid
Anwendung: Bioactive lipid assays
CAS 71160-24-2
MW: 336.5 D
ab 148,00 €
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15(S)-HETE
15(S)-HETE

Artikelnummer: Cay34720-25

15(S)-HETE is a major arachidonic acid metabolite from the 15-lipoxygenase pathway. In mammals, 15(S)-HETE is synthesized in the respiratory epithelium, leukocytes, and reticulocytes. 15(S)-HETE is present in µg/ml concentrations in the nasal secretions of allergic rhinitis.
Schlagworte: 15S-hydroxy-5Z,8Z,11Z,13E-eicosatetraenoic acid
Anwendung: Bioactive lipid assays
CAS 54845-95-3
MW: 320.5 D
ab 39,00 €
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(±)-Jasmonic Acid
(±)-Jasmonic Acid

Artikelnummer: Cay88300-100

Jasmonic acid, derived from alpha-linolenic acid (Cay-90210), is a plant growth regulator involved in the signaling mechanisms for a variety of conditions including plant defense, wound healing, tuberization, fruit ripening, and senescence.
Schlagworte: 3-oxo-2R-(2Z)2-penten-1R-yl-cyclopentaneacetic acid
Anwendung: Plant growth regulator
CAS 77026-92-7
MW: 210.3 D
ab 19,00 €
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Prostaglandin A1
Prostaglandin A1

Artikelnummer: Cay10010-50

Prostaglandin A1 (PGA1) was first isolated as a dehydration product of the PGE1 compounds found in human semen. It has been shown to cause renal vasodilation, increased urine sodium excretion, and lowered arterial pressure in hypertensive patients. It also has growth-inhibitory activity on tumor cells, the IC50...
Schlagworte: PGA1, 9-oxo-15S-hydroxy-prosta-10,13E-dien-1-oic acid
Anwendung: Bioactive lipid assays
CAS 14152-28-4
MW: 336.5 D
ab 35,00 €
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6-trans-12-epi Leukotriene B4
6-trans-12-epi Leukotriene B4

Artikelnummer: Cay35265-25

6-trans-12-epi Leukotriene B4 (LTB4) is a non-enzymatic hydrolysis product of LTA4. It was originally isolated from glycogen-induced rabbit peritoneal polymorphonuclear leukocytes (PMNL). 6-trans-12-epi LTB4 is weakly chemotactic for PMNL, with approximately 20 times less potency than LTB4, and has no effect on the...
Schlagworte: 6-trans-12-epi LTB4, 5S,12S-dihydroxy-6E,8E,10E,14Z-eicosatetraenoic acid
Anwendung: Bioactive lipid assays
CAS 71548-19-1
MW: 336.5 D
ab 113,00 €
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2-Arachidonoyl Glycerol-d5
2-Arachidonoyl Glycerol-d5

Artikelnummer: Cay362162-100

2-Arachidonoyl glycerol-d5 (2-AG-d5) contains five deuterium atoms at the 1, 1, 2, 3, and 3 positions of the glycerol moiety. It is intended for use as an internal standard for the quantification of 2-AG by GC- or LC-mass spectrometry. 2-Arachidonoyl glycerol (2-AG) is an endogenous agonist of the CB1 receptor....
Schlagworte: 2-AG-d5, 5Z,8Z,11Z,14Z-eicosatetraenoic acid, 2-glycerol-1,1,2,3,3-d5 ester
Anwendung: Standard
MW: 383.6 D
ab 65,00 €
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