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Ionomycin (calcium salt) Artikelnummer: Cay11932-1
Ionomycin is a selective calcium ionophore derived from S. conglobatus that mobilizes intracellular calcium stores. It is used as a research tool to raise the intracellular level of calcium, to study calcium transport across biological membranes, and to stimulate the intracellular production of cytokines. This...
| Schlagworte: | 11,19R,21S-trihydroxy-4R,6S,8S,12R,14R,18R,20S-heptamethyl-22-[octahydro-5'S-[1R-hydroxyethyl]-2S,5'-dimethyl[2,2'R-bifura... |
| Anwendung: | Calcium ionophore |
| CAS | 56092-82-1 |
| MW: | 747.1 D |
ab 32,00 €
Arachidonic Acid-d11 Artikelnummer: Cay10006758-100
Arachidonic acid-d11 contains 11 deuterium atoms at the 16, 16, 17, 17, 18, 18, 19, 19, 20, 20, and 20 positions. It is intended for use as an internal standard for the quantification of arachidonic acid (Cay-90010) by GC- or LC-mass spectrometry. Arachidonic acid is an essential fatty acid and a precursor for all...
| Schlagworte: | AA-d11, 5Z,8Z,11Z,14Z-eicosatetraenoic-16,16,17,17,18,18,19,19,20,20,20-d11 acid |
| Anwendung: | GC-MS, LC-MS, Internal standard |
| MW: | 315.5 D |
ab 48,00 €
Latrunculin B Artikelnummer: AG-CN2-0031-M001
Isolated from Latrunculia magnifica. Cell permeable marine toxin. Disrupts microfilament-mediated processes. Actin polymerization inhibitor in vitro and in vivo by the formation of a 1:1 complex with monomeric G-actin. Less potent than Latrunculin A. May have fewer unwanted effects than latrunculin A and may be...
| Schlagworte: | LAT-B, NSC 339663 |
| Anwendung: | Actin polymerization inhibitor |
| CAS | 76343-94-7 |
| MW: | 395,5 D |
ab 99,00 €
(±)-EX-527 Artikelnummer: Cay10009798-5
EX-527 is an inhibitor of sirtuin 1 (SIRT1, IC50 = 0.098 µM). It is selective for SIRT1 over SIRT2, and SIRT3 (IC50s = 19.6 and 48.7 µM, respectively) and the cytochrome P450 (CYP) isoforms CYP3A4, CYP2D6, CYP2C9, CYP2C19, and CYP1A2 at 1 µM. EX-527 (50 µM) induces cell cycle arrest at the G1 phase in MCF-7 cells.
| Schlagworte: | 6-chloro-2,3,4,9-tetrahydro-1H-carbazole-1-carboxamide |
| Anwendung: | SIRT1 inhibitor |
| CAS | 49843-98-3 |
| MW: | 248.7 D |
ab 32,00 €
Bicine, ultra pure Artikelnummer: 01848.500
Bicine is an organic buffering agent. It is one of Good's buffers and has a pKa of 8.35 at 20°C. It is prepared by the reaction of glycine with ethylene oxide, followed by hydrolysis of the resultant lactone. Useful pH range: 7.8-8.8
| CAS | 150-25-4 |
| MW: | 163.17 |
ab 54,00 €
Resazurin (sodium salt) Artikelnummer: Cay14322-5
Resazurin is a blue non-fluorescent dye that when reduced to the highly red-fluorescent product resorufin (excitation: 530-540 nm, emission: 585-595 nm) can be used as a quantifiable detection agent for enzyme activity assays. The non-fluorescent resazurin can be used as an oxidation-reduction indicator in cell...
| Schlagworte: | 7-hydroxy-3H-phenoxazin-3-one-10-oxide, monosodium salt |
| Anwendung: | Enzyme activity assays, Cell viability assays |
| CAS | 62758-13-8 |
| MW: | 251.2 D |
ab 63,00 €
Imipenem (hydrate) Artikelnummer: Cay16039-100
Imipenem is an intravenous beta-lactam antibiotic effective against a wide range of Gram-positive and Gram-negative bacteria (MICs range from 0.5-2 µg/ml for E. cloacae and P. aeruginosa), including several multi-drug resistant bacterial species. Imipenem acts by interfering with bacterial cell wall synthesis.
| Schlagworte: | N-Formimidoyl Thienamycin,... |
| Anwendung: | Antibacterial antibiotic, Peptidoglycan biosynthesis inhibitor |
| CAS | 74431-23-5 |
| MW: | 317.4 D |
ab 57,00 €
BCIP, p-toluidine salt Artikelnummer: 02291.250
Soluble in DMF, hardly soluble in water. Use as alkaline phosphatase substrate forming a water insoluble blue reaction product. Often used together with NBT (Art.-Nr. 06428) for immunocytochemistry.
| Anwendung: | Substrate for alkaline phosphatase |
| CAS | 6578-06-9 |
| MW: | 433.60 |
ab 53,00 €
Sodium Dodecyl Sulfate (SDS), pure Artikelnummer: 04051.1
SDS is commonly used in the preparation of proteins for electrophoresis in SDS-PAGE. This compound works by disrupting non-covalent bonds in proteins, denaturing them and causing the proteins to lose their natural conformation. The new negative charge is significantly larger than the original charge of that protein....
| Anwendung: | Anionic detergent |
| CAS | 151-21-3 |
| MW: | 288.38 |
42,00 €
NADH, disodium salt Artikelnummer: 16132.1
Assay: >85% enzymatically
| Schlagworte: | beta-Nicotinamide-adenine-dinucleotide, reduced Na2-salt |
| CAS | 606-68-8 |
| MW: | 709.4 D |
ab 46,00 €
Urea, ultra pure Artikelnummer: 50250.1
Purity: >=99.5%. Suitable for electrophoresis
| Anwendung: | Denaturing agent |
| CAS | 57-13-6 |
| MW: | 60.06 |
39,00 €
Thiazolyl blue (MTT) 3-(4,5-Dimethyl-2-thiazolyl)-2... Artikelnummer: 15655.1
The water soluble MTT yields a yellowish solution. It is converted by mitochondrial dehydrogenases of metabolically active cells to an insoluble formazan product, which can be solubilized with DMSO. Read at 510 nm.
| Anwendung: | Cell viability assay |
| CAS | 298-93-1 |
| MW: | 414.33 |
ab 28,00 €
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