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Latrunculin B Artikelnummer: AG-CN2-0031-M001
Isolated from Latrunculia magnifica. Cell permeable marine toxin. Disrupts microfilament-mediated processes. Actin polymerization inhibitor in vitro and in vivo by the formation of a 1:1 complex with monomeric G-actin. Less potent than Latrunculin A. May have fewer unwanted effects than latrunculin A and may be...
| Schlagworte: | LAT-B, NSC 339663 |
| Anwendung: | Actin polymerization inhibitor |
| CAS | 76343-94-7 |
| MW: | 395,5 D |
ab 99,00 €
Gentamycin (Gentamicin) Sulfate Solution 50mg/ml... Artikelnummer: G2032.20
Broad spectrum, cell culture antibiotic that is non toxic to viruses and mammalian cells at antibacterial levels. Inhibits growth of gram positive and negative bacteria, and mycoplasma. Inhibits normal protein synthesis by binding to L6 protein of 50S ribosomal subunit. Useful antibiotic for Baculovirus expression...
| CAS | 1405-41-0 |
ab 98,00 €
(±)14(15)-DiHETE MaxSpec(R) Standard Artikelnummer: Cay29140-10
(±)14(15)-DiHETE is an oxylipin and a metabolite of the omega-3 fatty acid eicosapentaenoic acid (EPA, Cay-90110, Cay-90110.1, Cay-21908). It is formed via cytochrome P450-mediated epoxidation of EPA to (±)14(15)-EpETE (Cay-10173), followed by conversion of the epoxide to a diol by soluble epoxide hydrolase....
| Schlagworte: | (±)14,15-dihydroxy-5Z,8Z,11Z,17Z-eicosatetraenoic acid, (±)14,15-dihydroxy-eicosa-5,8,11,17-Tetraenoic Acid |
| Anwendung: | MS, Quantitative grade standard |
| CAS | 119433-37-3 |
| MW: | 336.5 D |
158,00 €
14(S)-HDHA MaxSpec(R) Standard Artikelnummer: Cay29142-10
14(S)-HDHA is an oxygenation product formed by 12-lipoxygenase (12-LO) or 15-LO processing of docosahexaenoic acid (DHA, Cay-90310). It is a precursor to the pro-resolving mediator maresin 1 (Cay-10878) and has been found in peritoneal exudates isolated from a mouse model of zymosan-induced peritonitis. 14(S)-HDHA...
| Schlagworte: | 14S-hydroxy-4Z,7Z,10Z,12E,16Z,19Z-docosahexaenoic acid, 14(S)-hydroxy Docosahexaenoic Acid, 14(S)-HDoHE |
| Anwendung: | MS, Quantitative grade standard |
| CAS | 119433-37-3 |
| MW: | 344.5 D |
132,00 €
(25S)-Delta7-Dafachronic Acid Artikelnummer: Cay14101-100
During unfavorable environmental conditions, C. elegans larvae undergo arrest and form dauer larvae that can attach to other animals as a parasitic strategy for survival. DAF-12 is an orphan nuclear hormone receptor that regulates dauer larva diapause, reproductive development, fat metabolism, and life...
| Schlagworte: | UPF-1404, (5alpha,25S)-3-oxo-cholest-7-en-26-oic acid |
| Anwendung: | DAF-12 inhibitor |
| CAS | 949004-12-0 |
| MW: | 414.6 D |
ab 332,00 €
MCC950 . Na Artikelnummer: AG-CR1-3615-M001
Crystalline solid. Soluble in water (10mg/ml), DMSO (10mg/ml), dimethyl formamide or ethanol (1mg/ml). Chemical. CAS: 256373-96-3. Formula: C20H23N2NaO5S. MW: 426.5. Synthetic. Potent, selective and orally available NLRP3 inflammasome inhibitor. Blocks the release of IL-1beta in macrophages primed with LPS and...
| Schlagworte: | MCC950, CP-456,773, CRID3, 1-(1,2,3,5,6,7-Hexahydro- s-indacen-4-yl)-3-[4-(1-hydroxy-1-methyl-ethyl)-furan-2-sulfonyl]urea |
| Anwendung: | NLRP3 inflammasome inhibitor |
| CAS | 256373-96-3 |
| MW: | 426,5 D |
ab 39,00 €
SIN-1 (chloride) Artikelnummer: Cay82220-50
As the active metabolite of molsidomine, SIN-1 (chloride) is a potent vasorelaxant and inhibitor of platelet aggregation. It produces both NO and superoxide and can therefore be used to generate peroxynitrite under physiological conditions.
| Schlagworte: | 3-Morpholino-sydnonimine, Linsidomine, 5-amino-3-(4-morpholinyl)-1,2,3-oxadiazolium chloride |
| Anwendung: | Peroxynitrite generation |
| CAS | 16142-27-1 |
| MW: | 206.6 D |
ab 18,00 €
COVID-19 Forschung
Remdesivir Artikelnummer: Cay30354-5
Remdesivir is a prodrug form of the antiviral nucleoside analog GS-441524 (Cay-30469). Upon entry into cells, remdesivir is metabolized into the nucleotide triphosphate GS-441524. Remdesivir is active against Middle East respiratory syndrome coronavirus (MERS-CoV) and severe acute respiratory syndrome CoV (SARS-CoV)...
| Schlagworte: | GS-5734, N-[(S)-hydroxyphenoxyphosphinyl)-L-alanine, 2-ethylbutyl ester, 6-ester with... |
| Anwendung: | GS-441524 prodrug, SARS type antiviral |
| CAS | 1809249-37-3 |
| MW: | 602.6 D |
ab 219,00 €
Bicine, ultra pure Artikelnummer: 01848.500
Bicine is an organic buffering agent. It is one of Good's buffers and has a pKa of 8.35 at 20°C. It is prepared by the reaction of glycine with ethylene oxide, followed by hydrolysis of the resultant lactone. Useful pH range: 7.8-8.8
| CAS | 150-25-4 |
| MW: | 163.17 |
ab 54,00 €
Imipenem (hydrate) Artikelnummer: Cay16039-100
Imipenem is an intravenous beta-lactam antibiotic effective against a wide range of Gram-positive and Gram-negative bacteria (MICs range from 0.5-2 µg/ml for E. cloacae and P. aeruginosa), including several multi-drug resistant bacterial species. Imipenem acts by interfering with bacterial cell wall synthesis.
| Schlagworte: | N-Formimidoyl Thienamycin,... |
| Anwendung: | Antibacterial antibiotic, Peptidoglycan biosynthesis inhibitor |
| CAS | 74431-23-5 |
| MW: | 317.4 D |
ab 57,00 €
Leupeptin (Ac-Leu-Leu-Arginal-hemisulfate) Artikelnummer: 12136.100
Purity: >96.5%, A reversible inhibitor of trypsin-like proteases and cysteine proteases. Soluble in water, ethanol, acetic acid and DMF. Stock solution: 10 mM in water, stable for 1 month at -20 °C. Effective conc.: 1-10 µM.
| Anwendung: | Inhibitor |
| CAS | 103476-89-7 |
| MW: | 475.6 |
ab 83,00 €
BCIP, p-toluidine salt Artikelnummer: 02291.250
Soluble in DMF, hardly soluble in water. Use as alkaline phosphatase substrate forming a water insoluble blue reaction product. Often used together with NBT (Art.-Nr. 06428) for immunocytochemistry.
| Anwendung: | Substrate for alkaline phosphatase |
| CAS | 6578-06-9 |
| MW: | 433.60 |
ab 53,00 €
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