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Anhydrotetracycline (hydrochloride) Artikelnummer: Cay10009542-50
The tetracycline repressor (TetR) is a transcriptional regulator which normally binds tightly to its palindromic tetO operator DNA, blocking gene expression. Tet causes the repressor to dissociate from the DNA, allowing transcription to occur. A novel reverse TetR (revTetR) requires tetracycline as a co-repressor to...
| Schlagworte: | 4-(dimethylamino)-1,4S,4aS,5,12,12aS-hexahydro-3,10,11,12a-tetrahydroxy-6-methyl-1,12-dioxo-2-naphthacenecarboxamide,... |
| Anwendung: | Antibiotic |
| CAS | 13803-65-1 |
| MW: | 462.9 D |
ab 45,00 €
Plant Sterol Mixture, (qualitative) Artikelnummer: MTY-1119
Source: natural, plant. Solvent: chloroform. Analytical Method: TLC, GC. Solubility: Chloroform. Concentration: 25 mg/ml
| Schlagworte: | Plant Sterol Mixture, (qualitative) |
| Anwendung: | Sterols - Plant Sterols and Steryl Glucosides |
176,00 €
Prostaglandin D1 Artikelnummer: Cay12000-1
Prostaglandin D1 (PGD1) is the 1-series analog of PGD2 (Cay-12010). It is an inhibitor of ADP-induced platelet aggregation in humans with an IC50 value of 320 ng/ml, about 1/10 as potent as PGD2.
| Schlagworte: | PGD1, 9alpha,15S-dihydroxy-11-oxo-prost-13E-en-1-oic acid |
| Anwendung: | Bioactive lipid assays |
| CAS | 17968-82-0 |
| MW: | 354.5 D |
ab 37,00 €
Cal-590(TM)-Dextran Conjugate *MW 10,000* Artikelnummer: ABD-20509
Calcium measurement is critical for numerous biological investigations. Fluorescent probes that show spectral responses upon binding calcium have enabled researchers to investigate changes in intracellular free calcium concentrations by using fluorescence microscopy, flow cytometry, fluorescence spectroscopy and...
| Anwendung: | IF, FC |
319,00 €
Vulpinic Acid Artikelnummer: Cay21685-100
Vulpinic acid is a lichen metabolite that has been found in L. vulpina and has diverse biological activities. It is active against C. perfringens, B. vulgatus, B. fragilis, B. loescheii, P. acnes, E. faecium, and methicillin-susceptible and -resistant S. aureus (MICs = 4-16 µg/ml). Vulpinic acid (25-800 µM) prevents...
| Schlagworte: | NSC 5897, alphaE-(3-hydroxy-5-oxo-4-phenyl-2(5H)-furanylidene)-benzeneacetic acid, methyl ester |
| Anwendung: | Bioactive lichen metabolite |
| CAS | 521-52-8 |
| MW: | 322.3 D |
ab 32,00 €
Thymohydroquinone Artikelnummer: Cay27558-10
Thymohydroquinone is a quinone that has been found in N. sativa seeds and has diverse biological activities. It scavenges 2,2-diphenyl-1-picrylhydrazyl (DPPH, Cay-14805) free radicals in a cell-free assay (IC50 = 2.4 µg/ml) and has a Trolox equivalent value of 2.6 in an oxygen radical absorbance capacity (ORAC)...
| Schlagworte: | NSC 34803, 2-methyl-5-(1-methylethyl)-1,4-benzenediol |
| Anwendung: | Bioactive quinone |
| CAS | 2217-60-9 |
| MW: | 166.2 D |
ab 32,00 €
Arachidic Acid-d2 Artikelnummer: Cay28083-5
Arachidic acid-d2 is intended for use as an internal standard for the quantification of arachidic acid (Cay-9000339, Cay-21906) by GC- or LC-MS. Arachidic acid is a long-chain saturated fatty acid that has been found in peanut butter and anaerobic fungi. It inhibits rabbit neutrophil aggregation induced by...
| Schlagworte: | Arachic Acid-d2, Eicosanoate-d2, Icosanoic Acid-d2, eicosanoic-2,2-d2 acid |
| Anwendung: | GC-MS, LC-MS, Internal standard, Quantification, Saturated long-chain fatty acid |
| CAS | 232600-70-3 |
| MW: | 314.5 D |
ab 99,00 €
NEU
(25S)-Delta7-Dafachronic Acid Artikelnummer: Cay14101-1
During unfavorable environmental conditions, C. elegans larvae undergo arrest and form dauer larvae that can attach to other animals as a parasitic strategy for survival. DAF-12 is an orphan nuclear hormone receptor that regulates dauer larva diapause, reproductive development, fat metabolism, and life...
| Schlagworte: | UPF-1404, (5alpha,25S)-3-oxo-cholest-7-en-26-oic acid |
| Anwendung: | DAF-12 inhibitor |
| CAS | 949004-12-0 |
| MW: | 414.6 D |
2.319,00 €
NEU
AR-C 155858 Artikelnummer: Cay14884-1
AR-C 155858 is an inhibitor of monocarboxylate transporter 1 (MCT1) and MCT2 (Kis = 2.3 and Xenopus oocytes expressing the human receptors). It is selective for MCT1 and MCT2 over MCT4 (Ki = >10 µM). AR-C 155858 inhibits L-lactate uptake in and proliferation of murine 4T1 breast cancer cells (IC50s = 25 and 20.2 nM,...
| Schlagworte: | 6-[(3,5-dimethyl-1H-pyrazol-4-yl)methyl]-5-[[(4S)-4-hydroxy-2-isoxazolidinyl]carbonyl]-3-methyl-1-(2-methylpropyl)-thieno[... |
| Anwendung: | Monocarboxylate transporter 1/2 inhibitor |
| CAS | 496791-37-8 |
| MW: | 461.5 D |
374,00 €
NEU
4(Z),7(Z),10(Z),13(Z)-Hexadecatetraenoic Acid-d5 Artikelnummer: Cay14894-25
4(Z),7(Z),10(Z),13(Z)-Hexadecatetraenoic acid-d5 contains five deuterium atoms at the 15, 15', 16, 16, and 16 positions. It is intended for use as an internal standard for the quantification of 4(Z),7(Z),10(Z),13(Z)-hexadecatetraenoic acid by GC- or LC-mass spectrometry. Hexadecatetraenoic acid (16:4 n-3) is an...
| Schlagworte: | (4Z,7Z,10Z,13Z)-hexadeca-4,7,10,13-tetraenoic-15,15',16,16,16-d5 acid |
| Anwendung: | Mass Spectrometry, Standard |
| MW: | 253.4 D |
42,00 €
NEU
KT185 Artikelnummer: Cay19113-50
KT185 is an orally bioavailable inhibitor of alpha/beta-hydrolase domain-containing protein 6 (ABHD6) with an IC50 value of 0.21 nM in a competitive activity-based protein profiling assay using Neuro2A membranes. It inhibits ABHD6 in a 2-arachidonoyl glycerol (2-AG, Cay-62160) hydrolysis assay (IC50 = 13.6 nM for...
| Schlagworte: | [4'-[1-[(2-phenyl-1-piperidinyl)carbonyl]-1H-1,2,3-triazol-4-yl][1,1'-biphenyl]-3-yl]-1-piperidinyl-methanone |
| Anwendung: | ABHD6 inhibitor |
| CAS | 1472640-86-0 |
| MW: | 519.6 D |
ab 94,00 €
NEU
Sulfamoxole Artikelnummer: Cay19537-50
Sulfamoxole is a sulfonamide antibiotic. It is inactive or weakly active against bacteria when used alone but acts synergistically with trimethoprim (Cay-16473) against a variety of bacteria in vitro, including strains of S. pyogenes, E. coli, and P. vulgaris when used at concentrations of 1.95-7.8, 0.12-1.95, and...
| Schlagworte: | NSC 683535, 4-amino-N-(4,5-dimethyl-2-oxazolyl)-benzenesulfonamide |
| Anwendung: | Sulfonamide antibiotic, Antibacterial, Folic acid biosynthesis inhibitor |
| CAS | 729-99-7 |
| MW: | 267.3 D |
ab 49,00 €
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