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Leupeptin (Ac-Leu-Leu-Arginal-hemisulfate)
Leupeptin (Ac-Leu-Leu-Arginal-hemisulfate)

Artikelnummer: 12136.25

Leupeptin, also known as N-acetyl-L-leucyl-L-leucyl-L-argininal, is a naturally occurring protease inhibitor that can inhibit cysteine, serine and threonine peptidases. It is often used during in vitro experiments when a specific enzymatic reaction is being studied. When cells are lysed for these studies, proteases,...
Anwendung: Inhibitor
CAS 103476-89-7
MW: 475.6
ab 83,00 €
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BB-Cl-Amidine
BB-Cl-Amidine

Artikelnummer: Cay17079-1

BB-Cl-Amidine is a modified version of Cl-amidine (Cay-10599) that retains the functional components but possesses a C-terminal benzimidazole group designed to limit proteolysis of the C-terminal amide. BB-Cl-Amidine irreversibly inactivates all four PAD subtypes (kinact/KI = 16,100, 4,100, 6,800, and 13,300...
Schlagworte: N-[(1S)-1-(1H-benzimidazol-2-yl)-4-[(2-chloro-1-iminoethyl)amino]butyl]-[1,1'-biphenyl]-4-carboxamide
Anwendung: PADI4 inhibitor
CAS 1802637-39-3
MW: 460 D
ab 69,00 €
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COVID-19 Forschung
Remdesivir
Remdesivir

Artikelnummer: Cay30354-5

Remdesivir is a prodrug form of the antiviral nucleoside analog GS-441524 (Cay-30469). Upon entry into cells, remdesivir is metabolized into the nucleotide triphosphate GS-441524. Remdesivir is active against Middle East respiratory syndrome coronavirus (MERS-CoV) and severe acute respiratory syndrome CoV (SARS-CoV)...
Schlagworte: GS-5734, N-[(S)-hydroxyphenoxyphosphinyl)-L-alanine, 2-ethylbutyl ester, 6-ester with...
Anwendung: GS-441524 prodrug, SARS type antiviral
CAS 1809249-37-3
MW: 602.6 D
ab 110,00 €
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Interferon beta1a, human recombinant (rHuIFN-beta1a-CHO)
Interferon beta1a, human recombinant (rHuIFN-beta1a-CHO)

Artikelnummer: 86421.20

Has antiviral, antibacterial and anticancer activities. (www.uniprot.org) Produced in CHO cells. Single, glycosylated polypeptide chain containing 166 amino acids. The specific activity as determined in a viral resistance assay was found to be 270 x 106 IU/ mg.
Schlagworte: Leukocyte interferon, B cell interferon, Type I interferon, IFNB1, IFB, IFF, IFNB, IFN-b 1a, MGC96956
Anwendung: Cell Culture
Reaktivität: Human
MW: 22.5 kD
ab 71,00 €
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Anti-RbBP5
Anti-RbBP5

Artikelnummer: A300-109A

Protein function: In embryonic stem (ES) cells, plays a crucial role in the differentiation potential, particularly along the neural lineage, regulating gene induction and H3 'Lys-4' methylation at key developmental loci, including that mediated by retinoic acid. Does not affect ES cell self-renewal. Component or...
Schlagworte: Anti-RBQ3, Anti-RBBP5, Anti-RBBP-5, Anti-Retinoblastoma-binding protein 5, Anti-Retinoblastoma-binding protein RBQ-3
Anwendung: WB, IP, IHC, ICC, ChIP, ChIP-chip
Reaktivität: Human
ab 125,00 €
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Anti-p73
Anti-p73

Artikelnummer: A300-126A

Protein function: Participates in the apoptotic response to DNA damage. Isoforms containing the transactivation domain are pro-apoptotic, isoforms lacking the domain are anti-apoptotic and block the function of p53 and transactivating p73 isoforms. May be a tumor suppressor protein. [The UniProt Consortium]
Schlagworte: Anti-P73, Anti-TP73, Anti-Tumor protein p73, Anti-p53-related protein, Anti-p53-like transcription factor
Anwendung: WB, IP
Reaktivität: Human
ab 125,00 €
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COVID-19 Forschung
SARS-CoV-2 Inhibitor Screening Kit
SARS-CoV-2 Inhibitor Screening Kit

Artikelnummer: AG-48B-0001-KI01

To screen compounds that inhibit the binding of the viral protein SARS-CoV-2 Spike Protein (RBD) to its human receptor ACE2. Coronaviruses (CoVs) are enveloped non-segmented positive-sense single-stranded RNA viruses and can infect respiratory, gastrointestinal, hepatic and central nervous system of human and many...
Schlagworte: COVID-19 Inhibitor Screening Kit, 2019-nCoV Inhibitor Screening Kit, 2019-nCoV Spike Protein S1 (RBD)/ACE2 Inhibitor...
Anwendung: Compound Screening
Reaktivität: Human
715,00 €
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Aniline-13C6
Aniline-13C6

Artikelnummer: Cay30523-1

Aniline-13C6 is a building block. It has been used in the synthesis of 13C6-labeled derivatives of tryptophan and indole, as well as 13C6-labeled benzimidazoles.
Schlagworte: Benzenamine-13C6, benzenamine-1,2,3,4,5,6-13C6
Anwendung: Building block
CAS 100849-37-4
MW: 99.1 D
ab 207,00 €
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Ionomycin (calcium salt)
Ionomycin (calcium salt)

Artikelnummer: Cay11932-1

Ionomycin is a selective calcium ionophore derived from S. conglobatus that mobilizes intracellular calcium stores. It is used as a research tool to raise the intracellular level of calcium, to study calcium transport across biological membranes, and to stimulate the intracellular production of cytokines. This...
Schlagworte: 11,19R,21S-trihydroxy-4R,6S,8S,12R,14R,18R,20S-heptamethyl-22-[octahydro-5'S-[1R-hydroxyethyl]-2S,5'-dimethyl[2,2'R-bifura...
Anwendung: Calcium ionophore
CAS 56092-82-1
MW: 747.1 D
ab 32,00 €
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Arachidonic Acid-d11
Arachidonic Acid-d11

Artikelnummer: Cay10006758-100

Arachidonic acid-d11 contains 11 deuterium atoms at the 16, 16, 17, 17, 18, 18, 19, 19, 20, 20, and 20 positions. It is intended for use as an internal standard for the quantification of arachidonic acid (Cay-90010) by GC- or LC-mass spectrometry. Arachidonic acid is an essential fatty acid and a precursor for all...
Schlagworte: AA-d11, 5Z,8Z,11Z,14Z-eicosatetraenoic-16,16,17,17,18,18,19,19,20,20,20-d11 acid
Anwendung: GC-MS, LC-MS, Internal standard
MW: 315.5 D
ab 48,00 €
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-10 %
Angebot
Estradiol ELISA Kit
Estradiol ELISA Kit

Artikelnummer: Cay501890-96

Estradiol is a steroid hormone produced from testosterone via the aromatase system in the granulosa cells of ovarian follicles. It is instrumental in the development of secondary sex characteristics at puberty and in the menstrual cycle. Plasma levels of estradiol peak during the follicular phase of the menstrual...
Schlagworte: 17beta-Estradiol, 17beta-Oestradiol, E2, Estradiol EIA Kit, beta-Estradiol
Anwendung: Competitive ELISA
250,00 € ab 225,00 €
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Imipenem (hydrate)
Imipenem (hydrate)

Artikelnummer: Cay16039-100

Imipenem is an intravenous beta-lactam antibiotic effective against a wide range of Gram-positive and Gram-negative bacteria (MICs range from 0.5-2 µg/ml for E. cloacae and P. aeruginosa), including several multi-drug resistant bacterial species. Imipenem acts by interfering with bacterial cell wall synthesis.
Schlagworte: N-Formimidoyl Thienamycin,...
Anwendung: Antibacterial antibiotic, Peptidoglycan biosynthesis inhibitor
CAS 74431-23-5
MW: 317.4 D
ab 57,00 €
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