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Anhydrotetracycline (hydrochloride)
Anhydrotetracycline (hydrochloride)

Artikelnummer: Cay10009542-100

The tetracycline repressor (TetR) is a transcriptional regulator which normally binds tightly to its palindromic tetO operator DNA, blocking gene expression. Tet causes the repressor to dissociate from the DNA, allowing transcription to occur. A novel reverse TetR (revTetR) requires tetracycline as a co-repressor to...
Schlagworte: 4-(dimethylamino)-1,4S,4aS,5,12,12aS-hexahydro-3,10,11,12a-tetrahydroxy-6-methyl-1,12-dioxo-2-naphthacenecarboxamide,...
Anwendung: Antibiotic
CAS 13803-65-1
MW: 462.9 D
ab 45,00 €
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(25S)-Delta7-Dafachronic Acid
(25S)-Delta7-Dafachronic Acid

Artikelnummer: Cay14101-100

During unfavorable environmental conditions, C. elegans larvae undergo arrest and form dauer larvae that can attach to other animals as a parasitic strategy for survival. DAF-12 is an orphan nuclear hormone receptor that regulates dauer larva diapause, reproductive development, fat metabolism, and life...
Schlagworte: UPF-1404, (5alpha,25S)-3-oxo-cholest-7-en-26-oic acid
Anwendung: DAF-12 inhibitor
CAS 949004-12-0
MW: 414.6 D
ab 332,00 €
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Malformin C
Malformin C

Artikelnummer: Cay21613-1

Malformin C is a natural fungus-derived bicyclic pentapeptide that has antibacterial properties, particularly against species of Bacillus. Malformin C potently blocks the ability of bleomycin (Cay-13877) to induce G2 arrest in human T-cell leukemia-derived Jurkat cells (IC50 = 0.9 nM). It less potently abrogates...
Schlagworte: Malformin B1b, cyclo(D-cysteinyl-D-cysteinyl-L-valyl-D-leucyl-L-leucyl), cyclic (1->2)-disulfide
Anwendung: Antibacterial
CAS 59926-78-2
MW: 529.7 D
ab 232,00 €
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-10 %
Aktion
Lipid Hydroperoxide (LPO) Assay Kit (96 well)
Lipid Hydroperoxide (LPO) Assay Kit (96 well)

Artikelnummer: Cay705003-96

Quantification of lipid peroxidation is essential to assess the role of oxidative injury in pathophysiological disorders. Lipid peroxidation results in the formation of highly reactive and unstable hydroperoxides of both saturated and unsaturated lipids. Our Lipid Hydroperoxide Assay Kit measures the hydroperoxides...
Anwendung: LPO quantification
744,00 € 669,60 €
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FAM-FLIVO(R) In Vivo Poly Caspase Assay (small)
FAM-FLIVO(R) In Vivo Poly Caspase Assay (small)

Artikelnummer: ICT-980

This kit makes use of an injectable green fluorescent and cell permeable probe used to quantitate caspase activity in vivo. Only cells undergoing apoptosis will fluoresce. It is an ideal reagent to asses the efficacy of chemotherapy in animals.
Anwendung: FM, FC, Apoptosis detection
242,00 €
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FAM-FLIVO(R) In Vivo Poly Caspase Assay (large)
FAM-FLIVO(R) In Vivo Poly Caspase Assay (large)

Artikelnummer: ICT-981

This kit makes use of an injectable green fluorescent and cell permeable probe used to quantitate caspase activity in vivo. Only cells undergoing apoptosis will fluoresce. It is an ideal reagent to asses the efficacy of chemotherapy in animals.
Anwendung: FM, FC, Apoptosis detection
663,00 €
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SR-FLIVO(R) In vivo Poly Caspase Assay (small)
SR-FLIVO(R) In vivo Poly Caspase Assay (small)

Artikelnummer: ICT-982

This kit makes use of an injectable red fluorescent and cell permeable probe used to quantitate caspase activity in vivo. Only cells undergoing apoptosis will fluoresce. Ideal reagent to asses the efficacy of chemotherapy.
Anwendung: FM, FC, Apoptosis detection
242,00 €
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Plant Sterol Mixture, (qualitative)
Plant Sterol Mixture, (qualitative)

Artikelnummer: MTY-1119

Source: natural, plant. Solvent: chloroform. Analytical Method: TLC, GC. Solubility: Chloroform. Concentration: 25 mg/ml
Schlagworte: Plant Sterol Mixture, (qualitative)
Anwendung: Sterols - Plant Sterols and Steryl Glucosides
176,00 €
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NALP3 (delPYD), FLAG-Tag
NALP3 (delPYD), FLAG-Tag

Artikelnummer: BPS-100454

Human NLR Family Pyrin Domain Containing 3 (NLRP3), also known as NALP3, Cold Autoinflammatory Syndrome 1 Protein (CIAS1), cryopyrin and PYPAF1, Genbank Accession No. NM_004895, a.a. 134-1036(end) with N-terminal FLAG-tag, expressed in a HEK293 expression system. MW = 105 kDa.
Schlagworte: NLRP3, C1orf7, CLR1.1, Cryopyrin, Caterpiller protein 1.1, PYRIN-containing APAF1-like protein 1, Angiotensin/vasopressin...
Anwendung: Immunotherapy studies
Reaktivität: Human
MW: 120 kD
618,00 €
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NEK7, His-Tag
NEK7, His-Tag

Artikelnummer: BPS-100476

Human NEK7, also known as NIMA Related Kinase 7, GenBank Accession No. NM_133494, a.a. 2-302 (end), with N-terminal His-tag, expressed in a HEK293 cell expression system. MW=37 kDa.
Schlagworte: NEK7, EC=2.7.11.1, NimA-related protein kinase 7, Never in mitosis A-related kinase 7, Serine/threonine-protein kinase Nek7
Anwendung: Kinase assays
Reaktivität: Human
MW: 37 kD
474,00 €
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Estradiol ELISA Kit
Estradiol ELISA Kit

Artikelnummer: Cay501890-96

Estradiol is a steroid hormone produced from testosterone via the aromatase system in the granulosa cells of ovarian follicles. It is instrumental in the development of secondary sex characteristics at puberty and in the menstrual cycle. Plasma levels of estradiol peak during the follicular phase of the menstrual...
Schlagworte: 17beta-Estradiol, 17beta-Oestradiol, E2, Estradiol EIA Kit, beta-Estradiol
Anwendung: Competitive ELISA
ab 250,00 €
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Oligomycin Complex
Oligomycin Complex

Artikelnummer: Cay11341-5

Oligomycins are macrolides created by Streptomyces species that can be toxic to other organisms through their ability to inhibit mitochondrial membrane-bound ATP synthases. The mitochondrial F1FO ATP synthase can switch to an ATP hydrolase during ischemia, so that, under these conditions, inhibition by oligomycins...
Anwendung: ATP synthase inhibitor, Apoptosis inducer
CAS 1404-19-9
MW: 789,3 D
ab 32,00 €
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