Referenzstandards

Häufig wird die Bedeutung von Referenzstandards bei der Durchführung quantitativer Assays übersehen. Ein gut charakterisierter Referenzstandard in Kombination mit einer robusten Methodik liefert genaue und präzise analytische Ergebnisse.

Häufig wird die Bedeutung von Referenzstandards bei der Durchführung quantitativer Assays übersehen. Ein gut charakterisierter Referenzstandard in Kombination mit einer robusten Methodik liefert... mehr erfahren »
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Referenzstandards

Häufig wird die Bedeutung von Referenzstandards bei der Durchführung quantitativer Assays übersehen. Ein gut charakterisierter Referenzstandard in Kombination mit einer robusten Methodik liefert genaue und präzise analytische Ergebnisse.

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6-keto Prostaglandin F1alpha-d4
6-keto Prostaglandin F1alpha-d4

Artikelnummer: Cay315210-25

6-keto Prostaglandin F1alpha-d4 (6-keto PGF1alpha-d4) contains four deuterium atoms at the 3, 3', 4, and 4' positions. It is intended for use as an internal standard for the quantification of 6-keto PGF1alpha (Cay-15210) by GC- or LC-MS. 6-keto PGF1alpha is the inactive, non-enzymatic hydrolysis product of PGI2....
Schlagworte: 6-keto PGF1alpha-d4, 6-oxo-9alpha,11alpha,15S-trihydroxy-prost-13E-en-1-oic-3,3,4,4-d4 acid
Anwendung: Standard
CAS 82414-64-0
MW: 374.5 D
ab 65,00 €
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2-Arachidonoyl Glycerol-d5
2-Arachidonoyl Glycerol-d5

Artikelnummer: Cay362162-100

2-Arachidonoyl glycerol-d5 (2-AG-d5) contains five deuterium atoms at the 1, 1, 2, 3, and 3 positions of the glycerol moiety. It is intended for use as an internal standard for the quantification of 2-AG by GC- or LC-mass spectrometry. 2-Arachidonoyl glycerol (2-AG) is an endogenous agonist of the CB1 receptor....
Schlagworte: 2-AG-d5, 5Z,8Z,11Z,14Z-eicosatetraenoic acid, 2-glycerol-1,1,2,3,3-d5 ester
Anwendung: Standard
MW: 383.6 D
ab 65,00 €
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alpha-Bungarotoxin
alpha-Bungarotoxin

Artikelnummer: Cay16385-1

alpha-Bungarotoxin is a snake venom-derived toxin that irreversibly binds nicotinic acetylcholine receptors (Ki = ~2.5 µM in rat) present in skeletal muscle, blocking action of acetylcholine at the postsynaptic membrane and leading to paralysis. It has been widely used to characterize activity at the neuromuscular...
Schlagworte: alpha-Bgt, alpha-BTX, alpha-bungarotoxin
Anwendung: Irreversible nicotinic acetylcholine receptor blocker
CAS 11032-79-4
MW: 7984.2 D
187,00 €
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MPP+ Iodide
MPP+ Iodide

Artikelnummer: Cay16958-50

MPP+ is an active metabolite of MPTP (Cay-16377), a neurotoxin used to cause selective destruction of dopaminergic neurons in animal models of parkinsonism. MPP+ induces neurotoxicity primarily by inhibiting complex I of the mitochondrial electron transport chain, resulting in ATP depletion and increased oxidative...
Schlagworte: N-Methyl-4-Phenylpyridinium Iodide, 1-methyl-4-phenyl-pyridinium, monoiodide
Anwendung: Neurotoxin, Oxidative stress inducer
CAS 36913-39-0
MW: 297.1 D
ab 48,00 €
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Thromboxane B2 MaxSpec(R) Standard
Thromboxane B2 MaxSpec(R) Standard

Artikelnummer: Cay10007237-100

Thromboxane B2 (TXB2) is a stable, biologically inert metabolite formed from the non-enzymatic hydrolysis of TXA2, which has a half-life of about 30 seconds. Urinary analysis of TXB2 accurately reflects intrarenal TXA2 synthesis, while measurement of 11-dehydro and 2,3-dinor TX metabolites gives the best estimate of...
Schlagworte: TXB2, 9alpha,11,15S-trihydroxythromba-5Z,13E-dien-1-oic acid
Anwendung: Bioactive lipid assays
CAS 54397-85-2
MW: 370.5 D
119,00 €
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Apicidin
Apicidin

Artikelnummer: Cay10575-1

Histone acetyltransferase and histone deacetylase (HDAC) activity regulates the reversible acetylation of lysine residues within histone tails, which results in either transcriptional activation or repression of nearby genes. Compounds that modulate this activity are of interest in cancer chemotherapeutics as well...
Schlagworte: OSI 2040, cyclo[(2S)-2-amino-8-oxodecanoyl-1-methoxy-L-tryptophyl-L-isoleucyl-(2R)-2-piperidinecarbonyl]
Anwendung: HDAC inhibitor
CAS 183506-66-3
MW: 623.8 D
ab 59,00 €
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Prostaglandin E2-d9
Prostaglandin E2-d9

Artikelnummer: Cay10581-50

PGE2-d9 contains nine deuterium atoms at the 17, 17', 18, 18', 19, 19', 20, 20, and 20' positions. It is intended for use as an internal standard for the quantification of PGE2 by GC- or LC-mass spectrometry (MS). PGE2 is one of the primary cyclooxygenase products of arachidonic acid and one of the most widely...
Schlagworte: Dinoprostone-d9, PGE2-d9, 9-oxo-11alpha,15S-dihydroxy-prosta-5Z,13E-dien-1-oic-17,17,18,18,19,19,20,20,20-d9 acid
Anwendung: Standard
CAS 1356347-42-6
MW: 361.5 D
ab 64,00 €
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Cytochalasin B
Cytochalasin B

Artikelnummer: Cay11328-10

Cytochalasin B is a cell-permeable mycotoxin which binds to the barbed end of actin, reversibly inhibiting the elongation and shortening of actin filaments. By disrupting actin polymerization, cytochalasin B blocks diverse cellular functions, including cell division, migration, phagocytosis, exocytosis, chemotaxis,...
Schlagworte: NSC 107658, Phomin,...
Anwendung: Mycotoxin
CAS 14930-96-2
MW: 479.6 D
ab 44,00 €
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Prostaglandin D2-d4
Prostaglandin D2-d4

Artikelnummer: Cay312010-25

Prostaglandin D2-d4 (PGD2-d4) contains four deuterium atoms at the 3, 3', 4, and 4' positions. It is intended for use as an internal standard for the quantification of PGD2 by GC- or LC-mass spectrometry. PGD2 is the major eicosanoid product of mast cells and is released in large quantities during allergic and...
Schlagworte: PGD2-d4, 9alpha,15S-dihydroxy-11-oxo-prosta-5Z,13E-dien-1-oic-3,3,4,4-d4 acid
Anwendung: Standard
CAS 211105-29-2
MW: 356.5 D
ab 94,00 €
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Prostaglandin E2-d4
Prostaglandin E2-d4

Artikelnummer: Cay314010-50

Prostaglandin E2-d4 (PGE2-d4) contains four deuterium atoms at the 3, 3', 4, and 4' positions. It is intended for use as an internal standard for the quantification of PGE2 by GC- or LC-mass spectrometry. PGE2 is one of the primary cyclooxygenase products of arachidonic acid and one of the most widely investigated...
Schlagworte: Dinoprostone-d4, PGE2-d4, 9-oxo-11alpha,15S-dihydroxy-prosta-5Z,13E-dien-1-oic-3,3,4,4-d4 acid
Anwendung: Standard
CAS 34210-10-1
MW: 356.5 D
ab 67,00 €
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Prostaglandin F2alpha-d4
Prostaglandin F2alpha-d4

Artikelnummer: Cay316010-25

Prostaglandin F2alpha-d4 (PGF2alpha-d4) contains four deuterium atoms at the 3, 3', 4, and 4' positions. It is intended for use as an internal standard for the quantification of PGF2alpha (Cay-16010) by GC- or LC-mass spectrometry. PGF2alpha is a widely distributed prostaglandin occurring in many species. It causes...
Schlagworte: Dinoprost-d4, PGF2alpha-d4, 9alpha,11alpha,15S-trihydroxy-prosta-5Z,13E-dien-1-oic-3,3,4,4-d4 acid
Anwendung: Standard
CAS 34210-11-2
MW: 358.5 D
ab 44,00 €
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13(S)-HODE-d4
13(S)-HODE-d4

Artikelnummer: Cay338610-25

13(S)-HODE-d4 contains four deuterium atoms at the 9, 10, 12, and 13 positions. It is intended for use as an internal standard for the quantification of 13(S)-HODE by GC- or LC-mass spectrometry. 13(S)-HODE is produced by incubation of linoleic acid with plant and mammalian lipoxygenases. It has been shown to...
Schlagworte: 13S-hydroxy-9Z,11E-octadecadienoic-9,10,12,13-d4 acid
Anwendung: Standard
CAS 139408-39-2
MW: 300.5 D
ab 138,00 €
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