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alpha-Bungarotoxin Artikelnummer: Cay16385-1
alpha-Bungarotoxin is a snake venom-derived toxin that irreversibly binds nicotinic acetylcholine receptors (Ki = ~2.5 µM in rat) present in skeletal muscle, blocking action of acetylcholine at the postsynaptic membrane and leading to paralysis. It has been widely used to characterize activity at the neuromuscular...
| Schlagworte: | alpha-Bgt, alpha-BTX, alpha-bungarotoxin |
| Anwendung: | Irreversible nicotinic acetylcholine receptor blocker |
| CAS | 11032-79-4 |
| MW: | 7984.2 D |
187,00 €
Thromboxane B2 MaxSpec(R) Standard Artikelnummer: Cay10007237-100
Thromboxane B2 (TXB2) is a stable, biologically inert metabolite formed from the non-enzymatic hydrolysis of TXA2, which has a half-life of about 30 seconds. Urinary analysis of TXB2 accurately reflects intrarenal TXA2 synthesis, while measurement of 11-dehydro and 2,3-dinor TX metabolites gives the best estimate of...
| Schlagworte: | TXB2, 9alpha,11,15S-trihydroxythromba-5Z,13E-dien-1-oic acid |
| Anwendung: | Bioactive lipid assays |
| CAS | 54397-85-2 |
| MW: | 370.5 D |
119,00 €
Prostaglandin F2alpha MaxSpec(R) Standard Artikelnummer: Cay10007221-100
Prostaglandin F2alpha (PGF2alpha) is a widely distributed PG occurring in many species. It causes contraction of vascular, bronchial, intestinal, and myometrial smooth muscle, and also exhibits potent luteolytic activity. PGF2alpha exerts its receptor mediated physiological activity at 50-100 nM. Maximal ovine...
| Schlagworte: | 9alpha,11alpha,15S-trihydroxy-prosta-5Z,13E-dien-1-oic acid |
| Anwendung: | Quantitative MS |
| CAS | 551-11-1 |
| MW: | 354.5 D |
75,00 €
6-keto Prostaglandin F1alpha MaxSpec(R) Standard Artikelnummer: Cay10007219-100
6-keto Prostaglandin F1alpha (6-keto PGF1alpha) is the inactive, non-enzymatic hydrolysis product of PGI2 (Cay-18220). 6-keto PGF1alpha serves as a useful marker of PGI2 biosynthesis in vivo. When [3H]-PGI2 is injected into healthy human males, 6.6% of the radioactivity is recovered from urine as [3H]-6-keto...
| Schlagworte: | 6-oxo-9alpha,11alpha,15S-trihydroxy-prost-13E-en-1-oic acid |
| Anwendung: | Quantitative MS |
| CAS | 58962-34-8 |
| MW: | 370.5 D |
150,00 €
Prostaglandin E2 MaxSpec(R) Standard Artikelnummer: Cay10007211-100
Prostaglandin E2 (PGE2) is one of the primary COX products of arachidonic acid (Cay-90010) and one of the most widely investigated PGs. Its activity influences inflammation, fertility and parturition, gastric mucosal integrity, and immune modulation. The effects of PGE2 are transduced by at least four distinct...
| Schlagworte: | Dinoprostone, PGE2, 9-oxo-11alpha,15S-dihydroxy-prosta-5Z,13E-dien-1-oic acid |
| Anwendung: | Bioactive lipid assays |
| CAS | 363-24-6 |
| MW: | 352.5 D |
62,00 €
15(S)-HETE MaxSpec(R) Standard Artikelnummer: Cay10007251-100
15(S)-HETE is a major arachidonic acid metabolite from the 15-lipoxygenase pathway. In mammals, 15(S)-HETE is synthesized in the respiratory epithelium, leukocytes, and reticulocytes. 15(S)-HETE is present in µg/ml concentrations in the nasal secretions of allergic rhinitis. 15(S)-HETE MaxSpec(R) standard is a...
| Schlagworte: | 15(S)-HETE Lipid Maps MS Standard, 15S-hydroxy-5Z,8Z,11Z,13E-eicosatetraenoic acid |
| Anwendung: | Bioactive lipid assays |
| CAS | 54845-95-3 |
| MW: | 320.5 D |
182,00 €
SPM D-series LC-MS Mixture Artikelnummer: Cay18702-1
This mixture contains several D-series resolvins (specialized pro-resolving mediators, SPMs) and their precursor, docosahexaenoic acid (DHA, Cay-90310). The mixture is supplied in an amber ampule in which the headspace has been purged with argon to prevent lipid oxidation. This product has been designed for direct...
| Schlagworte: | Specialized Pro-Resolving Mediator D-series LC-MS Mixture |
| Anwendung: | LC-MS, Calibrator / standard preparation |
407,00 €
Prostaglandin D2 MaxSpec(R) Standard Artikelnummer: Cay10007202-100
Prostaglandin D2 (PGD2) is the major eicosanoid product of mast cells and is released in large quantities during allergic and asthmatic anaphylaxis. Mastocytosis patients produce excessive amounts of PGD2, which causes vasodilation, flushing, hypotension, and syncopal episodes. PGD2 is also produced in the brain via...
| Schlagworte: | PGD2, 9alpha,15S-dihydroxy-11-oxo-prosta-5Z,13E-dien-1-oic acid |
| Anwendung: | Bioactive lipid assays |
| CAS | 41598-07-6 |
| MW: | 352.5 D |
90,00 €
Arachidonic Acid MaxSpec(R) Standard Artikelnummer: Cay10007268-1
Arachidonic acid is an essential fatty acid and a precursor for all prostaglandins, thromboxanes, and leukotrienes. Virtually all cellular arachidonic acid is esterified in membrane phospholipids where its presence is tightly regulated through multiple interconnected pathways. Free arachidonic acid is a transient,...
| Schlagworte: | AA, 5Z,8Z,11Z,14Z-eicosatetraenoic acid |
| Anwendung: | Quantitative MS standard |
| CAS | 506-32-1 |
| MW: | 304.5 D |
65,00 €
Prostaglandin E2-d4 MaxSpec(R) Standard Artikelnummer: Cay10007273-10
Prostaglandin E2-d4 (PGE2-d4) is intended for use as an internal standard for the quantification of PGE2 (Cay-14010) by GC- or LC-MS. PGE2 is one of the primary cyclooxygenase products of arachidonic acid (Cay-90010) and one of the most widely investigated prostaglandins. Its activity influences inflammation,...
| Schlagworte: | Dinoprostone-d4, PGE2-d4, 9-oxo-11alpha,15S-dihydroxy-prosta-5Z,13E-dien-1-oic-3,3,4,4-d4 acid |
| Anwendung: | Standard |
| MW: | 356.5 D |
112,00 €
Leukotriene B4 MaxSpec(R) Standard Artikelnummer: Cay10007240-10
Leukotriene B4 (LTB4) is a dihydroxy fatty acid derived from arachidonic acid through the 5-LO pathway. It promotes a number of leukocyte functions including aggregation, stimulation of ion fluxes, enhancement of lysosomal enzyme release, superoxide anion production, chemotaxis, and chemokinesis. In subnanomolar...
| Schlagworte: | LTB4, 5S,12R-dihydroxy-6Z,8E,10E,14Z-eicosatetraenoic acid |
| CAS | 71160-24-2 |
| MW: | 336.5 D |
204,00 €
(±)17-HDHA MaxSpec(R) Standard Artikelnummer: Cay10007223-100
(±)17-HDHA is an autoxidation product of docosahexaenoic acid (DHA, Cay-90310) in vitro. It is also produced from incubations of DHA in rat liver, brain, and intestinal microsomes. 17(S)-HDHA (Cay-10009799) could be produced by enzymatic oxidation of DHA using soybean lipoxygenase (LO) and is the putative product of...
| Schlagworte: | 17-hydroxy Docosahexaenoic Acid, 17-hydroxy DHA, (±)17-HDoHE |
| Anwendung: | Quantitative MS |
| CAS | 90780-52-2 |
| MW: | 354.5 D |
272,00 €