Referenzstandards

Häufig wird die Bedeutung von Referenzstandards bei der Durchführung quantitativer Assays übersehen. Ein gut charakterisierter Referenzstandard in Kombination mit einer robusten Methodik liefert genaue und präzise analytische Ergebnisse.

Häufig wird die Bedeutung von Referenzstandards bei der Durchführung quantitativer Assays übersehen. Ein gut charakterisierter Referenzstandard in Kombination mit einer robusten Methodik liefert... mehr erfahren »
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Referenzstandards

Häufig wird die Bedeutung von Referenzstandards bei der Durchführung quantitativer Assays übersehen. Ein gut charakterisierter Referenzstandard in Kombination mit einer robusten Methodik liefert genaue und präzise analytische Ergebnisse.

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alpha-Bungarotoxin
alpha-Bungarotoxin

Artikelnummer: Cay16385-1

alpha-Bungarotoxin is a snake venom-derived toxin that irreversibly binds nicotinic acetylcholine receptors (Ki = ~2.5 µM in rat) present in skeletal muscle, blocking action of acetylcholine at the postsynaptic membrane and leading to paralysis. It has been widely used to characterize activity at the neuromuscular...
Schlagworte: alpha-Bgt, alpha-BTX, alpha-bungarotoxin
Anwendung: Irreversible nicotinic acetylcholine receptor blocker
CAS 11032-79-4
MW: 7984.2 D
187,00 €
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Thromboxane B2 MaxSpec(R) Standard
Thromboxane B2 MaxSpec(R) Standard

Artikelnummer: Cay10007237-100

Thromboxane B2 (TXB2) is a stable, biologically inert metabolite formed from the non-enzymatic hydrolysis of TXA2, which has a half-life of about 30 seconds. Urinary analysis of TXB2 accurately reflects intrarenal TXA2 synthesis, while measurement of 11-dehydro and 2,3-dinor TX metabolites gives the best estimate of...
Schlagworte: TXB2, 9alpha,11,15S-trihydroxythromba-5Z,13E-dien-1-oic acid
Anwendung: Bioactive lipid assays
CAS 54397-85-2
MW: 370.5 D
119,00 €
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Prostaglandin F2alpha MaxSpec(R) Standard
Prostaglandin F2alpha MaxSpec(R) Standard

Artikelnummer: Cay10007221-100

Prostaglandin F2alpha (PGF2alpha) is a widely distributed PG occurring in many species. It causes contraction of vascular, bronchial, intestinal, and myometrial smooth muscle, and also exhibits potent luteolytic activity. PGF2alpha exerts its receptor mediated physiological activity at 50-100 nM. Maximal ovine...
Schlagworte: 9alpha,11alpha,15S-trihydroxy-prosta-5Z,13E-dien-1-oic acid
Anwendung: Quantitative MS
CAS 551-11-1
MW: 354.5 D
75,00 €
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6-keto Prostaglandin F1alpha MaxSpec(R) Standard
6-keto Prostaglandin F1alpha MaxSpec(R) Standard

Artikelnummer: Cay10007219-100

6-keto Prostaglandin F1alpha (6-keto PGF1alpha) is the inactive, non-enzymatic hydrolysis product of PGI2 (Cay-18220). 6-keto PGF1alpha serves as a useful marker of PGI2 biosynthesis in vivo. When [3H]-PGI2 is injected into healthy human males, 6.6% of the radioactivity is recovered from urine as [3H]-6-keto...
Schlagworte: 6-oxo-9alpha,11alpha,15S-trihydroxy-prost-13E-en-1-oic acid
Anwendung: Quantitative MS
CAS 58962-34-8
MW: 370.5 D
150,00 €
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Prostaglandin E2 MaxSpec(R) Standard
Prostaglandin E2 MaxSpec(R) Standard

Artikelnummer: Cay10007211-100

Prostaglandin E2 (PGE2) is one of the primary COX products of arachidonic acid (Cay-90010) and one of the most widely investigated PGs. Its activity influences inflammation, fertility and parturition, gastric mucosal integrity, and immune modulation. The effects of PGE2 are transduced by at least four distinct...
Schlagworte: Dinoprostone, PGE2, 9-oxo-11alpha,15S-dihydroxy-prosta-5Z,13E-dien-1-oic acid
Anwendung: Bioactive lipid assays
CAS 363-24-6
MW: 352.5 D
62,00 €
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15(S)-HETE MaxSpec(R) Standard
15(S)-HETE MaxSpec(R) Standard

Artikelnummer: Cay10007251-100

15(S)-HETE is a major arachidonic acid metabolite from the 15-lipoxygenase pathway. In mammals, 15(S)-HETE is synthesized in the respiratory epithelium, leukocytes, and reticulocytes. 15(S)-HETE is present in µg/ml concentrations in the nasal secretions of allergic rhinitis. 15(S)-HETE MaxSpec(R) standard is a...
Schlagworte: 15(S)-HETE Lipid Maps MS Standard, 15S-hydroxy-5Z,8Z,11Z,13E-eicosatetraenoic acid
Anwendung: Bioactive lipid assays
CAS 54845-95-3
MW: 320.5 D
182,00 €
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SPM D-series LC-MS Mixture
SPM D-series LC-MS Mixture

Artikelnummer: Cay18702-1

This mixture contains several D-series resolvins (specialized pro-resolving mediators, SPMs) and their precursor, docosahexaenoic acid (DHA, Cay-90310). The mixture is supplied in an amber ampule in which the headspace has been purged with argon to prevent lipid oxidation. This product has been designed for direct...
Schlagworte: Specialized Pro-Resolving Mediator D-series LC-MS Mixture
Anwendung: LC-MS, Calibrator / standard preparation
407,00 €
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Prostaglandin D2 MaxSpec(R) Standard
Prostaglandin D2 MaxSpec(R) Standard

Artikelnummer: Cay10007202-100

Prostaglandin D2 (PGD2) is the major eicosanoid product of mast cells and is released in large quantities during allergic and asthmatic anaphylaxis. Mastocytosis patients produce excessive amounts of PGD2, which causes vasodilation, flushing, hypotension, and syncopal episodes. PGD2 is also produced in the brain via...
Schlagworte: PGD2, 9alpha,15S-dihydroxy-11-oxo-prosta-5Z,13E-dien-1-oic acid
Anwendung: Bioactive lipid assays
CAS 41598-07-6
MW: 352.5 D
90,00 €
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Arachidonic Acid MaxSpec(R) Standard
Arachidonic Acid MaxSpec(R) Standard

Artikelnummer: Cay10007268-1

Arachidonic acid is an essential fatty acid and a precursor for all prostaglandins, thromboxanes, and leukotrienes. Virtually all cellular arachidonic acid is esterified in membrane phospholipids where its presence is tightly regulated through multiple interconnected pathways. Free arachidonic acid is a transient,...
Schlagworte: AA, 5Z,8Z,11Z,14Z-eicosatetraenoic acid
Anwendung: Quantitative MS standard
CAS 506-32-1
MW: 304.5 D
65,00 €
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Prostaglandin E2-d4 MaxSpec(R) Standard
Prostaglandin E2-d4 MaxSpec(R) Standard

Artikelnummer: Cay10007273-10

Prostaglandin E2-d4 (PGE2-d4) is intended for use as an internal standard for the quantification of PGE2 (Cay-14010) by GC- or LC-MS. PGE2 is one of the primary cyclooxygenase products of arachidonic acid (Cay-90010) and one of the most widely investigated prostaglandins. Its activity influences inflammation,...
Schlagworte: Dinoprostone-d4, PGE2-d4, 9-oxo-11alpha,15S-dihydroxy-prosta-5Z,13E-dien-1-oic-3,3,4,4-d4 acid
Anwendung: Standard
MW: 356.5 D
112,00 €
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Leukotriene B4 MaxSpec(R) Standard
Leukotriene B4 MaxSpec(R) Standard

Artikelnummer: Cay10007240-10

Leukotriene B4 (LTB4) is a dihydroxy fatty acid derived from arachidonic acid through the 5-LO pathway. It promotes a number of leukocyte functions including aggregation, stimulation of ion fluxes, enhancement of lysosomal enzyme release, superoxide anion production, chemotaxis, and chemokinesis. In subnanomolar...
Schlagworte: LTB4, 5S,12R-dihydroxy-6Z,8E,10E,14Z-eicosatetraenoic acid
CAS 71160-24-2
MW: 336.5 D
204,00 €
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(±)17-HDHA MaxSpec(R) Standard
(±)17-HDHA MaxSpec(R) Standard

Artikelnummer: Cay10007223-100

(±)17-HDHA is an autoxidation product of docosahexaenoic acid (DHA, Cay-90310) in vitro. It is also produced from incubations of DHA in rat liver, brain, and intestinal microsomes. 17(S)-HDHA (Cay-10009799) could be produced by enzymatic oxidation of DHA using soybean lipoxygenase (LO) and is the putative product of...
Schlagworte: 17-hydroxy Docosahexaenoic Acid, 17-hydroxy DHA, (±)17-HDoHE
Anwendung: Quantitative MS
CAS 90780-52-2
MW: 354.5 D
272,00 €
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