Produkte von Cayman

Cayman

Cayman Chemical Company ist ein Biotechunternehmen mit Sitz in Ann Arbor, Michigan, das mit seinen biochemischen Produkten Wissenschaftler weltweit bei der Arbeit in den Forschungsfeldern Krebs, NO Signalling, Neurologie, Apoptose, oxidativem Stress, Endokrinologie und vielen weiteren unterstützt. Cayman hat sich hierbei besonders auf die Herstellung von Assay Kits zum Nachweis von Eicosanoiden, freien Radikalen, zyklischen Nukleotiden, Zytokinen, Hormonen und Stickstoffmonoxid spezialisiert. Neben diesen Kits bietet Cayman ein breites Angebot an Biochemikalien, darunter Eicosanoiden, NO Reagenzien sowie eine Reihe thematisch verwandter Lipide, Fettsäuren, Enzyme und Antikörper.

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Thromboxane B2 ELISA Kit
Thromboxane B2 ELISA Kit

Artikelnummer: Cay501020-96

Thromboxane A2 (TXA2) is produced from arachidonic acid by many cells and causes irreversible platelet aggregation and contraction of vascular and bronchial smooth muscle. Like most lipid mediators, TXA2 is not a circulating hormone. It is formed in response to local stimuli and exerts its effects within a short distance of its biosynthesis. TXA2 is rapidly hydrolyzed...
Anwendung: ELISA
Format: Solid Phase
ab 357,00 €
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Herbst/Winter ELISA-Aktion
11-keto Testosterone ELISA Kit
11-keto Testosterone ELISA Kit

Artikelnummer: Cay582751-96

While testosterone is the primary androgenic male steroid found in mammals, 11-keto testosterone (11-KT) is a second key androgenic steroid found in fish. It occurs in males together with testosterone in amounts which vary from less than 1 ng/ml to as much as 50-100 ng/ml, depending on the species and the stage of the reproductive cycle. In the sea bass, testosterone...
Anwendung: ELISA
Format: Solid Phase
369,00 € ab 332,10 €
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DNA/RNA Oxidative Damage ELISA Kit
DNA/RNA Oxidative Damage ELISA Kit

Artikelnummer: Cay589320-96

Both DNA and RNA are damaged by oxidation during aging and in a variety of disease states including cancer. The repair processes that are initiated to correct this damage release multiple oxidized guanine species into the urine. Cayman Chemical has developed this immunoassay for the measurement of DNA/RNA oxidative damage that detects all three oxidized guanine species,...
Anwendung: ELISA
Format: Solid Phase
ab 619,00 €
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Glycolysis Cell-Based Assay Kit
Glycolysis Cell-Based Assay Kit

Artikelnummer: Cay600450-1

Cayman's Glycolysis Cell-Based Assay Kit provides a colorimetric method for detecting L-lactate, the end product of glycolysis, produced and secreted by cultured cells. In this assay, lactate dehydrogenase catalyzes the reaction between NAD+ and lactate, yielding pyruvate and NADH. The NADH directly reduces a tetrazolium salt (INT) to a colored formazan which absorbs between...
Anwendung: Extracellular L-lactate detection
Format: Homog.
313,00 €
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Glucose Uptake Cell-Based Assay Kit
Glucose Uptake Cell-Based Assay Kit

Artikelnummer: Cay600470-1

Glucose metabolism is a primary source of energy and biomaterials for the maintenance of cell homeostasis. Extra glucose is stored in the muscles and liver as glycogen which is hydrolyzed to glucose and released into the blood when needed. The rate of glucose uptake in cells is dynamic and tightly regulated by hormones and/or growth factors including insulin. Cancer cells...
Anwendung: Fluorescence
313,00 €
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Lipase Activity Assay Kit
Lipase Activity Assay Kit

Artikelnummer: Cay700640-96

Lipases perform essential roles in the digestion, transportation, and processing of dietary lipids by controlling the clearance of triglyceride-rich lipoproteins from the circulation. Manipulating lipolysis has therapeutic potential in the metabolic disorders frequently associated with obesity. Cayman's Lipase Activity Assay provides a fluorescence-based method for detecting...
Anwendung: Lipase activity detection
Format: Homog.
350,00 €
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Glutathione Assay Kit
Glutathione Assay Kit

Artikelnummer: Cay703002-96

Cayman's GSH assay kit utilizes a carefully optimized enzymatic recycling method, using glutathione reductase for the quantification of GSH. The sulfhydryl group of GSH reacts with DTNB (5,5'-dithio-bis-2-nitrobenzoic acid, Ellman's reagent) and produces a yellow colored 5-thio-2-nitrobenzoic acid (TNB). The mixed disulfide, GSTNB (between GSH and TNB) that is concomitantly...
Anwendung: GSH quantification
Format: Homog.
ab 288,00 €
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19(S)-HETE
19(S)-HETE

Artikelnummer: Cay10007766-25

19-HETE is one of the major cytochrome P450 (CYP450) metabolites of arachidonic acid that is released from the kidney in response to angiotensin II. When formed by the CYP2E1 isoform, 19-HETE is composed of 70% and 30% of the (S) and (R) stereoisomers, respectively. Both 19(S)- and 19(R)-HETE are potent vasodilators of renal preglomerular vessels. 19(S)-HETE stimulates both...
Anwendung: Bioactive lipid assays
CAS 115461-40-0
MW: 320.5 D
Reinheit: >98%
Format: Solution
ab 150,00 €
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Resolvin D1
Resolvin D1

Artikelnummer: Cay10012554-25

Resolvins are a family of potent lipid mediators derived from both eicosapentaenoic acid (EPA, Cay-90110) and docosahexaenoic acid (DHA, Cay-90310). In addition to being anti-inflammatory, resolvins promote the resolution of the inflammatory response back to a non-inflamed state. Resolvin D1 (RvD1) is produced physiologically from the sequential oxygenation of DHA by 15- and...
Anwendung: Bioactive lipid assays
CAS 872993-05-0
MW: 376.5 D
Reinheit: >95%
Format: Solution
ab 157,00 €
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(±)11(12)-DiHET
(±)11(12)-DiHET

Artikelnummer: Cay51511-25

Epoxide hydrolases convert the EETs into vicinal diols, with the concurrent loss of much of their biological activity. (±)11(12)-DiHET relaxes U-46619 (Cay-16450)-contracted artery rings with approximately 70% of the magnitude of (±)11(12)-EET (Cay-50511).
Anwendung: Bioactive lipid studies
MW: 338.5 D
Reinheit: >98%
Format: Solution
ab 93,00 €
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Resolvin D2
Resolvin D2

Artikelnummer: Cay10007279-10

Resolvins are a family of potent lipid mediators derived from both eicosapentaenoic acid (EPA, Cay-90110) and docosahexaenoic acid (DHA, Cay-90310). In addition to being anti-inflammatory, resolvins promote the resolution of the inflammatory response back to a non-inflamed state. Resolvin D2 (RvD2) is produced physiologically from the sequential oxygenation of DHA by 15- and...
Anwendung: Lipid mediator
CAS 810668-37-2
MW: 376.5 D
Reinheit: >95%
Format: Solution
ab 157,00 €
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Latrunculin A
Latrunculin A

Artikelnummer: Cay10010630-50

Actin disruption is used to study cell functions in vitro (e.g., migration, endocytosis) and in vivo (e.g., tumor cell invasion). Latrunculin A is a bioactive 2-thiazolidinone macrolide derived from sponges that sequesters G-actin and prevents F-actin assembly. It binds monomeric actin with 1:1 stoichiometry and can be used to block actin polymerization both in vitro (Kd =...
Anwendung: Actin polymerization inhibitor
CAS 76343-93-6
MW: 421.6 D
Reinheit: >98%
Format: Solution
ab 44,00 €
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