Produkte von Cayman Chemical

Cayman

Cayman Chemical Company ist ein Biotechunternehmen mit Sitz in Ann Arbor, Michigan, das mit seinen biochemischen Produkten Wissenschaftler weltweit bei der Arbeit in den Forschungsfeldern Krebs, NO Signalling, Neurologie, Apoptose, oxidativem Stress, Endokrinologie und vielen weiteren unterstützt. Cayman Chemical hat sich hierbei besonders auf die Herstellung von Assay-Kits zum Nachweis von Eicosanoiden, freien Radikalen, zyklischen Nukleotiden, Zytokinen, Hormonen und Stickstoffmonoxid spezialisiert. Neben diesen Kits bietet Cayman Chemical ein breites Angebot an Biochemikalien, darunter Eicosanoiden, NO Reagenzien sowie eine Reihe thematisch verwandter Lipide, Fettsäuren, Enzyme und Antikörper.

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(25S)-Delta7-Dafachronic Acid
(25S)-Delta7-Dafachronic Acid

Artikelnummer: Cay14101-100

During unfavorable environmental conditions, C. elegans larvae undergo arrest and form dauer larvae that can attach to other animals as a parasitic strategy for survival. DAF-12 is an orphan nuclear hormone receptor that regulates dauer larva diapause, reproductive development, fat metabolism, and life...
Schlagworte: UPF-1404, (5alpha,25S)-3-oxo-cholest-7-en-26-oic acid
Anwendung: DAF-12 inhibitor
CAS 949004-12-0
MW: 414.6 D
ab 332,00 €
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Malformin C
Malformin C

Artikelnummer: Cay21613-1

Malformin C is a natural fungus-derived bicyclic pentapeptide that has antibacterial properties, particularly against species of Bacillus. Malformin C potently blocks the ability of bleomycin (Cay-13877) to induce G2 arrest in human T-cell leukemia-derived Jurkat cells (IC50 = 0.9 nM). It less potently abrogates...
Schlagworte: Malformin B1b, cyclo(D-cysteinyl-D-cysteinyl-L-valyl-D-leucyl-L-leucyl), cyclic (1->2)-disulfide
Anwendung: Antibacterial
CAS 59926-78-2
MW: 529.7 D
ab 232,00 €
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-10 %
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Lipid Hydroperoxide (LPO) Assay Kit (96 well)
Lipid Hydroperoxide (LPO) Assay Kit (96 well)

Artikelnummer: Cay705003-96

Quantification of lipid peroxidation is essential to assess the role of oxidative injury in pathophysiological disorders. Lipid peroxidation results in the formation of highly reactive and unstable hydroperoxides of both saturated and unsaturated lipids. Our Lipid Hydroperoxide Assay Kit measures the hydroperoxides...
Anwendung: LPO quantification
744,00 € 669,60 €
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Anhydrotetracycline (hydrochloride)
Anhydrotetracycline (hydrochloride)

Artikelnummer: Cay10009542-50

The tetracycline repressor (TetR) is a transcriptional regulator which normally binds tightly to its palindromic tetO operator DNA, blocking gene expression. Tet causes the repressor to dissociate from the DNA, allowing transcription to occur. A novel reverse TetR (revTetR) requires tetracycline as a co-repressor to...
Schlagworte: 4-(dimethylamino)-1,4S,4aS,5,12,12aS-hexahydro-3,10,11,12a-tetrahydroxy-6-methyl-1,12-dioxo-2-naphthacenecarboxamide,...
Anwendung: Antibiotic
CAS 13803-65-1
MW: 462.9 D
ab 45,00 €
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Estradiol ELISA Kit
Estradiol ELISA Kit

Artikelnummer: Cay501890-96

Estradiol is a steroid hormone produced from testosterone via the aromatase system in the granulosa cells of ovarian follicles. It is instrumental in the development of secondary sex characteristics at puberty and in the menstrual cycle. Plasma levels of estradiol peak during the follicular phase of the menstrual...
Schlagworte: 17beta-Estradiol, 17beta-Oestradiol, E2, Estradiol EIA Kit, beta-Estradiol
Anwendung: Competitive ELISA
ab 250,00 €
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Human Fibrinogen (PAD4 Citrullinated)
Human Fibrinogen (PAD4 Citrullinated)

Artikelnummer: Cay400076-1

Fibrinogen is a plasma clotting factor composed of three different polypeptide chains (alpha, beta and gamma). Under chronic inflammatory conditions, fibrinogen can be acted upon by the enzyme peptidylarginine deiminase 4 (PAD4), converting specific arginine residues to citrulline. Patients with rheumatoid arthritis...
Schlagworte: cFBG, FGA, Fibrinopeptide A, Fibrinogen alpha chain, FGB, Fibrinopeptide B, Fibrinogen beta chain, FGG, PRO2061,...
Anwendung: WB
560,00 €
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Lipase Activity Assay Kit
Lipase Activity Assay Kit

Artikelnummer: Cay700640-96

Lipases perform essential roles in the digestion, transportation, and processing of dietary lipids by controlling the clearance of triglyceride-rich lipoproteins from the circulation. Manipulating lipolysis has therapeutic potential in the metabolic disorders frequently associated with obesity. Cayman's Lipase...
Anwendung: Lipase activity detection
350,00 €
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Streptozotocin
Streptozotocin

Artikelnummer: Cay13104-1

Streptozotocin (STZ) is a glucosamine-nitrosourea which is commonly used to induce experimental diabetes in animals. It specifically targets beta cells, entering via the glucose transporter GLUT2 and causing alkylation of DNA. DNA damage induces activation of poly ADP-ribosylation, depletion of cellular NAD+ and...
Schlagworte: Estreptozocin, NSC 37917, NSC 85998, STZ, U 9889, Zanosar, 2-deoxy-2-[[(methylnitrosoamino)carbonyl]amino]-D-glucose
Anwendung: Diabetes inducer, NO donor
CAS 18883-66-4
MW: 265.2 D
ab 32,00 €
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Arachidonic Acid (peroxide free)
Arachidonic Acid (peroxide free)

Artikelnummer: Cay90010.1-50

Free arachidonic acid is a transient, critical substrate for the biosynthesis of eicosanoid second messengers. Arachidonic acid oxidizes spontaneously on exposure to room air, yielding a complex mixture of fatty acid peroxides Peroxide-free arachidonic acid is obtained after removal of the peroxides by silicic acid...
Schlagworte: 5Z,8Z,11Z,14Z-eicosatetraenoic acid
Anwendung: Bioactive lipid assays
CAS 506-32-1
MW: 304.5 D
ab 37,00 €
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Leukotriene B4
Leukotriene B4

Artikelnummer: Cay20110-25

Leukotriene B4 (LTB4) is a dihydroxy fatty acid derived from arachidonic acid through the 5-LO pathway. It promotes a number of leukocyte functions including aggregation, stimulation of ion fluxes, enhancement of lysosomal enzyme release, superoxide anion production, chemotaxis, and chemokinesis. In subnanomolar...
Schlagworte: LTB4, 5S,12R-dihydroxy-6Z,8E,10E,14Z-eicosatetraenoic acid
Anwendung: Bioactive lipid assays
CAS 71160-24-2
MW: 336.5 D
ab 148,00 €
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1-Oleoyl-2-acetyl-sn-glycerol
1-Oleoyl-2-acetyl-sn-glycerol

Artikelnummer: Cay62600-10

OAG is a cell-permeable analog of the PKC-activating second messenger DAG. It activates PKC in platelets, resulting in the phosphorylation of a 40 kDa protein. OAG is metabolized to its corresponding phosphatidic acid (1-oleoyl-2-acetyl-3-phosphoglycerol), most likely through the action of a diglycerol kinase.
Schlagworte: OAG, 1-O-9Z-octadecenoyl-2-O-acetyl-sn-glycerol
Anwendung: Bioactive lipid assays
CAS 86390-77-4
MW: 398.6 D
ab 69,00 €
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Prostaglandin A1
Prostaglandin A1

Artikelnummer: Cay10010-50

Prostaglandin A1 (PGA1) was first isolated as a dehydration product of the PGE1 compounds found in human semen. It has been shown to cause renal vasodilation, increased urine sodium excretion, and lowered arterial pressure in hypertensive patients. It also has growth-inhibitory activity on tumor cells, the IC50...
Schlagworte: PGA1, 9-oxo-15S-hydroxy-prosta-10,13E-dien-1-oic acid
Anwendung: Bioactive lipid assays
CAS 14152-28-4
MW: 336.5 D
ab 35,00 €
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