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Produkte von Cayman Chemical

Cayman

Cayman Chemical Company ist ein Biotechunternehmen mit Sitz in Ann Arbor, Michigan, das mit seinen biochemischen Produkten Wissenschaftler weltweit bei der Arbeit in den Forschungsfeldern Krebs, NO Signalling, Neurologie, Apoptose, oxidativem Stress, Endokrinologie und vielen weiteren unterstützt. Cayman Chemical hat sich hierbei besonders auf die Herstellung von Assay-Kits zum Nachweis von Eicosanoiden, freien Radikalen, zyklischen Nukleotiden, Zytokinen, Hormonen und Stickstoffmonoxid spezialisiert. Neben diesen Kits bietet Cayman Chemical ein breites Angebot an Biochemikalien, darunter Eicosanoiden, NO Reagenzien sowie eine Reihe thematisch verwandter Lipide, Fettsäuren, Enzyme und Antikörper.

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Anhydrotetracycline (hydrochloride)
Anhydrotetracycline (hydrochloride)

Artikelnummer: Cay10009542-50

The tetracycline repressor (TetR) is a transcriptional regulator which normally binds tightly to its palindromic tetO operator DNA, blocking gene expression. Tet causes the repressor to dissociate from the DNA, allowing transcription to occur. A novel reverse TetR (revTetR) requires tetracycline as a co-repressor to...
Schlagworte: 4-(dimethylamino)-1,4S,4aS,5,12,12aS-hexahydro-3,10,11,12a-tetrahydroxy-6-methyl-1,12-dioxo-2-naphthacenecarboxamide,...
Anwendung: Antibiotic
CAS 13803-65-1
MW: 462.9 D
ab 45,00 €
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Prostaglandin D1
Prostaglandin D1

Artikelnummer: Cay12000-1

Prostaglandin D1 (PGD1) is the 1-series analog of PGD2 (Cay-12010). It is an inhibitor of ADP-induced platelet aggregation in humans with an IC50 value of 320 ng/ml, about 1/10 as potent as PGD2.
Schlagworte: PGD1, 9alpha,15S-dihydroxy-11-oxo-prost-13E-en-1-oic acid
Anwendung: Bioactive lipid assays
CAS 17968-82-0
MW: 354.5 D
ab 37,00 €
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-25 %
Einführungspreis
Estradiol ELISA Kit
Estradiol ELISA Kit

Artikelnummer: Cay501890-96

Estradiol is a steroid hormone produced from testosterone via the aromatase system in the granulosa cells of ovarian follicles. It is instrumental in the development of secondary sex characteristics at puberty and in the menstrual cycle. Plasma levels of estradiol peak during the follicular phase of the menstrual...
Schlagworte: 17beta-Estradiol, 17beta-Oestradiol, E2, Estradiol EIA Kit, beta-Estradiol
Anwendung: Competitive ELISA
250,00 € ab 187,50 €
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Vulpinic Acid
Vulpinic Acid

Artikelnummer: Cay21685-100

Vulpinic acid is a lichen metabolite that has been found in L. vulpina and has diverse biological activities. It is active against C. perfringens, B. vulgatus, B. fragilis, B. loescheii, P. acnes, E. faecium, and methicillin-susceptible and -resistant S. aureus (MICs = 4-16 µg/ml). Vulpinic acid (25-800 µM) prevents...
Schlagworte: NSC 5897, alphaE-(3-hydroxy-5-oxo-4-phenyl-2(5H)-furanylidene)-benzeneacetic acid, methyl ester
Anwendung: Bioactive lichen metabolite
CAS 521-52-8
MW: 322.3 D
ab 32,00 €
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Thymohydroquinone
Thymohydroquinone

Artikelnummer: Cay27558-10

Thymohydroquinone is a quinone that has been found in N. sativa seeds and has diverse biological activities. It scavenges 2,2-diphenyl-1-picrylhydrazyl (DPPH, Cay-14805) free radicals in a cell-free assay (IC50 = 2.4 µg/ml) and has a Trolox equivalent value of 2.6 in an oxygen radical absorbance capacity (ORAC)...
Schlagworte: NSC 34803, 2-methyl-5-(1-methylethyl)-1,4-benzenediol
Anwendung: Bioactive quinone
CAS 2217-60-9
MW: 166.2 D
ab 32,00 €
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Arachidic Acid-d2
Arachidic Acid-d2

Artikelnummer: Cay28083-5

Arachidic acid-d2 is intended for use as an internal standard for the quantification of arachidic acid (Cay-9000339, Cay-21906) by GC- or LC-MS. Arachidic acid is a long-chain saturated fatty acid that has been found in peanut butter and anaerobic fungi. It inhibits rabbit neutrophil aggregation induced by...
Schlagworte: Arachic Acid-d2, Eicosanoate-d2, Icosanoic Acid-d2, eicosanoic-2,2-d2 acid
Anwendung: GC-MS, LC-MS, Internal standard, Quantification, Saturated long-chain fatty acid
CAS 232600-70-3
MW: 314.5 D
ab 99,00 €
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SIN-1 (chloride)
SIN-1 (chloride)

Artikelnummer: Cay82220-50

As the active metabolite of molsidomine, SIN-1 (chloride) is a potent vasorelaxant and inhibitor of platelet aggregation. It produces both NO and superoxide and can therefore be used to generate peroxynitrite under physiological conditions.
Schlagworte: 3-Morpholino-sydnonimine, Linsidomine, 5-amino-3-(4-morpholinyl)-1,2,3-oxadiazolium chloride
Anwendung: Peroxynitrite generation
CAS 16142-27-1
MW: 206.6 D
ab 18,00 €
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Tetrahydrouridine
Tetrahydrouridine

Artikelnummer: Cay16402-10

Tetrahydrouridine is a competitive, reversible inhibitor of cytidine deaminase (Ki values = 54 and 240 nM for human and E. coli enzymes, respectively). Its use, alone or in combination with the DNA methyltransferase inhibitor 5-fluoro-2'-deoxycytidine, is being evaluated in animal models and clinical trials for...
Schlagworte: NSC 112907, THU, 3,4,5,6-tetrahydro-uridine
Anwendung: Competitive, reversible cytidine deaminase inhibitor
CAS 18771-50-1
MW: 248.2 D
ab 32,00 €
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Lignoceric Acid-d4
Lignoceric Acid-d4

Artikelnummer: Cay28024-1

Lignoceric Acid-d4 is intended for use as an internal standard for the quantification of lignoceric acid (Cay-13353) by GC- or LC-MS. Lignoceric acid is a 24-carbon saturated (24:0) fatty acid. In mammals, it is synthesized during brain development and is found in cerebrosides. The deficient peroxisomal oxidation of...
Schlagworte: tetracosanoic-3,3,5,5-d4 acid
Anwendung: GC-MS, LC-MS, Internal standard, Quantification, Saturated very-long-chain fatty acid
CAS 61389-26-2
MW: 372.7 D
ab 62,00 €
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2-Deoxyuridine
2-Deoxyuridine

Artikelnummer: Cay27803-1

2-Deoxyuridine is a pyrimidine nucleoside composed of the pyrimidine base uracil attached to the sugar deoxyribose. It has been used as a precursor in the synthesis of antiviral deoxyuridine derivatives, including idoxuridine (Cay-20222). Formulations containing 2-deoxyuridine have been used in the deoxyuridine...
Schlagworte: NSC 23615, Uracil Deoxyriboside, 2'-deoxy-uridine
Anwendung: Pyrimidine nucleoside
CAS 951-78-0
MW: 228.2 D
ab 37,00 €
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Bacopasaponin C
Bacopasaponin C

Artikelnummer: Cay11820-5

Bacopasaponin C is a triterpenoid saponin originally isolated from B. monniera that has diverse biological activities. It inhibits the ATPase activity of P-glycoprotein (IC50 = 57.83 µg/ml). Bacopasaponin C inhibits scopolamine-induced impairments in spatial memory in the Morris water maze and memory retrieval in...
Schlagworte: (-)-Bacopasaponin C,...
Anwendung: Bioactive triterpenoid saponin
CAS 178064-13-6
MW: 8991 D
ab 94,00 €
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Bacopaside II
Bacopaside II

Artikelnummer: Cay11822-5

Bacopaside II is a triterpene glycoside found in B. monnieri that has neuroprotective, anti-angiogenic, and anticancer activities. Bacopaside II (0.4 mg/ml) decreases hydrogen peroxide-induced intracellular reactive oxygen species (ROS) production and cell death in N2a neuroblastoma cells. It decreases immobility...
Schlagworte: (1S,2R,4aR,6aS,6bR,8aR,10S,12aR,12bR,14aR,14bS)-hexadecahydro-1-hydroxy-1,6b,9,9,12a-pentamethyl-2-(2-methyl-1-propen-1-yl...
Anwendung: Neuroprotective, antiangiogenic, anticancer triterpene glycoside
CAS 382146-66-9
MW: 9291 D
ab 107,00 €
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