Produkte von Cayman Chemical

Cayman

Cayman Chemical Company ist ein Biotechunternehmen mit Sitz in Ann Arbor, Michigan, das mit seinen biochemischen Produkten Wissenschaftler weltweit bei der Arbeit in den Forschungsfeldern Krebs, NO Signalling, Neurologie, Apoptose, oxidativem Stress, Endokrinologie und vielen weiteren unterstützt. Cayman Chemical hat sich hierbei besonders auf die Herstellung von Assay-Kits zum Nachweis von Eicosanoiden, freien Radikalen, zyklischen Nukleotiden, Zytokinen, Hormonen und Stickstoffmonoxid spezialisiert. Neben diesen Kits bietet Cayman Chemical ein breites Angebot an Biochemikalien, darunter Eicosanoiden, NO Reagenzien sowie eine Reihe thematisch verwandter Lipide, Fettsäuren, Enzyme und Antikörper.

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Uric Acid (sodium salt)
Uric Acid (sodium salt)

Artikelnummer: Cay16219-2

Uric acid is a ubiquitous end product of purine metabolism in humans that is mainly excreted in urine, whereas in other mammals it is further metabolized to allantoin by uricase. The final two steps in its production are catalyzed by xanthine oxidase, which generates superoxide. Uric acid acts as a potent...
Schlagworte: 7,9-dihydro-1H-purine-2,6,8(3H)-trione, monosodium salt
Anwendung: Antioxidant, Disease causing agent
CAS 1198-77-2
MW: 190.1 D
87,00 €
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Human Fibrinogen (PAD4 Citrullinated)
Human Fibrinogen (PAD4 Citrullinated)

Artikelnummer: Cay400076-1

Fibrinogen is a plasma clotting factor composed of three different polypeptide chains (alpha, beta and gamma). Under chronic inflammatory conditions, fibrinogen can be acted upon by the enzyme peptidylarginine deiminase 4 (PAD4), converting specific arginine residues to citrulline. Patients with rheumatoid arthritis...
Schlagworte: cFBG, FGA, Fibrinopeptide A, Fibrinogen alpha chain, FGB, Fibrinopeptide B, Fibrinogen beta chain, FGG, PRO2061,...
Anwendung: WB
407,00 €
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Cyclic AMP ELISA Kit
Cyclic AMP ELISA Kit

Artikelnummer: Cay581001-96

Cayman's cAMP assay is a very sensitive competitive ELISA that permits cAMP measurements within the standard curve range of 0.078-10 pmol/ml, typically with a sensitivity (80% B/B0) of 0.1 pmol/ml once samples and standards have been acetylated prior to analysis. This assay has been validated with culture media,...
Schlagworte: Adenosine 3',5'-cyclic mononucleotide, Adenosine 3',5'-cyclic monophosphate, cAMP EIA Kit
Anwendung: ELISA
ab 338,00 €
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Testosterone ELISA Kit
Testosterone ELISA Kit

Artikelnummer: Cay582701-96

Testosterone is the prototypic and predominant circulating androgenic steroid. It plays a major role in the growth and function of many reproductive and non-reproductive tissues and organs including muscle, liver, and brain, directing the development of the male phenotype during embryogenesis and at puberty....
Schlagworte: Testosterone EIA Kit
Anwendung: ELISA
ab 288,00 €
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TNF-alpha (human) ELISA Kit
TNF-alpha (human) ELISA Kit

Artikelnummer: Cay589201-96

Tumor Necrosis Factor-alpha (TNF-alpha) is a 17 kDa polypeptide produced primarily by activated monocytes and macrophages. This polypeptide mediates many immune and inflammatory responses, including activation and differentiation of monocytes and macrophages, expression of MHC class I and II, and expression of...
Schlagworte: TNF, TNFA, TNF-a, Cachectin, TNF-alpha, Tumor necrosis factor, Tumor necrosis factor ligand superfamily member 2
Anwendung: ELISA
Reaktivität: Human
ab 454,00 €
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Antioxidant Assay Kit
Antioxidant Assay Kit

Artikelnummer: Cay709001-96

The antioxidant system of living organisms includes enzymes such as superoxide dismutase, catalase, and glutathione peroxidase, macromolecules such as albumin, ceruloplasmin, and ferritin, and an array of small molecules, including ascorbic acid, alpha-tocopherol, beta-carotene, reduced glutathione, uric acid, and...
Anwendung: Antioxidant capacity determination
288,00 €
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Prostaglandin E2-d9
Prostaglandin E2-d9

Artikelnummer: Cay10581-250

PGE2-d9 contains nine deuterium atoms at the 17, 17', 18, 18', 19, 19', 20, 20, and 20' positions. It is intended for use as an internal standard for the quantification of PGE2 by GC- or LC-mass spectrometry (MS). PGE2 is one of the primary cyclooxygenase products of arachidonic acid and one of the most widely...
Schlagworte: Dinoprostone-d9, PGE2-d9, 9-oxo-11alpha,15S-dihydroxy-prosta-5Z,13E-dien-1-oic-17,17,18,18,19,19,20,20,20-d9 acid
Anwendung: Standard
CAS 1356347-42-6
MW: 361.5 D
ab 64,00 €
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BAPTA
BAPTA

Artikelnummer: Cay11706-100

BAPTA is a membrane-impermeable calcium chelator that binds extracellular calcium ions. The presence of four carboxylic acid functional groups allows for the binding of two calcium ions. BAPTA and its derivatives are widely used for the measurement and manipulation of intracellular free calcium concentration.
Schlagworte: N,N'-[1,2-ethanediylbis(oxy-2,1-phenylene)]bis[N-(carboxymethyl)-glycine
Anwendung: Calcium chelator
CAS 85233-19-8
MW: 476.4 D
ab 32,00 €
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Oleoyl Serinol
Oleoyl Serinol

Artikelnummer: Cay13637-100

Oleoyl serinol is an analog of ceramide and an agonist of the cannabinoid receptor GPR119 that has an EC50 value of 12 µM for stimulating secretion of GLP-1 in mouse endocrine GLUTag cells. It has been found in E. coli that express human microbiota N-acyl synthase (hmNAS) genes. It induces cell death of F-11 murine...
Schlagworte: N-Oleoyl Serinol, S-18, N-[2-hydroxy-1-(hydroxymethyl)ethyl]-9Z-octadecenamide
Anwendung: GPR119 agonist
CAS 72809-08-6
MW: 355.6 D
ab 42,00 €
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Malonyl Coenzyme A (lithium salt)
Malonyl Coenzyme A (lithium salt)

Artikelnummer: Cay16455-10

Malonyl coenzyme A is a coenzyme A (CoA, Cay-16147) derivative that is used in fatty acid and polyketide synthesis and in the transport of alpha-ketoglutarate across the mitochondrial membrane. Malonyl-CoA is formed by acetyl-CoA carboxylase-mediated carboxylation of acetyl-CoA (Cay-16160). Fatty acid synthase...
Schlagworte: Malonyl-CoA, S-(hydrogen propanedioate) coenzyme A, lithium salt
Anwendung: Fatty acid & polyketide synthesis intermediate
CAS 108347-84-8
MW: 860.5 D
ab 44,00 €
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n-Dodecyl-beta-D-maltoside
n-Dodecyl-beta-D-maltoside

Artikelnummer: Cay16494-5

n-Dodecyl-beta-D-maltoside (DDM) is a non-ionic detergent commonly used to solubilize membrane-associated proteins. In particular, it helps retain the native conformation and activity of membrane-associated proteins, and facilitates the reforming of these proteins after denaturation. The critical micelle...
Schlagworte: DDM, Dodecyl Maltoside, dodecyl 4-O-alpha-D-glucopyranosyl-beta-D-glucopyranoside
Anwendung: Non-ionic detergent
CAS 69227-93-6
MW: 510.6 D
ab 62,00 €
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15-deoxy-Delta12,14-Prostaglandin J2
15-deoxy-Delta12,14-Prostaglandin J2

Artikelnummer: Cay18570-1

15-deoxy-Delta12,14-Prostaglandin J2 (15-deoxy-Delta12,14-PGJ2) is formed from PGD2 by the elimination of two molecules of water. It binds selectively to PPARgamma with an EC50 value of 2 µM in a murine chimera system. 15-deoxy-Delta12,14-PGJ2 is more potent than PGD2, Delta12-PGJ2, and PGJ2 in stimulating...
Schlagworte: 15-deoxy-Delta12,14-PGJ2, 11-oxo-prosta-5Z,9,12E,14E-tetraen-1-oic acid
Anwendung: Bioactive lipid assays
CAS 87893-55-8
MW: 316,4 D
ab 32,00 €
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