Produkte von Cayman Chemical

Cayman

Cayman Chemical Company ist ein Biotechunternehmen mit Sitz in Ann Arbor, Michigan, das mit seinen biochemischen Produkten Wissenschaftler weltweit bei der Arbeit in den Forschungsfeldern Krebs, NO Signalling, Neurologie, Apoptose, oxidativem Stress, Endokrinologie und vielen weiteren unterstützt. Cayman Chemical hat sich hierbei besonders auf die Herstellung von Assay-Kits zum Nachweis von Eicosanoiden, freien Radikalen, zyklischen Nukleotiden, Zytokinen, Hormonen und Stickstoffmonoxid spezialisiert. Neben diesen Kits bietet Cayman Chemical ein breites Angebot an Biochemikalien, darunter Eicosanoiden, NO Reagenzien sowie eine Reihe thematisch verwandter Lipide, Fettsäuren, Enzyme und Antikörper.

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Short-Chain Fatty Acid LC-MS Mixture
Short-Chain Fatty Acid LC-MS Mixture

Artikelnummer: Cay18824-1

This mixture contains various short-chain fatty acids (?12:0). The mixture is supplied in an amber ampule in which the headspace has been purged with argon to prevent lipid oxidation. This product has been designed for direct use in LC-MS applications. The solution may be serially diluted for preparation of...
Schlagworte: Contains various short-chain fatty acids (?12:0)
Anwendung: LC-MS, Calibrator / standard preparation
62,00 €
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5-Phospho-D-ribose 1-diphosphate (sodium salt)
5-Phospho-D-ribose 1-diphosphate (sodium salt)

Artikelnummer: Cay18897-10

5-Phospho-D-ribose 1-diphosphate (PRPP) is a natural intermediate involved in the pentose phosphate pathway leading to purine, pyrimidine, and histidine metabolism. It is also an intermediate in the synthesis of plant hormones, alkaloids, and other secondary metabolites from glucose. Several...
Schlagworte: Phosphoribosyl Pyrophosphate, P-rib-PP, PRPP, 5-(dihydrogen phosphate) 1-(trihydrogen diphosphate) alpha-D-ribofuranose,...
Anwendung: Pentose phosphate pathway intermediate, APRT substrate
CAS 108321-05-7
MW: 500 D
ab 32,00 €
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Odd-Chain Fatty Acid LC-MS Mixture
Odd-Chain Fatty Acid LC-MS Mixture

Artikelnummer: Cay19227-1

This mixture contains various odd-chain fatty acids (C11:0-C19:1). The mixture is supplied in an amber ampule in which the headspace has been purged with argon to prevent lipid oxidation. This product has been designed for direct use in LC-MS applications. The solution may be serially diluted for preparation of...
Anwendung: LC-MS
62,00 €
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Citrullinated Histone H3 (Clone 11D3) ELISA Kit
Citrullinated Histone H3 (Clone 11D3) ELISA Kit

Artikelnummer: Cay501620-96

Histone H3 is citrullinated by peptidylarginine deiminase 4 (PAD4) at residues R2, R8, and R17 during the processes of epigenetic chromatin remodeling and neutrophil extracellular trap (NET) formation. In vitro, citrullinated H3 (CitH3) is released from neutrophils that have been stimulated with calcium ionophore...
Schlagworte: CitH3 (Clone 11D3) EIA Kit
Anwendung: ELISA
619,00 €
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Prostaglandin E2 ELISA Kit - Monoclonal
Prostaglandin E2 ELISA Kit - Monoclonal

Artikelnummer: Cay514010-96

Prostaglandin E2 (PGE2) is a primary product of arachidonic acid metabolism in many cells. Like most eicosanoids, it does not exist preformed in any cellular reservoir. When cells are activated or exogenous free arachidonate is supplied, PGE2 is synthesized de novo and released into the extracellular space. In vivo,...
Schlagworte: PGE2 EIA Kit - Monoclonal
Anwendung: ELISA
ab 344,00 €
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DNA/RNA Oxidative Damage ELISA Kit
DNA/RNA Oxidative Damage ELISA Kit

Artikelnummer: Cay589320-96

DNA and RNA are damaged by oxidation during aging and in a variety of disease states including cancer. Guanine is the base is most prone to oxidation, and the repair processes initiated to correct the damage release multiple oxidized guanine species into the urine, including 8-hydroxyguanosine (8-OHG),...
Schlagworte: 8-hydroxy-2'-Deoxyguanosine, 8-OH-2dG, 8-OH-DG, DNA/RNA Oxidative Damage ELISA Kit
Anwendung: ELISA
ab 719,00 €
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Pyruvate Assay Kit
Pyruvate Assay Kit

Artikelnummer: Cay700470-96

Pyruvate (pyruvic acid) is a key intermediate in cellular metabolic pathways and is derived primarily from glucose via glycolysis. Abnormal blood pyruvate levels are reported in a number of disorders including shock, liver disease, congestive heart failure, diabetes mellitus, thiamine deficiency, and metabolic...
Schlagworte: Pyruvic Acid Assay Kit
Anwendung: Pyruvate quantification
318,00 €
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Prostaglandin E2-d9
Prostaglandin E2-d9

Artikelnummer: Cay10581-50

PGE2-d9 contains nine deuterium atoms at the 17, 17', 18, 18', 19, 19', 20, 20, and 20' positions. It is intended for use as an internal standard for the quantification of PGE2 by GC- or LC-mass spectrometry (MS). PGE2 is one of the primary cyclooxygenase products of arachidonic acid and one of the most widely...
Schlagworte: Dinoprostone-d9, PGE2-d9, 9-oxo-11alpha,15S-dihydroxy-prosta-5Z,13E-dien-1-oic-17,17,18,18,19,19,20,20,20-d9 acid
Anwendung: Standard
CAS 1356347-42-6
MW: 361.5 D
ab 64,00 €
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BAPTA
BAPTA

Artikelnummer: Cay11706-100

BAPTA is a membrane-impermeable calcium chelator that binds extracellular calcium ions. The presence of four carboxylic acid functional groups allows for the binding of two calcium ions. BAPTA and its derivatives are widely used for the measurement and manipulation of intracellular free calcium concentration.
Schlagworte: N,N'-[1,2-ethanediylbis(oxy-2,1-phenylene)]bis[N-(carboxymethyl)-glycine
Anwendung: Calcium chelator
CAS 85233-19-8
MW: 476.4 D
ab 32,00 €
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Oleoyl Serinol
Oleoyl Serinol

Artikelnummer: Cay13637-100

Oleoyl serinol is an analog of ceramide and an agonist of the cannabinoid receptor GPR119 that has an EC50 value of 12 µM for stimulating secretion of GLP-1 in mouse endocrine GLUTag cells. It has been found in E. coli that express human microbiota N-acyl synthase (hmNAS) genes. It induces cell death of F-11 murine...
Schlagworte: N-Oleoyl Serinol, S-18, N-[2-hydroxy-1-(hydroxymethyl)ethyl]-9Z-octadecenamide
Anwendung: GPR119 agonist
CAS 72809-08-6
MW: 355.6 D
ab 42,00 €
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Epibrassinolide
Epibrassinolide

Artikelnummer: Cay20337-1

Epibrassinolide is a brassinosteroid that can be isolated from various plants and has been shown to decrease toxicity and stimulate healthy plant growth in plants under stress. Epibrassinolide is also reported to be a potential apoptotic inducer in various cancer cells without affecting the non-tumor cell growth. It...
Schlagworte: 24-Epibrassinolide, EBL,...
Anwendung: Brassinosteroid, Apoptotic inducer
CAS 78821-43-9
MW: 480.7 D
ab 69,00 €
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Acetoacetyl Coenzyme A (sodium salt hydrate)
Acetoacetyl Coenzyme A (sodium salt hydrate)

Artikelnummer: Cay21219-10

Acetoacetyl coenzyme A (acetoacetyl-CoA) is a precursor to HMG-CoA in the isoprenoid pathway. It is reversibly converted to acetyl-CoA by acetoacetyl-CoA thiolase in the mitochondria. Acetoacetyl-CoA thiolase (T2) deficiency results in a build-up of ketone bodies leading to intermittent ketoacidosis. Acetoacetyl-CoA...
Schlagworte: Acetoacetyl-CoA, S-(3-oxobutanoate) coenzyme A, trisodium salt, tetrahydrate
Anwendung: HMG-CoA precursor
MW: 989.6 D
ab 38,00 €
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