Produkte von Cayman Chemical

Cayman

Cayman Chemical Company ist ein Biotechunternehmen mit Sitz in Ann Arbor, Michigan, das mit seinen biochemischen Produkten Wissenschaftler weltweit bei der Arbeit in den Forschungsfeldern Krebs, NO Signalling, Neurologie, Apoptose, oxidativem Stress, Endokrinologie und vielen weiteren unterstützt. Cayman Chemical hat sich hierbei besonders auf die Herstellung von Assay-Kits zum Nachweis von Eicosanoiden, freien Radikalen, zyklischen Nukleotiden, Zytokinen, Hormonen und Stickstoffmonoxid spezialisiert. Neben diesen Kits bietet Cayman Chemical ein breites Angebot an Biochemikalien, darunter Eicosanoiden, NO Reagenzien sowie eine Reihe thematisch verwandter Lipide, Fettsäuren, Enzyme und Antikörper.

Mehr unter: www.caymanchem.com

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Imipenem (hydrate)
Imipenem (hydrate)

Artikelnummer: Cay16039-100

Imipenem is an intravenous beta-lactam antibiotic effective against a wide range of Gram-positive and Gram-negative bacteria (MICs range from 0.5-2 µg/ml for E. cloacae and P. aeruginosa), including several multi-drug resistant bacterial species. Imipenem acts by interfering with bacterial cell wall synthesis.
Schlagworte: N-Formimidoyl Thienamycin,...
Anwendung: Antibacterial antibiotic, Peptidoglycan biosynthesis inhibitor
CAS 74431-23-5
MW: 317.4 D
ab 57,00 €
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Oxygen Consumption Rate Assay Kit (MitoXpress(R) Xtra HS Method)
Oxygen Consumption Rate Assay Kit (MitoXpress(R) Xtra HS...

Artikelnummer: Cay600800-96

The oxygen consumption rate (OCR) of cells is an important indicator of normal cellular function. It is used as a parameter to study mitochondrial function as well as a marker of factors triggering the switch from healthy oxidative phosphorylation to aerobic glycolysis in cancer cells. Oxygen consumption is...
Anwendung: Fluorescence
437,00 €
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nor-NOHA (acetate)
nor-NOHA (acetate)

Artikelnummer: Cay10006861-1

L-Arginine serves as a common substrate for both nitric oxide synthase (NOS) and arginase in the cell. NOS catalyzes the oxidation of arginine to citrulline and NO with Nomega-hydroxy-L-arginine (NOHA) formed as an intermediate. Arginase, on the other hand, catalyzes the hydrolysis of arginine into urea and...
Schlagworte: Nomega-hydroxy-nor-Arginine, 2S-amino-4-[[(hydroxyamino)iminomethyl]amino]-butanoic acid, diacetate
Anwendung: Arginase inhibitor
CAS 1140844-63-8
MW: 296.3 D
ab 22,00 €
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Puromycin (hydrochloride)
Puromycin (hydrochloride)

Artikelnummer: Cay13884-25

Puromycin is an aminonucleoside antibiotic, derived from S. alboniger, that blocks protein synthesis in both prokaryotes and eukaryotes by causing premature termination of nascent polypeptide chains. A portion of the puromycin molecule resembles the 3' end of aminoacylated tRNA. It enters the A site of the ribosome...
Schlagworte: CL 13,900, CL 16,536, NSC 3055, PDH, 3'-[[2S-amino-3-(4-methoxyphenyl)-1-oxopropyl]amino]-3'-deoxy-N,N-dimethyl-adenosine,...
Anwendung: Aminonucleosid antibiotic
CAS 58-58-2
MW: 544.4 D
ab 37,00 €
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Acetoacetyl Coenzyme A (sodium salt hydrate)
Acetoacetyl Coenzyme A (sodium salt hydrate)

Artikelnummer: Cay21219-5

Acetoacetyl coenzyme A (acetoacetyl-CoA) is a precursor to HMG-CoA in the isoprenoid pathway. It is reversibly converted to acetyl-CoA by acetoacetyl-CoA thiolase in the mitochondria. Acetoacetyl-CoA thiolase (T2) deficiency results in a build-up of ketone bodies leading to intermittent ketoacidosis. Acetoacetyl-CoA...
Schlagworte: Acetoacetyl-CoA, S-(3-oxobutanoate) coenzyme A, trisodium salt, tetrahydrate
Anwendung: HMG-CoA precursor
MW: 989.6 D
ab 82,00 €
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Fumonisin B1
Fumonisin B1

Artikelnummer: Cay62580-5

Fumonisin B1 is a mycotoxin produced from F. moniliforme, a prevalent fungus of corn and other grains. Outbreaks of food poisoning in livestock and humans following the consumption of Fusarium infested corn are caused by fumonisins. It functions as an inhibitor of ceramide synthase (sphingosine N-acyltransferase)....
Schlagworte: FB1, (2R,2'R)-1,2,3-propanetricarboxylic acid,...
Anwendung: Ceramide synthase inhibitor
CAS 116355-83-0
MW: 721.8 D
ab 74,00 €
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Palmitic Acid
Palmitic Acid

Artikelnummer: Cay10006627-10

Saturated fatty acids are synthesized by both plants and animals from acetyl coenzyme A as a form of long-term energy storage. Palmitic acid is a common 16-carbon saturated fat that represents 10-20% of the normal human dietary fat intake. Palmitic acid also makes up approximately 25% of the total plasma fatty acids...
Schlagworte: hexadecanoic acid
Anwendung: Bioactive lipid assays
CAS 57-10-3
MW: 256.4 D
ab 32,00 €
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Prostaglandin A1
Prostaglandin A1

Artikelnummer: Cay10010-50

Prostaglandin A1 (PGA1) was first isolated as a dehydration product of the PGE1 compounds found in human semen. It has been shown to cause renal vasodilation, increased urine sodium excretion, and lowered arterial pressure in hypertensive patients. It also has growth-inhibitory activity on tumor cells, the IC50...
Schlagworte: PGA1, 9-oxo-15S-hydroxy-prosta-10,13E-dien-1-oic acid
Anwendung: Bioactive lipid assays
CAS 14152-28-4
MW: 336.5 D
ab 35,00 €
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(+)-Abscisic Acid
(+)-Abscisic Acid

Artikelnummer: Cay10073-1

Abscisic acid (ABA) is a plant hormone with diverse roles in disease resistance, plant development, and response to stresses (water, salt, temperature, and pathogens). It is also produced by some plant pathogenic fungi. In addition to key roles in regulating stomatal closing, seed dormancy, and cell division, ABA...
Schlagworte: (+)-ABA, Dormin, 5-[(1S)-1-hydroxy-2,6,6-trimethyl-4-oxo-2-cyclohexen-1-yl]-3-methyl-2Z,4E-pentadienoic acid
Anwendung: Plant hormone
CAS 21293-29-8
MW: 264.3 D
ab 20,00 €
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Oligomycin A
Oligomycin A

Artikelnummer: Cay11342-1

Oligomycins are macrolides created by Streptomyces species that can be toxic to other organisms. Different oligomycin isomers are highly specific for the disruption of mitochondrial metabolism. Oligomycin A, a dominant analog of the isomers, is an inhibitor of mitochondrial F1FO ATP synthase that induces apoptosis...
Schlagworte: MCH 32,...
Anwendung: Apoptosis inducer
CAS 579-13-5
MW: 791.1 D
ab 55,00 €
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Disuccinimidyl Suberate
Disuccinimidyl Suberate

Artikelnummer: Cay13008-50

Disuccinimidyl suberate (DSS) is a bifunctional cross-linking reagent which contains two N-hydroxysuccinimide esters that are reactive toward primary amines. DSS is membrane-permeable and is commonly used to cross-link proteins in intact cells.
Schlagworte: DSS, NSC 340008, octanedioic acid, 1,8-bis(2,5-dioxo-1-pyrrolidinyl)ester
Anwendung: Cross-linking reagent
CAS 68528-80-3
MW: 368.3 D
ab 9,00 €
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2-Arachidonoyl Glycerol
2-Arachidonoyl Glycerol

Artikelnummer: Cay62160-25

2-Arachidonoyl glycerol (2-AG) is an endogenous agonist of the cannabinoid (CB) receptors CB1 and CB2 (Kis = 25.3-472 and 145-1,400 nM, respectively). Unlike arachidonoyl ethanolamide (AEA, Cay-90050), 2-AG is present at relatively high levels in the central nervous system and is the most abundant molecular species...
Schlagworte: 2-AG, 5Z,8Z,11Z,14Z-eicosatetraenoic acid, 2-glyceryl ester
Anwendung: CB1 receptor agonist
CAS 53847-30-6
MW: 378.6 D
ab 32,00 €
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