Produkte von Cayman Chemical

Cayman

Cayman Chemical Company ist ein Biotechunternehmen mit Sitz in Ann Arbor, Michigan, das mit seinen biochemischen Produkten Wissenschaftler weltweit bei der Arbeit in den Forschungsfeldern Krebs, NO Signalling, Neurologie, Apoptose, oxidativem Stress, Endokrinologie und vielen weiteren unterstützt. Cayman Chemical hat sich hierbei besonders auf die Herstellung von Assay-Kits zum Nachweis von Eicosanoiden, freien Radikalen, zyklischen Nukleotiden, Zytokinen, Hormonen und Stickstoffmonoxid spezialisiert. Neben diesen Kits bietet Cayman Chemical ein breites Angebot an Biochemikalien, darunter Eicosanoiden, NO Reagenzien sowie eine Reihe thematisch verwandter Lipide, Fettsäuren, Enzyme und Antikörper.

Mehr unter: www.caymanchem.com

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Ionomycin (calcium salt)
Ionomycin (calcium salt)

Artikelnummer: Cay11932-1

Ionomycin is a selective calcium ionophore derived from S. conglobatus that mobilizes intracellular calcium stores. It is used as a research tool to raise the intracellular level of calcium, to study calcium transport across biological membranes, and to stimulate the intracellular production of cytokines. This...
Schlagworte: 11,19R,21S-trihydroxy-4R,6S,8S,12R,14R,18R,20S-heptamethyl-22-[octahydro-5'S-[1R-hydroxyethyl]-2S,5'-dimethyl[2,2'R-bifura...
Anwendung: Calcium ionophore
CAS 56092-82-1
MW: 747.1 D
ab 32,00 €
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Arachidonic Acid-d11
Arachidonic Acid-d11

Artikelnummer: Cay10006758-100

Arachidonic acid-d11 contains 11 deuterium atoms at the 16, 16, 17, 17, 18, 18, 19, 19, 20, 20, and 20 positions. It is intended for use as an internal standard for the quantification of arachidonic acid (Cay-90010) by GC- or LC-mass spectrometry. Arachidonic acid is an essential fatty acid and a precursor for all...
Schlagworte: AA-d11, 5Z,8Z,11Z,14Z-eicosatetraenoic-16,16,17,17,18,18,19,19,20,20,20-d11 acid
Anwendung: GC-MS, LC-MS, Internal standard
MW: 315.5 D
ab 48,00 €
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Imipenem (hydrate)
Imipenem (hydrate)

Artikelnummer: Cay16039-100

Imipenem is an intravenous beta-lactam antibiotic effective against a wide range of Gram-positive and Gram-negative bacteria (MICs range from 0.5-2 µg/ml for E. cloacae and P. aeruginosa), including several multi-drug resistant bacterial species. Imipenem acts by interfering with bacterial cell wall synthesis.
Schlagworte: N-Formimidoyl Thienamycin,...
Anwendung: Antibacterial antibiotic, Peptidoglycan biosynthesis inhibitor
CAS 74431-23-5
MW: 317.4 D
ab 57,00 €
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Prostaglandin E2 ELISA Kit - Monoclonal
Prostaglandin E2 ELISA Kit - Monoclonal

Artikelnummer: Cay514010-96S

Prostaglandin E2 (PGE2) is a primary product of arachidonic acid metabolism in many cells. Like most eicosanoids, it does not exist preformed in any cellular reservoir. When cells are activated or exogenous free arachidonate is supplied, PGE2 is synthesized de novo and released into the extracellular space. In vivo,...
Schlagworte: PGE2 EIA Kit - Monoclonal
Anwendung: ELISA
ab 344,00 €
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DNA/RNA Oxidative Damage ELISA Kit
DNA/RNA Oxidative Damage ELISA Kit

Artikelnummer: Cay589320-96

DNA and RNA are damaged by oxidation during aging and in a variety of disease states including cancer. Guanine is the base is most prone to oxidation, and the repair processes initiated to correct the damage release multiple oxidized guanine species into the urine, including 8-hydroxyguanosine (8-OHG),...
Schlagworte: 8-hydroxy-2'-Deoxyguanosine, 8-OH-2dG, 8-OH-DG, DNA/RNA Oxidative Damage ELISA Kit
Anwendung: ELISA
ab 619,00 €
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Glutathione Peroxidase Assay Kit
Glutathione Peroxidase Assay Kit

Artikelnummer: Cay703102-96

Glutathione peroxidase (GPX) catalyzes the reduction of hydroperoxides, including hydrogen peroxides, by reduced glutathione and functions to protect the cell from oxidative damage. With the exception of phospholipid-hydroperoxide GPX, a monomer, all of the GPX enzymes are tetramers of four identical subunits. Each...
Schlagworte: EC=1.11.1.9, GPX
Anwendung: GTx activity detection
ab 357,00 €
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Superoxide Dismutase Assay Kit
Superoxide Dismutase Assay Kit

Artikelnummer: Cay706002-96

Significant amounts of superoxide dismutase (SOD) in cellular and extracellular environments are crucial for the prevention of diseases linked to oxidative stress. Mutations in SOD account for approximately 20% of familial amyotrophic lateral sclerosis (ALS) cases. SOD also appears to be important in the prevention...
Schlagworte: SOD
Anwendung: SOD detection
ab 282,00 €
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Catalase Assay Kit
Catalase Assay Kit

Artikelnummer: Cay707002-96

Catalase (EC 1.11.1.6, 2H2O2 oxidoreductase) is an ubiquitous antioxidant enzyme that is present in most aerobic cells. Catalase (CAT) is involved in the detoxification of hydrogen peroxide (H2O2), a reactive oxygen species (ROS), which is a toxic product of both normal aerobic metabolism and pathogenic ROS...
Schlagworte: CAT, Catalase, EC=1.11.1.6
Anwendung: Catalase activity determination
ab 338,00 €
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Nitrate/Nitrite Colorimetric Assay Kit
Nitrate/Nitrite Colorimetric Assay Kit

Artikelnummer: Cay780001-192

The Cayman Chemical Nitrate/Nitrite Assay Kit provides an accurate and convenient method for measurement of total nitrate/nitrite concentration in a simple two-step process. The first step is the conversion of nitrate to nitrite utilizing nitrate reductase. The second step is the addition of the Griess Reagents...
Anwendung: Nitrate detection, Nitrite detection
232,00 €
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Eicosapentaenoic Acid
Eicosapentaenoic Acid

Artikelnummer: Cay90110-50

EPA is an omega-3 fatty acid abundantly available in marine organisms. It is oxygenated by COX-1 and COX-2 at rates of about 5% and 30%, respectively, compared to arachidonic acid. EPA has been shown to offer protection against coronary heart disease, thrombosis, ischemic brain injury, scaly dermatitis, and some...
Schlagworte: EPA, Timnodonic Acid, 5Z,8Z,11Z,14Z,17Z-eicosapentaenoic acid
Anwendung: Bioactive lipid assays
CAS 10417-94-4
MW: 302.5 D
ab 37,00 €
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Docosahexaenoic Acid
Docosahexaenoic Acid

Artikelnummer: Cay90310-50

DHA is an essential fatty acid and the most abundant omega-3 fatty acid in neural tissues, especially in the retina and brain. DHA constitutes as much as 40% of the total PUFA pool in retinal and neuronal membranes. Supplementation of dietary DHA using fish oil inhibits the progression of atherosclerosis and delays...
Schlagworte: Cervonic Acid, DHA, 4Z,7Z,10Z,13Z,16Z,19Z-docosahexaenoic acid
Anwendung: Bioactive lipid studies
CAS 6217-54-5
MW: 328.5 D
ab 33,00 €
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Sphingosine-1-phosphate
Sphingosine-1-phosphate

Artikelnummer: Cay62570-1

Sphingosine-1-phosphate (S1P) is the product of phosphorylation of sphingosine by sphingosine kinase. Like many products of sphingomyelin, it exhibits a wide range of biological activities. Not only does it enhance cell growth, but it can inhibit the normal apoptotic response to a variety of stimuli. The ability of...
Schlagworte: S1P, Sphingosine-1-Phosphoric Acid, 2S-amino-4E-octadecene-1,3R-diol 1-(dihydrogen phosphate)
Anwendung: Bioactive lipid assays
CAS 26993-30-6
MW: 379.5 D
ab 119,00 €
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