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Item number: ABD-13401
A fluorogenic substrate for caspase 3. The 7-amido-4-trifluoromethylcoumarin derivatives have better membrane permeability than the 7-amido-4-methylcoumarin derivatives.
Application: | Caspase-3 substrate |
CAS | 201608-14-2 |
139.00€
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Item number: ABD-13430
Cleavage of R110 peptides by caspases generates strongly fluorescent R110 that can be monitored fluorimetrically at 510-530 nm with excitation of 488 nm.This R110 substrate is specific for caspases 3 and 7.
Application: | Caspase-3 substrate, Caspase-7 substrate |
139.00€
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Item number: ABD-13402
A fluorogenic substrate for caspase 3, a protease that is rapidly activated when cells are exposed to apoptotic conditions and that cleaves poly(ADP-ribose) polymerase.
Application: | Caspase-3 substrate |
CAS | 169332-61-0 |
139.00€
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Item number: ABD-13467
The non-fluorescent R110 substrates generate the bright green fluorescent rhodamine 110 product that has Ex/Em = 494/521 nm, and can be easily detected with a FITC filter set. In general, R110 substrates are much more sensitive than the AMC-, AFC- or 4-nitroaniline-based substrates. This R110 substrate is used for...
Application: | Protease substrate |
139.00€
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Item number: Cay17598-50
3,3',5'-Triiodo-L-thyronine, also known as reverse T3 (rT3), is a thyroid hormone generated by deiodination of the prohormone thyroxine. It is about 1,000-fold less active at the thyroid hormone receptors TRalpha and TRbeta than 3,3',5-triiodo-L-thyronine (Cay-16028) and commonly described as inactive. However, high...
Keywords: | 3,3',5'-T3, Reverse T3, rT3, O-(4-hydroxy-3,5-diiodophenyl)-3-iodo-L-tyrosine |
Application: | TR Delta alpha1 activator |
CAS | 5817-39-0 |
MW: | 651 D |
From 114.00€
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Item number: Cay17150-25
Angiotensin II is a peptide hormone known best as a vasoconstrictor with central roles in chronic hypertension, heart failure, and stroke. It is an octapeptide typically generated by the removal of two residues from angiotensin I by angiotensin-converting enzyme (ACE). Angiotensin II is a ligand for at least two...
Keywords: | 5-L-isoleucine-angiotensin II, acetate |
Application: | Peptide hormone |
CAS | 68521-88-0 |
MW: | 1046.2 D |
From 34.00€
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Item number: Cay11442-1
Tentoxin is a cyclic tetrapeptide first isolated from the plant pathogen A. alternata. It is an herbicide that inhibits chloroplast development, resulting in chlorotic tissue. Tentoxin is selectively phytotoxic, as it kills a number of important weeds at concentrations that have no effects on several important...
Keywords: | cyclo[N-methyl-L-alanyl-L-leucyl-(alphaZ)-alpha,beta-didehydro-N-methylphenylalanylglycyl] |
Application: | Herbicide, chloroplast development inhibitor |
CAS | 28540-82-1 |
MW: | 414.5 D |
From 259.00€
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Item number: Cay24204-1
Glucagon is a peptide hormone produced from proglucagon in pancreatic alpha cells that has a role in the regulation of glucose metabolism. Pulsatile application of glucagon to rat hepatocytes stimulates glucose production ex vivo. It also stimulates glucose output from perfused rat livers via increases in...
Keywords: | glucagon (swine) |
Origin: | swine |
CAS | 19179-82-9 |
MW: | 3482.8 D |
From 117.00€
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Item number: BPS-40560
PI/PS (4:1, w/w) unilamellar vesicle, prepared with L-alpha-phosphatidylinositol (Liver, Bovine) (sodium salt) and L-alpha-phosphatidylserine (Brain, Porcine) (sodium salt). Lipid monolayer was formed by sonication. Application: Useful as a substrate for PI-3 kinase activity assays and other lipid kinases....
Application: | PI-3 kinase substrate |
569.00€
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Item number: Cay40972-1
Survodutide is a dual peptide agonist of the glucagon-like peptide 1 receptor (GLP-1R) and glucagon receptor (GCGR). It increases cAMP accumulation in CHO-K1 cells expressing GLP-1R or GCGR in reporter assays (EC50s = 0.33 and 0.52 nM, respectively) and potentiates glucose-induced insulin secretion in isolated...
Keywords: | BI-456906,... |
Application: | GLP-1R / GCGR dual peptide agonist |
CAS | 2805997-46-8 |
MW: | 4231.7 D |
From 88.00€
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Item number: Cay41249-1
Glucagon-like peptide 1 (GLP-1) (28-36) amide is a peptide and an active metabolite of the endogenous GLP-1R agonist GLP-1 (7-36) amide (Cay-15069). It is formed from GLP-1 (7-36) amide by neprilysin (NEP). GLP-1 (28-36) amide (100 nM) inhibits decreases in ATP levels induced by hydrogen peroxide and increases in...
Keywords: | Glucagon-like Peptide 1 (28-36) amide, Phe-Ile-Ala-Trp-Leu-Val-Lys-Gly-Arg-NH2,... |
Application: | Peptide, active GLP-1 (7-36) amide metabolite |
MW: | 1088.4 D |
From 38.00€
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Item number: Cay41259-1
Dapiglutide is a dual glucagon-like peptide 1 receptor (GLP-1R) and GLP-2R agonist. It induces cAMP accumulation in HEK293 cells expressing human GLP-1R or GLP-2R (EC50s = 190 and 210 pM, respectively). Dapiglutide (6 nmol/kg) reduces peak blood glucose levels in an oral glucose tolerance test and increases...
Keywords: | L-histidyl-2-methylalanyl-L-alpha-glutamylglycyl-L-seryl-L-phenylalanyl-L-threonyl-L-seryl-L-alpha-glutamyl-L-leucyl-L-ala... |
Application: | Dual GLP-1R / GLP-2R agonist |
MW: | 4166.8 D |
From 254.00€
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