- Search results for 6553-1
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12 products were found matching "6553-1"!
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Item number: Cay16553-1
Checkpoint kinase 1 (Chk1) regulates S and G2-M phase cell cycle checkpoints in response to DNA damage. CHIR124 is a cell-permeable, quinolone-based inhibitor of Chk1 (IC50 = 0.3 nM in vitro). It demonstrates high selectivity for Chk1 by displaying inhibitory values 2,000-fold higher against Chk2 (IC50 = 0.7 µM). In...
Keywords: | 4-[(3S)-1-azabicyclo[2.2.2]oct-3-ylamino]-3-(1H-benzimidazol-2-yl)-6-chloro-2(1H)-quinolinone |
Application: | Cell-permeable Chk1 inhibitor |
CAS | 405168-58-3 |
MW: | 419.9 D |
From 48.00€
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Item number: VRPS-6553
Primers are provided as a 40 µl solution containing both primers at a final concentration of 50 µM in 10 mM Tris-HCl (pH 7.5), 0.1 mM EDTA. Dilute with water as needed prior to use. This amount is sufficient for 1000 x 20µl PCR reactions assuming a final primer concentration of 0.1 µM. Add cDNA template....
Keywords: | Tsen2, EC=3.1.27.9, tRNA-intron endonuclease Sen2, tRNA-splicing endonuclease subunit Sen2 |
Application: | RNA quantification |
52.00€
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Item number: Cay31849-1
Leptin is a peptide hormone that regulates energy homeostasis, growth, and reproduction, as well as immune function. It is secreted by adipocytes and regulated by nutritional status, where fasting reduces leptin levels and feeding increases leptin levels, as well as in a circadian manner, with serum levels peaking...
Keywords: | Obese protein, Obese protein, Obesity factor, Obesity factor, Leptin {ECO:0000312|HGNC:HGNC:6553}, Leptin... |
Application: | Active, Cell culture |
Expressed in: | E.coli |
Origin: | human |
From 86.00€
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Item number: E-AB-65553.120
Metabolic N-oxidation of the diet-derived amino-trimethylamine (TMA) is mediated by flavin-containing monooxygenase and is subject to an inherited FMO3 polymorphism in man resulting in a small subpopulation with reduced TMA N-oxidation capacity resulting in fish odor syndrome Trimethylaminuria. Three forms of the...
Keywords: | Anti-FMO5, Anti-FMO 5, EC=1.14.13.8, Anti-Dimethylaniline oxidase 5, Anti-Hepatic flavin-containing monooxygenase 5,... |
Application: | WB |
Host: | Rabbit |
Species reactivity: | human, mouse, rat |
From 198.00€
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Item number: E-AB-61553.120
This gene encodes a protein that contains a ubiquitin associated domain at the N-terminus, an SH3 domain, and a C-terminal domain with similarities to the catalytic motif of phosphoglycerate mutase. The encoded protein was found to inhibit endocytosis of epidermal growth factor receptor (EGFR) and platelet-derived...
Keywords: | Anti-STS-1, Anti-TULA-2, Anti-UBASH3B, Anti-KIAA1959, EC=3.1.3.48, Anti-T-cell ubiquitin ligand 2, Anti-Cbl-interacting... |
Application: | WB, IHC, IF |
Host: | Rabbit |
Species reactivity: | human, mouse, rat |
From 198.00€
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Item number: ABE-32-6553-10
Source: Escherichia Coli.Sterile Filtered colorless solution.Transforming growth factor betas (TGFBetas) mediate many cell-cell interactions which occur during embryonic development. Three TGFBetas have been identified in mammals. TGFBeta1, TGFBeta2 and TGFBeta3 are each synthesized as precursor proteins which are...
Expressed in: | E.coli |
Origin: | mouse |
From 438.00€
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Item number: Cay26553-25
Palmitoyl-L-carnitine is a long-chain acylcarnitine and an isomer of palmitoyl-DL-carnitine (Cay-11095) and palmitoyl-D-carnitine (Cay-26552). Palmitoyl-L-carnitine is transported into mitochondria via carnitine palmitoyl transferase II to deliver palmitate for fatty acid oxidation and energy production. It inhibits...
Keywords: | Hexadecanoyl-L-carnitine, L-Hexadecanoylcarnitine, L-Palmitoylcarnitine,... |
Application: | Carnitine palmitoyltransferase II inhibitor |
CAS | 18877-64-0 |
MW: | 436.1 D |
From 158.00€
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Item number: E-AB-65453.120
The protein encoded by this gene is the large subunit (p127) of the heterodimeric DNA damage-binding (DDB) complex while another protein (p48) forms the small subunit. This protein complex functions in nucleotide-excision repair and binds to DNA following UV damage. Defective activity of this complex causes the...
Keywords: | Anti-XAP1, Anti-XPCe, Anti-DDB1, Anti-DDBa, Anti-XAP-1, Anti-XPE-BF, Anti-UV-DDB 1, Anti-DDB p127 subunit,... |
Application: | WB |
Host: | Rabbit |
Species reactivity: | human, mouse, rat |
From 198.00€
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Item number: E-AB-65593.120
This gene is the human homolog of murine plunc, and like the mouse gene, is specifically expressed in the upper airways and nasopharyngeal regions. The encoded antimicrobial protein displays antibacterial activity against Gram-negative bacteria. It is thought to be involved in inflammatory responses to irritants in...
Keywords: | Anti-LUNX, Anti-BPIFA1, Anti-SPLUNC1, Anti-Short PLUNC1, Anti-Von Ebner protein Hl, Anti-Lung-specific protein X,... |
Application: | WB |
Host: | Rabbit |
Species reactivity: | mouse, rat |
From 198.00€
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Item number: E-AB-65530.120
The protein encoded by this gene is a member of a family of RNA-binding proteins, has three RNA recognition motifs (RRMs), and binds adenine and uridine-rich elements in mRNA and pre-mRNAs of a wide range of genes. It regulates various activities including translational control, splicing and apoptosis. Alternate...
Keywords: | Anti-TIAL1, Anti-Nucleolysin TIAR, Anti-TIA-1-related protein, TIAL1 Polyclonal Antibody |
Application: | WB |
Host: | Rabbit |
Species reactivity: | human |
From 198.00€
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Item number: E-AB-65538.120
This gene encodes an enzyme which catalyzes a key step in the biosynthesis of nicotinamide adenine dinucleotide (NAD). The encoded enzyme is one of several nicotinamide nucleotide adenylyltransferases, and is specifically localized to the cell nucleus. Activity of this protein leads to the activation of a nuclear...
Keywords: | Anti-NMNAT, Anti-NMNAT1, EC=2.7.7.1, EC=2.7.7.18, Anti-NMN adenylyltransferase 1, Anti-NaMN adenylyltransferase 1,... |
Application: | WB |
Host: | Rabbit |
Species reactivity: | mouse, rat |
From 198.00€
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Item number: E-AB-65532.120
The protein encoded by this gene is a member of the ELAVL family of RNA-binding proteins that contain several RNA recognition motifs, and selectively bind AU-rich elements (AREs) found in the 3' untranslated regions of mRNAs. AREs signal degradation of mRNAs as a means to regulate gene expression, thus by binding...
Keywords: | Anti-HUR, Anti-HuR, Anti-ELAVL1, Anti-Hu-antigen R, Anti-ELAV-like protein 1, ELAVL1 Polyclonal Antibody |
Application: | WB, IHC |
Host: | Rabbit |
Species reactivity: | human, mouse |
From 218.00€
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