Palmitoyl-L-carnitine (chloride)

Palmitoyl-L-carnitine is a long-chain acylcarnitine and an isomer of palmitoyl-DL-carnitine (Cay-11095) and palmitoyl-D-carnitine (Cay-26552). Palmitoyl-L-carnitine is transported into mitochondria via carnitine palmitoyl transferase II to deliver palmitate for fatty acid oxidation and energy production. It inhibits lecithin:cholesterol acyltransferase activity in isolated rat, but not human, plasma when used at a concentration of 500 µM. Serum and hepatic levels of palmitoyl-L-carnitine are increased in mice during cold exposure, and it is taken up by brown adipose tissue. Palmitoyl-L-carnitine also protects against age-induced cold sensitivity in mice.Formal Name: 3-carboxy-N,N,N-trimethyl-2R-[(1-oxohexadecyl)oxy]-1-propanaminium, monochloride. CAS Number: 18877-64-0. Synonyms: CAR 16:0, C16:0 Carnitine, L-Carnitine hexadecanoyl ester, L-Carnitine palmitoyl ester, L-Hexadecanoylcarnitine, Hexadecanoyl-L-carnitine, L-Palmitoylcarnitine. Molecular Formula: C23H46NO4 . Cl. Formula Weight: 436.1. Purity: >95%. Formulation: (Request formulation change), A crystalline solid. Solubility: Water: slightly, heated, sonicated. lambdamax: 212 nm. SMILES: OC(C[C@H](C[N+](C)(C)C)OC(CCCCCCCCCCCCCCC)=O)=O.[Cl-]. InChi Code: InChI=1S/C23H45NO4.ClH/c1-5-6-7-8-9-10-11-12-13-14-15-16-17-18-23(27)28-21(19-22(25)26)20-24(2,3)4,/h21H,5-20H2,1-4H3,1H/t21-,/m1./s1. InChi Key: GAMKNLFIHBMGQT-ZMBIFBSDSA-N.