Products from TargetMol
TargetMol, based in Boston, Massachusetts, was founded in 2015 and is a drug screening expert in the life science community. The company offers diverse compound libraries, including FDA-approved libraries, and covers a broad spectrum of small molecule compounds such as inhibitors and agonists as well as recombinant proteins and natural products. TargetMol's products are used by researchers worldwide in areas such as cancer research, neurobiology, inflammation, immunology and metabolism.
More information at: www.targetmol.com
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AFD-21
Item number: TGM-T23652-100mg
Description: AFD-21 is a class I antiarrhythmic drug. It binds to sodium channels in their inactivated state and exerts use- and voltage-dependent inhibition of sodium channels with unbinding rates comparable to those of class I antiarrhythmic drugs with moderate kinetics. Target: Others. Smiles:...
| Keywords: | NS-2 Class 1 antiarrhythmic agent, AFD21 |
| CAS | 99465-44-8 |
| MW: | 469.61 D |
From 1,440.00€
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Afegostat HCl
Item number: TGM-T23653-100mg
Description: Afegostat is an acid beta-glucosidase (GCase) active site inhibitor that acts as a pharmacological chaperone. Afegostat inhibits GCase with K(i) ~30 nM for wild-type and mutant enzymes. Afegostat was an experimental drug for the treatment of certain forms of Gaucher's disease. Target: Others. Smiles:...
| Keywords: | AT-2101, Afegostat hydrochloride, AT2101, Afegostat |
| CAS | 161302-93-8 |
| MW: | 183.63 D |
From 1,440.00€
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Afeletecan free base
Item number: TGM-T23654-25mg
Description: Afeletecan is a water-soluble camptothecin derivative. Afeletecan stabilizes the topoisomerase I-DNA covalent complex and forms an enzyme-drug-DNA ternary complex. Both the initial cleavage reaction and religation steps are inhibited and subsequent collision of the replication fork with the cleaved...
| Keywords: | BAY56-3722, BAY 56-3722, BAY-563722, Afeletecan |
| CAS | 215604-75-4 |
| MW: | 895.98 D |
1,440.00€
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AFK-108
Item number: TGM-T23655-100mg
Description: AFK-108 is a fungicide agent. Target: Others. Smiles: C(CN1C=CN=C1)(OC/C=C(/CCC=C(C)C)\C)C2=C(Cl)C=C(Cl)C=C2. References: Hori K, Sakaguchi A, Kudoh M, Ishida K, Aoyama Y, Yoshida Y. Structure-activity relationships of a new antifungal imidazole, AFK-108, and related compounds. Chem Pharm Bull (Tokyo)....
| CAS | 135330-85-7 |
| MW: | 393.35 D |
From 1,440.00€
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VUF11211
Item number: TGM-T23656-100mg
Description: VUF11211 is an effective antagonist of CXCR3 that acts by extending from the minor pocket into the major pocket of the transmembrane domains. Target: Others. Smiles: C(C)[C@@H]1N(CCN(C1)C2=C(Cl)C=C(C(NCC)=O)C=N2)C3CCN(CC4=CC=C(Cl)C=C4)CC3. References: Ganghammer S, Gutjahr J, Hutterer E, Krenn PW,...
| Keywords: | VUF 11211, VUF-11211 |
| CAS | 906556-51-2 |
| MW: | 504.49 D |
From 1,440.00€
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AFP-07
Item number: TGM-T23657-100mg
Description: AFP-07 is a highly selective and potent agonist. It was used for the prostacyclin receptor. Target: Others. Smiles: [Na].[H][C@]12C[C@@H](O)[C@H](\C=C\[C@@H](O)[C@@H](C)CC#CCC)[C@@]1([H])C(F)(F)\C(O2)=C\CCCC(O)=O. References: Chang CS, Negishi M, Nakano T, Morizawa Y, Matsumura Y, Ichikawa A....
| Keywords: | AFP07 |
| CAS | 171232-82-9 |
| MW: | 435.464 D |
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Afurolol
Item number: TGM-T23658-100mg
Description: Alfurolol is a beta-blocker. Target: Others. Smiles: O(CC(CNC(C)(C)C)O)C1=C2C(COC2=O)=CC=C1
| Keywords: | Afurololum |
| CAS | 65776-67-2 |
| MW: | 279.33 D |
From 1,440.00€
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AG 84-10
Item number: TGM-T23659-25mg
Description: AG 84-10 is similar to Angiotensinogen 6-13. It is a peptidic substrate analog. It also has antihypertensive effects. Target: Others. Smiles: C(N[C@@H](CC1=CC=CC=C1)C(N[C@@H](CC2=CN=CN2)C(N[C@H](C(N[C@H](C(N[C@@H](CC3=CC=C(O)C=C3)C(O)=O)=O)C(C)C)=O)CC(C)C)=O)=O)(=O)[C@H]4N(C(C)=O)CCC4. References: Labbé...
| Keywords: | AG84-10, AG-84-10 |
| CAS | 121520-99-8 |
| MW: | 816.94 D |
Please request pricing for this article.
Tipiracil hydrochloride
Item number: TGM-T2366-100mg
Description: Tipiracil hydrochloride (MA-1 hydrochloride) is a thymidine phosphorylase inhibitor (TPI). Tipiracil hydrochloride is one of the active components in TAS-102, which is an anticancer drug candidate currently in clinical trials. Target: Nucleoside Antimetabolite/Analog. Smiles:...
| Keywords: | MA-1 hydrochloride |
| CAS | 183204-72-0 |
| MW: | 279.12 D |
From 30.00€
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AG1433
Item number: TGM-T23660-100mg
Description: AG1433 is a tyrosine kinases inhibitor that acts as a direct and selective inhibitor of photosynthetic PEP carboxylase and an inhibitor of PDGFR-beta, Flk-1, and angiogenesis. Target: Others. Smiles: Cl.Cc1cc2ncc(nc2cc1C)-c1ccc(O)c(O)c1. References: Serban F, Daianu O, Tataranu LG, Artene SA, Emami G,...
| Keywords: | Tyrphostin AG1433, Tyrphostin AG-1433, AG-1433, Tyrphostin AG 1433, AG 1433 |
| CAS | 168836-03-1 |
| MW: | 302.76 D |
From 1,440.00€
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Agamanone
Item number: TGM-T23661-100mg
Description: Agamanone is an anticancer agent. It also has antioxidant and chemopreventive properties. Target: Others. Smiles: OC1=C2C(O[C@@H](CC2=O)C=3C=C4C(=C(OC)C3)OCO4)=CC(O)=C1OC
| CAS | 143381-59-3 |
| MW: | 360.31 D |
From 1,440.00€
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Aganodine
Item number: TGM-T23662-100mg
Description: Aganodine is a guanidine that activates presynaptic imidazoline receptors. Aganodine inhibits the presynaptic release of norepinephrine through its agonism at imidazoline receptors. Target: Others. Smiles: ClC1=C2C(=C(Cl)C=C1)CN(NC(=N)N)C2. References: Molderings GJ, Bönisch H, Hammermann R, Göthert M,...
| Keywords: | Aganodin |
| CAS | 86696-87-9 |
| MW: | 245.11 D |
From 1,583.00€
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