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Description: VUF11211 is an effective antagonist of CXCR3 that acts by extending from the minor pocket into the major pocket of the transmembrane domains. Target: Others. Smiles: C(C)[C@@H]1N(CCN(C1)C2=C(Cl)C=C(C(NCC)=O)C=N2)C3CCN(CC4=CC=C(Cl)C=C4)CC3. References: Ganghammer S, Gutjahr J, Hutterer E, Krenn PW, Pucher S, Zelle-Rieser C, Jöhrer K, Wijtmans M, Leurs R, Smit MJ, Gattei V, Greil R, Hartmann TN. Combined CXCR3/CXCR4 measurements are of high prognostic value in chronic lymphocytic leukemia due to negative co-operativity of the receptors. Haematologica. 2016 Mar,101(3):e99-102. doi: 10.3324/haematol.2015.133470. Epub 2015 Nov 20. PubMed PMID: 26589908, PubMed Central PMCID: PMC4815737.
This website uses cookies, which are necessary for the technical operation of the website and are always set. Other cookies, which increase the usability of this website, serve for direct advertising or simplify interaction with other websites and social networks, will only be used with your consent.
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