Products from SYNkinase
SYNkinase, headquartered in Australia, is a primary producer of research-use-only biomedical reagents, which it markets to life-science and drug-discovery researchers affiliated with universities, research institutes and industry. SYNkinase was established in 2008 by Professor Andrew Wilks and Dr. Xian Bu. The founders of the company have been involved in pharmaceutical drug discovery for three decades and have extensive scientific, company and board experience.
More information at: www.adipogen.com/synkinase
No results were found for the filter!
BGG463
Item number: SYN-1226-M001
BGG463 (NVP-BGG463) was generated by a rational 'hybrid design' approach. Like Imatinib, BGG463 disrupts the assembly of the hydrophobic spine, a characteristic feature of the active state of several kinases, thereby locking the kinase in an inactive 'DFG-out' conformation. BGG463 can inhibit c-ABL-T334I, BCR-ABL...
| Keywords: | BGG-463 |
| Application: | Kinase active state disruptor |
| CAS | 890129-26-7 |
| MW: | 578.6 D |
From 250.00€
*
(+)-JQ1
Item number: SYN-3004-M001
Soluble in DMSO or ethanol. (+)-JQ1 is a potent, high affinity, selective BET bromodomain inhibitor (IC(50) values of 17.7, 32.6, 76.9 and 12942nM respectively for BRD2 (N-terminal (N)), BRD4 (C-terminal (C)), BRD4 (N) and CREBBP, respectively. Target: BET bromodomain
| Application: | BET bromodomain inhibitor |
| CAS | 1268524-70-4 |
| MW: | 457 D |
From 165.00€
*