11 products were found matching "P05541"!

Protein function: Identifies cytotoxic/suppressor T-cells that interact with MHC class I bearing targets. CD8 is thought to play a role in the process of T-cell mediated killing. [The UniProt Consortium]

The human lymphocyte differentiation antigen CD8 is encoded by a single gene that gives rise to a 33- to 34-kDa glycoprotein expressed on the cell surface as a dimer and in higher molecular mass forms. Protein function: Integral membrane glycoprotein that plays an essential role in the immune response and serves...

The 341 monoclonal antibody specifically reacts with the beta chain of the Rat CD8 molecule. The alpha and beta chains of the CD8 molecule form a heterodimer common on most thymocytes. The CD8 positive T cells of athymic rats and most NK cells express a homodimer composed solely of CD8a. It is reported that...

Protein function: Identifies cytotoxic/suppressor T-cells that interact with MHC class I bearing targets. CD8 is thought to play a role in the process of T-cell mediated killing. [The UniProt Consortium]

Protein function: Identifies cytotoxic/suppressor T-cells that interact with MHC class I bearing targets. CD8 is thought to play a role in the process of T-cell mediated killing. [The UniProt Consortium]

The beta chain of the rat CD8 cell surface antigen is expressed on thymocytes and peripheral cytotoxic/suppressor cells. CD8 beta is not expressed by NK cells or by intestinal intraepithelial T cells. Reported to block proliferative and cytotoxic responses of CD8 +ve effector cells in vitro. Applications: Suitable...

Source:, Recombinant Rat from E. coli, Purity: >95%, Endotoxin: 1.0EU per 1ug (determined by the LAL method), Accession No: P05541, Fragment: Ala21~Lys208 (Accession No: P05541), Sequence: MGHHHHHHSG SEF-ALLQTPSSLL VQTNQTAKMS CEAKTFPKGT TIYWLRELQD SNKNKHFEFL ASRTSTKGIK YGERVKKNMT LSFNSTLPFL KIMDVKPEDS GFYFCAMVGS...

Protein function: Integral membrane glycoprotein that plays an essential role in the immune response and serves multiple functions in responses against both external and internal offenses. In T-cells, functions primarily as a coreceptor for MHC class I molecule:peptide complex. The antigens presented by class I...

Protein function: Integral membrane glycoprotein that plays an essential role in the immune response and serves multiple functions in responses against both external and internal offenses. In T-cells, functions primarily as a coreceptor for MHC class I molecule:peptide complex. The antigens presented by class I...

Protein function: Integral membrane glycoprotein that plays an essential role in the immune response and serves multiple functions in responses against both external and internal offenses. In T-cells, functions primarily as a coreceptor for MHC class I molecule:peptide complex. The antigens presented by class I...

The CD8b (CD8 beta) subunit of CD8 T cell coreceptor is expressed in CD8 alpha/beta heterodimers on majority of MHC I-restricted conventional T cells and thymocytes and in CD8 alpha/alpha homodimers on subsets of memory T cells, intraepithelial lymphocytes, NK cells, macrophages, mast cells, and dendritic cells....