- Search results for K07747
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21 products were found matching "K07747"!
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Item number: NSJ-F49441-0.08ML
In 1X PBS, pH 7.4, with 0.09% sodium azide. Cerebral deposition of amyloid beta peptide is an early and critical feature of Alzheimer's disease and a frequent complication of Down syndrome. Amyloid beta peptide is generated by proteolytic cleavage of amyloid precursor protein by 2 proteases, one of which is the...
Keywords: | Anti-DRAP, Anti-ASP1, Anti-BACE2, Anti-CDA13, Anti-AEPLC, Anti-Asp 1, Anti-Memapsin-1, EC=3.4.23.45, Anti-Theta-secretase,... |
Application: | WB, FC, ELISA |
Host: | Rabbit |
Species reactivity: | human |
From 326.00€
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Item number: G-HUFI01631.96
Application: | ELISA |
Species reactivity: | human |
641.00€
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Item number: NSJ-F40129-0.08ML
In 1X PBS, pH 7.4, with 0.09% sodium azide. Amyloid-beta peptide aggregation is a signature of Alzheimer disease and a frequent complication of adult Down syndrome patients. Amyloid-beta is generated by proteolytic processing of the amyloid precursor protein (APP) by beta- and gamma-secretase at the N and C termini,...
Keywords: | Anti-DRAP, Anti-ASP1, Anti-BACE2, Anti-CDA13, Anti-AEPLC, Anti-Asp 1, Anti-Memapsin-1, EC=3.4.23.45, Anti-Theta-secretase,... |
Application: | WB, IHC, ELISA |
Host: | Rabbit |
Species reactivity: | human |
From 326.00€
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Item number: E-AB-53590.120
This gene encodes an integral membrane glycoprotein that functions as an aspartic protease. The encoded protein cleaves amyloid precursor protein into amyloid beta peptide, which is a critical step in the etiology of Alzheimer's disease and Down syndrome. The protein precursor is further processed into an active...
Keywords: | Anti-ASP1, Anti-DRAP, Anti-BACE2, Anti-Asp 1, Anti-AEPLC, Anti-CDA13, Anti-Memapsin-1, Anti-Theta-secretase,... |
Application: | IHC, ELISA |
Host: | Rabbit |
Species reactivity: | human, mouse, rat |
From 71.00€
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Item number: G-CAB14864.100
WB 1:500 - 1:2000. Protein function: Responsible for the proteolytic processing of the amyloid precursor protein (APP). Cleaves APP, between residues 690 and 691, leading to the generation and extracellular release of beta-cleaved soluble APP, and a corresponding cell-associated C- terminal fragment which is later...
Keywords: | Anti-DRAP, Anti-ASP1, Anti-AEPLC, Anti-Asp 1, Anti-CDA13, Anti-BACE2, Anti-Memapsin-1, Anti-Theta-secretase,... |
Application: | WB |
Host: | Rabbit |
Species reactivity: | human |
From 352.00€
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Item number: ATA-HPA035416.100
Protein function: Responsible for the proteolytic processing of the amyloid precursor protein (APP). Cleaves APP, between residues 690 and 691, leading to the generation and extracellular release of beta-cleaved soluble APP, and a corresponding cell-associated C-terminal fragment which is later released by...
Keywords: | Anti-ASP1, Anti-DRAP, Anti-CDA13, Anti-AEPLC, Anti-Asp 1, Anti-BACE2, Anti-Memapsin-1, Anti-Theta-secretase,... |
Application: | IHC, WB |
Host: | Rabbit |
Species reactivity: | human |
From 300.00€
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Item number: Cay24934-5
AZD 3293 is an inhibitor of beta-secretase 1 (BACE1) and BACE2 (Kis = 0.4 and 0.8 nM, respectively). It is selective for BACE1 and BACE2 over cathepsin D, gamma-secretase, and human-ether-a-go-go (hERG, IC50s = 3,797, >25,000, and 4,700 nM, respectively). AZD 3293 inhibits the secretion of amyloid-beta (1-40)...
Keywords: | Lanabecestat, LY3314814,... |
Application: | BACE1 / BACE2 inhibitor |
CAS | 1383982-64-6 |
MW: | 412.5 D |
From 88.00€
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Item number: E-AB-90979.120
This gene encodes an integral membrane glycoprotein that functions as an aspartic protease. The encoded protein cleaves amyloid precursor protein into amyloid beta peptide, which is a critical step in the etiology of Alzheimer's disease and Down syndrome. The protein precursor is further processed into an active...
Keywords: | DRAP, ASP1, AEPLC, BACE2, Asp 1, CDA13, Memapsin-1, Theta-secretase, Beta-secretase 2, Aspartyl protease 1, Down region... |
Application: | WB, IF |
Host: | Rabbit |
Species reactivity: | human, mouse, rat |
From 198.00€
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Item number: E-PKSM040382.1
Protein function: Responsible for the proteolytic processing of the amyloid precursor protein (APP). Cleaves APP, between residues 690 and 691, leading to the generation and extracellular release of beta-cleaved soluble APP, and a corresponding cell-associated C- terminal fragment which is later released by...
Origin: | mouse |
From 1,617.00€
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Item number: ELK-ELK9252.48
The test principle applied in this kit is Sandwich enzyme immunoassay. The microtiter plate provided in this kit has been pre-coated with an antibody specific to Rat BACE2. Standards or samples are added to the appropriate microtiter plate wells then with a biotin-conjugated antibody specific to Rat BACE2. Next,...
Keywords: | Bace2, Memapsin-1, Theta-secretase, Beta-secretase 2, Beta-site APP cleaving enzyme 2, Membrane-associated aspartic... |
Application: | ELISA |
Species reactivity: | rat |
From 470.00€
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Item number: ELK-ES11348.100
This gene encodes an integral membrane glycoprotein that functions as an aspartic protease. The encoded protein cleaves amyloid precursor protein into amyloid beta peptide, which is a critical step in the etiology of Alzheimer's disease and Down syndrome. The protein precursor is further processed into an active...
Keywords: | Anti-ASP1, Anti-DRAP, Anti-BACE2, Anti-Asp 1, Anti-AEPLC, Anti-CDA13, Anti-Memapsin-1, Anti-Theta-secretase,... |
Application: | WB, ELISA |
Host: | Rabbit |
Species reactivity: | human, rat, mouse |
From 169.00€
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Item number: ARG54377.50
Protein function: Responsible for the proteolytic processing of the amyloid precursor protein (APP). Cleaves APP, between residues 690 and 691, leading to the generation and extracellular release of beta-cleaved soluble APP, and a corresponding cell-associated C- terminal fragment which is later released by...
Keywords: | Anti-DRAP, Anti-ASP1, Anti-CDA13, Anti-BACE2, Anti-Asp 1, Anti-AEPLC, Anti-Memapsin-1, EC=3.4.23.45, Anti-Theta-secretase,... |
Application: | WB |
Host: | Rabbit |
Species reactivity: | human |
608.00€
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