37 products were found matching "K05742"!

Sodium-hydrogen exchangers (NHE) are involved in maintaining sodium and pH balance in a variety of tissues. They are also known as sodium-hydrogen antiporters and solute carrier family 9 members. 5-(N-ethyl-N-isopropyl)-Amiloride (EIPA) is a potent inhibitor of several NHE isoforms, inhibiting NHE1, NHE2, NHE3, and...

Sodium-hydrogen exchangers (NHE) are involved in maintaining sodium and pH balance in a variety of tissues. They are also known as sodium-hydrogen antiporters and solute carrier family 9 members. 5-(N,N-dimethyl)-Amiloride (DMA) inhibits NHE1, NHE2, and NHE3 with Ki values of 0.02, 0.25, and 14 µM, respectively....

Cariporide is an inhibitor of sodium-hydrogen exchanger 1 (NHE-1, IC50 = 0.56 µM in an intracellular pH recovery assay). It is selective for NHE-1 over NHE-2 (IC50 = 28 µM in an intracellular pH recovery assay). Cariporide inhibits sodium propionate-induced swelling of isolated human platelets (IC50 = 0.023 µM). It...

0.5mg/ml if reconstituted with 0.2ml sterile DI water. NHE1, also known as SLC9A1, is an isoform of sodium-hydrogen antiporter that in humans is encoded by the SLC9A1 gene. It is mapped to 1p36.11. NHE1 is a ubiquitous membrane-bound enzyme involved in pH regulation of vertebrate cells. It is specifically inhibited...

The sodium-hydrogen exchanger isoform-1 (NHE-1) is the most predominant isoform of the Na+/H+ exchanger and is expressed in the heart where it contributes to cardiomyocyte pH homeostasis. It plays an important role in the myocardial response to ischemia-reperfusion. Zoniporide inhibits human NHE-1 with an IC50 value...

KR-32568 is an inhibitor of the sodium-hydrogen exchanger isoform-1 (NHE-1, IC50 = 230 nM). It restores cardiac contractile function ex vivo in an isolated ischemic rat heart model when used at a concentration of 10 µM. KR-32568 (0.3 mg/kg) reduces myocardial infarct size in a rat model of ischemia and reperfusion...

BI-9627 is an inhibitor of sodium-hydrogen exchanger isoform 1 (NHE1), with IC50 values of 6 and 31 nM in intracellular pH recovery (pHi) and human platelet swelling assays, respectively. It is greater than 30-fold selective for NHE1 over NHE2 and is inactive at NHE3 up to 16 µM in a pHi assay. BI-9627 inhibits...

Anti-Nhe-1 Antibody was affinity purified from monospecific antiserum by immunoaffinity chromatography. Cross reactivity with Nhe-1 from other sources has not been determined. Protein function: Involved in pH regulation to eliminate acids generated by active metabolism or to counter adverse environmental conditions....

Anti-Nhe-1 Antibody was affinity purified from monospecific antiserum by immunoaffinity chromatography. Cross reactivity with Nhe-1 from other sources has not been determined. Protein function: Involved in pH regulation to eliminate acids generated by active metabolism or to counter adverse environmental conditions....

Protein function: Involved in pH regulation to eliminate acids generated by active metabolism or to counter adverse environmental conditions. Major proton extruding system driven by the inward sodium ion chemical gradient. Plays an important role in signal transduction. [The UniProt Consortium] Buffer: 40% glycerol...

Protein function: Involved in pH regulation to eliminate acids generated by active metabolism or to counter adverse environmental conditions. Major proton extruding system driven by the inward sodium ion chemical gradient. Plays an important role in signal transduction. [The UniProt Consortium] Buffer: 40% glycerol...

Protein function: Involved in pH regulation to eliminate acids generated by active metabolism or to counter adverse environmental conditions. Major proton extruding system driven by the inward sodium ion chemical gradient. Plays an important role in signal transduction. {ECO:0000269, PubMed:11350981, ECO:0000269,...