20 products were found matching "K04320"!

The test principle applied in this kit is Sandwich enzyme immunoassay. The microtiter plate provided in this kit has been pre-coated with an antibody specific to Human MCHR1. Standards or samples are added to the appropriate microtiter plate wells then with a biotin-conjugated antibody specific to Human MCHR1. Next,...

GW 803430 is an antagonist of melanin-concentrating hormone receptor 1 (MCH1, IC50 = 0.5 nM). It reduces cumulative body weight and food intake in diet-induced obese rats when administered at doses of 1 and 3 mg/kg. GW 803430 (10 and 30 mg/kg) decreases marble-burying behavior in mice, indicating anxiolytic...

MCHR1, a member of the G protein coupled receptor family 1, is an integral plasma membrane protein which binds melanin concentrating hormone. MCHR1 can inhibit cAMP accumulation and stimulate intracellular calcium flux, and is probably involved in the neuronal regulation of food consumption. Although structurally...

SNAP 94847 is an antagonist of melanin-concentrating hormone receptor 1 (MHC1, Ki = 2.2 nM for the recombinant rat receptor). It is selective for MHC1 over alpha1A-adrenergic and dopamine D2 receptors (Kis = 180 and 7,400 nM, respectively, for the recombinant human receptors). SNAP 94847 (20 mg/kg) increases the...

Protein function: Receptor for melanin-concentrating hormone, coupled to both G proteins that inhibit adenylyl cyclase and G proteins that activate phosphoinositide hydrolysis. [The UniProt Consortium]

[Ala17]-MCH is a synthetic peptide derived from the hypothalamic neuropeptide hormone melanin-concentrating hormone (MCH) and an MCH receptor agonist. It binds to MCH1 and MCH2 receptors in CHO cells expressing the human receptors (IC50s = 0.15 and 3.5 nM, respectively) and induces calcium mobilization in HEK293...

The protein encoded by this gene, a member of the G protein-coupled receptor family 1, is an integral plasma membrane protein which binds melanin-concentrating hormone. The encoded protein can inhibit cAMP accumulation and stimulate intracellular calcium flux, and is probably involved in the neuronal regulation of...

melanin concentrating hormone receptor 1(MCHR1) Homo sapiens The protein encoded by this gene, a member of the G protein-coupled receptor family 1, is an integral plasma membrane protein which binds melanin-concentrating hormone. The encoded protein can inhibit cAMP accumulation and stimulate intracellular calcium...

Primers are provided as a 40 µl solution containing both primers at a final concentration of 50 µM in 10 mM Tris-HCl (pH 7.5), 0.1 mM EDTA. Dilute with water as needed prior to use. This amount is sufficient for 1000 x 20µl PCR reactions assuming a final primer concentration of 0.1 µM. Add cDNA template....

The protein encoded by this gene, a member of the G protein-coupled receptor family 1, is an integral plasma membrane protein which binds melanin-concentrating hormone. The encoded protein can inhibit cAMP accumulation and stimulate intracellular calcium flux, and is probably involved in the neuronal regulation of...

The protein encoded by this gene, a member of the G protein-coupled receptor family 1, is an integral plasma membrane protein which binds melanin-concentrating hormone. The encoded protein can inhibit cAMP accumulation and stimulate intracellular calcium flux, and is probably involved in the neuronal regulation of...