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Item number: Cay34360-25

8(S)-HETE is a major lipoxygenase product in PMA-treated murine epidermis. It activates mouse keratinocyte protein kinase C with an IC50 of 100 µM. 8(S)-HETE also activates PPARalpha selectively at concentrations as low as 0.3 µM. Stereochemical assignment of the (S) enantiomer is based on comparison of chiral HPLC...

Keywords:	8S-hydroxy-5Z,9E,11Z,14Z-eicosatetraenoic acid
Application:	Bioactive lipid assays
CAS	98462-03-4
MW:	320.5 D

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