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GDC-0941
Item number: Cay11600-10
The phosphatidylinositol 3-kinase (PI3K) signaling pathway has central roles in cell growth, development, and survival. GDC-0941 is a potent pan inhibitor of class I catalytic subunits of PI3K, inhibiting p110alpha, beta, delta, and gamma with IC50 values of 3, 33, 3, and 75 nM, respectively. It is much less...
| Keywords: | GNE-0941, Pictilisib, Pictrelisib,... |
| Application: | PI3K inhibitor |
| CAS | 957054-30-7 |
| MW: | 513.6 D |
From 180.00€
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GDC-0941
Item number: SYN-1041-M001
Soluble in DMSO. Slightly soluble (<1mg/ml) in ethanol. GDC-0941 is a potent class I PI3 kinase (PI3K) inhibitor. It selectively binds to PI3K isoforms in an ATP-competitive manner. It has an IC(50) of 3nM, and shows slight selectivity toward p110beta (11-fold) and p110gamma (25-fold). Target: PI3K , Kinase Group:...
| Keywords: | GDC0941 |
| Application: | PI3K inhibitor |
| CAS | 957054-30-7 |
| MW: | 513,6 D |
From 106.00€
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GDC-0941, Free Base (Pictilisib, Pictrelisib, GNE-0941,...
Item number: LC-G-9252_100mg
Soluble in DMSO at 66 mg/mL, very poorly soluble in ethanol, very poorly soluble in water, maximum solubility in plain water is estimated to be about 10-50 µM, buffers, serum, or other additives may increase or decrease the aqueous solubility
| Keywords: | GNE-0941, Pictilisib, Pictrelisib,... |
| Application: | PI3K inhibitor |
| CAS | 957054-30-7 |
| MW: | 513,64 D |
From 86.00€
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GDC-0941
Item number: LKT-G124082.5
pan-PI3K inhibitor.
| Keywords: | GNE-0941, Pictilisib, Pictrelisib, RG7321 |
| Application: | Class I selective PI3K Inhibitor |
| CAS | 957054-30-7 |
| MW: | 513.64 D |
From 108.00€
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