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IOX2
IOX2

Item number: Cay11573-10

IOX2 is an inhibitor of hypoxia-inducible factor prolyl hydroxylase 2 (HIF-PH2, IC50 = 21 nM) with over 100-fold selectivity compared to inhibition of JMJD2A, JMJD2C, JMJD2E, JMJD3, or the 2OG oxygenase FIH (IC50s > 100 µM). IOX2 is active in cells, inhibiting HIF-1alpha hydroxylation in RCC4 cells at 50 µM. See the...
Keywords: N-[[1,2-dihydro-4-hydroxy-2-oxo-1-(phenylmethyl)-3-quinolinyl]carbonyl]-glycine
Application: PHD2 inhibitor
CAS 931398-72-0
MW: 352.3 D
From 92.00€ *
Review
IOX2
IOX2

Item number: LKT-I5992.100

IOX2 is an inhibitor of prolyl hydroxylase that activates HIF-1 and as a result, exhibits pro-angiogenic activity.
Application: PHD2 inhibitor
CAS 931398-72-0
MW: 352.34 D
From 104.00€ *
Review