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Item number: Cay10011249-1

CAY10576 is a multi-kinase inhibitor. It inhibits TANK-binding kinase 1 (TBK1), polo-like kinase 1 (Plk1), and IKKbeta (IC50s =0.093, 0.63, and 0.79 µM, respectively) and is selective for these kinases over IKKepsilon, Aurora B kinase, and cyclin-dependent kinase 2 (Cdk2, IC50s = 5, >5.32 and >30 µM, respectively)....

Keywords:	5-(5,6-dimethoxy-1H-benzimidazol-1-yl)-3-[[2-(methylsulfonyl)phenyl]methoxy]-2-thiophenecarbonitrile
Application:	IKKepsilon inhibitor
CAS	862812-98-4
MW:	469.5 D

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