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Item number: Cay26534-10

Elagolix is an antagonist of the gonadotropin-releasing hormone receptor (GnRHR, Ki = 0.9 nM in a radioligand binding assay). It is selective for GnRHR over the cytochrome P450 (CYP) isoform CYP3A4 (IC50 = 56 µM) as well as a panel of 100 receptors, ion channels, enzymes, and transporters (IC50s = >10 µM). Elagolix...

Keywords:	4-[[(1R)-2-[5-(2-fluoro-3-methoxyphenyl)-3-[[2-fluoro-6-(trifluoromethyl)phenyl]methyl]-3,6-dihydro-4-methyl-2,6-dioxo-1(2...
Application:	Gonadotropin-releasing hormone receptor antagonist
CAS	832720-36-2
MW:	653.6 D

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