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Item number: Cay33931-1

AZD 5904 is an irreversible inhibitor of myeloperoxidase (MPO, IC50 = 0.2 µM in a cell-free assay). It enhances decreases in the mitochondrial membrane potential in, and the viability of, MOLM-14 acute myeloid leukemia (AML) cells when used in combination with cytarabine (Cay-16069). AZD 5904 (75 µmol/kg) prevents...

Keywords:	1,2,3,9-tetrahydro-3-[[(2R)-tetrahydro-2-furanyl]methyl]-2-thioxo-6H-purin-6-one
Application:	Myeloperoxidase inhibitor
CAS	618913-30-7
MW:	252.3 D

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