2 products were found matching "457639-26-8"!
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2,5-Dimethyl-celecoxib
Item number: AG-CR1-3599-M025
White solid. Soluble in DMSO, methanol or dichloromethane. Close structural analog of the selective cyclooxygenase-2 (COX-2) inhibitor celecoxib, that lacks COX-2 inhibitory function, Anti-proliferative, anti-tumorigenic and anti-angiogenic, Potent apoptosis inducer in many cancer cell lines, Down-regulates the...
| Keywords: | DMC, 2,5-Dimethylcelecoxib |
| Application: | Antiproliferative, Antitumorigenic, Antiangiogenic, Apoptosis inducer |
| CAS | 457639-26-8 |
| MW: | 395,4 D |
From 66.00€
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2,5-dimethyl Celecoxib
Item number: Cay10008006-10
2,5-dimethyl Celecoxib is a derivative of celecoxib (Cay-10008672) that does not inhibit COX-2 (IC50 = >100 µM). It does inhibit microsomal prostaglandin E synthase-1 (mPGES-1) in HeLa cells (IC50 = 15.6 µM) and reduces prostaglandin E2 (PGE2, Cay-14010) production in HeLa, A549, and HCA-7 cells (IC50s = 0.64, 0.83,...
| Keywords: | DMC, 4-[5-(2,5-dimethylphenyl)-3-(trifluoromethyl)-1H-pyrazol-1-yl]-benzenesulfonamide |
| Application: | mPGES-1 inhibitor |
| CAS | 457639-26-8 |
| MW: | 395.4 D |
From 66.00€
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