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p-nitro-Pifithrin-alpha
p-nitro-Pifithrin-alpha

Item number: Cay16209-5

Pifithrin-alpha (Cay-13326) is an inactivator of p53 that blocks p53-dependent transcriptional activation and apoptosis. p-nitro-Pifithrin-alpha is a cell-permeable analog of pifithrin-alpha. It blocks p53-mediated expression of p21/WAF1 and apoptosis in cortical neurons ten-fold more potently than pifithrin-alpha....
Keywords: p-nitro-PFT-alpha, 1-(4-nitrophenyl)-2-(4,5,6,7-tetrahydro-2-imino-3(2H)-benzothiazolyl)-ethanone, monohydrobromide
Application: Cell-permeable p53 inhibitor
CAS 389850-21-9
MW: 398.3 D
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