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Item number: Cay11715-1

Hypophyllanthin is an active principle of P. amarus, a plant studied for its potential to treat hepatotoxicity. In Caco-2 cells 100 µM hypophyllanthin has been shown to reversibly inhibit P-glycoprotein (also known as multidrug resistance protein 1 (MDR1)) function without effect on MDR2 activity.Formal Name:...

Keywords:	NSC 619044, (7S,8S,9R)-9-(3,4-dimethoxyphenyl)-6,7,8,9-tetrahydro-4-methoxy-7,8-bis(methoxymethyl)-naphtho[1,2-d]-1,3-dioxole
Application:	MDR1 inhibitor
CAS	33676-00-5
MW:	430.5 D

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