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Item number: Cay16870-1

R-7050 is a cell-permeable antagonist of signaling through the TNF-alpha receptor complex (EC50 = 0.631 µM). It blocks TNF-alpha-induced binding of TNF-alpha receptor I with TNF-alpha receptor-associated death domain protein and receptor interacting protein 1, which, in turn, prevents internalization of the receptor...

Keywords:	TNF-alpha Antagonist III, 8-chloro-4-(phenylthio)-1-(trifluoromethyl)-[1,2,4]triazolo[4,3-a]quinoxaline
Application:	Cell-permeable TNF-alpha receptor complex signaling antagonist
CAS	303997-35-5
MW:	380.8 D

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