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Item number: Cay27813-10

Monomethyl fumarate is an active metabolite of the immune modulator dimethyl fumarate (Cay-14714) that is rapidly formed from dimethyl fumarate by hydrolysis. It is an agonist of the hydroxycarboxylic acid 2 (HCA2) receptor/GPR109A with an EC50 value of 9.4 µM for inducing calcium accumulation in CHO cells...

Keywords:	Fumaric Acid monomethyl ester, 2E-butenedioic acid, 1-methyl ester
Application:	HCAR2 (GPR109A) agonist
CAS	2756-87-8
MW:	130.1 D

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Monomethyl fumarate

Item number: TGM-T12095-1mL

Description: Monomethyl fumarate is a potent agonist of GPR109A . Target: Drug Metabolite, GPR. Smiles: COC(=O)\C=C\C(O)=O. References: Tang H, et al. The psoriasis drug monomethylfumarate is a potent nicotinic acid receptor agonist. Biochem Biophys Res Commun. 2008 Oct 31,375(4):562-5.

Application:	Immunomodulator
CAS	2756-87-8
MW:	130.1 D

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