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Monomethyl fumarate
Monomethyl fumarate

Item number: Cay27813-10

Monomethyl fumarate is an active metabolite of the immune modulator dimethyl fumarate (Cay-14714) that is rapidly formed from dimethyl fumarate by hydrolysis. It is an agonist of the hydroxycarboxylic acid 2 (HCA2) receptor/GPR109A with an EC50 value of 9.4 µM for inducing calcium accumulation in CHO cells...
Keywords: Fumaric Acid monomethyl ester, 2E-butenedioic acid, 1-methyl ester
Application: HCAR2 (GPR109A) agonist
CAS 2756-87-8
MW: 130.1 D
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