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Item number: Cay28225-1

9c(i472) is an inhibitor of 15-lipoxygenase-1 (15-LO-1, IC50 = 0.19 µM). It decreases LPS- and IFN-gamma-induced NF-?B activity in RAW-Blue(TM) cells when used at concentrations of 0.2, 1, and 5 µM. 9c(i472) reduces LPS- and IFN-gamma-induced increases in Nos2 expression and lipid peroxidation in RAW 264.7 cells...

Keywords:	15-LOX-1 Inhibitor i472, 6-chloro-3-[(1E)-3-[[(2-methoxyphenyl)methyl]amino]-3-oxo-1-propen-1-yl]-1H-indole-2-carboxylic...
Application:	15-LOX-1 (ALOX15) inhibitor
CAS	2349374-37-2
MW:	412.9 D

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