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Item number: Cay29827-10

AZD 0364 is an inhibitor of ERK2 (IC50 = 50s = 30, 400, 300, and 300 nM, respectively). AZD 0364 inhibits cell growth in A549 non-small cell lung cancer cells (NSCLCs) when used in combination with AZD 6244 (Cay-11599). It reduces tumor growth and induces regression in a Calu-6 mouse xenograft model when...

Keywords:	(6R)-7-[(3,4-difluorophenyl)methyl]-6,7-dihydro-6-(methoxymethyl)-2-[5-methyl-2-[(1-methyl-1H-pyrazol-5-yl)amino]-4-pyrimi...
Application:	ERK2 inhibitor
CAS	2097416-76-5
MW:	494.5 D

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