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5-Methoxycarbonylamino-N-acetyltryptamine
5-Methoxycarbonylamino-N-acetyltryptamine

Item number: Cay39553-1

5-Methoxycarbonylamino-N-acetyltryptamine (5-MCA-NAT) is a melatonin (Cay-14427) derivative and a partial agonist of melatonin receptor 1 (MT1) and MT2. It inhibits forskolin-induced production of cAMP in CHO cells expressing human MT1 or MT2 (EC50s = 440 and 98 nM, respectively). In vivo, ocular administration of...
Keywords: 5-MCA-NAT, GR135531, MCA-NAT, N-[3-[2-(acetylamino)ethyl]-1H-indol-5-yl]-carbamic acid, methyl ester
Application: Melatonin receptor MTNR1A/B partial agonist
CAS 190277-13-5
MW: 275.3 D
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