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Item number: Cay19237-1

UNC3866 is an inhibitor of chromobox homolog 7 (CBX7, Kd = 97 nM). It also binds to CBX4 (Kd = 94 nM) but is greater than 6-fold selective over CBX2, 6, and 8 and the chromodomain Y family (CDY) chromodomains CDY1, L1b, and L2 (Kds = 0.61-6.3 µM). UNC3866 pretreatment (30 µM) of PC3 lysates completely inhibits...

Keywords:	N-[4-(1,1-dimethylethyl)benzoyl]-L-phenylalanyl-L-alanyl-L-leucyl-N6,N6-diethyl-L-lysyl-L-serine, methyl ester
Application:	CBX4 & CBX7 chromodomain antagonist
CAS	1872382-47-2
MW:	795 D

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