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Item number: Cay81510-10

1,4-PBIT is a potent inhibitor of purified human iNOS and nNOS with Ki values of 7.4 and 16 nM, respectively, compared to a Ki of 360 nM for human eNOS. Its inhibition in whole cells is greatly diminished, presumably to poor membrane permeability.Formal Name: S,S'-1,4-phenylene-bis(1,2-ethanediyl)bis-isothiourea,...

Keywords:	S,S'-1,4-phenylene-bis(1,2-ethanediyl)bis-isothiourea, dihydrobromide
Application:	iNOS inhibitor, nNOS inhibitor
CAS	157254-60-9
MW:	444.2 D

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