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PI-1840
PI-1840

Item number: Cay37331-10

PI-1840 is an inhibitor of chymotrypsin-like (CTL) proteasome activity (IC50 = 27 nM). It is selective for the CTL activity over the trypsin-like (TL) and peptidylglutamyl peptide hydrolyzing (PGPH) activities (IC50s = >100 µM for both), as well as for the 20S constitutive proteasome over the immunoproteasome (IC50s...
Keywords: N-(1-methylethyl)-2-(4-propylphenoxy)-N-[[3-(3-pyridinyl)-1,2,4-oxadiazol-5-yl]methyl]-acetamide
Application: Chymotrypsin-like proteasome activity inhibitor
CAS 1401223-22-0
MW: 394.5 D
From 81.00€ *
Review
PI-1840 [Proteasome Inhibitor]
PI-1840 [Proteasome Inhibitor]

Item number: AG-CR1-3675-M005

Synthetic. Chemical. CAS: 1401223-22-0. Formula: C22H26N4O3. MW: 394.5. Synthetic. Highly potent, selective and rapidly reversible non-covalent proteasome inhibitor. Targets the chymotrypsin-like beta5-subunit of the constitutive 20S proteasome (IC50=27nM), with minimal crossreactivity on the trypsin-like (beta2)...
Keywords: N-(1-Methylethyl)-2-(4-propylphenoxy)-N-[[3-(3-pyridinyl)-1,2,4-oxadiazol-5-yl]methyl]-acetamide
Application: Proteasome inhibitor
CAS 1401223-22-0
MW: 394,5 D
From 28.00€ *
Review