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I-SAP
I-SAP

Item number: Cay19021-100

I-SAP is a high affinity TP receptor antagonist. At physiologic pH, I-SAP produces platelet shape change, but not aggregation, with an EC50 value of 9.7 nM. I-SAP binds to human platelets with the maximum binding obtained between pH 6.5 and pH 7.4. In washed human platelets, the Kd for I-SAP is 468 pM at pH 7.4 and...
Keywords: Iodophenyl sulfonyl amino pinane Thromboxane A2, Iodophenyl sulfonyl amino pinane TXA2,...
Application: TP receptor antagonist
CAS 133538-58-6
MW: 531.4 D
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