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Item number: Cay20237-5

XL388 is an orally bioavailable and ATP-competitive inhibitor of mammalian target of rapamycin (mTOR, IC50 = 9.9 nM). It is selective for mTOR over a panel of more than 140 kinases, including various PI3Ks (IC50s = >3,000 nM). It inhibits mTOR complex 1 (mTORC1) and mTORC2 in vitro (IC50s = 8 and 166 nM,...

Keywords:	[7-(6-amino-3-pyridinyl)-2,3-dihydro-1,4-benzoxazepin-4(5H)-yl][3-fluoro-2-methyl-4-(methylsulfonyl)phenyl]-methanone
Application:	mTOR inhibitor
CAS	1251156-08-7
MW:	455.5 D

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XL-388

Item number: SYN-1186-M001

Soluble in DMSO. XL388 is a novel class of highly potent, selective, ATP-competitive, and orally bioavailable inhibitors of the mammalian target of rapamycin (mTOR) with an IC(50) of 9.9nM.

Keywords:	XL-388
Application:	mTOR inhibitor
CAS	1251156-08-7
MW:	455,5 D

From 205.00€ *

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