Alithea Genomics has developed an innovative RNA sequencing technology that makes generating RNA data accessible, fast and cost-effective for everyone. Such data can help to identify new diseases, determine biomarkers for clinical indications and develop effective therapies.
Biomol equips researchers with high-quality life science products from our specialized manufacturers - including the field of molecular biology, of course! Our new partner NZYtech is an expert in molecular biology solutions and is therefore a valuable addition to our portfolio.
PCR is probably the most widely used molecular biological method today and an absolute standard tool for researchers. A further development of classical PCR is qPCR (real-time quantitative PCR), which in addition to amplifying DNA also allows quantification of the amplified genetic material.
A key player in so-called RNA editing is the protein ADAR1 ("adenosine deaminase acting on RNA"), an RNA-specific adenosine deaminase that catalyzes the conversion of adenosine nucleoside building blocks to inosine. Mutations in the adar1 gene are associated with a variety of diseases, so the protein may be a promising target for various therapies.
The best-known variant of "lipid-based drug delivery systems" is the so-called lipid nanoparticle. In the second part of our LBDDS blog series, we will first provide an overview of the developmental history of LNPs and the "endosomal escape" – a crucial point in the transport pathway of LNPs. We will then go into the potential medical applications of LNPs – all the way to SARS-CoV-2 vaccination!