Due to the enormous potential, research with and on CAR-T cells is gaining momentum. In this article, we dive into the basics and latest developments to give you a comprehensive insight into CAR-T research. Find out how CAR-T cells are opening up new horizons in medicine with their important role in immunotherapy. With BPS Bioscience as our trusted supplier, we are here to support you with the latest tools to drive the future of CAR-T research.
A key player in so-called RNA editing is the protein ADAR1 ("adenosine deaminase acting on RNA"), an RNA-specific adenosine deaminase that catalyzes the conversion of adenosine nucleoside building blocks to inosine. Mutations in the adar1 gene are associated with a variety of diseases, so the protein may be a promising target for various therapies.
Reactive oxygen species (ROS) are oxygen-containing molecules and are often simplified as "oxygen radicals". The study of ROS plays an important role in understanding cellular stress and various pathologies such as cancer, diabetes and cardiovascular diseases.
Since the 1970s, flow cytometry has been used in research and industry to characterize and sort cell populations. Cells can be analyzed and separated on the basis of their physical and molecular properties. The range of applications for this technique is very wide. In this blog article, we want to give an insight into various possible applications of flow cytometry using specific examples from research. Antibodies play a major role in flow cytometry, which should ideally be validated in particular for this technique.
At the beginning of this year we would like to welcome a new supplier to the Biomol family and introduce them here in our blog: Atlas Antibodies! Read an exciting interview with CSO Dr. Caroline Kampf here.
Gliomas are among the most aggressive and lethal solid tumors of the central nervous system. They arise from the neoplastic transformation of glial cells. Despite continuous research, the molecular pathogenetic mechanisms of gliomas are not yet fully understood. Now you can obtain numerous antibodies from Atlas for your glioma research in our store.
T-cells are crucial to the body’s immune response to cancer, both endogenously and following therapeutic intervention. A T-cell marker panel that can identify subsets of tumor-associated T-cells allows scientists to identify and target subpopulations of T-cells playing unique roles in the immune response against a tumor.